Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 122
- +13 vs. Q3 2024
- Shares held
- 49.8M
- +6.68M (+15.5%) vs. Q3 2024
- Total value
- $188.3M
- +$48.6M (+34.8%) vs. Q3 2024
- New holders
- 33
- 35 more added
- Sold out
- 20
- 40 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Acadian Asset Management LLC | 611,926 | $2.31M | 0.01% | −1,158,271−65.4% | Reduced |
| UBS Group AG | 643,524 | $2.43M | 0.00% | +414,448+180.9% | Added |
| Two Sigma Investments, LP | 651,517 | $2.46M | 0.01% | +284,280+77.4% | Added |
| FMR LLC | 731,356 | $2.76M | 0.00% | +510,355+230.9% | Added |
| Jane Street Group, LLC | 765,475 | $2.89M | 0.00% | +421,302+122.4% | Added |
| Qube Research & Technologies Ltd | 780,566 | $2.95M | 0.00% | +596,672+324.5% | Added |
| Alyeska Investment Group, L.P. | 823,420 | $3.11M | 0.01% | −1,200,000−59.3% | Reduced |
| Susquehanna International Group, LLP | 868,382 | $3.28M | 0.00% | +462,225+113.8% | Added |
| Saturn V Capital Management LLC | 889,073 | $3.36M | 1.32% | +889,073 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 1,263,353 | $4.78M | 0.02% | +382,608+43.4% | Added |
| Nantahala Capital Management, LLC | 1,452,153 | $5.49M | 0.38% | +47,589+3.4% | Added |
| Standard Life Aberdeen plc | 1,722,805 | $6.51M | 0.01% | −249,437−12.6% | Reduced |
| Boxer Capital Management, LLC | 1,750,000 | $6.62M | 0.56% | +1,750,000 | New |
| Goldman Sachs Group Inc | 1,859,896 | $7.03M | 0.00% | +246,033+15.2% | Added |
| 683 Capital Management, LLC | 1,930,000 | $7.30M | 0.72% | −70,000−3.5% | Reduced |
| Citadel Advisors LLC | 1,970,704 | $7.45M | 0.01% | +71,144+3.7% | Added |
| Almitas Capital LLC | 2,032,370 | $7.68M | 1.69% | +43,807+2.2% | Added |
| BlackRock, Inc. | 2,278,934 | $8.61M | 0.00% | −269,272−10.6% | Reduced |
| Bank of America Corp | 2,426,263 | $9.17M | 0.00% | +1,513,748+165.9% | Added |
| Vanguard Group Inc | 2,692,489 | $10.2M | 0.00% | −397,156−12.9% | Reduced |
| TCG Crossover Management, LLC | 4,643,812 | $17.6M | 1.72% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 6,774,348 | $25.6M | 0.71% | +4,648,699+218.7% | Added |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −1,150,221−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −221,626−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −220,906−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −188,465−100.0% | Sold out |
| Shay Capital LLC | 0 | $0 | 0.00% | −117,328−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −106,219−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −81,291−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −67,956−100.0% | Sold out |
| Savant Capital, LLC | 0 | $0 | 0.00% | −57,565−100.0% | Sold out |
| Legacy Advisors, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Bank of New York Mellon Corp | 0 | $0 | 0.00% | −23,679−100.0% | Sold out |
| Premier Path Wealth Partners, LLC | 0 | $0 | 0.00% | −20,265−100.0% | Sold out |
| Aries Wealth Management | 0 | $0 | 0.00% | −15,000−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −13,104−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −10,700−100.0% | Sold out |
| Atria Wealth Solutions, Inc. | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −7,500−100.0% | Sold out |
| nVerses Capital, LLC | 0 | $0 | 0.00% | −2,100−100.0% | Sold out |
| Ronald Blue Trust, Inc. | 0 | $0 | 0.00% | −2,104−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Ghost Tree Capital, LLC | – | – | – | – | Not filed |