Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Tyra Biosciences, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 113
- +18 vs. Q3 2024
- Shares held
- 48.6M
- +1.56M (+3.3%) vs. Q3 2024
- Total value
- $675.8M
- −$430.2M (−38.9%) vs. Q3 2024
- New holders
- 36
- 34 more added
- Sold out
- 18
- 25 more reduced
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 2 | $28 | 0.00% | +2 | New |
| Rothschild Investment LLC | 5 | $70 | 0.00% | −10−66.7% | Reduced |
| CoreCap Advisors, LLC | 16 | $222 | 0.00% | +16 | New |
| SBI Securities Co., Ltd. | 19 | $264 | 0.00% | +19 | New |
| Sterling Capital Management LLC | 21 | $292 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 22 | $306 | 0.00% | −183−89.3% | Reduced |
| Nisa Investment Advisors, LLC | 23 | $320 | 0.00% | −17−42.5% | Reduced |
| Signaturefd, LLC | 24 | $334 | 0.00% | +24 | New |
| GAMMA Investing LLC | 26 | $361 | 0.00% | −57−68.7% | Reduced |
| The PNC Financial Services Group, Inc. | 58 | $806 | 0.00% | 00.0% | Unchanged |
| Creative Planning | 63 | $876 | 0.00% | +63 | New |
| CWM, LLC | 71 | $1.00K | 0.00% | +49+222.7% | Added |
| Aster Capital Management (DIFC) Ltd | 214 | $2.98K | 0.00% | +214 | New |
| Amalgamated Bank | 424 | $6.00K | 0.00% | 00.0% | Unchanged |
| Point72 (DIFC) Ltd | 561 | $7.79K | 0.00% | +561 | New |
| STRS Ohio | 700 | $9.73K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 774 | $11.0K | 0.00% | −1,361−63.7% | Reduced |
| Federated Hermes, Inc. | 1,028 | $14.3K | 0.00% | +98+10.5% | Added |
| GF Fund Management Co. Ltd. | 1,063 | $14.8K | 0.00% | +1,063 | New |
| Tower Research Capital LLC (TRC) | 1,417 | $19.7K | 0.00% | +206+17.0% | Added |
| R Squared Ltd | 1,480 | $20.6K | 0.02% | +1,480 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,686 | $23.7K | 0.00% | +1,686 | New |
| Ameritas Investment Partners, Inc. | 1,991 | $27.7K | 0.00% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 2,200 | $30.6K | 0.00% | +2,200 | New |
| US Bancorp | 3,612 | $50.2K | 0.00% | +3,612 | New |
| BNP Paribas Arbitrage, SA | 4,318 | $60.0K | 0.00% | +4,318 | New |
| Aquatic Capital Management LLC | 4,586 | $63.7K | 0.00% | +4,586 | New |
| Virtus ETF Advisers LLC | 4,686 | $65.1K | 0.03% | +44+0.9% | Added |
| Quest Partners LLC | 5,023 | $69.8K | 0.01% | −15,855−75.9% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 5,049 | $70.2K | 0.00% | +5,049 | New |
| New York State Common Retirement Fund | 7,423 | $103.2K | 0.00% | 00.0% | Unchanged |
| Exchange Traded Concepts, LLC | 8,311 | $115.5K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 9,340 | $129.8K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 9,493 | $132.0K | 0.00% | +3,236+51.7% | Added |
| SG Americas Securities, LLC | 9,671 | $134.0K | 0.00% | −3,540−26.8% | Reduced |
| Corebridge Financial, Inc. | 10,102 | $140.4K | 0.00% | −762−7.0% | Reduced |
| Russell Investments Group, Ltd. | 10,455 | $145.3K | 0.00% | +10,447+130,587.5% | Added |
| California State Teachers Retirement System | 10,570 | $146.9K | 0.00% | −2,366−18.3% | Reduced |
| Baker Bros. Advisors LP | 10,607 | $147.4K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 10,730 | $149.1K | 0.01% | +10,730 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 11,641 | $161.8K | 0.00% | +532+4.8% | Added |
| MetLife Investment Management | 12,207 | $169.7K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 12,300 | $171.0K | 0.00% | +12,300 | New |
| Franklin Resources Inc | 12,751 | $177.2K | 0.00% | +104+0.8% | Added |
| Point72 Asset Management, L.P. | 12,783 | $177.7K | 0.00% | +12,783 | New |
| Manufacturers Life Insurance Company, The | 13,368 | $185.8K | 0.00% | −816−5.8% | Reduced |
| Jump Financial, LLC | 15,160 | $210.7K | 0.00% | +15,160 | New |
| Tudor Investment Corp Et Al | 15,577 | $216.5K | 0.00% | −10,769−40.9% | Reduced |
| Citigroup Inc | 16,803 | $233.6K | 0.00% | +2,136+14.6% | Added |
| Boothbay Fund Management, LLC | 17,560 | $244.1K | 0.01% | +17,560 | New |
| Alliancebernstein L.P. | 17,570 | $244.2K | 0.00% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 18,209 | $253.1K | 0.11% | +18,209 | New |
| Squarepoint Ops LLC | 18,216 | $253.2K | 0.00% | +18,216 | New |
| Deutsche Bank AG | 18,909 | $262.8K | 0.00% | +6,466+52.0% | Added |
| PDT Partners, LLC | 20,359 | $283.0K | 0.03% | +20,359 | New |
| Swiss National Bank | 20,700 | $287.7K | 0.00% | −5,000−19.5% | Reduced |
| Auour Investments LLC | 21,020 | $303.9K | 0.11% | 00.0% | Unchanged |
| American Century Companies Inc | 22,142 | $307.8K | 0.00% | −20,857−48.5% | Reduced |
| HighVista Strategies LLC | 23,941 | $332.8K | 0.12% | +7,863+48.9% | Added |
| Rhumbline Advisers | 26,202 | $364.2K | 0.00% | +1,027+4.1% | Added |
| Renaissance Technologies LLC | 29,100 | $404.5K | 0.00% | +29,100 | New |
| UBS Asset Management Americas Inc | 35,635 | $495.3K | 0.00% | +10,426+41.4% | Added |
| Dimensional Fund Advisors LP | 37,981 | $527.9K | 0.00% | +28,074+283.4% | Added |
| Susquehanna Fundamental Investments, LLC | 39,093 | $543.4K | 0.01% | +39,093 | New |
| Barclays PLC | 43,070 | $598.7K | 0.00% | +5,445+14.5% | Added |
| Bank of New York Mellon Corp | 45,007 | $625.6K | 0.00% | +2,221+5.2% | Added |
| Two Sigma Investments, LP | 46,269 | $643.1K | 0.00% | +7,093+18.1% | Added |
| UBS Group AG | 47,851 | $665.1K | 0.00% | +36,887+336.4% | Added |
| Nuveen Asset Management, LLC | 49,998 | $695.0K | 0.00% | 00.0% | Unchanged |
| Marshall Wace, LLP | 54,077 | $751.7K | 0.00% | +34,463+175.7% | Added |
| Raymond James Financial Inc | 54,783 | $761.5K | 0.00% | +54,783 | New |
| Citadel Advisors LLC | 55,587 | $772.7K | 0.00% | +31,635+132.1% | Added |
| Victory Capital Management Inc | 56,640 | $787.3K | 0.00% | +26,560+88.3% | Added |
| Ikarian Capital, LLC | 60,000 | $834.0K | 0.24% | +60,000 | New |
| Walleye Capital LLC | 62,980 | $875.4K | 0.01% | −63,617−50.3% | Reduced |
| Goldman Sachs Group Inc | 64,110 | $891.1K | 0.00% | −24,971−28.0% | Reduced |
| State of Wisconsin Investment Board | 65,039 | $904.0K | 0.00% | +29,473+82.9% | Added |
| Bank of America Corp | 66,157 | $919.6K | 0.00% | +11,804+21.7% | Added |
| Morgan Stanley | 74,149 | $1.03M | 0.00% | +5,233+7.6% | Added |
| Oppenheimer & Co Inc | 75,439 | $1.05M | 0.02% | −1,367−1.8% | Reduced |
| Investment Counsel Co of Nevada | 85,020 | $1.18M | 3.00% | +85,020 | New |
| JPMorgan Chase & Co | 91,115 | $1.27M | 0.00% | −277,532−75.3% | Reduced |
| Wellington Management Group LLP | 94,859 | $1.32M | 0.00% | +4,034+4.4% | Added |
| Nantahala Capital Management, LLC | 100,000 | $1.39M | 0.10% | +100,000 | New |
| Cubist Systematic Strategies, LLC | 109,748 | $1.53M | 0.02% | +109,748 | New |
| Polar Asset Management Partners Inc. | 111,107 | $1.54M | 0.02% | +23,007+26.1% | Added |
| Charles Schwab Investment Management Inc | 170,600 | $2.37M | 0.00% | −3,137−1.8% | Reduced |
| Ally Bridge Group (NY) LLC | 175,063 | $2.43M | 2.09% | −95,012−35.2% | Reduced |
| Adage Capital Partners GP, L.L.C. | 200,000 | $2.78M | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 222,764 | $3.10M | 0.00% | +8,411+3.9% | Added |
| Sio Capital Management, LLC | 240,870 | $3.35M | 0.94% | −160,000−39.9% | Reduced |
| Jacobs Levy Equity Management, Inc | 244,245 | $3.40M | 0.01% | +244,245 | New |
| Millennium Management LLC | 315,141 | $4.38M | 0.00% | +304,637+2,900.2% | Added |
| Pictet Asset Management Holding SA | 354,012 | $4.92M | 0.01% | +354,012 | New |
| State Street Corp | 407,573 | $5.67M | 0.00% | +22,841+5.9% | Added |
| Geode Capital Management, LLC | 517,578 | $7.20M | 0.00% | −5,612−1.1% | Reduced |
| Kynam Capital Management, LP | 530,478 | $7.37M | 0.49% | +62,531+13.4% | Added |
| 5AM Venture Management, LLC | 939,298 | $13.1M | 3.12% | 00.0% | Unchanged |
| Vestal Point Capital, LP | 990,000 | $13.8M | 0.82% | +990,000 | New |