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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
133
+39 vs. Q3 2022
Shares held
48.6M
+11.3M (+30.3%) vs. Q3 2022
Total value
$1.79B
+$748.1M (+71.6%) vs. Q3 2022
New holders
47
49 more added
Sold out
8
32 more reduced

1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 133 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ4 2022: $1.79B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding AMLX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd4$00.00%−1−20.0%Reduced
Capital Advisors, Ltd. LLC290$00.00%+290New
Credit Suisse AG2$740.00%−195−99.0%Reduced
Dark Forest Capital Management LP10$3700.00%+10New
Nisa Investment Advisors, LLC26$1.00K0.00%00.0%Unchanged
Kelly Financial Services LLC33$1.22K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC41,476$1.53K0.00%+41,476New
Credit Agricole S A200$7.39K0.00%−300−60.0%Reduced
Daiwa Securities Group Inc.266$10.0K0.00%+266New
Connective Capital Management, LLC466$17.2K0.01%+466New
Tradition Wealth Management, LLC500$18.0K0.00%00.0%Unchanged
Advisory Services Network, LLC500$18.5K0.00%+500New
China Universal Asset Management Co., Ltd.673$24.9K0.01%+673New
Steward Partners Investment Advisory, LLC1,100$40.6K0.00%+50+4.8%Added
Advisor Group Holdings, Inc.1,375$51.0K0.00%−1,067−43.7%Reduced
Wells Fargo & Company1,719$63.5K0.00%+762+79.6%Added
Tower Research Capital LLC (TRC)1,898$70.0K0.00%−1,160−37.9%Reduced
Walleye Trading LLC2,460$90.9K0.00%+2,460New
DuPont Capital Management Corp2,902$107.2K0.01%+2,902New
High Net Worth Advisory Group LLC3,000$110.8K0.04%+1,000+50.0%Added
Metropolitan Life Insurance Co3,150$116.4K0.01%+943+42.7%Added
Cutler Group LP3,200$118.0K0.01%−8,325−72.2%Reduced
UBS Group AG3,477$128.5K0.00%−510−12.8%Reduced
Cubist Systematic Strategies, LLC3,806$140.6K0.00%−298−7.3%Reduced
Advisors Asset Management, Inc.3,905$144.3K0.00%+3,905New
Ameritas Investment Partners, Inc.4,035$152.9K0.01%+1,271+46.0%Added
STRS Ohio4,500$166.0K0.00%+3,300+275.0%Added
Legal & General Group Plc5,023$185.6K0.00%+1,562+45.1%Added
Handelsbanken Fonder AB6,100$225.0K0.00%+6,100New
Rafferty Asset Management, LLC6,298$232.7K0.00%+6,298New
Royal Bank of Canada6,677$247.0K0.00%+5,304+386.3%Added
Raymond James Financial Services Advisors, Inc.6,773$250.3K0.00%+6,773New
US Bancorp6,995$258.5K0.00%+6,995New
Amalgamated Bank7,025$260.0K0.00%+2,247+47.0%Added
Belvedere Trading LLC7,642$282.4K0.16%−35,857−82.4%Reduced
FMR LLC7,804$288.4K0.00%+7,468+2,222.6%Added
Virtus ETF Advisers LLC8,307$306.9K0.16%+8,307New
State Board of Administration of Florida Retirement System8,310$307.1K0.00%+8,310New
Cheyne Capital Management (UK) LLP9,499$351.0K0.62%+9,499New
Citigroup Inc9,723$359.3K0.00%+1,002+11.5%Added
Fred Alger Management, LLC10,092$372.9K0.00%−2,750−21.4%Reduced
SG Americas Securities, LLC10,489$388.0K0.01%+10,489New
ProShare Advisors LLC11,968$442.2K0.00%+11,968New
Integrated Wealth Concepts LLC12,368$457.0K0.01%+12,368New
Kestra Advisory Services, LLC12,936$478.0K0.00%−29,747−69.7%Reduced
Principal Financial Group Inc13,513$499.3K0.00%+13,513New
SEI Investments Co13,777$509.1K0.00%−49,897−78.4%Reduced
Bayesian Capital Management, LP14,700$543.2K0.08%+14,700New
Seven Eight Capital, LP14,938$552.0K0.14%+2,876+23.8%Added
Price T Rowe Associates Inc15,683$579.0K0.00%+15,683New
Oversea-Chinese Banking CORP Ltd16,785$620.0K0.04%+16,785New
Hennion & Walsh Asset Management, Inc.16,956$627.0K0.04%+16,956New
Walleye Capital LLC17,492$646.3K0.01%−44,390−71.7%Reduced
California State Teachers Retirement System20,131$743.8K0.00%+6,208+44.6%Added
Manufacturers Life Insurance Company, The20,136$744.0K0.00%+20,136New
Deutsche Bank AG21,961$811.5K0.00%+6,977+46.6%Added
Putnam Investments LLC23,032$851.0K0.00%−13−0.1%Reduced
Mirae Asset Global Investments Co., Ltd.23,507$868.6K0.00%+8,622+57.9%Added
American International Group, Inc.23,853$881.4K0.01%+7,117+42.5%Added
Artia Global Partners LP23,883$882.5K0.34%+23,883New
Simplex Trading, LLC24,248$895.0K0.04%−92,356−79.2%Reduced
Group One Trading, L.P.25,538$943.6K0.03%−63,447−71.3%Reduced
MetLife Investment Management26,712$987.0K0.01%+7,251+37.3%Added
Parsons Capital Management Inc27,145$1.00M0.08%+10,280+61.0%Added
Brown Advisory Inc33,441$1.24M0.00%−10,000−23.0%Reduced
New York State Common Retirement Fund33,703$1.25M0.00%+10,297+44.0%Added
Pentwater Capital Management LP35,000$1.29M0.04%+35,000New
Tudor Investment Corp Et Al35,997$1.33M0.03%+19,859+123.1%Added
Alliancebernstein L.P.36,242$1.34M0.00%00.0%Unchanged
Mariner, LLC37,991$1.40M0.00%+37,991New
Moody Aldrich Partners LLC38,064$1.41M0.28%+38,064New
Barclays PLC38,495$1.42M0.00%+19,695+104.8%Added
Squarepoint Ops LLC40,000$1.48M0.01%−1,792−4.3%Reduced
Prescott Group Capital Management, L.L.C.40,000$1.48M0.32%+4,996+14.3%Added
Voya Investment Management LLC42,146$1.56M0.00%+28,611+211.4%Added
Alps Advisors Inc44,912$1.66M0.01%+44,912New
J. Goldman & Co LP45,642$1.69M0.12%+45,642New
EAM Global Investors LLC45,750$1.69M0.44%+45,750New
JPMorgan Chase & Co49,701$1.84M0.00%+30,437+158.0%Added
Alyeska Investment Group, L.P.50,000$1.85M0.02%+50,000New
Soleus Capital Management, L.P.50,636$1.87M0.27%−378,700−88.2%Reduced
Citadel Advisors LLC56,757$2.10M0.00%−750,073−93.0%Reduced
First Trust Advisors LP56,820$2.10M0.00%+56,820New
Bank of America Corp63,366$2.34M0.00%+54,479+613.0%Added
EAM Investors, LLC65,272$2.41M0.50%+65,272New
Wellington Management Group LLP67,905$2.51M0.00%+67,905New
Rhumbline Advisers71,564$2.64M0.00%+25,771+56.3%Added
Norges Bank81,200$3.00M0.00%+81,200New
Tang Capital Management LLC100,000$3.69M0.54%+100,000New
Schonfeld Strategic Advisors LLC111,924$4.14M0.03%−213,776−65.6%Reduced
Jane Street Group, LLC136,557$5.05M0.01%+136,557New
Altium Capital Management LP140,000$5.17M2.65%+105,000+300.0%Added
Maven Securities LTD150,000$5.54M1.11%+150,000New
Sectoral Asset Management Inc157,950$5.84M1.13%−47,450−23.1%Reduced
Renaissance Technologies LLC178,300$6.59M0.01%+178,300New
Great Point Partners LLC190,000$7.02M1.45%+190,000New
ExodusPoint Capital Management, LP203,937$7.54M0.12%+141,718+227.8%Added
Ameriprise Financial Inc204,076$7.54M0.00%+136,201+200.7%Added
Bank of New York Mellon Corp210,139$7.76M0.00%+93,195+79.7%Added
Invesco Ltd.215,470$7.96M0.00%−46,066−17.6%Reduced