Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 133
- +39 vs. Q3 2022
- Shares held
- 48.6M
- +11.3M (+30.3%) vs. Q3 2022
- Total value
- $1.79B
- +$748.1M (+71.6%) vs. Q3 2022
- New holders
- 47
- 49 more added
- Sold out
- 8
- 32 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Iron Triangle Partners LP | 240,240 | $8.88M | 1.59% | +240,240 | New |
| Eventide Asset Management, LLC | 250,000 | $9.24M | 0.18% | +250,000 | New |
| Verition Fund Management LLC | 260,551 | $9.63M | 0.19% | −51,865−16.6% | Reduced |
| Allspring Global Investments Holdings, LLC | 266,019 | $9.83M | 0.02% | −3,479−1.3% | Reduced |
| Voloridge Investment Management, LLC | 295,267 | $10.9M | 0.06% | −86,945−22.7% | Reduced |
| Charles Schwab Investment Management Inc | 317,719 | $11.7M | 0.00% | +76,980+32.0% | Added |
| Ghost Tree Capital, LLC | 350,000 | $12.9M | 5.52% | −200,000−36.4% | Reduced |
| Northern Trust Corp | 395,139 | $14.6M | 0.00% | +109,331+38.3% | Added |
| Morgan Stanley | 484,469 | $17.9M | 0.00% | +215,399+80.1% | Added |
| Woodline Partners LP | 508,353 | $18.8M | 0.26% | −512,031−50.2% | Reduced |
| Cormorant Asset Management, LP | 550,000 | $20.3M | 1.37% | −60,000−9.8% | Reduced |
| Nuveen Asset Management, LLC | 596,054 | $22.0M | 0.01% | +239,367+67.1% | Added |
| Avoro Capital Advisors LLC | 630,000 | $23.3M | 0.35% | −20,000−3.1% | Reduced |
| Balyasny Asset Management LLC | 645,553 | $23.9M | 0.08% | +454,219+237.4% | Added |
| Emerald Mutual Fund Advisers Trust | 655,015 | $24.2M | 1.50% | +183,128+38.8% | Added |
| Falcon Edge Capital, LP | 821,220 | $30.3M | 5.54% | +120,585+17.2% | Added |
| Emerald Advisers, LLC | 836,909 | $30.9M | 1.49% | +235,683+39.2% | Added |
| Geode Capital Management, LLC | 853,913 | $31.6M | 0.00% | +218,357+34.4% | Added |
| Millennium Management LLC | 859,415 | $31.8M | 0.04% | −61,713−6.7% | Reduced |
| Goldman Sachs Group Inc | 1,036,270 | $38.3M | 0.01% | +656,871+173.1% | Added |
| State Street Corp | 1,075,612 | $39.7M | 0.00% | +248,544+30.1% | Added |
| Pictet Asset Management SA | 1,121,765 | $41.4M | 0.06% | +1,121,765 | New |
| Rock Springs Capital Management LP | 1,229,637 | $45.4M | 1.09% | +825,900+204.6% | Added |
| D. E. Shaw & Co., Inc. | 1,383,732 | $51.1M | 0.09% | +1,221,467+752.8% | Added |
| Federated Hermes, Inc. | 1,614,845 | $59.7M | 0.17% | +285,845+21.5% | Added |
| Adage Capital Partners GP, L.L.C. | 1,909,201 | $70.5M | 0.17% | +559,201+41.4% | Added |
| Boxer Capital, LLC | 2,084,000 | $77.0M | 4.14% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 2,127,960 | $78.6M | 0.30% | +1,660,999+355.7% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,693,000 | $99.5M | 2.06% | +2,693,000 | New |
| BlackRock Inc. | 3,616,926 | $133.6M | 0.00% | +1,321,092+57.5% | Added |
| Vanguard Group Inc | 4,358,492 | $161.0M | 0.00% | +844,136+24.0% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 4,634,606 | $171.2M | 0.86% | −1,135,930−19.7% | Reduced |
| Perceptive Advisors LLC | 6,088,333 | $225.0M | 6.48% | +616,300+11.3% | Added |
| Bain Capital Life Sciences Investors, LLC | 0 | $0 | 0.00% | −1,023,214−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −341,064−100.0% | Sold out |
| Pura Vida Investments, LLC | 0 | $0 | 0.00% | −68,652−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −42,947−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −10,285−100.0% | Sold out |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 0 | $0 | 0.00% | −1,803−100.0% | Sold out |
| Cowen and Company, LLC | 0 | $0 | 0.00% | −20,800−100.0% | Sold out |
| Ronald Blue Trust, Inc. | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Jefferies Group LLC | – | – | – | – | Not filed |