Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Definium Therapeutics, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 158
- +9 vs. Q2 2024
- Shares held
- 49.5M
- +13.3M (+36.9%) vs. Q2 2024
- Total value
- $281.6M
- +$21.1M (+8.1%) vs. Q2 2024
- New holders
- 30
- 50 more added
- Sold out
- 21
- 29 more reduced
3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Balyasny Asset Management LLC | 26,386 | $150.1K | 0.00% | +8,723+49.4% | Added |
| Manufacturers Life Insurance Company, The | 26,605 | $151.4K | 0.00% | −739−2.7% | Reduced |
| Janus Henderson Group PLC | 28,000 | $159.2K | 0.00% | 00.0% | Unchanged |
| Fore Capital, LLC | 30,000 | $170.7K | 0.33% | +15,000+100.0% | Added |
| Jane Street Group, LLC | 30,721 | $174.8K | 0.00% | −47,552−60.8% | Reduced |
| Caxton Corp | 34,073 | $193.9K | 0.80% | +3,690+12.1% | Added |
| Invesco Ltd. | 36,836 | $209.6K | 0.00% | +395+1.1% | Added |
| JPMorgan Chase & Co | 36,995 | $210.5K | 0.00% | +2,797+8.2% | Added |
| Corebridge Financial, Inc. | 38,495 | $219.0K | 0.00% | −238−0.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 39,508 | $224.8K | 0.00% | +39,508 | New |
| MetLife Investment Management | 42,549 | $242.1K | 0.00% | +42,549 | New |
| Citadel Advisors LLC | 42,843 | $243.8K | 0.00% | +25,263+143.7% | Added |
| Deutsche Bank AG | 46,879 | $266.7K | 0.00% | +10,189+27.8% | Added |
| LPL Financial LLC | 47,895 | $272.5K | 0.00% | +1,630+3.5% | Added |
| Kestra Private Wealth Services, LLC | 51,339 | $292.1K | 0.01% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 52,381 | $298.0K | 0.00% | +52,381 | New |
| Scotia Capital Inc. | 53,951 | $306.8K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 56,688 | $323.0K | 0.00% | −10,210−15.3% | Reduced |
| Legal & General Group Plc | 57,675 | $328.2K | 0.00% | +4,442+8.3% | Added |
| California State Teachers Retirement System | 58,484 | $332.8K | 0.00% | +2,184+3.9% | Added |
| XTX Topco Ltd | 59,222 | $337.0K | 0.02% | +59,222 | New |
| Ikarian Capital, LLC | 62,481 | $355.5K | 0.11% | −100,000−61.5% | Reduced |
| Alyeska Investment Group, L.P. | 66,694 | $379.5K | 0.00% | +66,694 | New |
| UBS Asset Management Americas Inc | 70,353 | $400.3K | 0.00% | −7,726−9.9% | Reduced |
| Alliancebernstein L.P. | 75,330 | $428.6K | 0.00% | 00.0% | Unchanged |
| Millennium Management LLC | 79,210 | $450.7K | 0.00% | +79,210 | New |
| Squarepoint Ops LLC | 80,121 | $455.9K | 0.00% | +80,121 | New |
| Citigroup Inc | 84,496 | $480.8K | 0.00% | +58,591+226.2% | Added |
| Rhumbline Advisers | 95,827 | $545.2K | 0.00% | +1,711+1.8% | Added |
| Data Collective IV GP, LLC | 100,350 | $571.0K | 0.35% | 00.0% | Unchanged |
| AdvisorShares Investments LLC | 109,166 | $621.2K | 0.12% | −15,000−12.1% | Reduced |
| Moloney Securities Asset Management, LLC | 115,511 | $657.3K | 0.09% | −19,800−14.6% | Reduced |
| Swiss National Bank | 119,900 | $682.2K | 0.00% | +9,000+8.1% | Added |
| UBS Group AG | 128,298 | $730.0K | 0.00% | +71,810+127.1% | Added |
| Barclays PLC | 136,098 | $774.4K | 0.00% | +91,271+203.6% | Added |
| Goldman Sachs Group Inc | 169,949 | $967.0K | 0.00% | +100,435+144.5% | Added |
| Wellington Management Group LLP | 185,722 | $1.06M | 0.00% | +109,152+142.6% | Added |
| Bank of New York Mellon Corp | 189,783 | $1.08M | 0.00% | −56,425−22.9% | Reduced |
| Nuveen Asset Management, LLC | 277,478 | $1.58M | 0.00% | +73,338+35.9% | Added |
| Two Sigma Investments, LP | 279,039 | $1.59M | 0.00% | −404,648−59.2% | Reduced |
| Bank of America Corp | 312,591 | $1.78M | 0.00% | +236,833+312.6% | Added |
| Morgan Stanley | 355,619 | $2.02M | 0.00% | +197,638+125.1% | Added |
| Charles Schwab Investment Management Inc | 602,544 | $3.43M | 0.00% | +46,187+8.3% | Added |
| Northern Trust Corp | 608,277 | $3.46M | 0.00% | +424,363+230.7% | Added |
| Ally Bridge Group (NY) LLC | 788,508 | $4.49M | 2.40% | −176,918−18.3% | Reduced |
| AWM Investment Company, Inc. | 853,000 | $4.85M | 0.59% | +20,000+2.4% | Added |
| Woodline Partners LP | 1,002,544 | $5.70M | 0.05% | +1,294+0.1% | Added |
| Tri Locum Partners LP | 1,662,953 | $9.46M | 2.27% | +1,280,898+335.3% | Added |
| Geode Capital Management, LLC | 1,677,702 | $9.55M | 0.00% | +162,933+10.8% | Added |
| State Street Corp | 1,814,829 | $10.3M | 0.00% | +9,782+0.5% | Added |
| Vanguard Group Inc | 1,948,307 | $11.1M | 0.00% | +206,904+11.9% | Added |
| Marshall Wace, LLP | 2,287,865 | $13.0M | 0.02% | +127,662+5.9% | Added |
| Octagon Capital Advisors LP | 3,018,000 | $17.2M | 2.75% | +865,000+40.2% | Added |
| Driehaus Capital Management LLC | 3,894,127 | $22.2M | 0.19% | +1,355,717+53.4% | Added |
| Blackstone Group Inc. | 3,912,479 | $22.3M | 0.10% | +2,014,154+106.1% | Added |
| BlackRock, Inc. | 5,664,033 | $32.2M | 0.00% | +5,664,033 | New |
| Deep Track Capital, LP | 7,065,099 | $40.2M | 1.28% | +961,282+15.7% | Added |
| Commodore Capital LP | 8,000,000 | $45.5M | 2.84% | +854,112+12.0% | Added |
| Artal Group S.A. | 0 | $0 | 0.00% | −1,007,875−100.0% | Sold out |
| Alpine Global Management, LLC | 0 | $0 | 0.00% | −68,176−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −44,365−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −35,508−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −33,133−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −32,062−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −18,487−100.0% | Sold out |
| Bridgewealth Advisory Group, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Thrivent Financial for Lutherans | 0 | $0 | 0.00% | −10,027−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −8,841−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −6,600−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −1,577−100.0% | Sold out |
| Opal Wealth Advisors, LLC | 0 | $0 | 0.00% | −1,101−100.0% | Sold out |
| Wolff Wiese Magana LLC | 0 | $0 | 0.00% | −206−100.0% | Sold out |
| Banque Cantonale Vaudoise | 0 | $0 | 0.00% | −66−100.0% | Sold out |
| New Millennium Group LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Signature Resources Capital Management, LLC | 0 | $0 | 0.00% | −53−100.0% | Sold out |
| American Capital Advisory, LLC | 0 | $0 | 0.00% | −33−100.0% | Sold out |
| Castleview Partners, LLC | 0 | $0 | 0.00% | −16−100.0% | Sold out |
| ZRC Wealth Management, LLC | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| PrairieView Partners, LLC | 0 | $0 | 0.00% | −4−100.0% | Sold out |
| BlackRock Inc. | – | – | – | – | Not filed |
| Emfo, LLC | – | – | – | – | Not filed |
| JJJ Advisors Inc. | – | – | – | – | Not filed |