Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 159
- −16 vs. Q4 2021
- Shares held
- 48.4M
- −3.55M (−6.8%) vs. Q4 2021
- Total value
- $53.6M
- −$18.4M (−25.6%) vs. Q4 2021
- New holders
- 32
- 34 more added
- Sold out
- 48
- 41 more reduced
1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Bank of America Corp | 47,463 | $52.0K | 0.00% | −107,995−69.5% | Reduced |
| Toronto Dominion Bank | 45,523 | $52.0K | 0.00% | +4,600+11.2% | Added |
| State Board of Administration of Florida Retirement System | 48,230 | $53.0K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 47,944 | $53.0K | 0.00% | +47,944 | New |
| Stifel Financial Corp | 49,740 | $56.0K | 0.00% | +3,500+7.6% | Added |
| Two Sigma Advisers, LP | 52,000 | $58.0K | 0.00% | −4,400−7.8% | Reduced |
| Barclays PLC | 52,281 | $58.0K | 0.00% | +52,281 | New |
| Creative Planning | 55,495 | $62.0K | 0.00% | −2,585−4.5% | Reduced |
| Principal Financial Group Inc | 58,480 | $65.0K | 0.00% | −709−1.2% | Reduced |
| ProShare Advisors LLC | 60,391 | $67.0K | 0.00% | −15,621−20.6% | Reduced |
| Wells Fargo & Company | 71,163 | $79.0K | 0.00% | −130,566−64.7% | Reduced |
| Gofen & Glossberg LLC | 72,500 | $80.0K | 0.00% | 00.0% | Unchanged |
| Audent Global Asset Management, LLC | 78,000 | $87.0K | 0.05% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 78,132 | $87.0K | 0.00% | +43,337+124.5% | Added |
| STRS Ohio | 79,800 | $88.0K | 0.00% | 00.0% | Unchanged |
| Scotia Capital Inc. | 83,783 | $93.0K | 0.00% | −3,825−4.4% | Reduced |
| Legal & General Group Plc | 84,554 | $96.0K | 0.00% | +30,064+55.2% | Added |
| Royal Bank of Canada | 92,643 | $103.0K | 0.00% | −51,034−35.5% | Reduced |
| Parallax Volatility Advisers, L.P. | 99,901 | $111.0K | 0.00% | +46,338+86.5% | Added |
| Fore Capital, LLC | 100,000 | $111.0K | 0.13% | +100,000 | New |
| Cresset Asset Management, LLC | 101,100 | $112.0K | 0.00% | −100,000−49.7% | Reduced |
| Ikarian Capital, LLC | 105,958 | $118.0K | 0.04% | +5,958+6.0% | Added |
| HighTower Advisors, LLC | 104,975 | $119.0K | 0.00% | +45,747+77.2% | Added |
| Invesco Ltd. | 133,867 | $149.0K | 0.00% | −13,127−8.9% | Reduced |
| Manufacturers Life Insurance Company, The | 135,904 | $150.9K | 0.00% | −41,852−23.5% | Reduced |
| California State Teachers Retirement System | 137,970 | $153.0K | 0.00% | −50,099−26.6% | Reduced |
| MetLife Investment Management | 146,176 | $162.3K | 0.00% | +7,857+5.7% | Added |
| JPMorgan Chase & Co | 151,310 | $168.0K | 0.00% | +16,666+12.4% | Added |
| Bank of Montreal | 146,833 | $175.0K | 0.00% | +103+0.1% | Added |
| American International Group, Inc. | 159,905 | $177.0K | 0.00% | −25,009−13.5% | Reduced |
| tru Independence LLC | 167,293 | $183.0K | 0.05% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 185,625 | $206.0K | 0.00% | +19,423+11.7% | Added |
| New York State Common Retirement Fund | 206,560 | $229.0K | 0.00% | +302+0.1% | Added |
| Man Group plc | 219,780 | $244.0K | 0.00% | +110,380+100.9% | Added |
| MMCAP International Inc. SPC | 240,300 | $267.0K | 0.02% | +240,300 | New |
| Credit Suisse AG | 279,053 | $309.0K | 0.00% | +63,963+29.7% | Added |
| Alliancebernstein L.P. | 291,800 | $324.0K | 0.00% | +1,100+0.4% | Added |
| Rhumbline Advisers | 301,676 | $335.0K | 0.00% | −8,267−2.7% | Reduced |
| Jane Street Group, LLC | 297,788 | $338.0K | 0.00% | +122,583+70.0% | Added |
| Goldman Sachs Group Inc | 347,777 | $386.0K | 0.00% | +119,075+52.1% | Added |
| Deutsche Bank AG | 366,292 | $406.0K | 0.00% | +34,574+10.4% | Added |
| Penserra Capital Management LLC | 480,853 | $442.0K | 0.01% | +238,737+98.6% | Added |
| Millennium Management LLC | 436,336 | $484.0K | 0.00% | −639,817−59.5% | Reduced |
| Group One Trading, L.P. | 535,205 | $594.0K | 0.01% | +59,346+12.5% | Added |
| AdvisorShares Investments LLC | 649,168 | $721.0K | 0.12% | +231,646+55.5% | Added |
| Two Sigma Investments, LP | 677,780 | $752.0K | 0.00% | −445,986−39.7% | Reduced |
| Susquehanna International Group, LLP | 683,954 | $759.0K | 0.00% | −369,884−35.1% | Reduced |
| Charles Schwab Investment Management Inc | 718,559 | $798.0K | 0.00% | −30,829−4.1% | Reduced |
| Bank of New York Mellon Corp | 936,388 | $1.04M | 0.00% | +16,746+1.8% | Added |
| Swiss National Bank | 951,100 | $1.08M | 0.00% | +178,300+23.1% | Added |
| Citadel Advisors LLC | 1,200,074 | $1.33M | 0.00% | −460,676−27.7% | Reduced |
| Busey Wealth Management | 1,248,201 | $1.39M | 0.06% | 00.0% | Unchanged |
| Data Collective IV GP, LLC | 1,505,248 | $1.67M | 0.35% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,903,150 | $2.11M | 0.00% | −71,849−3.6% | Reduced |
| Morgan Stanley | 1,974,299 | $2.19M | 0.00% | −425,584−17.7% | Reduced |
| Northern Trust Corp | 2,272,017 | $2.52M | 0.00% | −267,190−10.5% | Reduced |
| Geode Capital Management, LLC | 2,822,682 | $3.13M | 0.00% | −86,053−3.0% | Reduced |
| State Street Corp | 6,145,503 | $6.82M | 0.00% | +416,765+7.3% | Added |
| BlackRock Inc. | 16,434,210 | $18.2M | 0.00% | −631,364−3.7% | Reduced |
| LPL Financial LLC | 0 | $0 | 0.00% | −387,205−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −167,211−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −140,000−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −134,563−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −98,829−100.0% | Sold out |
| Ground Swell Capital, LLC | 0 | $0 | 0.00% | −63,698−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −62,146−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −57,608−100.0% | Sold out |
| First Republic Investment Management, Inc. | 0 | $0 | 0.00% | −37,500−100.0% | Sold out |
| Jaffetilchin Investment Partners, LLC | 0 | $0 | 0.00% | −36,855−100.0% | Sold out |
| Wedbush Securities Inc | 0 | $0 | 0.00% | −36,000−100.0% | Sold out |
| Wolverine Trading, LLC | 0 | $0 | 0.00% | −33,479−100.0% | Sold out |
| Csenge Advisory Group | 0 | $0 | 0.00% | −12,112−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −28,219−100.0% | Sold out |
| IHT Wealth Management, LLC | 0 | $0 | 0.00% | −27,500−100.0% | Sold out |
| Private Advisor Group, LLC | 0 | $0 | 0.00% | −25,710−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −23,578−100.0% | Sold out |
| CWM, LLC | 0 | $0 | 0.00% | −19,642−100.0% | Sold out |
| Gerber Kawasaki Wealth & Investment Management | 0 | $0 | 0.00% | −15,540−100.0% | Sold out |
| Bard Financial Services, Inc. | 0 | $0 | 0.00% | −15,000−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −19,035−100.0% | Sold out |
| Schechter Investment Advisors, LLC | 0 | $0 | 0.00% | −13,006−100.0% | Sold out |
| Sandy Spring Bank | 0 | $0 | 0.00% | −12,152−100.0% | Sold out |
| Bank Julius Baer & Co. Ltd, Zurich | 0 | $0 | 0.00% | −12,555−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −11,940−100.0% | Sold out |
| Profund Advisors LLC | 0 | $0 | 0.00% | −11,772−100.0% | Sold out |
| Platform Technology Partners | 0 | $0 | 0.00% | −11,250−100.0% | Sold out |
| Edmond de Rothschild Holding S.A. | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Aries Wealth Management | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −6,081−100.0% | Sold out |
| South State Corp. | 0 | $0 | 0.00% | −5,275−100.0% | Sold out |
| Cardinal Capital Management, Inc. | 0 | $0 | 0.00% | −3,750−100.0% | Sold out |
| Concord Wealth Partners | 0 | $0 | 0.00% | −3,510−100.0% | Sold out |
| Steward Partners Investment Advisory, LLC | 0 | $0 | 0.00% | −2,700−100.0% | Sold out |
| Rinkey Investments | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| The PNC Financial Services Group, Inc. | 0 | $0 | 0.00% | −2,395−100.0% | Sold out |
| Glassman Wealth Services | 0 | $0 | 0.00% | −2,500−100.0% | Sold out |
| Henrickson Nauta Wealth Advisors, Inc. | 0 | $0 | 0.00% | −3,000−100.0% | Sold out |
| Westside Investment Management, Inc. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −436−100.0% | Sold out |
| Private Ocean, LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |