Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Tyra Biosciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 116
- −5 vs. Q2 2025
- Shares held
- 55.6M
- −950.0K (−1.7%) vs. Q2 2025
- Total value
- $778.4M
- +$236.9M (+43.7%) vs. Q2 2025
- New holders
- 9
- 40 more added
- Sold out
- 14
- 38 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 5 | $70 | 0.00% | +1+25.0% | Added |
| Farther Finance Advisors, LLC | 11 | $154 | 0.00% | +11 | New |
| Signaturefd, LLC | 43 | $602 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 44 | $616 | 0.00% | +4+10.0% | Added |
| Rise Advisors, LLC | 49 | $686 | 0.00% | +49 | New |
| Rothschild Investment LLC | 55 | $769 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 85 | $1.19K | 0.00% | +85 | New |
| Nisa Investment Advisors, LLC | 86 | $1.20K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 100 | $1.40K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 125 | $1.75K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 138 | $1.93K | 0.00% | +102+283.3% | Added |
| True Wealth Design, LLC | 142 | $1.99K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 173 | $2.00K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 208 | $2.91K | 0.00% | +150+258.6% | Added |
| GAMMA Investing LLC | 311 | $4.35K | 0.00% | +96+44.7% | Added |
| Optiver Holding B.V. | 368 | $5.15K | 0.00% | +368 | New |
| STRS Ohio | 700 | $9.79K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 701 | $10.0K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 819 | $11.5K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 874 | $12.2K | 0.00% | −1,966−69.2% | Reduced |
| Royal Bank of Canada | 1,156 | $16.0K | 0.00% | −15,057−92.9% | Reduced |
| GF Fund Management Co. Ltd. | 1,147 | $16.0K | 0.00% | −149−11.5% | Reduced |
| Advisor Group Holdings, Inc. | 1,192 | $16.1K | 0.00% | +183+18.1% | Added |
| California State Teachers Retirement System | 1,473 | $20.6K | 0.00% | +1+0.1% | Added |
| CWM, LLC | 1,529 | $21.0K | 0.00% | −12−0.8% | Reduced |
| Sterling Capital Management LLC | 1,662 | $23.3K | 0.00% | +1,012+155.7% | Added |
| Citigroup Inc | 1,707 | $23.9K | 0.00% | −7,790−82.0% | Reduced |
| Ameritas Investment Partners, Inc. | 1,991 | $27.9K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,060 | $28.8K | 0.00% | +6+0.3% | Added |
| Federated Hermes, Inc. | 2,155 | $30.1K | 0.00% | +1,841+586.3% | Added |
| Legal & General Group Plc | 2,192 | $30.7K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 6,440 | $90.1K | 0.00% | +1,391+27.6% | Added |
| New York State Common Retirement Fund | 7,423 | $103.8K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 9,342 | $130.7K | 0.01% | −1,339−12.5% | Reduced |
| SG Americas Securities, LLC | 9,542 | $133.0K | 0.00% | +9,542 | New |
| Baker Bros. Advisors LP | 10,607 | $148.4K | 0.00% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 10,761 | $150.5K | 0.00% | −15,504−59.0% | Reduced |
| Virtus Investment Advisers, Inc. | 11,015 | $154.1K | 0.04% | +1,912+21.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 11,317 | $158.3K | 0.00% | −1,865−14.1% | Reduced |
| Intech Investment Management LLC | 11,402 | $159.5K | 0.00% | −8,517−42.8% | Reduced |
| Squarepoint Ops LLC | 12,214 | $170.9K | 0.00% | −19,194−61.1% | Reduced |
| FMR LLC | 12,529 | $175.3K | 0.00% | +327+2.7% | Added |
| Russell Investments Group, Ltd. | 12,741 | $178.2K | 0.00% | +2,766+27.7% | Added |
| Price T Rowe Associates Inc | 12,801 | $180.0K | 0.00% | +779+6.5% | Added |
| MetLife Investment Management | 14,631 | $204.7K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 15,483 | $216.6K | 0.00% | +2,183+16.4% | Added |
| Invesco Ltd. | 15,510 | $217.0K | 0.00% | +15,510 | New |
| Trexquant Investment LP | 15,758 | $220.5K | 0.00% | −28,923−64.7% | Reduced |
| Wells Fargo & Company | 18,470 | $258.4K | 0.00% | +3,013+19.5% | Added |
| Victory Capital Management Inc | 18,790 | $262.9K | 0.00% | −25,400−57.5% | Reduced |
| Auour Investments LLC | 21,020 | $294.1K | 0.10% | 00.0% | Unchanged |
| Alps Advisors Inc | 24,700 | $345.6K | 0.00% | −4,029−14.0% | Reduced |
| Public Employees Retirement System of Ohio | 24,962 | $349.2K | 0.00% | +6,450+34.8% | Added |
| AQR Capital Management LLC | 28,069 | $392.7K | 0.00% | −643−2.2% | Reduced |
| State of Wisconsin Investment Board | 29,648 | $414.8K | 0.00% | −46,801−61.2% | Reduced |
| Quest Partners LLC | 30,060 | $420.5K | 0.03% | −43,013−58.9% | Reduced |
| Brevan Howard Capital Management LP | 31,101 | $435.1K | 0.01% | −5,493−15.0% | Reduced |
| Alliancebernstein L.P. | 33,260 | $465.3K | 0.00% | −2,380−6.7% | Reduced |
| XTX Topco Ltd | 33,700 | $471.5K | 0.02% | −901−2.6% | Reduced |
| American Century Companies Inc | 38,412 | $537.4K | 0.00% | +9,558+33.1% | Added |
| Cubist Systematic Strategies, LLC | 39,310 | $549.9K | 0.01% | −82,726−67.8% | Reduced |
| Dimensional Fund Advisors LP | 39,679 | $555.1K | 0.00% | −2,002−4.8% | Reduced |
| Rhumbline Advisers | 40,636 | $568.5K | 0.00% | −49−0.1% | Reduced |
| PDT Partners, LLC | 43,310 | $605.9K | 0.04% | 00.0% | Unchanged |
| Jane Street Group, LLC | 44,680 | $625.1K | 0.00% | −13,488−23.2% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 48,644 | $680.5K | 0.01% | 00.0% | Unchanged |
| Barclays PLC | 57,126 | $799.2K | 0.00% | −4,429−7.2% | Reduced |
| Bank of New York Mellon Corp | 57,162 | $799.7K | 0.00% | +3,123+5.8% | Added |
| UBS Group AG | 59,144 | $827.4K | 0.00% | +12,876+27.8% | Added |
| Jump Financial, LLC | 62,000 | $867.4K | 0.01% | −9,119−12.8% | Reduced |
| HighVista Strategies LLC | 65,812 | $920.7K | 0.23% | +40,850+163.6% | Added |
| JPMorgan Chase & Co | 74,229 | $1.04M | 0.00% | −28,688−27.9% | Reduced |
| Nuveen, LLC | 80,441 | $1.13M | 0.00% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 82,238 | $1.15M | 0.01% | +8,205+11.1% | Added |
| Wellington Management Group LLP | 82,871 | $1.16M | 0.00% | −20,207−19.6% | Reduced |
| Investment Counsel Co of Nevada | 85,020 | $1.19M | 2.42% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 87,107 | $1.22M | 0.00% | +6,505+8.1% | Added |
| Goldman Sachs Group Inc | 100,150 | $1.40M | 0.00% | −5,445−5.2% | Reduced |
| Citadel Advisors LLC | 111,293 | $1.56M | 0.00% | −104,843−48.5% | Reduced |
| Two Sigma Advisers, LP | 113,200 | $1.58M | 0.00% | +26,200+30.1% | Added |
| Raymond James Financial Inc | 126,374 | $1.77M | 0.00% | +63,187+100.0% | Added |
| AXA Investment Managers S.A. | 128,789 | $1.80M | 0.00% | +128,789 | New |
| BNP Paribas Arbitrage, SA | 128,881 | $1.80M | 0.00% | +31,145+31.9% | Added |
| Bank of America Corp | 134,319 | $1.88M | 0.00% | −238,648−64.0% | Reduced |
| Millennium Management LLC | 144,016 | $2.01M | 0.00% | −263,448−64.7% | Reduced |
| Renaissance Technologies LLC | 170,100 | $2.38M | 0.00% | +35,000+25.9% | Added |
| Boothbay Fund Management, LLC | 186,670 | $2.61M | 0.07% | +186,670 | New |
| Two Sigma Investments, LP | 199,438 | $2.79M | 0.00% | +93,613+88.5% | Added |
| Charles Schwab Investment Management Inc | 201,587 | $2.82M | 0.00% | +23,483+13.2% | Added |
| Northern Trust Corp | 208,486 | $2.92M | 0.00% | +3,178+1.5% | Added |
| Jacobs Levy Equity Management, Inc | 251,562 | $3.52M | 0.01% | −143,737−36.4% | Reduced |
| Eversept Partners, LP | 272,706 | $3.82M | 0.29% | +272,706 | New |
| Point72 Asset Management, L.P. | 282,032 | $3.95M | 0.01% | +57,332+25.5% | Added |
| Walleye Capital LLC | 297,808 | $4.17M | 0.03% | −72,600−19.6% | Reduced |
| Morgan Stanley | 322,143 | $4.51M | 0.00% | −56,259−14.9% | Reduced |
| State Street Corp | 428,472 | $5.99M | 0.00% | +9,488+2.3% | Added |
| Sio Capital Management, LLC | 514,947 | $7.20M | 1.82% | −295,327−36.4% | Reduced |
| Geode Capital Management, LLC | 597,454 | $8.36M | 0.00% | +30,328+5.3% | Added |
| Marshall Wace, LLP | 602,015 | $8.42M | 0.01% | +173,907+40.6% | Added |