Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 362
- +119 vs. Q1 2026
- Shares held
- 114.8M
- +40.3M (+54.1%) vs. Q1 2026
- Total value
- $5.35B
- +$3.94B (+280.1%) vs. Q1 2026
- New holders
- 148
- 117 more added
- Sold out
- 29
- 64 more reduced
5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alongside, LLC | 5,772 | $271.5K | 0.05% | +5,772 | New |
| CRA Financial Services, LLC | 5,846 | $275.0K | 0.03% | +5,846 | New |
| Beck Bode, LLC | 5,939 | $279.4K | 0.04% | +5,939 | New |
| Fiduciary Alliance LLC | 6,000 | $282.2K | 0.02% | +6,000 | New |
| Retirement Financial Solutions, LLC | 6,000 | $282.2K | 0.07% | +6,000 | New |
| Bailard, Inc. | 6,277 | $295.3K | 0.01% | +6,277 | New |
| Tower Research Capital LLC (TRC) | 6,308 | $296.7K | 0.01% | −997−13.6% | Reduced |
| Waldron Private Wealth LLC | 6,321 | $297.3K | 0.01% | +6,321 | New |
| Insigneo Advisory Services, LLC | 6,341 | $298.3K | 0.01% | +6,341 | New |
| AMG National Trust Bank | 6,369 | $299.6K | 0.01% | +6,369 | New |
| Sig Brokerage, LP | 6,563 | $308.7K | 0.05% | +6,563 | New |
| Chicago Partners Investment Group LLC | 7,299 | $313.3K | 0.01% | −2,008−21.6% | Reduced |
| Two Sigma Securities, LLC | 6,704 | $315.4K | 0.03% | +6,704 | New |
| Marex Group plc | 6,771 | $318.5K | 0.00% | −13,229−66.1% | Reduced |
| McAdam, LLC | 6,879 | $323.6K | 0.01% | +6,879 | New |
| Creative Planning | 6,906 | $324.9K | 0.00% | +6,906 | New |
| Chiron Capital Management, LLC | 7,000 | $329.3K | 0.30% | +7,000 | New |
| Jump Financial, LLC | 7,064 | $332.3K | 0.00% | +7,064 | New |
| Change Path, LLC | 7,202 | $338.8K | 0.01% | +7,202 | New |
| Centiva Capital, LP | 7,242 | $340.7K | 0.01% | +7,242 | New |
| EntryPoint Capital, LLC | 7,331 | $344.9K | 0.08% | +7,331 | New |
| Action Point Financial Planning, LLC | 7,483 | $352.0K | 0.04% | +7,483 | New |
| Abel Hall, LLC | 7,551 | $355.2K | 0.06% | +7,551 | New |
| Omers Administration Corp | 7,600 | $357.5K | 0.00% | +7,600 | New |
| CIBC Bancorp USA Inc. | 7,711 | $362.7K | 0.00% | +7,711 | New |
| Wealth Enhancement Advisory Services, LLC | 7,952 | $374.3K | 0.00% | +7,952 | New |
| Flagship Harbor Advisors, LLC | 7,966 | $374.7K | 0.01% | +7,966 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 8,295 | $390.2K | 0.00% | +8,295 | New |
| Bellevue Group AG | 8,391 | $394.7K | 0.01% | +8,391 | New |
| Fieldview Capital Management, LLC | 8,493 | $399.5K | 0.11% | +8,493 | New |
| Rafferty Asset Management, LLC | 8,548 | $402.1K | 0.00% | +8,548 | New |
| The PNC Financial Services Group, Inc. | 8,569 | $403.1K | 0.00% | +949+12.5% | Added |
| North Star Investment Management Corp. | 8,571 | $403.2K | 0.02% | +1,000+13.2% | Added |
| Fearless Solutions, LLC dba Best Invest | 8,804 | $414.1K | 0.22% | +8,804 | New |
| Gsa Capital Partners LLP | 9,073 | $427.0K | 0.03% | −9,082−50.0% | Reduced |
| Mangrove Partners | 9,079 | $427.1K | 0.03% | +9,079 | New |
| Diversify Wealth Management, LLC | 10,025 | $427.6K | 0.01% | −975−8.9% | Reduced |
| Diversify Advisory Services, LLC | 10,025 | $427.6K | 0.01% | +10,025 | New |
| Federation des caisses Desjardins du Quebec | 9,104 | $428.2K | 0.00% | −3,540−28.0% | Reduced |
| Quantbot Technologies LP | 9,230 | $434.2K | 0.02% | +9,230 | New |
| Commonwealth Equity Services, LLC | 9,450 | $444.5K | 0.00% | −801−7.8% | Reduced |
| First Trust Advisors LP | 9,527 | $448.1K | 0.00% | +9,527 | New |
| CIBC World Markets Inc. | 9,827 | $462.3K | 0.00% | −222−2.2% | Reduced |
| Principal Financial Group Inc | 9,952 | $468.1K | 0.00% | +9,952 | New |
| King Wealth | 10,000 | $470.0K | 0.05% | 00.0% | Unchanged |
| PSP Research LLC | 10,000 | $470.4K | 0.25% | −24,800−71.3% | Reduced |
| Sharpepoint LLC | 10,000 | $470.4K | 0.24% | 00.0% | Unchanged |
| Bank of Montreal | 10,030 | $471.8K | 0.00% | −2,106−17.4% | Reduced |
| Capital Fund Management S.A. | 10,128 | $476.4K | 0.00% | +10,128 | New |
| Engineers Gate Manager LP | 10,233 | $481.4K | 0.01% | −19,534−65.6% | Reduced |
| Mercer Global Advisors Inc | 10,278 | $483.5K | 0.00% | +10,278 | New |
| Entropy Technologies, LP | 10,688 | $502.8K | 0.02% | +10,688 | New |
| Teacher Retirement System of Texas | 11,072 | $520.8K | 0.00% | +772+7.5% | Added |
| Mount Yale Investment Advisors, LLC | 11,382 | $535.4K | 0.01% | +11,382 | New |
| Sanctuary Advisors, LLC | 11,502 | $541.1K | 0.00% | +36+0.3% | Added |
| Steward Partners Investment Advisory, LLC | 11,540 | $542.8K | 0.00% | −1,700−12.8% | Reduced |
| Glenmede Trust Co NA | 11,548 | $543.2K | 0.00% | +11,548 | New |
| Ameritas Investment Partners, Inc. | 11,736 | $552.1K | 0.01% | +4,095+53.6% | Added |
| Advisor Group Holdings, Inc. | 11,952 | $562.2K | 0.00% | +1,393+13.2% | Added |
| Heritage Wealth Management, Inc. | 12,000 | $564.5K | 0.28% | −2,375−16.5% | Reduced |
| Captrust Financial Advisors | 12,148 | $571.4K | 0.00% | +12,148 | New |
| Stifel Financial Corp | 12,225 | $575.1K | 0.00% | −401−3.2% | Reduced |
| Axq Capital, LP | 12,444 | $585.4K | 0.06% | +12,444 | New |
| State of Wyoming | 12,448 | $585.6K | 0.06% | +12,448 | New |
| Xponance, Inc. | 12,716 | $598.2K | 0.00% | +12,716 | New |
| Money Concepts Capital Corp | 13,000 | $611.5K | 0.03% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 13,220 | $621.9K | 0.14% | −8,507−39.2% | Reduced |
| Dymon Asia Capital (Singapore) Pte. Ltd. | 13,289 | $625.1K | 0.10% | +13,289 | New |
| Private Advisor Group, LLC | 13,336 | $627.3K | 0.00% | +13,336 | New |
| FORA Capital, LLC | 13,378 | $628.9K | 0.04% | +13,378 | New |
| Profund Advisors LLC | 13,571 | $638.4K | 0.02% | −625−4.4% | Reduced |
| Persistent Asset Partners Ltd | 13,778 | $648.1K | 0.20% | −2,083−13.1% | Reduced |
| Allianz Asset Management GmbH | 13,800 | $649.2K | 0.00% | +13,800 | New |
| Cetera Investment Advisers | 14,029 | $659.9K | 0.00% | −17,795−55.9% | Reduced |
| Amundi | 14,068 | $661.8K | 0.00% | −68−0.5% | Reduced |
| Pictet Asset Management Holding SA | 14,077 | $662.2K | 0.00% | +782+5.9% | Added |
| Twelve Points Wealth Management LLC | 14,245 | $670.1K | 0.13% | +2,000+16.3% | Added |
| Diadema Partners LP | 15,451 | $726.8K | 0.26% | +15,451 | New |
| Prudential Financial Inc | 15,500 | $729.1K | 0.00% | +15,500 | New |
| Cary Street Partners Financial LLC | 15,582 | $733.0K | 0.02% | +15,582 | New |
| Envestnet Asset Management Inc | 16,626 | $782.1K | 0.00% | +16,626 | New |
| Sequoia Financial Advisors, LLC | 17,258 | $811.8K | 0.00% | +13+0.1% | Added |
| Walleye Trading LLC | 18,450 | $867.9K | 0.01% | +13,036+240.8% | Added |
| Intech Investment Management LLC | 19,969 | $939.3K | 0.01% | −5,021−20.1% | Reduced |
| Birchview Capital, LP | 20,000 | $940.8K | 0.44% | +20,000 | New |
| Fore Capital, LLC | 20,000 | $940.8K | 1.25% | +20,000 | New |
| Concurrent Investment Advisors, LLC | 20,044 | $942.9K | 0.01% | −1,241−5.8% | Reduced |
| ProShare Advisors LLC | 20,615 | $969.7K | 0.00% | +1,884+10.1% | Added |
| Walleye Capital LLC | 20,643 | $971.0K | 0.00% | −14,842−41.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 21,358 | $1.00M | 0.06% | +1,166+5.8% | Added |
| TFB Advisors LLC | 21,523 | $1.01M | 0.45% | +21,523 | New |
| IFG Advisory, LLC | 22,043 | $1.04M | 0.04% | +22,043 | New |
| HighTower Advisors, LLC | 22,313 | $1.05M | 0.00% | +3,754+20.2% | Added |
| Raymond James Financial Inc | 22,401 | $1.05M | 0.00% | −1,312−5.5% | Reduced |
| Rathbone Brothers plc | 22,800 | $1.07M | 0.00% | −7,400−24.5% | Reduced |
| CI Private Wealth, LLC | 24,391 | $1.15M | 0.00% | +24,391 | New |
| Teachers Retirement System of the State of Kentucky | 24,500 | $1.15M | 0.01% | +24,500 | New |
| KLP Kapitalforvaltning AS | 25,000 | $1.18M | 0.00% | +8,000+47.1% | Added |
| ACT Capital Management, LLC | 25,000 | $1.18M | 0.77% | +25,000 | New |
| Janney Montgomery Scott LLC | 26,664 | $1.25M | 0.00% | +26,664 | New |