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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
206
+37 vs. Q1 2026
Shares held
115.0M
+5.82M (+5.3%) vs. Q1 2026
Total value
$2.07B
+$549.0M (+36.2%) vs. Q1 2026
New holders
50
71 more added
Sold out
13
60 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 206 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ2 2026: $2.07B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q1 2026.

Institutions holding AMLX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Mirae Asset Global ETFs Holdings Ltd.42,351$760.6K0.00%−202−0.5%Reduced
Aquatic Capital Management LLC39,425$708.1K0.02%+39,425New
Gsa Capital Partners LLP39,241$705.0K0.04%+39,241New
Manufacturers Life Insurance Company, The37,828$679.4K0.00%−953−2.5%Reduced
Boothbay Fund Management, LLC36,060$647.6K0.01%+36,060New
Jennison Associates LLC35,841$643.7K0.00%+35,841New
Tudor Investment Corp Et Al35,410$636.0K0.00%+4,076+13.0%Added
New York State Common Retirement Fund34,300$616.0K0.00%+12,400+56.6%Added
Optimize Financial Inc31,890$572.7K0.21%−111−0.3%Reduced
Sound Capital Solutions LLC31,890$572.7K0.13%+31,890New
Jain Global LLC28,770$516.7K0.01%+28,770New
Numerai GP LLC28,665$514.8K0.04%−19,888−41.0%Reduced
Canada Pension Plan Investment Board27,600$495.7K0.00%+27,600New
Police & Firemen's Retirement System of New Jersey27,123$487.1K0.00%+3,371+14.2%Added
Jump Financial, LLC26,891$483.0K0.00%+26,891New
XTX Topco Ltd25,864$464.5K0.01%+25,864New
Guggenheim Capital LLC25,387$456.0K0.00%−126−0.5%Reduced
Maven Securities LTD25,000$449.0K0.03%−25,000−50.0%Reduced
HRT Financial LP23,870$428.0K0.00%+23,870New
State of New Jersey Common Pension Fund D23,232$417.2K0.00%+713+3.2%Added
Martingale Asset Management L P22,573$405.4K0.01%+22,573New
Virtus Investment Advisers, Inc.22,426$402.8K0.09%+1,611+7.7%Added
Parsons Capital Management Inc21,645$388.7K0.02%00.0%Unchanged
AQR Capital Management LLC20,819$373.9K0.00%−8,270−28.4%Reduced
Profund Advisors LLC20,710$372.0K0.01%+3,558+20.7%Added
Brown Advisory Inc19,930$357.9K0.00%00.0%Unchanged
JustInvest LLC19,880$357.0K0.00%−4,192−17.4%Reduced
Arizona State Retirement System19,825$356.1K0.00%+1,726+9.5%Added
Intech Investment Management LLC19,775$355.2K0.00%−5,146−20.6%Reduced
SEI Investments Co19,750$354.7K0.00%−65,529−76.8%Reduced
Premier Path Wealth Partners, LLC18,265$328.0K0.04%−2,000−9.9%Reduced
Voya Investment Management LLC17,847$320.5K0.00%+2,620+17.2%Added
Vanguard Investments Australia, Ltd.17,713$318.1K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.17,695$317.8K0.02%−1,793−9.2%Reduced
KLP Kapitalforvaltning AS17,400$312.5K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)16,956$304.5K0.00%−23,834−58.4%Reduced
BNP Paribas Arbitrage, SA16,577$297.7K0.00%−4,563−21.6%Reduced
Creative Planning15,881$285.2K0.00%−2,002−11.2%Reduced
ProShare Advisors LLC15,685$281.7K0.00%−2,469−13.6%Reduced
Prudential Financial Inc15,110$271.4K0.00%+990+7.0%Added
HSBC Holdings PLC14,554$269.0K0.00%+3,140+27.5%Added
Rafferty Asset Management, LLC14,758$265.1K0.00%+14,758New
Royal Bank of Canada14,649$263.0K0.00%+2,266+18.3%Added
Seven Fleet Capital Management LP14,540$261.1K0.04%−2,131−12.8%Reduced
STRS Ohio14,000$251.4K0.00%+10,600+311.8%Added
Glenmede Trust Co NA13,685$245.8K0.00%+13,685New
Amundi12,895$231.6K0.00%00.0%Unchanged
Great Lakes Advisors, LLC12,807$230.0K0.00%+2,427+23.4%Added
Graham Capital Management, L.P.12,364$222.1K0.01%+12,364New
Magnetar Financial LLC11,722$210.5K0.00%+11,722New
Brevan Howard Capital Management LP11,611$208.5K0.00%+11,611New
PSP Research LLC10,838$194.7K0.10%00.0%Unchanged
Pictet Asset Management Holding SA10,768$193.4K0.00%00.0%Unchanged
Victory Capital Management Inc10,707$192.3K0.00%+63+0.6%Added
Susquehanna International Group, LLP10,339$185.7K0.00%−29,463−74.0%Reduced
Harvest Investment Services, LLC10,214$183.4K0.03%+10,214New
Valeo Financial Advisors, LLC10,045$180.4K0.00%+45+0.4%Added
Ameritas Investment Partners, Inc.8,346$149.9K0.00%+1,143+15.9%Added
Tower Research Capital LLC (TRC)7,934$142.5K0.00%+21+0.3%Added
Mirae Asset Global Investments Co., Ltd.4,973$89.3K0.00%−755−13.2%Reduced
Fulcrum Asset Management LLP4,400$82.3K0.01%+4,400New
US Bancorp3,639$65.4K0.00%+1,576+76.4%Added
GF Fund Management Co. Ltd.2,326$41.8K0.00%−129−5.3%Reduced
SRS Capital Advisors, Inc.2,235$40.1K0.00%+741+49.6%Added
State of Wyoming2,223$39.9K0.00%+340+18.1%Added
KBC Group NV1,863$33.0K0.00%00.0%Unchanged
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,803$32.4K0.00%00.0%Unchanged
Group One Trading, L.P.1,624$29.2K0.00%+1,624New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,351$24.3K0.00%−67−4.7%Reduced
Rockefeller Capital Management L.P.1,274$22.9K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,163$20.9K0.00%+241+26.1%Added
Steward Partners Investment Advisory, LLC1,000$18.0K0.00%00.0%Unchanged
Fifth Third Bancorp972$17.5K0.00%+217+28.7%Added
Kemnay Advisory Services Inc.928$16.7K0.00%+928New
Westfuller Advisors, LLC819$14.7K0.01%00.0%Unchanged
Eastern Bank721$12.9K0.00%+521+260.5%Added
Strive Financial Group ,LLC650$11.7K0.01%+650New
Jones Financial Companies LLLP597$10.6K0.00%+327+121.1%Added
Advisor Group Holdings, Inc.483$8.67K0.00%−45−8.5%Reduced
GAMMA Investing LLC433$7.78K0.00%+16+3.8%Added
Silver Grove Financial Group, Inc.424$7.62K0.00%+424New
Massmutual Trust Co FSB420$7.54K0.00%+138+48.9%Added
The PNC Financial Services Group, Inc.406$7.29K0.00%+123+43.5%Added
Aster Capital Management (DIFC) Ltd393$7.06K0.00%+393New
EverSource Wealth Advisors, LLC350$6.29K0.00%+324+1,246.2%Added
Los Angeles Capital Management LLC325$5.84K0.00%00.0%Unchanged
Sterling Capital Management LLC323$5.80K0.00%−814−71.6%Reduced
J.Safra Asset Management Corp315$5.66K0.00%−62−16.4%Reduced
UMA Financial Services, Inc.274$4.92K0.00%00.0%Unchanged
Farther Finance Advisors, LLC259$4.65K0.00%+237+1,077.3%Added
Optiver Holding B.V.220$3.95K0.00%+220New
Picton Mahoney Asset Management189$3.39K0.00%+189New
Caption Management, LLC174$3.13K0.00%+174New
Larson Financial Group LLC142$2.55K0.00%−59−29.4%Reduced
Quarry LP139$2.50K0.00%+139New
Signaturefd, LLC93$1.67K0.00%−161−63.4%Reduced
Harbour Investments, Inc.90$1.62K0.00%00.0%Unchanged
Catherine Avery Investment Management LLC87$1.56K0.00%+87New
Covestor Ltd33$1.00K0.00%+24+266.7%Added
Rothschild Investment LLC55$9880.00%00.0%Unchanged