Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、9 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2024 年第 2 季 13F 持有人
Spyre Therapeutics, Inc. 在 2024/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 107
- 較 2024 年第 1 季 +5 家
- 持有股數
- 5,038 萬
- 較 2024 年第 1 季 +1,803 萬 (+55.7%)
- 總市值
- $11.8 億
- 較 2024 年第 1 季 −$2,835 萬 (−2.3%)
- 新進機構
- 29
- 另有 47 家加碼
- 清倉機構
- 24
- 另有 17 家減碼
另有 1 家機構在 2024 年第 1 季持有、還沒有申報 2024 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2024 年第 2 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2024 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 7,507,983 | $1.77 億 | 0.01% | +924,228+14.0% | 加碼 |
| Fairmount Funds Management LLC | 4,018,101 | $9,447 萬 | 10.67% | +3,639,680+961.8% | 加碼 |
| RTW Investments, LP | 3,258,360 | $7,660 萬 | 1.19% | +1,025,600+45.9% | 加碼 |
| Perceptive Advisors LLC | 3,031,018 | $7,126 萬 | 1.72% | +474,339+18.6% | 加碼 |
| VR Adviser, LLC | 2,685,448 | $6,313 萬 | 4.02% | +513,666+23.7% | 加碼 |
| Braidwell LP | 2,514,538 | $5,912 萬 | 1.85% | +1,999,538+388.3% | 加碼 |
| BlackRock Inc. | 2,403,441 | $5,650 萬 | 0.00% | +1,846,750+331.7% | 加碼 |
| Commodore Capital LP | 1,988,084 | $4,674 萬 | 3.19% | +104,000+5.5% | 加碼 |
| Vanguard Group Inc | 1,911,566 | $4,494 萬 | 0.00% | +1,414,385+284.5% | 加碼 |
| Avoro Capital Advisors LLC | 1,839,138 | $4,324 萬 | 0.58% | 00.0% | 不變 |
| Deep Track Capital, LP | 1,756,667 | $4,130 萬 | 1.23% | +543,247+44.8% | 加碼 |
| State Street Corp | 1,409,659 | $3,314 萬 | 0.00% | +1,275,233+948.7% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,152,411 | $2,709 萬 | 0.05% | +47,211+4.3% | 加碼 |
| Goldman Sachs Group Inc | 893,083 | $2,100 萬 | 0.00% | +653,168+272.2% | 加碼 |
| Wellington Management Group LLP | 795,946 | $1,871 萬 | 0.00% | −16,914−2.1% | 減碼 |
| Geode Capital Management, LLC | 765,834 | $1,801 萬 | 0.00% | +435,609+131.9% | 加碼 |
| Franklin Resources Inc | 741,904 | $1,744 萬 | 0.01% | 00.0% | 不變 |
| Citadel Advisors LLC | 707,586 | $1,664 萬 | 0.02% | −40.0% | 減碼 |
| Boxer Capital, LLC | 696,480 | $1,637 萬 | 0.86% | +446,480+178.6% | 加碼 |
| Driehaus Capital Management LLC | 687,080 | $1,615 萬 | 0.16% | 00.0% | 不變 |
| Janus Henderson Group PLC | 673,867 | $1,592 萬 | 0.01% | +659,890+4,721.3% | 加碼 |
| Farallon Capital Management, L.L.C. | 666,000 | $1,566 萬 | 0.09% | +200,000+42.9% | 加碼 |
| Logos Global Management LP | 575,000 | $1,352 萬 | 1.56% | +325,000+130.0% | 加碼 |
| Affinity Asset Advisors, LLC | 513,420 | $1,207 萬 | 1.90% | +103,420+25.2% | 加碼 |
| Polar Capital Holdings Plc | 500,000 | $1,176 萬 | 0.07% | 00.0% | 不變 |
| First Turn Management, LLC | 464,435 | $1,092 萬 | 1.78% | 00.0% | 不變 |
| Darwin Global Management, Ltd. | 452,040 | $1,027 萬 | 1.19% | −21,160−4.5% | 減碼 |
| Morgan Stanley | 408,853 | $961.2 萬 | 0.00% | +357,665+698.7% | 加碼 |
| Pictet Asset Management Holding SA | 386,617 | $908.9 萬 | 0.01% | +386,617 | 新進 |
| Price T Rowe Associates Inc | 307,976 | $724.2 萬 | 0.00% | +229,447+292.2% | 加碼 |
| Blackstone Group Inc. | 292,995 | $688.8 萬 | 0.03% | +273,004+1,365.6% | 加碼 |
| Voloridge Investment Management, LLC | 275,226 | $647.1 萬 | 0.02% | +87,173+46.4% | 加碼 |
| Balyasny Asset Management LLC | 272,636 | $641.0 萬 | 0.02% | +240,239+741.5% | 加碼 |
| Woodline Partners LP | 262,616 | $617.4 萬 | 0.06% | +162,089+161.2% | 加碼 |
| Ghost Tree Capital, LLC | 250,237 | $588.3 萬 | 2.05% | +150,237+150.2% | 加碼 |
| Avidity Partners Management LP | 195,000 | $458.4 萬 | 0.19% | +195,000 | 新進 |
| Bank of America Corp | 191,169 | $449.4 萬 | 0.00% | +154,837+426.2% | 加碼 |
| Walleye Capital LLC | 150,820 | $354.6 萬 | 0.04% | +39,342+35.3% | 加碼 |
| StemPoint Capital LP | 150,450 | $353.7 萬 | 1.04% | +88,197+141.7% | 加碼 |
| Soros Fund Management LLC大師索羅斯基金管理 | 145,000 | $340.9 萬 | 0.08% | +114,962+382.7% | 加碼 |
| Armistice Capital, LLC | 136,000 | $319.7 萬 | 0.08% | +136,000 | 新進 |
| Great Point Partners LLC | 134,612 | $316.5 萬 | 0.61% | +9,612+7.7% | 加碼 |
| Bank of New York Mellon Corp | 117,686 | $276.7 萬 | 0.00% | +111,636+1,845.2% | 加碼 |
| Nuveen Asset Management, LLC | 117,140 | $275.4 萬 | 0.00% | +117,140 | 新進 |
| HighVista Strategies LLC | 113,550 | $267.0 萬 | 0.98% | −40,831−26.4% | 減碼 |
| Suvretta Capital Management, LLC | 107,310 | $252.3 萬 | 0.10% | −55,085−33.9% | 減碼 |
| Candriam Luxembourg S.C.A. | 105,000 | $246.8 萬 | 0.01% | 00.0% | 不變 |
| Integral Health Asset Management, LLC | 100,000 | $235.1 萬 | 0.23% | 00.0% | 不變 |
| Charles Schwab Investment Management Inc | 98,181 | $230.8 萬 | 0.00% | +83,181+554.5% | 加碼 |
| Jefferies Financial Group Inc. | 97,573 | $229.4 萬 | 0.05% | +97,573 | 新進 |
| Northern Trust Corp | 85,588 | $201.2 萬 | 0.00% | +19,248+29.0% | 加碼 |
| Ensign Peak Advisors, Inc | 82,475 | $193.9 萬 | 0.00% | +82,475 | 新進 |
| Schonfeld Strategic Advisors LLC | 78,500 | $184.6 萬 | 0.01% | +43,000+121.1% | 加碼 |
| Norges Bank | 70,843 | $166.6 萬 | 0.00% | +70,843 | 新進 |
| Rafferty Asset Management, LLC | 67,109 | $157.8 萬 | 0.01% | +67,109 | 新進 |
| Jump Financial, LLC | 64,900 | $152.6 萬 | 0.03% | +42,100+184.6% | 加碼 |
| Barclays PLC | 64,043 | $150.6 萬 | 0.00% | +18,081+39.3% | 加碼 |
| Rhumbline Advisers | 51,896 | $122.0 萬 | 0.00% | +51,896 | 新進 |
| Superstring Capital Management LP | 45,571 | $107.1 萬 | 1.35% | +45,571 | 新進 |
| UBS Group AG | 44,504 | $104.6 萬 | 0.00% | +41,903+1,611.0% | 加碼 |
| Manufacturers Life Insurance Company, The | 37,782 | $88.8 萬 | 0.00% | +13,125+53.2% | 加碼 |
| EFG Asset Management (North America) Corp. | 36,781 | $86.9 萬 | 0.15% | +25,630+229.8% | 加碼 |
| Alliancebernstein L.P. | 36,230 | $85.2 萬 | 0.00% | +36,230 | 新進 |
| Swiss National Bank | 36,100 | $84.9 萬 | 0.00% | −3,000−7.7% | 減碼 |
| Bridgeway Capital Management, LLC | 36,100 | $84.9 萬 | 0.02% | +36,100 | 新進 |
| ADAR1 Capital Management, LLC | 35,180 | $82.7 萬 | 0.17% | −14,320−28.9% | 減碼 |
| TD Asset Management Inc | 35,168 | $82.7 萬 | 0.00% | −25,800−42.3% | 減碼 |
| NBW Capital LLC | 34,360 | $80.8 萬 | 0.16% | 00.0% | 不變 |
| Alpine Global Management, LLC | 33,858 | $79.6 萬 | 0.14% | +33,858 | 新進 |
| UBS Asset Management Americas Inc | 30,121 | $70.8 萬 | 0.00% | +30,121 | 新進 |
| Legal & General Group Plc | 23,263 | $54.7 萬 | 0.00% | +6,231+36.6% | 加碼 |
| JPMorgan Chase & Co | 22,772 | $53.5 萬 | 0.00% | +22,761+206,918.2% | 加碼 |
| Citigroup Inc | 19,320 | $45.4 萬 | 0.00% | −12,437−39.2% | 減碼 |
| California State Teachers Retirement System | 19,105 | $44.9 萬 | 0.00% | +1,302+7.3% | 加碼 |
| Corebridge Financial, Inc. | 18,625 | $43.8 萬 | 0.00% | +18,625 | 新進 |
| Global Endowment Management, LP | 18,184 | $42.8 萬 | 0.05% | 00.0% | 不變 |
| EAM Investors, LLC | 17,938 | $42.2 萬 | 0.07% | 00.0% | 不變 |
| Wells Fargo & Company | 17,175 | $40.4 萬 | 0.00% | +14,933+666.1% | 加碼 |
| Invesco Ltd. | 16,364 | $38.5 萬 | 0.00% | −136,214−89.3% | 減碼 |
| Deutsche Bank AG | 16,245 | $38.2 萬 | 0.00% | +15,947+5,351.3% | 加碼 |
| New York State Common Retirement Fund | 14,365 | $33.8 萬 | 0.00% | −305−2.1% | 減碼 |
| State of Wisconsin Investment Board | 13,932 | $32.8 萬 | 0.00% | −700−4.8% | 減碼 |
| Qube Research & Technologies Ltd | 12,672 | $29.8 萬 | 0.00% | −45,006−78.0% | 減碼 |
| Profund Advisors LLC | 12,606 | $29.6 萬 | 0.01% | +12,606 | 新進 |
| Aquatic Capital Management LLC | 11,800 | $27.7 萬 | 0.01% | +11,800 | 新進 |
| Voya Investment Management LLC | 11,607 | $27.3 萬 | 0.00% | +11,607 | 新進 |
| Jane Street Group, LLC | 11,551 | $27.2 萬 | 0.00% | +4,341+60.2% | 加碼 |
| Virtu Financial LLC | 11,016 | $25.9 萬 | 0.02% | −5,197−32.1% | 減碼 |
| Two Sigma Investments, LP | 9,842 | $23.1 萬 | 0.00% | −3,513−26.3% | 減碼 |
| Carlyle Group Inc. | 9,620 | $22.7 萬 | 0.02% | 00.0% | 不變 |
| State Board of Administration of Florida Retirement System | 9,030 | $21.2 萬 | 0.00% | +9,030 | 新進 |
| MetLife Investment Management | 8,788 | $20.7 萬 | 0.00% | +8,788 | 新進 |
| SG Americas Securities, LLC | 5,545 | $13.0 萬 | 0.00% | +5,545 | 新進 |
| Ameritas Investment Partners, Inc. | 3,392 | $7.97 萬 | 0.00% | +3,392 | 新進 |
| Tower Research Capital LLC (TRC) | 3,384 | $7.96 萬 | 0.00% | −444−11.6% | 減碼 |
| Royal Bank of Canada | 3,256 | $7.70 萬 | 0.00% | +3,200+5,714.3% | 加碼 |
| Virtus ETF Advisers LLC | 2,797 | $6.58 萬 | 0.03% | −3,041−52.1% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 2,526 | $5.74 萬 | 0.00% | +2,526 | 新進 |
| Quest Partners LLC | 1,523 | $3.58 萬 | 0.00% | +1,523 | 新進 |
| Amalgamated Bank | 1,198 | $2.80 萬 | 0.00% | +1,198 | 新進 |