Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、6 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2024 年第 4 季 13F 持有人
Spyre Therapeutics, Inc. 在 2024/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 131
- 較 2024 年第 3 季 +13 家
- 持有股數
- 5,988 萬
- 較 2024 年第 3 季 +856.9 萬 (+16.7%)
- 總市值
- $13.9 億
- 較 2024 年第 3 季 −$1.16 億 (−7.7%)
- 新進機構
- 34
- 另有 63 家加碼
- 清倉機構
- 21
- 另有 20 家減碼
另有 1 家機構在 2024 年第 3 季持有、還沒有申報 2024 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2024 年第 4 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2024 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| CWM, LLC | 8 | $0 | 0.00% | −219−96.5% | 減碼 |
| Covestor Ltd | 4 | $0 | 0.00% | +1+33.3% | 加碼 |
| SBI Securities Co., Ltd. | 5 | $116 | 0.00% | +5 | 新進 |
| Pacific Capital Wealth Advisors, Inc | 8 | $186 | 0.00% | 00.0% | 不變 |
| EverSource Wealth Advisors, LLC | 8 | $186 | 0.00% | +8 | 新進 |
| Allworth Financial LP | 9 | $197 | 0.00% | +2+28.6% | 加碼 |
| Caitong International Asset Management Co., Ltd | 14 | $326 | 0.00% | +14 | 新進 |
| Amundi | 32 | $769 | 0.00% | +32 | 新進 |
| Rothschild Investment LLC | 40 | $931 | 0.00% | 00.0% | 不變 |
| Simplex Trading, LLC | 55 | $1,000 | 0.00% | +55 | 新進 |
| Signaturefd, LLC | 68 | $1,583 | 0.00% | +68 | 新進 |
| Advisor Group Holdings, Inc. | 105 | $2,443 | 0.00% | +22+26.5% | 加碼 |
| IFP Advisors, Inc | 109 | $2,770 | 0.00% | −5−4.4% | 減碼 |
| Nisa Investment Advisors, LLC | 120 | $2,794 | 0.00% | +9+8.1% | 加碼 |
| Skopos Labs, Inc. | 120 | $2,794 | 0.00% | +120 | 新進 |
| Sugar Maple Asset Management, LLC | 180 | $4,190 | 0.00% | +180 | 新進 |
| Venturi Wealth Management, LLC | 231 | $5,378 | 0.00% | +231 | 新進 |
| R Squared Ltd | 710 | $1.65 萬 | 0.02% | +710 | 新進 |
| Sterling Capital Management LLC | 1,009 | $2.35 萬 | 0.00% | +894+777.4% | 加碼 |
| Amalgamated Bank | 1,198 | $2.80 萬 | 0.00% | 00.0% | 不變 |
| GF Fund Management Co. Ltd. | 1,232 | $2.87 萬 | 0.00% | +1,232 | 新進 |
| Huntington National Bank | 1,470 | $3.42 萬 | 0.00% | +1,470 | 新進 |
| Public Employees Retirement Association of Colorado | 1,589 | $3.70 萬 | 0.00% | 00.0% | 不變 |
| Mirae Asset Global Investments Co., Ltd. | 1,955 | $4.63 萬 | 0.00% | +1,955 | 新進 |
| Quest Partners LLC | 2,198 | $5.12 萬 | 0.01% | −3,456−61.1% | 減碼 |
| Virtus ETF Advisers LLC | 2,972 | $6.92 萬 | 0.03% | +124+4.4% | 加碼 |
| Ameritas Investment Partners, Inc. | 3,392 | $7.90 萬 | 0.00% | 00.0% | 不變 |
| Royal Bank of Canada | 4,022 | $9.40 萬 | 0.00% | +236+6.2% | 加碼 |
| Bank of America Corp | 7,142 | $16.6 萬 | 0.00% | −250,655−97.2% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 7,378 | $17.2 萬 | 0.00% | +7,378 | 新進 |
| KLP Kapitalforvaltning AS | 7,800 | $18.2 萬 | 0.00% | +7,800 | 新進 |
| Tower Research Capital LLC (TRC) | 8,574 | $20.0 萬 | 0.00% | +8,054+1,548.8% | 加碼 |
| State Board of Administration of Florida Retirement System | 9,030 | $21.0 萬 | 0.00% | 00.0% | 不變 |
| Carlyle Group Inc. | 9,620 | $22.4 萬 | 0.01% | 00.0% | 不變 |
| Two Sigma Investments, LP | 9,638 | $22.4 萬 | 0.00% | −165−1.7% | 減碼 |
| Arizona State Retirement System | 10,115 | $23.5 萬 | 0.00% | +2,805+38.4% | 加碼 |
| New York State Common Retirement Fund | 10,265 | $23.9 萬 | 0.00% | 00.0% | 不變 |
| Teacher Retirement System of Texas | 10,383 | $24.2 萬 | 0.00% | +10,383 | 新進 |
| Voya Investment Management LLC | 10,495 | $24.4 萬 | 0.00% | −856−7.5% | 減碼 |
| Aquatic Capital Management LLC | 11,767 | $27.4 萬 | 0.01% | +11,767 | 新進 |
| China Universal Asset Management Co., Ltd. | 12,440 | $29.0 萬 | 0.03% | +12,440 | 新進 |
| ProShare Advisors LLC | 12,531 | $29.2 萬 | 0.00% | +12,531 | 新進 |
| Intech Investment Management LLC | 14,043 | $32.7 萬 | 0.00% | +5,672+67.8% | 加碼 |
| Profund Advisors LLC | 14,862 | $34.6 萬 | 0.01% | +787+5.6% | 加碼 |
| Squarepoint Ops LLC | 15,231 | $35.5 萬 | 0.00% | +6,754+79.7% | 加碼 |
| ExodusPoint Capital Management, LP | 16,691 | $38.9 萬 | 0.00% | +6,958+71.5% | 加碼 |
| Brevan Howard Capital Management LP | 16,899 | $39.3 萬 | 0.01% | +16,899 | 新進 |
| Corebridge Financial, Inc. | 17,213 | $40.1 萬 | 0.00% | −1,299−7.0% | 減碼 |
| Natixis Advisors, L.P. | 17,300 | $40.3 萬 | 0.00% | +17,300 | 新進 |
| Global Endowment Management, LP | 18,184 | $42.3 萬 | 0.05% | 00.0% | 不變 |
| BNP Paribas Arbitrage, SA | 18,784 | $43.7 萬 | 0.00% | +18,784 | 新進 |
| NBW Capital LLC | 19,430 | $45.2 萬 | 0.08% | −7,500−27.8% | 減碼 |
| Cinctive Capital Management LP | 19,567 | $45.6 萬 | 0.02% | −41,689−68.1% | 減碼 |
| Invesco Ltd. | 19,663 | $45.8 萬 | 0.00% | −118,195−85.7% | 減碼 |
| MetLife Investment Management | 21,382 | $49.8 萬 | 0.00% | +1,250+6.2% | 加碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 22,741 | $52.7 萬 | 0.00% | +916+4.2% | 加碼 |
| Assenagon Asset Management S.A. | 22,652 | $52.7 萬 | 0.00% | −1,120,116−98.0% | 減碼 |
| Susquehanna International Group, LLP | 23,089 | $53.8 萬 | 0.00% | +9,891+74.9% | 加碼 |
| First Trust Advisors LP | 23,550 | $54.8 萬 | 0.00% | +23,550 | 新進 |
| Wells Fargo & Company | 24,718 | $57.5 萬 | 0.00% | +6,908+38.8% | 加碼 |
| Teachers Retirement System of the State of Kentucky | 25,799 | $60.1 萬 | 0.01% | +4,645+22.0% | 加碼 |
| Deutsche Bank AG | 31,418 | $73.1 萬 | 0.00% | +9,910+46.1% | 加碼 |
| State of Wisconsin Investment Board | 31,484 | $73.3 萬 | 0.00% | +13,169+71.9% | 加碼 |
| California State Teachers Retirement System | 32,598 | $75.9 萬 | 0.00% | +7,923+32.1% | 加碼 |
| JPMorgan Chase & Co | 35,248 | $82.1 萬 | 0.00% | +5,775+19.6% | 加碼 |
| Alliancebernstein L.P. | 36,230 | $84.3 萬 | 0.00% | 00.0% | 不變 |
| Legal & General Group Plc | 37,490 | $87.3 萬 | 0.00% | +8,335+28.6% | 加碼 |
| F/M Investments LLC | 48,806 | $113.6 萬 | 0.04% | +48,806 | 新進 |
| UBS Asset Management Americas Inc | 48,981 | $114.0 萬 | 0.00% | +22,540+85.2% | 加碼 |
| B Group, Inc. | 50,000 | $116.4 萬 | 0.71% | +50,000 | 新進 |
| Manufacturers Life Insurance Company, The | 52,762 | $122.8 萬 | 0.00% | +9,302+21.4% | 加碼 |
| Rhumbline Advisers | 57,657 | $134.2 萬 | 0.00% | +3,722+6.9% | 加碼 |
| TD Asset Management Inc | 64,968 | $151.2 萬 | 0.00% | +12,200+23.1% | 加碼 |
| Swiss National Bank | 68,600 | $159.7 萬 | 0.00% | +19,000+38.3% | 加碼 |
| Citigroup Inc | 73,752 | $171.7 萬 | 0.00% | +48,561+192.8% | 加碼 |
| Rafferty Asset Management, LLC | 76,740 | $178.7 萬 | 0.01% | +6,154+8.7% | 加碼 |
| Prosight Management, LP | 80,000 | $186.2 萬 | 0.52% | +80,000 | 新進 |
| Ensign Peak Advisors, Inc | 82,475 | $192.0 萬 | 0.00% | 00.0% | 不變 |
| EFG Asset Management (North America) Corp. | 82,818 | $192.9 萬 | 0.26% | +30,608+58.6% | 加碼 |
| Boothbay Fund Management, LLC | 85,618 | $199.3 萬 | 0.06% | −6,157−6.7% | 減碼 |
| HighVista Strategies LLC | 95,159 | $221.5 萬 | 0.82% | −10,192−9.7% | 減碼 |
| Bank of New York Mellon Corp | 103,688 | $241.4 萬 | 0.00% | −1,118−1.1% | 減碼 |
| Schroder Investment Management Group | 113,620 | $256.1 萬 | 0.00% | +113,620 | 新進 |
| Voloridge Investment Management, LLC | 115,470 | $268.8 萬 | 0.01% | −41,011−26.2% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 122,153 | $284.4 萬 | 0.01% | +122,153 | 新進 |
| Barclays PLC | 123,071 | $286.5 萬 | 0.00% | +17,604+16.7% | 加碼 |
| Nuveen Asset Management, LLC | 125,668 | $292.6 萬 | 0.00% | +378+0.3% | 加碼 |
| Millennium Management LLC | 167,804 | $390.6 萬 | 0.00% | +167,804 | 新進 |
| Armistice Capital, LLC | 200,000 | $465.6 萬 | 0.11% | +64,000+47.1% | 加碼 |
| Deep Track Capital, LP | 219,015 | $509.9 萬 | 0.19% | −780,985−78.1% | 減碼 |
| Candriam Luxembourg S.C.A. | 247,591 | $576.4 萬 | 0.03% | +142,591+135.8% | 加碼 |
| Soros Fund Management LLC大師索羅斯基金管理 | 250,000 | $582.0 萬 | 0.10% | +105,000+72.4% | 加碼 |
| Morgan Stanley | 255,256 | $594.2 萬 | 0.00% | +11,514+4.7% | 加碼 |
| Victory Capital Management Inc | 268,076 | $624.1 萬 | 0.01% | +268,076 | 新進 |
| Ikarian Capital, LLC | 282,159 | $656.9 萬 | 1.88% | −20,088−6.6% | 減碼 |
| Northern Trust Corp | 348,983 | $812.4 萬 | 0.00% | +34,693+11.0% | 加碼 |
| Woodline Partners LP | 352,680 | $821.0 萬 | 0.06% | +88,424+33.5% | 加碼 |
| Siren, L.L.C. | 374,000 | $870.7 萬 | 0.38% | +374,000 | 新進 |
| Capital World Investors | 378,573 | $881.3 萬 | 0.00% | +378,573 | 新進 |
| Charles Schwab Investment Management Inc | 379,650 | $883.8 萬 | 0.00% | +46,375+13.9% | 加碼 |