Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、9 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2022 年第 2 季 13F 持有人
Spyre Therapeutics, Inc. 在 2022/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 67
- 較 2022 年第 1 季 −15 家
- 持有股數
- 4,941 萬
- 較 2022 年第 1 季 +813.4 萬 (+19.7%)
- 總市值
- $2,481 萬
- 較 2022 年第 1 季 −$7,014 萬 (−73.9%)
- 新進機構
- 14
- 另有 21 家加碼
- 清倉機構
- 29
- 另有 18 家減碼
另有 2 家機構在 2022 年第 1 季持有、還沒有申報 2022 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2022 年第 2 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2022 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 5,347,689 | $270.1 萬 | 0.32% | +2,500,000+87.8% | 加碼 |
| Pictet Asset Management SA | 4,890,502 | $247.0 萬 | 0.00% | +2,338,068+91.6% | 加碼 |
| Sio Capital Management, LLC | 4,668,536 | $235.8 萬 | 0.93% | +3,797,435+435.9% | 加碼 |
| Suvretta Capital Management, LLC | 4,059,894 | $205.1 萬 | 0.08% | 00.0% | 不變 |
| Nantahala Capital Management, LLC | 3,877,311 | $195.8 萬 | 0.17% | +676,718+21.1% | 加碼 |
| Baker Bros. Advisors LP | 3,410,106 | $172.2 萬 | 0.01% | 00.0% | 不變 |
| Rock Springs Capital Management LP | 3,072,034 | $155.2 萬 | 0.05% | +1,260,609+69.6% | 加碼 |
| Great Point Partners LLC | 2,500,000 | $126.3 萬 | 0.33% | +2,500,000 | 新進 |
| Vanguard Group Inc | 1,948,009 | $98.4 萬 | 0.00% | −169,314−8.0% | 減碼 |
| OrbiMed Advisors LLC | 1,797,221 | $90.8 萬 | 0.02% | −1,158,903−39.2% | 減碼 |
| Aisling Capital Management LP | 1,691,151 | $85.4 萬 | 0.61% | 00.0% | 不變 |
| Adage Capital Partners GP, L.L.C. | 1,500,000 | $75.8 萬 | 0.00% | +1,500,000 | 新進 |
| Goldman Sachs Group Inc | 1,187,293 | $60.0 萬 | 0.00% | +62,504+5.6% | 加碼 |
| BlackRock Inc. | 1,069,602 | $54.0 萬 | 0.00% | −1,852,208−63.4% | 減碼 |
| Ghost Tree Capital, LLC | 925,000 | $46.7 萬 | 0.32% | +238,401+34.7% | 加碼 |
| Samsara BioCapital, LLC | 883,720 | $44.6 萬 | 0.12% | 00.0% | 不變 |
| Assenagon Asset Management S.A. | 642,835 | $32.5 萬 | 0.00% | +119,693+22.9% | 加碼 |
| Renaissance Technologies LLC | 582,444 | $29.4 萬 | 0.00% | +430,576+283.5% | 加碼 |
| Millennium Management LLC | 521,915 | $26.4 萬 | 0.00% | +98,001+23.1% | 加碼 |
| Dimensional Fund Advisors LP | 506,326 | $25.5 萬 | 0.00% | −174,638−25.6% | 減碼 |
| D. E. Shaw & Co., Inc. | 476,404 | $24.1 萬 | 0.00% | +22,311+4.9% | 加碼 |
| Acadian Asset Management LLC | 413,387 | $20.8 萬 | 0.00% | +263,988+176.7% | 加碼 |
| Geode Capital Management, LLC | 394,020 | $19.9 萬 | 0.00% | −298,201−43.1% | 減碼 |
| Two Sigma Investments, LP | 315,840 | $16.0 萬 | 0.00% | +99,239+45.8% | 加碼 |
| Morgan Stanley | 293,834 | $14.8 萬 | 0.00% | +112,133+61.7% | 加碼 |
| University of Texas/Texas Am Investment Managment Co | 245,678 | $12.4 萬 | 0.05% | 00.0% | 不變 |
| Abingworth LLP | 240,500 | $12.1 萬 | 0.04% | 00.0% | 不變 |
| Two Sigma Advisers, LP | 231,700 | $11.7 萬 | 0.00% | +70,400+43.6% | 加碼 |
| Citadel Advisors LLC | 227,195 | $11.5 萬 | 0.00% | +153,781+209.5% | 加碼 |
| State Street Corp | 158,989 | $8.00 萬 | 0.00% | −628,059−79.8% | 減碼 |
| Ergoteles LLC | 147,200 | $7.40 萬 | 0.00% | +147,200 | 新進 |
| Fan Yu | 112,044 | $5.70 萬 | 0.88% | 00.0% | 不變 |
| Franklin Street Advisors Inc | 105,800 | $5.30 萬 | 0.01% | 00.0% | 不變 |
| Blair William & Co | 76,594 | $3.90 萬 | 0.00% | 00.0% | 不變 |
| Ritholtz Wealth Management | 76,490 | $3.90 萬 | 0.00% | 00.0% | 不變 |
| UBS Group AG | 76,806 | $3.90 萬 | 0.00% | +11,530+17.7% | 加碼 |
| Northern Trust Corp | 69,209 | $3.50 萬 | 0.00% | −264,532−79.3% | 減碼 |
| Susquehanna International Group, LLP | 65,195 | $3.30 萬 | 0.00% | +65,195 | 新進 |
| Bridgeway Capital Management, LLC | 48,643 | $2.50 萬 | 0.00% | −74,357−60.5% | 減碼 |
| Qube Research & Technologies Ltd | 40,961 | $2.10 萬 | 0.00% | +40,961 | 新進 |
| Franklin Resources Inc | 31,364 | $1.60 萬 | 0.00% | −14,936−32.3% | 減碼 |
| Virtu Financial LLC | 31,151 | $1.60 萬 | 0.00% | +31,151 | 新進 |
| Bank of New York Mellon Corp | 25,136 | $1.30 萬 | 0.00% | −132,521−84.1% | 減碼 |
| BIT Capital GmbH | 25,000 | $1.26 萬 | 0.00% | 00.0% | 不變 |
| LMR Partners LLP | 19,220 | $1.00 萬 | 0.00% | +19,220 | 新進 |
| SG Americas Securities, LLC | 17,822 | $9,000 | 0.00% | +17,822 | 新進 |
| Tower Research Capital LLC (TRC) | 15,689 | $8,000 | 0.00% | −6,390−28.9% | 減碼 |
| Man Group plc | – | $8,000 | 0.00% | – | 新進 |
| Schonfeld Strategic Advisors LLC | 10,100 | $5,000 | 0.00% | +10,100 | 新進 |
| Bank of America Corp | 7,301 | $4,000 | 0.00% | −10,704−59.5% | 減碼 |
| Citigroup Inc | 5,176 | $3,000 | 0.00% | +857+19.8% | 加碼 |
| BNP Paribas Arbitrage, SA | 5,269 | $2,661 | 0.00% | +1,689+47.2% | 加碼 |
| Legal & General Group Plc | 3,264 | $2,000 | 0.00% | 00.0% | 不變 |
| Group One Trading, L.P. | 3,100 | $2,000 | 0.00% | +100+3.3% | 加碼 |
| JPMorgan Chase & Co | 2,322 | $1,000 | 0.00% | −22,601−90.7% | 減碼 |
| Wells Fargo & Company | 2,443 | $1,000 | 0.00% | −4,582−65.2% | 減碼 |
| FMR LLC | 1,494 | $1,000 | 0.00% | +1,373+1,134.7% | 加碼 |
| Federated Hermes, Inc. | 1,930 | $1,000 | 0.00% | +1,930 | 新進 |
| New York State Common Retirement Fund | 341 | $0 | 0.00% | −16,700−98.0% | 減碼 |
| Barclays PLC | 99 | $0 | 0.00% | −6,561−98.5% | 減碼 |
| Royal Bank of Canada | 674 | $0 | 0.00% | −1,809−72.9% | 減碼 |
| Daiwa Securities Group Inc. | 98 | $0 | 0.00% | 00.0% | 不變 |
| Credit Suisse AG | 21 | $0 | 0.00% | +21 | 新進 |
| Simplex Trading, LLC | 13 | $0 | 0.00% | +13 | 新進 |
| Advisor Group Holdings, Inc. | 470 | $0 | 0.00% | +470 | 新進 |
| Lion Point Capital, LP | 300,000 | – | – | 00.0% | 不變 |
| IFP Advisors, Inc | 2,860 | – | – | −2,980−51.0% | 減碼 |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −1,575,638−100.0% | 清倉 |
| Deutsche Bank AG | 0 | $0 | 0.00% | −515,133−100.0% | 清倉 |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −436,183−100.0% | 清倉 |
| Nuveen Asset Management, LLC | 0 | $0 | 0.00% | −169,120−100.0% | 清倉 |
| ClariVest Asset Management LLC | 0 | $0 | 0.00% | −184,119−100.0% | 清倉 |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −154,175−100.0% | 清倉 |
| Walleye Capital LLC | 0 | $0 | 0.00% | −135,611−100.0% | 清倉 |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −106,810−100.0% | 清倉 |
| Algert Global LLC | 0 | $0 | 0.00% | −56,944−100.0% | 清倉 |
| Alps Advisors Inc | 0 | $0 | 0.00% | −50,735−100.0% | 清倉 |
| Rhumbline Advisers | 0 | $0 | 0.00% | −48,918−100.0% | 清倉 |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −36,787−100.0% | 清倉 |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −21,600−100.0% | 清倉 |
| American International Group, Inc. | 0 | $0 | 0.00% | −20,064−100.0% | 清倉 |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −17,202−100.0% | 清倉 |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −15,466−100.0% | 清倉 |
| Invesco Ltd. | 0 | $0 | 0.00% | −12,350−100.0% | 清倉 |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −12,680−100.0% | 清倉 |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −12,096−100.0% | 清倉 |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −11,679−100.0% | 清倉 |
| Public Employees Retirement System of Ohio | 0 | $0 | 0.00% | −8,189−100.0% | 清倉 |
| Amalgamated Bank | 0 | $0 | 0.00% | −4,887−100.0% | 清倉 |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −3,710−100.0% | 清倉 |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −3,921−100.0% | 清倉 |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −3,008−100.0% | 清倉 |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −1,084−100.0% | 清倉 |
| Allspring Global Investments Holdings, LLC | 0 | $0 | 0.00% | −1,151−100.0% | 清倉 |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −5−100.0% | 清倉 |
| Glassman Wealth Services | 0 | $0 | 0.00% | −88−100.0% | 清倉 |
| Parametric Portfolio Associates LLC | – | – | – | – | 本季未申報 |
| Amalgamated Financial Corp. | – | – | – | – | 本季未申報 |