Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、9 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2022 年第 1 季 13F 持有人
Spyre Therapeutics, Inc. 在 2022/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 84
- 較 2021 年第 4 季 −2 家
- 持有股數
- 4,146 萬
- 較 2021 年第 4 季 +154.4 萬 (+3.9%)
- 總市值
- $9,538 萬
- 較 2021 年第 4 季 −$9,406 萬 (−49.7%)
- 新進機構
- 10
- 另有 29 家加碼
- 清倉機構
- 12
- 另有 25 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2022 年第 1 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2021 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Suvretta Capital Management, LLC | 4,059,894 | $933.8 萬 | 0.29% | +1,488,894+57.9% | 加碼 |
| Baker Bros. Advisors LP | 3,410,106 | $784.3 萬 | 0.05% | 00.0% | 不變 |
| Nantahala Capital Management, LLC | 3,200,593 | $736.1 萬 | 0.51% | +387,033+13.8% | 加碼 |
| OrbiMed Advisors LLC | 2,956,124 | $679.9 萬 | 0.11% | 00.0% | 不變 |
| BlackRock Inc. | 2,921,810 | $671.9 萬 | 0.00% | −76,669−2.6% | 減碼 |
| Bain Capital Life Sciences Investors, LLC | 2,847,689 | $655.0 萬 | 0.64% | 00.0% | 不變 |
| Pictet Asset Management SA | 2,552,434 | $587.1 萬 | 0.01% | +84,305+3.4% | 加碼 |
| Vanguard Group Inc | 2,117,323 | $486.9 萬 | 0.00% | −3,302−0.2% | 減碼 |
| Rock Springs Capital Management LP | 1,811,425 | $416.6 萬 | 0.10% | +234,129+14.8% | 加碼 |
| Aisling Capital Management LP | 1,691,151 | $389.0 萬 | 2.10% | 00.0% | 不變 |
| Laurion Capital Management LP | 1,575,638 | $362.4 萬 | 0.09% | +125,000+8.6% | 加碼 |
| Goldman Sachs Group Inc | 1,124,789 | $258.7 萬 | 0.00% | −9,562−0.8% | 減碼 |
| Samsara BioCapital, LLC | 883,720 | $203.3 萬 | 0.51% | 00.0% | 不變 |
| Sio Capital Management, LLC | 871,101 | $200.4 萬 | 0.81% | +372,601+74.7% | 加碼 |
| State Street Corp | 787,048 | $181.0 萬 | 0.00% | +29,007+3.8% | 加碼 |
| Geode Capital Management, LLC | 692,221 | $159.2 萬 | 0.00% | +6,476+0.9% | 加碼 |
| Ghost Tree Capital, LLC | 686,599 | $157.9 萬 | 0.78% | +686,599 | 新進 |
| Dimensional Fund Advisors LP | 680,964 | $156.6 萬 | 0.00% | −9,609−1.4% | 減碼 |
| Assenagon Asset Management S.A. | 523,142 | $120.3 萬 | 0.00% | +106,968+25.7% | 加碼 |
| Deutsche Bank AG | 515,133 | $118.5 萬 | 0.00% | +490,598+1,999.6% | 加碼 |
| D. E. Shaw & Co., Inc. | 454,093 | $104.5 萬 | 0.00% | +226,585+99.6% | 加碼 |
| Jacobs Levy Equity Management, Inc | 436,183 | $100.3 萬 | 0.01% | +292,090+202.7% | 加碼 |
| Millennium Management LLC | 423,914 | $97.5 萬 | 0.00% | +233,432+122.5% | 加碼 |
| Northern Trust Corp | 333,741 | $76.8 萬 | 0.00% | −15,947−4.6% | 減碼 |
| Lion Point Capital, LP | 300,000 | $69.0 萬 | 0.23% | 00.0% | 不變 |
| University of Texas/Texas Am Investment Managment Co | 245,678 | $56.5 萬 | 0.29% | 00.0% | 不變 |
| Abingworth LLP | 240,500 | $55.3 萬 | 0.16% | 00.0% | 不變 |
| Two Sigma Investments, LP | 216,601 | $49.8 萬 | 0.00% | +152,090+235.8% | 加碼 |
| Nuveen Asset Management, LLC | 169,120 | $42.5 萬 | 0.00% | +298+0.2% | 加碼 |
| ClariVest Asset Management LLC | 184,119 | $42.4 萬 | 0.02% | +9,200+5.3% | 加碼 |
| Morgan Stanley | 181,701 | $41.8 萬 | 0.00% | −14,517−7.4% | 減碼 |
| Parametric Portfolio Associates LLC | 178,016 | $40.9 萬 | 0.00% | +136,033+324.0% | 加碼 |
| Two Sigma Advisers, LP | 161,300 | $37.1 萬 | 0.00% | +123,100+322.3% | 加碼 |
| Bank of New York Mellon Corp | 157,657 | $36.2 萬 | 0.00% | −1,617−1.0% | 減碼 |
| Marshall Wace, LLP | 154,175 | $35.5 萬 | 0.00% | +112,551+270.4% | 加碼 |
| Renaissance Technologies LLC | 151,868 | $34.9 萬 | 0.00% | −96,332−38.8% | 減碼 |
| Acadian Asset Management LLC | 149,399 | $34.2 萬 | 0.00% | +18,564+14.2% | 加碼 |
| Walleye Capital LLC | 135,611 | $31.2 萬 | 0.01% | +135,611 | 新進 |
| Bridgeway Capital Management, LLC | 123,000 | $28.3 萬 | 0.01% | +123,000 | 新進 |
| Fan Yu | 112,044 | $25.8 萬 | 3.49% | 00.0% | 不變 |
| Charles Schwab Investment Management Inc | 106,810 | $24.6 萬 | 0.00% | +7,333+7.4% | 加碼 |
| Franklin Street Advisors Inc | 105,800 | $24.3 萬 | 0.02% | 00.0% | 不變 |
| Blair William & Co | 76,594 | $17.6 萬 | 0.00% | 00.0% | 不變 |
| Ritholtz Wealth Management | 76,490 | $17.6 萬 | 0.01% | 00.0% | 不變 |
| Citadel Advisors LLC | 73,414 | $16.9 萬 | 0.00% | +73,414 | 新進 |
| UBS Group AG | 65,276 | $15.0 萬 | 0.00% | −71,360−52.2% | 減碼 |
| Algert Global LLC | 56,944 | $13.1 萬 | 0.01% | +24,520+75.6% | 加碼 |
| Alps Advisors Inc | 50,735 | $11.7 萬 | 0.00% | −6,345−11.1% | 減碼 |
| Rhumbline Advisers | 48,918 | $11.3 萬 | 0.00% | −5,000−9.3% | 減碼 |
| Franklin Resources Inc | 46,300 | $10.6 萬 | 0.00% | +46,300 | 新進 |
| AQR Capital Management LLC | 36,787 | $8.50 萬 | 0.00% | +36,787 | 新進 |
| JPMorgan Chase & Co | 24,923 | $5.80 萬 | 0.00% | +4,045+19.4% | 加碼 |
| BIT Capital GmbH | 25,000 | $5.75 萬 | 0.01% | 00.0% | 不變 |
| Tower Research Capital LLC (TRC) | 22,079 | $5.10 萬 | 0.00% | +17,127+345.9% | 加碼 |
| Alliancebernstein L.P. | 21,600 | $5.00 萬 | 0.00% | −4,000−15.6% | 減碼 |
| American International Group, Inc. | 20,064 | $4.60 萬 | 0.00% | −1,412−6.6% | 減碼 |
| Bank of America Corp | 18,005 | $4.10 萬 | 0.00% | −13,062−42.0% | 減碼 |
| California State Teachers Retirement System | 17,202 | $4.00 萬 | 0.00% | −4,112−19.3% | 減碼 |
| New York State Common Retirement Fund | 17,041 | $3.90 萬 | 0.00% | 00.0% | 不變 |
| Voya Investment Management LLC | 15,466 | $3.60 萬 | 0.00% | 00.0% | 不變 |
| ProShare Advisors LLC | 12,680 | $2.90 萬 | 0.00% | −3,091−19.6% | 減碼 |
| Invesco Ltd. | 12,350 | $2.90 萬 | 0.00% | +138+1.1% | 加碼 |
| Cubist Systematic Strategies, LLC | 12,096 | $2.80 萬 | 0.00% | −43,849−78.4% | 減碼 |
| Manufacturers Life Insurance Company, The | 11,679 | $2.69 萬 | 0.00% | −8,460−42.0% | 減碼 |
| Public Employees Retirement System of Ohio | 8,189 | $1.90 萬 | 0.00% | +4,296+110.4% | 加碼 |
| Barclays PLC | 6,660 | $1.60 萬 | 0.00% | −42,493−86.5% | 減碼 |
| Wells Fargo & Company | 7,025 | $1.60 萬 | 0.00% | −14,307−67.1% | 減碼 |
| Amalgamated Bank | 4,887 | $1.10 萬 | 0.00% | +4,887 | 新進 |
| Amalgamated Financial Corp. | 4,887 | $1.10 萬 | 0.00% | +4,887 | 新進 |
| Citigroup Inc | 4,319 | $1.00 萬 | 0.00% | −7,575−63.7% | 減碼 |
| Ameritas Investment Partners, Inc. | 3,710 | $9,000 | 0.00% | 00.0% | 不變 |
| Point72 Hong Kong Ltd | 3,921 | $9,000 | 0.00% | +3,768+2,462.7% | 加碼 |
| BNP Paribas Arbitrage, SA | 3,580 | $8,234 | 0.00% | −7,579−67.9% | 減碼 |
| Legal & General Group Plc | 3,264 | $8,000 | 0.00% | 00.0% | 不變 |
| Group One Trading, L.P. | 3,000 | $7,000 | 0.00% | −2,300−43.4% | 減碼 |
| Royal Bank of Canada | 2,483 | $6,000 | 0.00% | −5,677−69.6% | 減碼 |
| Russell Investments Group, Ltd. | 3,008 | $6,000 | 0.00% | 00.0% | 不變 |
| Allspring Global Investments Holdings, LLC | 1,151 | $2,000 | 0.00% | −183−13.7% | 減碼 |
| Captrust Financial Advisors | 1,084 | $2,000 | 0.00% | +913+533.9% | 加碼 |
| Toronto Dominion Bank | 5 | $0 | 0.00% | 00.0% | 不變 |
| Daiwa Securities Group Inc. | 98 | $0 | 0.00% | 00.0% | 不變 |
| FMR LLC | 121 | $0 | 0.00% | +121 | 新進 |
| Glassman Wealth Services | 88 | $0 | 0.00% | +88 | 新進 |
| IFP Advisors, Inc | 5,840 | – | – | +2,860+96.0% | 加碼 |
| Artal Group S.A. | 0 | $0 | 0.00% | −1,045,000−100.0% | 清倉 |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −1,000,000−100.0% | 清倉 |
| Great Point Partners LLC | 0 | $0 | 0.00% | −910,251−100.0% | 清倉 |
| AXA S.A. | 0 | $0 | 0.00% | −444,931−100.0% | 清倉 |
| Altium Capital Management LP | 0 | $0 | 0.00% | −293,764−100.0% | 清倉 |
| Aristides Capital LLC | 0 | $0 | 0.00% | −35,763−100.0% | 清倉 |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −15,000−100.0% | 清倉 |
| Delphia (USA) Inc. | 0 | $0 | 0.00% | −12,944−100.0% | 清倉 |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −13,192−100.0% | 清倉 |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −11,033−100.0% | 清倉 |
| Pinnacle Wealth Planning Services, Inc. | 0 | $0 | 0.00% | −10,130−100.0% | 清倉 |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −1,137−100.0% | 清倉 |