Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 143
- −35 vs. Q4 2023
- Shares held
- 49.5M
- −10.8M (−17.9%) vs. Q4 2023
- Total value
- $141.5M
- −$745.9M (−84.1%) vs. Q4 2023
- New holders
- 25
- 56 more added
- Sold out
- 60
- 48 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Group One Trading, L.P. | 222,722 | $632.5K | 0.02% | −280,950−55.8% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 23,842 | $671.7K | 0.00% | −515−2.1% | Reduced |
| Susquehanna International Group, LLP | 246,799 | $700.9K | 0.00% | −316,141−56.2% | Reduced |
| Sphera Funds Management Ltd. | 267,250 | $759.0K | 0.12% | +83,600+45.5% | Added |
| Bank of America Corp | 275,956 | $783.7K | 0.00% | +155,628+129.3% | Added |
| Sherbrooke Park Advisers LLC | 299,452 | $850.4K | 0.17% | +299,452 | New |
| Perceptive Advisors LLC | 300,000 | $852.0K | 0.02% | −1,569,125−83.9% | Reduced |
| Sofinnova Investments, Inc. | 306,729 | $871.1K | 0.05% | +306,729 | New |
| Ikarian Capital, LLC | 331,451 | $941.3K | 0.26% | −546,049−62.2% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 341,517 | $969.9K | 0.07% | +292,313+594.1% | Added |
| State of Wisconsin Investment Board | 361,722 | $1.03M | 0.00% | +333,268+1,171.3% | Added |
| Walleye Capital LLC | 361,870 | $1.03M | 0.01% | −220,858−37.9% | Reduced |
| American Century Companies Inc | 378,798 | $1.08M | 0.00% | −163,748−30.2% | Reduced |
| JPMorgan Chase & Co | 409,759 | $1.16M | 0.00% | +337,871+470.0% | Added |
| Northern Trust Corp | 425,567 | $1.21M | 0.00% | −9,870−2.3% | Reduced |
| Charles Schwab Investment Management Inc | 435,903 | $1.24M | 0.00% | +48,283+12.5% | Added |
| Hudson Bay Capital Management LP | 498,000 | $1.41M | 0.01% | +37,400+8.1% | Added |
| Silverarc Capital Management, LLC | 500,000 | $1.42M | 0.40% | +500,000 | New |
| Woodline Partners LP | 523,772 | $1.49M | 0.01% | +52,971+11.3% | Added |
| Graham Capital Management, L.P. | 524,627 | $1.49M | 0.04% | +524,627 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 526,688 | $1.50M | 0.01% | +270,082+105.3% | Added |
| Renaissance Technologies LLC | 704,600 | $2.00M | 0.00% | +633,312+888.4% | Added |
| Deutsche Bank AG | 756,169 | $2.15M | 0.00% | −96,831−11.4% | Reduced |
| Two Sigma Advisers, LP | 798,900 | $2.27M | 0.01% | +798,900 | New |
| Citigroup Inc | 914,727 | $2.60M | 0.00% | +527,063+136.0% | Added |
| Qube Research & Technologies Ltd | 944,063 | $2.68M | 0.00% | +461,464+95.6% | Added |
| Price T Rowe Associates Inc | 970,555 | $2.76M | 0.00% | +75,775+8.5% | Added |
| Alyeska Investment Group, L.P. | 1,008,607 | $2.86M | 0.02% | +1,008,607 | New |
| Rock Springs Capital Management LP | 1,011,412 | $2.87M | 0.07% | +476,400+89.0% | Added |
| Jane Street Group, LLC | 1,027,620 | $2.92M | 0.00% | −129,545−11.2% | Reduced |
| D. E. Shaw & Co., Inc. | 1,042,583 | $2.96M | 0.00% | +495,618+90.6% | Added |
| Geode Capital Management, LLC | 1,066,245 | $3.03M | 0.00% | +35,529+3.4% | Added |
| Farallon Capital Management, L.L.C. | 1,150,221 | $3.27M | 0.02% | +1,150,221 | New |
| Citadel Advisors LLC | 1,330,384 | $3.78M | 0.00% | −910,501−40.6% | Reduced |
| Two Sigma Investments, LP | 1,432,865 | $4.07M | 0.01% | +1,389,065+3,171.4% | Added |
| Boxer Capital, LLC | 1,500,000 | $4.26M | 0.21% | +1,500,000 | New |
| Franklin Resources Inc | 1,855,886 | $5.27M | 0.00% | +530,885+40.1% | Added |
| State Street Corp | 2,060,042 | $5.85M | 0.00% | +618,640+42.9% | Added |
| Morgan Stanley | 2,070,653 | $5.88M | 0.00% | −759,590−26.8% | Reduced |
| Millennium Management LLC | 2,471,455 | $7.02M | 0.01% | +198,812+8.7% | Added |
| Goldman Sachs Group Inc | 2,943,186 | $8.36M | 0.00% | +1,686,325+134.2% | Added |
| BlackRock Inc. | 4,474,722 | $12.7M | 0.00% | +472,388+11.8% | Added |
| Vanguard Group Inc | 5,348,139 | $15.2M | 0.00% | +72,573+1.4% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 0 | $0 | 0.00% | −2,962,555−100.0% | Sold out |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −2,500,000−100.0% | Sold out |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −1,116,837−100.0% | Sold out |
| Saturn V Capital Management LLC | 0 | $0 | 0.00% | −1,099,268−100.0% | Sold out |
| Jupiter Asset Management Ltd | 0 | $0 | 0.00% | −1,060,900−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −985,114−100.0% | Sold out |
| Falcon Edge Capital, LP | 0 | $0 | 0.00% | −846,240−100.0% | Sold out |
| Emerald Advisers, LLC | 0 | $0 | 0.00% | −802,610−100.0% | Sold out |
| GMT Capital Corp | 0 | $0 | 0.00% | −786,000−100.0% | Sold out |
| Emerald Mutual Fund Advisers Trust | 0 | $0 | 0.00% | −656,530−100.0% | Sold out |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −620,110−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −465,445−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −312,463−100.0% | Sold out |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −295,000−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −275,773−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −265,046−100.0% | Sold out |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −242,300−100.0% | Sold out |
| AlphaCentric Advisors LLC | 0 | $0 | 0.00% | −151,000−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −147,020−100.0% | Sold out |
| DAFNA Capital Management LLC | 0 | $0 | 0.00% | −122,547−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −119,526−100.0% | Sold out |
| Norges Bank | 0 | $0 | 0.00% | −116,400−100.0% | Sold out |
| Phocas Financial Corp. | 0 | $0 | 0.00% | −86,073−100.0% | Sold out |
| Sectoral Asset Management Inc | 0 | $0 | 0.00% | −84,055−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −83,381−100.0% | Sold out |
| DekaBank Deutsche Girozentrale | 0 | $0 | 0.00% | −83,000−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −72,824−100.0% | Sold out |
| Seven Eight Capital, LP | 0 | $0 | 0.00% | −66,801−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −64,501−100.0% | Sold out |
| Janney Montgomery Scott LLC | 0 | $0 | 0.00% | −59,111−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −57,850−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −53,517−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −47,000−100.0% | Sold out |
| Cornercap Investment Counsel Inc | 0 | $0 | 0.00% | −44,487−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −42,192−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −35,774−100.0% | Sold out |
| Landscape Capital Management, L.L.C. | 0 | $0 | 0.00% | −33,689−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −31,342−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −29,205−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −27,715−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −26,349−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −22,007−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −19,698−100.0% | Sold out |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −19,561−100.0% | Sold out |
| Centiva Capital, LP | 0 | $0 | 0.00% | −19,188−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −19,029−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −18,913−100.0% | Sold out |
| Greenwood Capital Associates LLC | 0 | $0 | 0.00% | −17,395−100.0% | Sold out |
| Lion Point Capital, LP | 0 | $0 | 0.00% | −14,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −13,343−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −13,213−100.0% | Sold out |
| Integrated Wealth Concepts LLC | 0 | $0 | 0.00% | −10,641−100.0% | Sold out |
| Point72 Middle East FZE | 0 | $0 | 0.00% | −9,141−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −6,035−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −5,100−100.0% | Sold out |
| Capital Advisors, Ltd. LLC | 0 | $0 | 0.00% | −290−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −200−100.0% | Sold out |