Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、9 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2021 年第 2 季 13F 持有人
Spyre Therapeutics, Inc. 在 2021/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 78
- 較 2021 年第 1 季 −6 家
- 持有股數
- 4,107 萬
- 較 2021 年第 1 季 −43.6 萬 (−1.1%)
- 總市值
- $2.86 億
- 較 2021 年第 1 季 −$4,286 萬 (−13.0%)
- 新進機構
- 3
- 另有 29 家加碼
- 清倉機構
- 9
- 另有 26 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2021 年第 2 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2021 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 4,015,524 | $2,795 萬 | 0.29% | 00.0% | 不變 |
| Baker Bros. Advisors LP | 3,410,106 | $2,373 萬 | 0.10% | 00.0% | 不變 |
| BlackRock Inc. | 3,103,879 | $2,161 萬 | 0.00% | −246,433−7.4% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 3,049,581 | $2,123 萬 | 0.04% | +101,440+3.4% | 加碼 |
| Bain Capital Life Sciences Investors, LLC | 2,700,000 | $1,879 萬 | 1.23% | 00.0% | 不變 |
| Pictet Asset Management Ltd | 2,532,799 | $1,763 萬 | 0.02% | +13,465+0.5% | 加碼 |
| Vanguard Group Inc | 2,097,166 | $1,460 萬 | 0.00% | −76,896−3.5% | 減碼 |
| Suvretta Capital Management, LLC | 2,094,100 | $1,458 萬 | 0.22% | +727,027+53.2% | 加碼 |
| Aisling Capital Management LP | 1,691,151 | $1,177 萬 | 1.88% | 00.0% | 不變 |
| Nantahala Capital Management, LLC | 1,677,036 | $1,167 萬 | 0.64% | −35,052−2.0% | 減碼 |
| Rock Springs Capital Management LP | 1,577,296 | $1,098 萬 | 0.22% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 1,131,059 | $787.3 萬 | 0.00% | −5,614−0.5% | 減碼 |
| Artal Group S.A. | 1,045,000 | $727.3 萬 | 0.17% | 00.0% | 不變 |
| Great Point Partners LLC | 900,000 | $626.4 萬 | 1.40% | +397,100+79.0% | 加碼 |
| Samsara BioCapital, LLC | 883,720 | $615.1 萬 | 0.81% | 00.0% | 不變 |
| State Street Corp | 757,500 | $527.2 萬 | 0.00% | +39,025+5.4% | 加碼 |
| Geode Capital Management, LLC | 677,726 | $471.6 萬 | 0.00% | +19,856+3.0% | 加碼 |
| Marshall Wace, LLP | 651,403 | $453.4 萬 | 0.02% | −539,836−45.3% | 減碼 |
| Altium Capital Management LP | 609,689 | $424.3 萬 | 0.98% | +341,936+127.7% | 加碼 |
| Dimensional Fund Advisors LP | 604,112 | $420.5 萬 | 0.00% | +10,695+1.8% | 加碼 |
| Boxer Capital, LLC | 550,000 | $382.8 萬 | 0.14% | 00.0% | 不變 |
| Millennium Management LLC | 543,185 | $378.1 萬 | 0.00% | +172,049+46.4% | 加碼 |
| Point72 Asset Management, L.P. | 469,765 | $327.0 萬 | 0.02% | −1,030,235−68.7% | 減碼 |
| AXA S.A. | 424,352 | $295.3 萬 | 0.01% | +432+0.1% | 加碼 |
| Sio Capital Management, LLC | 402,653 | $280.2 萬 | 0.76% | 00.0% | 不變 |
| Northern Trust Corp | 368,340 | $256.4 萬 | 0.00% | −82,980−18.4% | 減碼 |
| Lion Point Capital, LP | 300,000 | $208.8 萬 | 0.49% | 00.0% | 不變 |
| Assenagon Asset Management S.A. | 282,068 | $196.3 萬 | 0.01% | +134,278+90.9% | 加碼 |
| University of Texas/Texas Am Investment Managment Co | 269,578 | $187.6 萬 | 1.44% | −10,100−3.6% | 減碼 |
| Abingworth LLP | 240,500 | $167.1 萬 | 0.52% | 00.0% | 不變 |
| Morgan Stanley | 195,535 | $136.2 萬 | 0.00% | +84,445+76.0% | 加碼 |
| Nuveen Asset Management, LLC | 184,271 | $128.3 萬 | 0.00% | +26,400+16.7% | 加碼 |
| Ritholtz Wealth Management | 174,646 | $121.6 萬 | 0.09% | 00.0% | 不變 |
| Bank of New York Mellon Corp | 147,401 | $102.6 萬 | 0.00% | +4,128+2.9% | 加碼 |
| Fan Yu | 112,044 | $78.0 萬 | 8.81% | 00.0% | 不變 |
| Charles Schwab Investment Management Inc | 105,779 | $73.7 萬 | 0.00% | −5,004−4.5% | 減碼 |
| Franklin Street Advisors Inc | 103,600 | $72.1 萬 | 0.06% | 00.0% | 不變 |
| AlphaCentric Advisors LLC | 92,500 | $64.4 萬 | 0.17% | +71,500+340.5% | 加碼 |
| JPMorgan Chase & Co | 87,633 | $61.0 萬 | 0.00% | +58,637+202.2% | 加碼 |
| Jacobs Levy Equity Management, Inc | 59,294 | $41.3 萬 | 0.00% | −130,139−68.7% | 減碼 |
| California State Teachers Retirement System | 55,861 | $38.9 萬 | 0.00% | −12,414−18.2% | 減碼 |
| Rhumbline Advisers | 52,667 | $36.7 萬 | 0.00% | +6,335+13.7% | 加碼 |
| Blair William & Co | 52,204 | $36.3 萬 | 0.00% | 00.0% | 不變 |
| UBS Group AG | 52,077 | $36.2 萬 | 0.00% | +2,104+4.2% | 加碼 |
| Renaissance Technologies LLC | 50,787 | $35.3 萬 | 0.00% | +40,287+383.7% | 加碼 |
| D. E. Shaw & Co., Inc. | 45,981 | $32.0 萬 | 0.00% | −16,766−26.7% | 減碼 |
| Algert Global LLC | 41,500 | $28.9 萬 | 0.10% | −25,320−37.9% | 減碼 |
| Ergoteles LLC | 34,100 | $23.7 萬 | 0.01% | +34,100 | 新進 |
| Parametric Portfolio Associates LLC | 33,148 | $23.1 萬 | 0.00% | +6,558+24.7% | 加碼 |
| New York State Common Retirement Fund | 31,484 | $21.9 萬 | 0.00% | +384+1.2% | 加碼 |
| Manufacturers Life Insurance Company, The | 26,523 | $18.5 萬 | 0.00% | −2,574−8.8% | 減碼 |
| Alliancebernstein L.P. | 25,600 | $17.8 萬 | 0.00% | +2,200+9.4% | 加碼 |
| Deutsche Bank AG | 23,993 | $16.7 萬 | 0.00% | −6,725−21.9% | 減碼 |
| Russell Investments Group, Ltd. | 24,035 | $16.5 萬 | 0.00% | −60,446−71.5% | 減碼 |
| American International Group, Inc. | 22,645 | $15.8 萬 | 0.00% | −3,665−13.9% | 減碼 |
| California Public Employees Retirement System | 20,841 | $14.5 萬 | 0.00% | −64,459−75.6% | 減碼 |
| Bank of America Corp | 20,216 | $14.1 萬 | 0.00% | −19,474−49.1% | 減碼 |
| Voya Investment Management LLC | 19,878 | $13.8 萬 | 0.00% | −1,616−7.5% | 減碼 |
| ProShare Advisors LLC | 19,293 | $13.4 萬 | 0.00% | +596+3.2% | 加碼 |
| Cerity Partners LLC | 18,000 | $12.5 萬 | 0.00% | +18,000 | 新進 |
| Invesco Ltd. | 13,045 | $9.00 萬 | 0.00% | +13,045 | 新進 |
| Cubist Systematic Strategies, LLC | 11,722 | $8.20 萬 | 0.00% | −6,113−34.3% | 減碼 |
| Personal Cfo Solutions, LLC | 11,388 | $7.90 萬 | 0.02% | 00.0% | 不變 |
| Barclays PLC | 5,668 | $4.00 萬 | 0.00% | −32,294−85.1% | 減碼 |
| Citigroup Inc | 4,983 | $3.50 萬 | 0.00% | +872+21.2% | 加碼 |
| BNP Paribas Arbitrage, SA | 4,705 | $3.27 萬 | 0.00% | −2,255−32.4% | 減碼 |
| IFP Advisors, Inc | 3,980 | $2.70 萬 | 0.00% | +500+14.4% | 加碼 |
| Ameritas Investment Partners, Inc. | 3,710 | $2.60 萬 | 0.00% | 00.0% | 不變 |
| Legal & General Group Plc | 3,264 | $2.30 萬 | 0.00% | −1,509−31.6% | 減碼 |
| Tower Research Capital LLC (TRC) | 3,021 | $2.10 萬 | 0.00% | +372+14.0% | 加碼 |
| Royal Bank of Canada | 2,966 | $2.00 萬 | 0.00% | −983−24.9% | 減碼 |
| Wells Fargo & Company | 2,212 | $1.60 萬 | 0.00% | −9,619−81.3% | 減碼 |
| O'Shaughnessy Asset Management, LLC | 1,654 | $1.20 萬 | 0.00% | 00.0% | 不變 |
| Quadrant Capital Group LLC | 1,137 | $8,000 | 0.00% | 00.0% | 不變 |
| Penserra Capital Management LLC | 1,115 | $7,000 | 0.00% | +25+2.3% | 加碼 |
| Group One Trading, L.P. | 300 | $2,000 | 0.00% | +100+50.0% | 加碼 |
| Daiwa Securities Group Inc. | 98 | $1,000 | 0.00% | 00.0% | 不變 |
| Ellevest, Inc. | 150 | $1,000 | 0.00% | +37+32.7% | 加碼 |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −175,000−100.0% | 清倉 |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −60,300−100.0% | 清倉 |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −33,800−100.0% | 清倉 |
| MetLife Investment Management | 0 | $0 | 0.00% | −20,285−100.0% | 清倉 |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −18,332−100.0% | 清倉 |
| Metropolitan Life Insurance Co | 0 | $0 | 0.00% | −12,039−100.0% | 清倉 |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −10,800−100.0% | 清倉 |
| Bank of Montreal | 0 | $0 | 0.00% | −3,727−100.0% | 清倉 |
| FNY Investment Advisers, LLC | 0 | $0 | 0.00% | −1,500−100.0% | 清倉 |