Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、9 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2024 年第 1 季 13F 持有人
Spyre Therapeutics, Inc. 在 2024/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 103
- 較 2023 年第 4 季 +49 家
- 持有股數
- 3,238 萬
- 較 2023 年第 4 季 +436.9 萬 (+15.6%)
- 總市值
- $12.1 億
- 較 2023 年第 4 季 +$6.12 億 (+101.9%)
- 新進機構
- 55
- 另有 20 家加碼
- 清倉機構
- 6
- 另有 15 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2024 年第 1 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2023 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 6,583,755 | $2.47 億 | 0.02% | +2,797,878+73.9% | 加碼 |
| Perceptive Advisors LLC | 2,556,679 | $9,697 萬 | 1.71% | −50,000−1.9% | 減碼 |
| RTW Investments, LP | 2,232,760 | $8,469 萬 | 1.25% | 00.0% | 不變 |
| VR Adviser, LLC | 2,171,782 | $8,238 萬 | 3.92% | −200,932−8.5% | 減碼 |
| Commodore Capital LP | 1,884,084 | $7,146 萬 | 4.78% | 00.0% | 不變 |
| Avoro Capital Advisors LLC | 1,839,138 | $6,976 萬 | 0.81% | 00.0% | 不變 |
| Deep Track Capital, LP | 1,213,420 | $4,603 萬 | 1.32% | −739,340−37.9% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 1,105,200 | $4,192 萬 | 0.08% | +105,200+10.5% | 加碼 |
| Wellington Management Group LLP | 812,860 | $3,083 萬 | 0.01% | +177,405+27.9% | 加碼 |
| Franklin Resources Inc | 741,904 | $2,814 萬 | 0.01% | +54,814+8.0% | 加碼 |
| Citadel Advisors LLC | 707,590 | $2,684 萬 | 0.03% | +130,879+22.7% | 加碼 |
| Driehaus Capital Management LLC | 687,080 | $2,606 萬 | 0.26% | −84,822−11.0% | 減碼 |
| BlackRock Inc. | 556,691 | $2,112 萬 | 0.00% | +536,929+2,717.0% | 加碼 |
| Braidwell LP | 515,000 | $1,953 萬 | 0.63% | 00.0% | 不變 |
| Polar Capital Holdings Plc | 500,000 | $1,897 萬 | 0.11% | 00.0% | 不變 |
| Vanguard Group Inc | 497,181 | $1,886 萬 | 0.00% | +457,735+1,160.4% | 加碼 |
| Darwin Global Management, Ltd. | 473,200 | $1,795 萬 | 2.39% | +473,200 | 新進 |
| Farallon Capital Management, L.L.C. | 466,000 | $1,768 萬 | 0.10% | +466,000 | 新進 |
| First Turn Management, LLC | 464,435 | $1,762 萬 | 2.64% | +464,435 | 新進 |
| Fan Yu | 737,000 | $1,645 萬 | 22.68% | +737,000 | 新進 |
| Affinity Asset Advisors, LLC | 410,000 | $1,555 萬 | 2.53% | −107,554−20.8% | 減碼 |
| Fairmount Funds Management LLC | 378,421 | $1,435 萬 | 1.56% | 00.0% | 不變 |
| Geode Capital Management, LLC | 330,225 | $1,253 萬 | 0.00% | +299,899+988.9% | 加碼 |
| Millennium Management LLC | 319,563 | $1,212 萬 | 0.01% | +211,077+194.6% | 加碼 |
| Cormorant Asset Management, LP | 250,000 | $948.3 萬 | 0.42% | −687,080−73.3% | 減碼 |
| Boxer Capital, LLC | 250,000 | $948.3 萬 | 0.47% | 00.0% | 不變 |
| Logos Global Management LP | 250,000 | $948.3 萬 | 1.00% | +100,000+66.7% | 加碼 |
| Goldman Sachs Group Inc | 239,915 | $910.0 萬 | 0.00% | +239,915 | 新進 |
| Voloridge Investment Management, LLC | 188,053 | $713.3 萬 | 0.03% | +188,053 | 新進 |
| Suvretta Capital Management, LLC | 162,395 | $616.0 萬 | 0.26% | 00.0% | 不變 |
| Marshall Wace, LLP | 161,921 | $614.2 萬 | 0.01% | +141,669+699.5% | 加碼 |
| HighVista Strategies LLC | 154,381 | $585.6 萬 | 2.09% | −423,235−73.3% | 減碼 |
| Invesco Ltd. | 152,578 | $578.7 萬 | 0.00% | +152,578 | 新進 |
| State Street Corp | 134,426 | $509.9 萬 | 0.00% | +134,426 | 新進 |
| Great Point Partners LLC | 125,000 | $474.1 萬 | 0.74% | 00.0% | 不變 |
| Walleye Capital LLC | 111,478 | $422.8 萬 | 0.05% | +111,478 | 新進 |
| Candriam Luxembourg S.C.A. | 105,000 | $398.3 萬 | 0.03% | +105,000 | 新進 |
| Susquehanna International Group, LLP | 101,503 | $385.0 萬 | 0.01% | +101,503 | 新進 |
| Woodline Partners LP | 100,527 | $381.3 萬 | 0.04% | +100,527 | 新進 |
| Ghost Tree Capital, LLC | 100,000 | $379.3 萬 | 1.22% | +100,000 | 新進 |
| Integral Health Asset Management, LLC | 100,000 | $379.3 萬 | 0.37% | +100,000 | 新進 |
| Nicholas Investment Partners, LP | 89,962 | $341.2 萬 | 0.35% | +89,962 | 新進 |
| HRT Financial LP | 78,996 | $299.6 萬 | 0.02% | +78,996 | 新進 |
| Price T Rowe Associates Inc | 78,529 | $297.9 萬 | 0.00% | +78,529 | 新進 |
| Northern Trust Corp | 66,340 | $251.6 萬 | 0.00% | +66,340 | 新進 |
| Assenagon Asset Management S.A. | 64,400 | $244.3 萬 | 0.01% | +64,400 | 新進 |
| StemPoint Capital LP | 62,253 | $236.1 萬 | 0.63% | −316,513−83.6% | 減碼 |
| TD Asset Management Inc | 60,968 | $231.3 萬 | 0.00% | +60,968 | 新進 |
| Qube Research & Technologies Ltd | 57,678 | $218.8 萬 | 0.00% | +57,678 | 新進 |
| Morgan Stanley | 51,188 | $194.2 萬 | 0.00% | +51,148+127,870.0% | 加碼 |
| ADAR1 Capital Management, LLC | 49,500 | $187.8 萬 | 0.51% | +43,060+668.6% | 加碼 |
| Renaissance Technologies LLC | 49,468 | $187.6 萬 | 0.00% | +932+1.9% | 加碼 |
| Cubist Systematic Strategies, LLC | 49,303 | $187.0 萬 | 0.02% | +23,153+88.5% | 加碼 |
| Barclays PLC | 45,962 | $174.3 萬 | 0.00% | +464+1.0% | 加碼 |
| Swiss National Bank | 39,100 | $148.3 萬 | 0.00% | +39,100 | 新進 |
| Bank of America Corp | 36,332 | $137.8 萬 | 0.00% | +36,332 | 新進 |
| Schonfeld Strategic Advisors LLC | 35,500 | $134.7 萬 | 0.01% | +35,500 | 新進 |
| NBW Capital LLC | 34,360 | $130.3 萬 | 0.27% | +34,360 | 新進 |
| Balyasny Asset Management LLC | 32,397 | $122.9 萬 | 0.00% | +32,397 | 新進 |
| Allianz Asset Management GmbH | 31,800 | $120.6 萬 | 0.00% | +31,800 | 新進 |
| Citigroup Inc | 31,757 | $120.5 萬 | 0.00% | +21,460+208.4% | 加碼 |
| Soros Fund Management LLC大師索羅斯基金管理 | 30,038 | $113.9 萬 | 0.03% | +30,038 | 新進 |
| Manufacturers Life Insurance Company, The | 24,657 | $93.5 萬 | 0.00% | +24,657 | 新進 |
| ExodusPoint Capital Management, LP | 24,472 | $92.8 萬 | 0.01% | −1,738−6.6% | 減碼 |
| Jump Financial, LLC | 22,800 | $86.5 萬 | 0.02% | +22,800 | 新進 |
| Credit Suisse AG | 22,056 | $83.7 萬 | 0.00% | +22,056 | 新進 |
| Blackstone Group Inc. | 19,991 | $75.8 萬 | 0.00% | 00.0% | 不變 |
| Global Endowment Management, LP | 18,184 | $69.0 萬 | 0.07% | −495,252−96.5% | 減碼 |
| Fred Alger Management, LLC | 18,158 | $68.9 萬 | 0.00% | +18,158 | 新進 |
| EAM Investors, LLC | 17,938 | $68.0 萬 | 0.11% | +17,938 | 新進 |
| California State Teachers Retirement System | 17,803 | $67.5 萬 | 0.00% | +17,803 | 新進 |
| Legal & General Group Plc | 17,032 | $64.6 萬 | 0.00% | +17,032 | 新進 |
| Virtu Financial LLC | 16,213 | $61.5 萬 | 0.05% | +16,213 | 新進 |
| Engineers Gate Manager LP | 15,653 | $59.4 萬 | 0.02% | +15,653 | 新進 |
| Charles Schwab Investment Management Inc | 15,000 | $56.9 萬 | 0.00% | +15,000 | 新進 |
| New York State Common Retirement Fund | 14,670 | $55.6 萬 | 0.00% | +14,305+3,919.2% | 加碼 |
| State of Wisconsin Investment Board | 14,632 | $55.5 萬 | 0.00% | +14,632 | 新進 |
| Janus Henderson Group PLC | 13,977 | $53.0 萬 | 0.00% | +13,977 | 新進 |
| Two Sigma Investments, LP | 13,355 | $50.7 萬 | 0.00% | −14,740−52.5% | 減碼 |
| Scientech Research LLC | 13,143 | $49.9 萬 | 0.26% | +13,143 | 新進 |
| Legato Capital Management LLC | 11,458 | $43.5 萬 | 0.05% | +11,458 | 新進 |
| EFG Asset Management (North America) Corp. | 11,151 | $42.3 萬 | 0.07% | +11,151 | 新進 |
| LMR Partners LLP | 11,093 | $42.1 萬 | 0.01% | +11,093 | 新進 |
| Polymer Capital Management (HK) LTD | 10,520 | $39.9 萬 | 0.10% | +10,520 | 新進 |
| Carlyle Group Inc. | 9,620 | $36.5 萬 | 0.02% | 00.0% | 不變 |
| Squarepoint Ops LLC | 8,161 | $31.0 萬 | 0.00% | +8,161 | 新進 |
| Susquehanna Fundamental Investments, LLC | 8,075 | $30.6 萬 | 0.01% | +8,075 | 新進 |
| Jane Street Group, LLC | 7,210 | $27.3 萬 | 0.00% | +7,210 | 新進 |
| Chartwell Investment Partners, LLC | 6,835 | $25.9 萬 | 0.01% | +6,835 | 新進 |
| Bank of New York Mellon Corp | 6,050 | $22.9 萬 | 0.00% | +6,050 | 新進 |
| Virtus ETF Advisers LLC | 5,838 | $22.1 萬 | 0.12% | −401−6.4% | 減碼 |
| Arizona State Retirement System | 5,445 | $20.7 萬 | 0.00% | +5,445 | 新進 |
| Tower Research Capital LLC (TRC) | 3,828 | $14.5 萬 | 0.00% | +1,248+48.4% | 加碼 |
| UBS Group AG | 2,601 | $9.87 萬 | 0.00% | −1,125−30.2% | 減碼 |
| Wells Fargo & Company | 2,242 | $8.50 萬 | 0.00% | +2,219+9,647.8% | 加碼 |
| Deutsche Bank AG | 298 | $1.13 萬 | 0.00% | +298 | 新進 |
| IFP Advisors, Inc | 114 | $4,324 | 0.00% | 00.0% | 不變 |
| Advisor Group Holdings, Inc. | 83 | $3,147 | 0.00% | −200−70.7% | 減碼 |
| Royal Bank of Canada | 56 | $2,000 | 0.00% | +56 | 新進 |
| Point72 (DIFC) Ltd | 22 | $847 | 0.00% | +22 | 新進 |