Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 122
- +13 vs. Q3 2024
- Shares held
- 49.8M
- +6.68M (+15.5%) vs. Q3 2024
- Total value
- $188.3M
- +$48.6M (+34.8%) vs. Q3 2024
- New holders
- 33
- 35 more added
- Sold out
- 20
- 40 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 1 | $4 | 0.00% | +1 | New |
| EverSource Wealth Advisors, LLC | 25 | $95 | 0.00% | +25 | New |
| The PNC Financial Services Group, Inc. | 53 | $200 | 0.00% | −43−44.8% | Reduced |
| Salem Investment Counselors Inc | 55 | $208 | 0.00% | 00.0% | Unchanged |
| Catherine Avery Investment Management LLC | 87 | $329 | 0.00% | +87 | New |
| Harbour Investments, Inc. | 90 | $340 | 0.00% | +90 | New |
| Daiwa Securities Group Inc. | 266 | $1.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 300 | $1.13K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 400 | $1.51K | 0.00% | +400 | New |
| Nisa Investment Advisors, LLC | 495 | $1.87K | 0.00% | −250−33.6% | Reduced |
| Dunhill Financial, LLC | 600 | $2.27K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 638 | $2.41K | 0.00% | +423+196.7% | Added |
| CWM, LLC | 890 | $3.00K | 0.00% | 00.0% | Unchanged |
| Oliver Lagore Vanvalin Investment Group | 1,100 | $4.16K | 0.00% | −500−31.3% | Reduced |
| BNP Paribas Arbitrage, SA | 1,149 | $4.34K | 0.00% | +1,149 | New |
| GF Fund Management Co. Ltd. | 1,439 | $5.44K | 0.00% | +1,439 | New |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,803 | $6.29K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 2,000 | $7.56K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 2,193 | $8.29K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,284 | $8.84K | 0.00% | −178−7.2% | Reduced |
| Walleye Trading LLC | 2,649 | $10.0K | 0.00% | +2,649 | New |
| Advisors Asset Management, Inc. | 3,902 | $14.8K | 0.00% | −3,751−49.0% | Reduced |
| US Bancorp | 4,000 | $15.1K | 0.00% | +4,000 | New |
| Point72 (DIFC) Ltd | 4,796 | $18.1K | 0.00% | +4,796 | New |
| Russell Investments Group, Ltd. | 5,069 | $19.2K | 0.00% | −1,920−27.5% | Reduced |
| R Squared Ltd | 6,370 | $24.1K | 0.02% | +6,370 | New |
| Gsa Capital Partners LLP | 10,639 | $40.0K | 0.00% | +10,639 | New |
| Vident Advisory, LLC | 10,862 | $41.1K | 0.00% | −4,710−30.2% | Reduced |
| HSBC Holdings PLC | 11,566 | $43.3K | 0.00% | −50,121−81.3% | Reduced |
| Fox Run Management, L.L.C. | 11,788 | $44.6K | 0.01% | +11,788 | New |
| Bank of Nova Scotia | 11,884 | $44.9K | 0.00% | +1,188+11.1% | Added |
| Royal Bank of Canada | 11,874 | $45.0K | 0.00% | +24+0.2% | Added |
| Alpine Global Management, LLC | 12,017 | $45.4K | 0.01% | +12,017 | New |
| Rpo LLC | 12,136 | $45.9K | 0.06% | +12,136 | New |
| EntryPoint Capital, LLC | 13,909 | $52.6K | 0.02% | +13,909 | New |
| China Universal Asset Management Co., Ltd. | 14,535 | $54.9K | 0.01% | +1,441+11.0% | Added |
| Y-Intercept (Hong Kong) Ltd | 14,809 | $56.0K | 0.00% | +14,809 | New |
| SG Americas Securities, LLC | 15,958 | $60.0K | 0.00% | −41,428−72.2% | Reduced |
| State of Wyoming | 16,077 | $60.8K | 0.01% | −9,700−37.6% | Reduced |
| Engineers Gate Manager LP | 17,637 | $66.7K | 0.00% | +17,637 | New |
| JustInvest LLC | 17,724 | $67.0K | 0.00% | +1,132+6.8% | Added |
| Simplex Trading, LLC | 17,819 | $67.0K | 0.00% | −93,909−84.1% | Reduced |
| Prudential Financial Inc | 19,400 | $73.3K | 0.00% | 00.0% | Unchanged |
| Wedbush Securities Inc | 19,914 | $75.0K | 0.00% | +19,914 | New |
| Brown Advisory Inc | 19,930 | $75.3K | 0.00% | −20−0.1% | Reduced |
| Marex Group plc | 20,000 | $75.6K | 0.00% | −20,000−50.0% | Reduced |
| Parsons Capital Management Inc | 21,645 | $81.8K | 0.00% | −300−1.4% | Reduced |
| Tudor Investment Corp Et Al | 33,687 | $127.3K | 0.00% | +33,687 | New |
| Centiva Capital, LP | 33,831 | $127.9K | 0.00% | +33,831 | New |
| Guggenheim Capital LLC | 35,868 | $135.6K | 0.00% | +20,470+132.9% | Added |
| Tower Research Capital LLC (TRC) | 45,987 | $173.8K | 0.00% | +36,347+377.0% | Added |
| Jefferies Financial Group Inc. | 46,200 | $174.6K | 0.00% | 00.0% | Unchanged |
| Landscape Capital Management, L.L.C. | 49,661 | $187.7K | 0.02% | +49,661 | New |
| Group One Trading, L.P. | 49,899 | $188.6K | 0.01% | −79,391−61.4% | Reduced |
| Balyasny Asset Management LLC | 50,248 | $189.9K | 0.00% | −655−1.3% | Reduced |
| Ameriprise Financial Inc | 50,428 | $190.6K | 0.00% | +50,428 | New |
| Mariner, LLC | 50,539 | $191.0K | 0.00% | −5,795−10.3% | Reduced |
| XTX Topco Ltd | 53,376 | $201.8K | 0.02% | +5,704+12.0% | Added |
| Dimensional Fund Advisors LP | 54,114 | $204.6K | 0.00% | +54,114 | New |
| Alps Advisors Inc | 55,430 | $209.5K | 0.00% | +55,430 | New |
| JPMorgan Chase & Co | 55,606 | $210.2K | 0.00% | −84,953−60.4% | Reduced |
| Price T Rowe Associates Inc | 57,700 | $219.0K | 0.00% | +2,100+3.8% | Added |
| American Century Companies Inc | 59,310 | $224.2K | 0.00% | +38,261+181.8% | Added |
| Omers Administration Corp | 66,000 | $249.5K | 0.00% | +66,000 | New |
| Point72 Asia (Singapore) Pte. Ltd. | 72,863 | $275.4K | 0.07% | −10,700−12.8% | Reduced |
| Barclays PLC | 74,845 | $282.9K | 0.00% | −9,727−11.5% | Reduced |
| Squarepoint Ops LLC | 75,284 | $284.6K | 0.00% | +27,279+56.8% | Added |
| Boothbay Fund Management, LLC | 80,543 | $304.5K | 0.01% | −4,934−5.8% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 90,619 | $342.5K | 0.02% | −23,915−20.9% | Reduced |
| Tang Capital Management LLC | 100,000 | $378.0K | 0.03% | 00.0% | Unchanged |
| Man Group plc | 100,059 | $378.2K | 0.00% | −30,803−23.5% | Reduced |
| Jump Financial, LLC | 104,342 | $394.4K | 0.01% | +104,342 | New |
| ExodusPoint Capital Management, LP | 106,237 | $402.0K | 0.00% | +106,237 | New |
| Northern Trust Corp | 106,564 | $402.8K | 0.00% | +11,214+11.8% | Added |
| Mackenzie Financial Corp | 111,310 | $420.8K | 0.00% | +78,070+234.9% | Added |
| Kennondale Capital Management LLC | 134,445 | $508.2K | 0.55% | +134,445 | New |
| Bank of Montreal | 143,512 | $542.5K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 146,500 | $553.8K | 0.01% | +16,500+12.7% | Added |
| Falcon Edge Capital, LP | 148,627 | $561.8K | 0.26% | −520,860−77.8% | Reduced |
| Marshall Wace, LLP | 184,678 | $698.1K | 0.00% | −99,308−35.0% | Reduced |
| AQR Capital Management LLC | 188,386 | $712.1K | 0.00% | −460,693−71.0% | Reduced |
| Schonfeld Strategic Advisors LLC | 193,931 | $733.1K | 0.00% | +27,502+16.5% | Added |
| Ikarian Capital, LLC | 201,187 | $760.5K | 0.22% | −73,364−26.7% | Reduced |
| Federated Hermes, Inc. | 202,316 | $764.8K | 0.00% | +16,030+8.6% | Added |
| Wellington Management Group LLP | 209,708 | $792.7K | 0.00% | +209,708 | New |
| State Street Corp | 218,383 | $825.5K | 0.00% | +63,475+41.0% | Added |
| Two Sigma Advisers, LP | 241,400 | $912.5K | 0.00% | −68,100−22.0% | Reduced |
| Aldebaran Capital, LLC | 262,753 | $993.2K | 0.94% | −7,050−2.6% | Reduced |
| Charles Schwab Investment Management Inc | 298,949 | $1.13M | 0.00% | −3,321−1.1% | Reduced |
| D. E. Shaw & Co., Inc. | 306,744 | $1.16M | 0.00% | −384,322−55.6% | Reduced |
| Jacobs Levy Equity Management, Inc | 314,939 | $1.19M | 0.00% | −163,501−34.2% | Reduced |
| OrbiMed Advisors LLC | 348,000 | $1.32M | 0.03% | +348,000 | New |
| Morgan Stanley | 464,220 | $1.75M | 0.00% | −14,045−2.9% | Reduced |
| Renaissance Technologies LLC | 464,400 | $1.76M | 0.00% | +192,600+70.9% | Added |
| Cubist Systematic Strategies, LLC | 472,397 | $1.79M | 0.03% | +423,316+862.5% | Added |
| Walleye Capital LLC | 518,784 | $1.96M | 0.02% | −151,810−22.6% | Reduced |
| Geode Capital Management, LLC | 567,903 | $2.15M | 0.00% | +16,864+3.1% | Added |
| Deutsche Bank AG | 570,857 | $2.16M | 0.00% | 00.0% | Unchanged |
| Millennium Management LLC | 594,236 | $2.25M | 0.00% | +137,420+30.1% | Added |
| Citigroup Inc | 609,324 | $2.30M | 0.00% | +34,319+6.0% | Added |