Spyre Therapeutics, Inc.
SYRE- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
近 90 天，Spyre Therapeutics, Inc. 內部人申報 0 筆公開市場買進、9 筆賣出；2026 年第 2 季末有 265 家機構在 13F 申報持有，市值合計 $85.2 億；沒有大師持有。
2021 年第 3 季 13F 持有人
Spyre Therapeutics, Inc. 在 2021/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 77
- 較 2021 年第 2 季 0 家
- 持有股數
- 4,058 萬
- 較 2021 年第 2 季 +204.1 萬 (+5.3%)
- 總市值
- $3.22 億
- 較 2021 年第 2 季 +$5,429 萬 (+20.2%)
- 新進機構
- 10
- 另有 24 家加碼
- 清倉機構
- 10
- 另有 23 家減碼
另有 1 家機構在 2021 年第 2 季持有、還沒有申報 2021 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 SYRE 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 265 | $85.2 億 |
| 2026 年第 1 季 | 198 | $41.6 億 |
| 2025 年第 4 季 | 153 | $26.5 億 |
| 2025 年第 3 季 | 137 | $10.8 億 |
| 2025 年第 2 季 | 129 | $9.53 億 |
| 2025 年第 1 季 | 129 | $10.0 億 |
| 2024 年第 4 季 | 131 | $13.9 億 |
| 2024 年第 3 季 | 119 | $15.1 億 |
| 2024 年第 2 季 | 107 | $11.8 億 |
| 2024 年第 1 季 | 103 | $12.1 億 |
| 2023 年第 4 季 | 54 | $6.01 億 |
| 2023 年第 3 季 | 29 | $4,387 萬 |
| 2023 年第 2 季 | 44 | $3,194 萬 |
| 2023 年第 1 季 | 45 | $1,198 萬 |
| 2022 年第 4 季 | 51 | $1,919 萬 |
| 2022 年第 3 季 | 55 | $2,352 萬 |
| 2022 年第 2 季 | 67 | $2,481 萬 |
| 2022 年第 1 季 | 84 | $9,538 萬 |
| 2021 年第 4 季 | 86 | $1.89 億 |
| 2021 年第 3 季 | 77 | $3.22 億 |
| 2021 年第 2 季 | 78 | $2.86 億 |
| 2021 年第 1 季 | 84 | $3.29 億 |
2021 年第 3 季持有機構
每家機構持有 Spyre Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2021 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 4,015,524 | $3,192 萬 | 0.35% | 00.0% | 不變 |
| Adage Capital Partners GP, L.L.C. | 3,500,000 | $2,783 萬 | 0.05% | +450,419+14.8% | 加碼 |
| Baker Bros. Advisors LP | 3,410,106 | $2,711 萬 | 0.12% | 00.0% | 不變 |
| BlackRock Inc. | 2,983,895 | $2,372 萬 | 0.00% | −119,984−3.9% | 減碼 |
| Bain Capital Life Sciences Investors, LLC | 2,847,689 | $2,264 萬 | 1.40% | +147,689+5.5% | 加碼 |
| Pictet Asset Management SA | 2,532,799 | $2,014 萬 | 0.02% | +2,532,799 | 新進 |
| Suvretta Capital Management, LLC | 2,157,727 | $1,715 萬 | 0.29% | +63,627+3.0% | 加碼 |
| Vanguard Group Inc | 2,108,760 | $1,677 萬 | 0.00% | +11,594+0.6% | 加碼 |
| Aisling Capital Management LP | 1,691,151 | $1,345 萬 | 2.68% | 00.0% | 不變 |
| Rock Springs Capital Management LP | 1,577,296 | $1,254 萬 | 0.26% | 00.0% | 不變 |
| Nantahala Capital Management, LLC | 1,516,955 | $1,206 萬 | 0.71% | −160,081−9.5% | 減碼 |
| Goldman Sachs Group Inc | 1,136,050 | $903.1 萬 | 0.00% | +4,991+0.4% | 加碼 |
| Artal Group S.A. | 1,045,000 | $830.8 萬 | 0.20% | 00.0% | 不變 |
| Great Point Partners LLC | 900,000 | $715.5 萬 | 1.69% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 883,720 | $702.6 萬 | 1.17% | 00.0% | 不變 |
| State Street Corp | 766,941 | $609.7 萬 | 0.00% | +9,441+1.2% | 加碼 |
| Geode Capital Management, LLC | 689,997 | $548.5 萬 | 0.00% | +12,271+1.8% | 加碼 |
| Dimensional Fund Advisors LP | 632,833 | $503.0 萬 | 0.00% | +28,721+4.8% | 加碼 |
| Altium Capital Management LP | 609,689 | $484.7 萬 | 1.29% | 00.0% | 不變 |
| Laurion Capital Management LP | 606,638 | $482.3 萬 | 0.07% | +606,638 | 新進 |
| Millennium Management LLC | 535,222 | $425.5 萬 | 0.01% | −7,963−1.5% | 減碼 |
| Sio Capital Management, LLC | 446,000 | $354.6 萬 | 1.14% | +43,347+10.8% | 加碼 |
| AXA S.A. | 439,667 | $349.5 萬 | 0.01% | +15,315+3.6% | 加碼 |
| Northern Trust Corp | 365,703 | $290.7 萬 | 0.00% | −2,637−0.7% | 減碼 |
| Marshall Wace, LLP | 315,823 | $251.1 萬 | 0.01% | −335,580−51.5% | 減碼 |
| Lion Point Capital, LP | 300,000 | $238.5 萬 | 0.63% | 00.0% | 不變 |
| Assenagon Asset Management S.A. | 267,066 | $212.3 萬 | 0.01% | −15,002−5.3% | 減碼 |
| University of Texas/Texas Am Investment Managment Co | 245,678 | $195.3 萬 | 1.12% | −23,900−8.9% | 減碼 |
| Abingworth LLP | 240,500 | $191.2 萬 | 0.43% | 00.0% | 不變 |
| Morgan Stanley | 194,225 | $154.4 萬 | 0.00% | −1,310−0.7% | 減碼 |
| Nuveen Asset Management, LLC | 179,642 | $134.2 萬 | 0.00% | −4,629−2.5% | 減碼 |
| Bank of New York Mellon Corp | 159,488 | $126.8 萬 | 0.00% | +12,087+8.2% | 加碼 |
| Fan Yu | 112,044 | $89.1 萬 | 15.31% | 00.0% | 不變 |
| AlphaCentric Advisors LLC | 110,000 | $87.5 萬 | 0.22% | +17,500+18.9% | 加碼 |
| Franklin Street Advisors Inc | 103,600 | $82.4 萬 | 0.07% | 00.0% | 不變 |
| Renaissance Technologies LLC | 100,300 | $79.7 萬 | 0.00% | +49,513+97.5% | 加碼 |
| Charles Schwab Investment Management Inc | 99,477 | $79.1 萬 | 0.00% | −6,302−6.0% | 減碼 |
| Ritholtz Wealth Management | 76,490 | $60.8 萬 | 0.04% | −98,156−56.2% | 減碼 |
| UBS Group AG | 54,220 | $43.1 萬 | 0.00% | +2,143+4.1% | 加碼 |
| Rhumbline Advisers | 54,143 | $43.0 萬 | 0.00% | +1,476+2.8% | 加碼 |
| Blair William & Co | 52,204 | $41.5 萬 | 0.00% | 00.0% | 不變 |
| Parametric Portfolio Associates LLC | 45,106 | $35.9 萬 | 0.00% | +11,958+36.1% | 加碼 |
| Algert Global LLC | 36,804 | $29.3 萬 | 0.04% | −4,696−11.3% | 減碼 |
| D. E. Shaw & Co., Inc. | 28,503 | $22.7 萬 | 0.00% | −17,478−38.0% | 減碼 |
| SG Americas Securities, LLC | 28,578 | $22.7 萬 | 0.00% | +28,578 | 新進 |
| Alliancebernstein L.P. | 25,600 | $20.4 萬 | 0.00% | 00.0% | 不變 |
| Bank of America Corp | 25,639 | $20.4 萬 | 0.00% | +5,423+26.8% | 加碼 |
| Manufacturers Life Insurance Company, The | 25,323 | $20.1 萬 | 0.00% | −1,200−4.5% | 減碼 |
| Deutsche Bank AG | 23,243 | $18.5 萬 | 0.00% | −750−3.1% | 減碼 |
| American International Group, Inc. | 22,120 | $17.6 萬 | 0.00% | −525−2.3% | 減碼 |
| California State Teachers Retirement System | 21,698 | $17.2 萬 | 0.00% | −34,163−61.2% | 減碼 |
| Voya Investment Management LLC | 19,878 | $15.8 萬 | 0.00% | 00.0% | 不變 |
| JPMorgan Chase & Co | 19,187 | $15.2 萬 | 0.00% | −68,446−78.1% | 減碼 |
| New York State Common Retirement Fund | 17,079 | $13.6 萬 | 0.00% | −14,405−45.8% | 減碼 |
| Barclays PLC | 16,524 | $13.1 萬 | 0.00% | +10,856+191.5% | 加碼 |
| ProShare Advisors LLC | 15,658 | $12.4 萬 | 0.00% | −3,635−18.8% | 減碼 |
| MetLife Investment Management | 15,353 | $12.2 萬 | 0.00% | +15,353 | 新進 |
| Invesco Ltd. | 14,726 | $11.7 萬 | 0.00% | +1,681+12.9% | 加碼 |
| HighVista Strategies LLC | 13,137 | $10.5 萬 | 0.07% | +13,137 | 新進 |
| Metropolitan Life Insurance Co | 11,616 | $9.23 萬 | 0.00% | +11,616 | 新進 |
| Gsa Capital Partners LLP | 11,242 | $8.90 萬 | 0.01% | +11,242 | 新進 |
| Susquehanna International Group, LLP | 11,192 | $8.90 萬 | 0.00% | +11,192 | 新進 |
| Personal Cfo Solutions, LLC | 10,888 | $8.70 萬 | 0.02% | −500−4.4% | 減碼 |
| BNP Paribas Arbitrage, SA | 10,756 | $8.55 萬 | 0.00% | +6,051+128.6% | 加碼 |
| Lazard Asset Management LLC | 8,801 | $6.90 萬 | 0.00% | +8,801 | 新進 |
| Citigroup Inc | 7,133 | $5.70 萬 | 0.00% | +2,150+43.1% | 加碼 |
| Royal Bank of Canada | 5,468 | $4.40 萬 | 0.00% | +2,502+84.4% | 加碼 |
| Ameritas Investment Partners, Inc. | 3,710 | $2.90 萬 | 0.00% | 00.0% | 不變 |
| Legal & General Group Plc | 3,264 | $2.60 萬 | 0.00% | 00.0% | 不變 |
| Tower Research Capital LLC (TRC) | 3,250 | $2.60 萬 | 0.00% | +229+7.6% | 加碼 |
| IFP Advisors, Inc | 2,980 | $2.40 萬 | 0.00% | −1,000−25.1% | 減碼 |
| Russell Investments Group, Ltd. | 3,008 | $2.30 萬 | 0.00% | −21,027−87.5% | 減碼 |
| Wells Fargo & Company | 2,212 | $1.80 萬 | 0.00% | 00.0% | 不變 |
| Quadrant Capital Group LLC | 1,137 | $9,000 | 0.00% | 00.0% | 不變 |
| Penserra Capital Management LLC | 1,120 | $8,000 | 0.00% | +5+0.4% | 加碼 |
| Daiwa Securities Group Inc. | 98 | $1,000 | 0.00% | 00.0% | 不變 |
| Berman Capital Advisors, LLC | 56 | $0 | 0.00% | +56 | 新進 |
| Boxer Capital, LLC | 0 | $0 | 0.00% | −550,000−100.0% | 清倉 |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −469,765−100.0% | 清倉 |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −59,294−100.0% | 清倉 |
| Ergoteles LLC | 0 | $0 | 0.00% | −34,100−100.0% | 清倉 |
| California Public Employees Retirement System | 0 | $0 | 0.00% | −20,841−100.0% | 清倉 |
| Cerity Partners LLC | 0 | $0 | 0.00% | −18,000−100.0% | 清倉 |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −11,722−100.0% | 清倉 |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −1,654−100.0% | 清倉 |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −300−100.0% | 清倉 |
| Ellevest, Inc. | 0 | $0 | 0.00% | −150−100.0% | 清倉 |
| Pictet Asset Management Ltd | – | – | – | – | 本季未申報 |