Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 147
- +14 vs. Q4 2022
- Shares held
- 51.4M
- +2.80M (+5.8%) vs. Q4 2022
- Total value
- $1.51B
- −$286.0M (−15.9%) vs. Q4 2022
- New holders
- 38
- 60 more added
- Sold out
- 24
- 36 more reduced
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Voloridge Investment Management, LLC | 135,465 | $3.97M | 0.02% | −159,802−54.1% | Reduced |
| Polar Asset Management Partners Inc. | 177,200 | $5.20M | 0.09% | +177,200 | New |
| Altium Capital Management LP | 185,000 | $5.43M | 3.24% | +45,000+32.1% | Added |
| Bank of New York Mellon Corp | 204,656 | $6.00M | 0.00% | −5,483−2.6% | Reduced |
| Ameriprise Financial Inc | 212,453 | $6.23M | 0.00% | +8,377+4.1% | Added |
| Verition Fund Management LLC | 221,598 | $6.50M | 0.10% | −38,953−15.0% | Reduced |
| Citadel Advisors LLC | 228,906 | $6.72M | 0.01% | +172,149+303.3% | Added |
| Sectoral Asset Management Inc | 242,400 | $7.11M | 1.37% | +84,450+53.5% | Added |
| Lord, Abbett & Co. LLC | 250,042 | $7.34M | 0.03% | +250,042 | New |
| Alyeska Investment Group, L.P. | 251,407 | $7.38M | 0.07% | +201,407+402.8% | Added |
| Jane Street Group, LLC | 264,858 | $7.77M | 0.01% | +128,301+94.0% | Added |
| Allspring Global Investments Holdings, LLC | 277,788 | $8.15M | 0.01% | +11,769+4.4% | Added |
| Schonfeld Strategic Advisors LLC | 285,005 | $8.36M | 0.08% | +173,081+154.6% | Added |
| Charles Schwab Investment Management Inc | 320,086 | $9.39M | 0.00% | +2,367+0.7% | Added |
| Point72 Asset Management, L.P. | 324,800 | $9.53M | 0.03% | −1,803,160−84.7% | Reduced |
| ExodusPoint Capital Management, LP | 393,904 | $11.6M | 0.13% | +189,967+93.1% | Added |
| Balyasny Asset Management LLC | 420,841 | $12.3M | 0.04% | −224,712−34.8% | Reduced |
| Woodline Partners LP | 434,200 | $12.7M | 0.18% | −74,153−14.6% | Reduced |
| Eventide Asset Management, LLC | 458,054 | $13.4M | 0.25% | +208,054+83.2% | Added |
| Northern Trust Corp | 463,880 | $13.6M | 0.00% | +68,741+17.4% | Added |
| Avoro Capital Advisors LLC | 473,100 | $13.9M | 0.21% | −156,900−24.9% | Reduced |
| Ghost Tree Capital, LLC | 475,000 | $13.9M | 5.27% | +125,000+35.7% | Added |
| Nuveen Asset Management, LLC | 611,932 | $18.0M | 0.01% | +15,878+2.7% | Added |
| Voya Investment Management LLC | 619,030 | $18.2M | 0.02% | +576,884+1,368.8% | Added |
| Great Point Partners LLC | 783,795 | $23.0M | 4.55% | +593,795+312.5% | Added |
| Emerald Mutual Fund Advisers Trust | 789,591 | $23.2M | 1.37% | +134,576+20.5% | Added |
| OrbiMed Advisors LLC | 813,500 | $23.9M | 0.47% | +813,500 | New |
| Geode Capital Management, LLC | 890,982 | $26.1M | 0.00% | +37,069+4.3% | Added |
| Avidity Partners Management LP | 900,000 | $26.4M | 0.88% | +900,000 | New |
| Morgan Stanley | 902,547 | $26.5M | 0.00% | +418,078+86.3% | Added |
| Falcon Edge Capital, LP | 930,337 | $27.3M | 10.08% | +109,117+13.3% | Added |
| Emerald Advisers, LLC | 972,835 | $28.5M | 1.37% | +135,926+16.2% | Added |
| Adage Capital Partners GP, L.L.C. | 1,007,336 | $29.6M | 0.07% | −901,865−47.2% | Reduced |
| State Street Corp | 1,066,238 | $31.3M | 0.00% | −9,374−0.9% | Reduced |
| Millennium Management LLC | 1,074,610 | $31.5M | 0.04% | +215,195+25.0% | Added |
| Marshall Wace, LLP | 1,139,240 | $33.4M | 0.08% | +1,139,240 | New |
| Goldman Sachs Group Inc | 1,366,172 | $40.1M | 0.01% | +329,902+31.8% | Added |
| Pictet Asset Management SA | 1,433,846 | $42.1M | 0.05% | +312,081+27.8% | Added |
| Rock Springs Capital Management LP | 1,452,816 | $42.6M | 1.02% | +223,179+18.1% | Added |
| Federated Hermes, Inc. | 1,846,117 | $54.2M | 0.14% | +231,272+14.3% | Added |
| Deerfield Management Company, L.P. (Series C) | 1,984,333 | $58.2M | 1.30% | −708,667−26.3% | Reduced |
| D. E. Shaw & Co., Inc. | 2,022,370 | $59.3M | 0.10% | +638,638+46.2% | Added |
| Boxer Capital, LLC | 2,084,000 | $61.1M | 3.00% | 00.0% | Unchanged |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $86.9M | 0.41% | −1,672,051−36.1% | Reduced |
| BlackRock Inc. | 3,614,918 | $106.1M | 0.00% | −2,008−0.1% | Reduced |
| Vanguard Group Inc | 4,747,341 | $139.3M | 0.00% | +388,849+8.9% | Added |
| Perceptive Advisors LLC | 6,034,644 | $177.1M | 5.24% | −53,689−0.9% | Reduced |
| Cormorant Asset Management, LP | 0 | $0 | 0.00% | −550,000−100.0% | Sold out |
| Iron Triangle Partners LP | 0 | $0 | 0.00% | −240,240−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −178,300−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −65,272−100.0% | Sold out |
| EAM Global Investors LLC | 0 | $0 | 0.00% | −45,750−100.0% | Sold out |
| Prescott Group Capital Management, L.L.C. | 0 | $0 | 0.00% | −40,000−100.0% | Sold out |
| Moody Aldrich Partners LLC | 0 | $0 | 0.00% | −38,064−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −24,248−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −17,492−100.0% | Sold out |
| Oversea-Chinese Banking CORP Ltd | 0 | $0 | 0.00% | −16,785−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −12,936−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −10,092−100.0% | Sold out |
| Cheyne Capital Management (UK) LLP | 0 | $0 | 0.00% | −9,499−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −7,642−100.0% | Sold out |
| Raymond James Financial Services Advisors, Inc. | 0 | $0 | 0.00% | −6,773−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −6,298−100.0% | Sold out |
| Handelsbanken Fonder AB | 0 | $0 | 0.00% | −6,100−100.0% | Sold out |
| Cutler Group LP | 0 | $0 | 0.00% | −3,200−100.0% | Sold out |
| High Net Worth Advisory Group LLC | 0 | $0 | 0.00% | −3,000−100.0% | Sold out |
| DuPont Capital Management Corp | 0 | $0 | 0.00% | −2,902−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −2,460−100.0% | Sold out |
| CIBC Private Wealth Group, LLC | 0 | $0 | 0.00% | −41,476−100.0% | Sold out |
| Credit Suisse AG | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Capital Advisors, Ltd. LLC | 0 | $0 | 0.00% | −290−100.0% | Sold out |