Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 131
- +13 vs. Q3 2024
- Shares held
- 167.5M
- +12.6M (+8.2%) vs. Q3 2024
- Total value
- $289.8M
- −$21.5M (−6.9%) vs. Q3 2024
- New holders
- 28
- 44 more added
- Sold out
- 15
- 28 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 19,999,999 | $34.6M | 0.49% | +1,349,999+7.2% | Added |
| Morgan Stanley | 17,640,366 | $30.5M | 0.00% | +9,976,373+130.2% | Added |
| FMR LLC | 16,365,664 | $28.3M | 0.00% | −2,312,863−12.4% | Reduced |
| BlackRock, Inc. | 13,531,467 | $23.4M | 0.00% | +10,934+0.1% | Added |
| Ra Capital Management, L.P. | 10,872,503 | $18.8M | 0.25% | 00.0% | Unchanged |
| Octagon Capital Advisors LP | 10,450,000 | $18.1M | 3.08% | +5,877,778+128.6% | Added |
| Vanguard Group Inc | 8,906,764 | $15.4M | 0.00% | +641,305+7.8% | Added |
| RTW Investments, LP | 8,672,630 | $15.0M | 0.23% | −6,273,790−42.0% | Reduced |
| Siren, L.L.C. | 6,602,475 | $11.4M | 0.50% | +1,722,600+35.3% | Added |
| State Street Corp | 6,474,367 | $11.2M | 0.00% | +3,005,299+86.6% | Added |
| Adage Capital Partners GP, L.L.C. | 5,000,000 | $8.65M | 0.02% | +5,000,000 | New |
| Baker Bros. Advisors LP | 4,004,756 | $6.93M | 0.07% | 00.0% | Unchanged |
| Tybourne Capital Management (HK) Ltd | 3,700,000 | $6.40M | 1.61% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 3,572,349 | $6.18M | 0.00% | +9,591+0.3% | Added |
| VR Adviser, LLC | 3,225,180 | $5.58M | 0.38% | −5,774,820−64.2% | Reduced |
| Polar Capital Holdings Plc | 3,000,000 | $5.19M | 0.03% | −25,000−0.8% | Reduced |
| JPMorgan Chase & Co | 2,643,755 | $4.57M | 0.00% | −357,642−11.9% | Reduced |
| Bank of America Corp | 1,710,303 | $2.96M | 0.00% | +1,576,568+1,178.9% | Added |
| Granahan Investment Management Inc | 1,636,381 | $2.83M | 0.12% | +496,482+43.6% | Added |
| Norges Bank | 1,461,120 | $2.53M | 0.00% | +1,461,120 | New |
| Northern Trust Corp | 1,458,732 | $2.52M | 0.00% | +86,207+6.3% | Added |
| Woodline Partners LP | 1,027,522 | $1.78M | 0.01% | +280.0% | Added |
| Goldman Sachs Group Inc | 967,144 | $1.67M | 0.00% | −238,527−19.8% | Reduced |
| B Group, Inc. | 965,556 | $1.67M | 1.02% | +965,556 | New |
| Acuta Capital Partners, LLC | 884,244 | $1.53M | 1.54% | −1,234,748−58.3% | Reduced |
| Renaissance Technologies LLC | 878,448 | $1.52M | 0.00% | +878,448 | New |
| Palo Alto Investors LP | 811,268 | $1.40M | 0.22% | 00.0% | Unchanged |
| Quantum Private Wealth, LLC | 794,976 | $1.38M | 0.44% | +27,360+3.6% | Added |
| Citadel Advisors LLC | 745,205 | $1.29M | 0.00% | −2,114,767−73.9% | Reduced |
| Sands Capital Ventures, LLC | 724,873 | $1.25M | 0.27% | 00.0% | Unchanged |
| Alphabet Inc. | 640,882 | $1.11M | 0.06% | 00.0% | Unchanged |
| Wellington Management Group LLP | 585,594 | $1.01M | 0.00% | +122,402+26.4% | Added |
| Nuveen Asset Management, LLC | 546,414 | $945.3K | 0.00% | −20,436−3.6% | Reduced |
| DAFNA Capital Management LLC | 522,500 | $903.9K | 0.23% | +522,500 | New |
| Charles Schwab Investment Management Inc | 474,257 | $820.5K | 0.00% | +11,390+2.5% | Added |
| Bank of New York Mellon Corp | 450,261 | $779.0K | 0.00% | +111,989+33.1% | Added |
| UBS Group AG | 421,396 | $729.0K | 0.00% | +329,395+358.0% | Added |
| Barclays PLC | 335,238 | $586.7K | 0.00% | +87,958+35.6% | Added |
| Kovitz Investment Group Partners, LLC | 292,778 | $506.5K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 253,292 | $438.2K | 0.00% | +120,680+91.0% | Added |
| Rafferty Asset Management, LLC | 252,257 | $436.4K | 0.00% | +252,257 | New |
| Squarepoint Ops LLC | 211,842 | $366.5K | 0.00% | +108,719+105.4% | Added |
| Rhumbline Advisers | 192,079 | $332.3K | 0.00% | +5,831+3.1% | Added |
| ADAR1 Capital Management, LLC | 177,707 | $307.4K | 0.06% | −73,693−29.3% | Reduced |
| Jane Street Group, LLC | 169,575 | $293.4K | 0.00% | +62,003+57.6% | Added |
| Millennium Management LLC | 151,614 | $262.3K | 0.00% | +151,614 | New |
| Deutsche Bank AG | 151,083 | $261.4K | 0.00% | −2,409,201−94.1% | Reduced |
| Susquehanna International Group, LLP | 142,463 | $246.5K | 0.00% | −34,029−19.3% | Reduced |
| Marshall Wace, LLP | 138,111 | $238.9K | 0.00% | −347,915−71.6% | Reduced |
| Los Angeles Capital Management LLC | 137,460 | $237.8K | 0.00% | −69,532−33.6% | Reduced |
| Privium Fund Management B.V. | 134,900 | $233.4K | 0.05% | +14,900+12.4% | Added |
| Chicago Partners Investment Group LLC | 116,044 | $224.0K | 0.01% | −2,131−1.8% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 108,604 | $187.9K | 0.00% | +20,551+23.3% | Added |
| Alliancebernstein L.P. | 108,250 | $187.3K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 107,544 | $186.0K | 0.01% | +107,544 | New |
| Wells Fargo & Company | 103,384 | $178.9K | 0.00% | +31,457+43.7% | Added |
| Invesco Ltd. | 87,355 | $151.1K | 0.00% | +1,674+2.0% | Added |
| Corebridge Financial, Inc. | 87,150 | $150.8K | 0.00% | −4,948−5.4% | Reduced |
| Leonteq Securities AG | 79,999 | $138.4K | 0.01% | −10.0% | Reduced |
| Aquatic Capital Management LLC | 78,246 | $135.4K | 0.00% | +78,246 | New |
| Intech Investment Management LLC | 68,035 | $117.7K | 0.00% | +25,941+61.6% | Added |
| Price T Rowe Associates Inc | 65,331 | $114.0K | 0.00% | +5,612+9.4% | Added |
| Manufacturers Life Insurance Company, The | 63,011 | $109.0K | 0.00% | +2,346+3.9% | Added |
| MetLife Investment Management | 62,990 | $109.0K | 0.00% | −13,047−17.2% | Reduced |
| EntryPoint Capital, LLC | 61,495 | $106.4K | 0.04% | +34,468+127.5% | Added |
| LPL Financial LLC | 60,000 | $103.8K | 0.00% | +60,000 | New |
| ProShare Advisors LLC | 59,076 | $102.2K | 0.00% | +14,418+32.3% | Added |
| Commonwealth Equity Services, LLC | 59,069 | $102.0K | 0.00% | +31,000+110.4% | Added |
| Mariner, LLC | 58,342 | $100.9K | 0.00% | +45,006+337.5% | Added |
| Voya Investment Management LLC | 51,216 | $88.6K | 0.00% | −3,828−7.0% | Reduced |
| Tower Research Capital LLC (TRC) | 51,085 | $88.4K | 0.00% | +37,233+268.8% | Added |
| Profund Advisors LLC | 50,242 | $86.9K | 0.00% | +50,242 | New |
| Police & Firemen's Retirement System of New Jersey | 45,678 | $79.0K | 0.00% | +45,678 | New |
| Williams & Novak, LLC | 45,000 | $77.8K | 0.08% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 43,456 | $75.2K | 0.01% | +4,039+10.2% | Added |
| Engineers Gate Manager LP | 35,808 | $61.9K | 0.00% | +35,808 | New |
| Verition Fund Management LLC | 34,098 | $59.0K | 0.00% | +34,098 | New |
| Virtus ETF Advisers LLC | 31,597 | $54.7K | 0.02% | +9,494+43.0% | Added |
| First Manhattan Co | 28,500 | $49.3K | 0.00% | +28,500 | New |
| SG Americas Securities, LLC | 28,498 | $49.0K | 0.00% | −35,486−55.5% | Reduced |
| AQR Capital Management LLC | 25,354 | $43.9K | 0.00% | −44,117−63.5% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 23,490 | $41.0K | 0.00% | −15−0.1% | Reduced |
| BNP Paribas Arbitrage, SA | 23,644 | $40.9K | 0.00% | +23,644 | New |
| Ameriprise Financial Inc | 22,993 | $39.8K | 0.00% | +22,993 | New |
| Axq Capital, LP | 22,432 | $38.8K | 0.02% | +22,432 | New |
| New York State Common Retirement Fund | 21,100 | $36.5K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 20,788 | $36.0K | 0.00% | +6,670+47.2% | Added |
| HSBC Holdings PLC | 20,391 | $35.6K | 0.00% | +8,076+65.6% | Added |
| Legal & General Group Plc | 20,018 | $34.6K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 20,010 | $34.6K | 0.00% | 00.0% | Unchanged |
| Lee Financial Co | 20,000 | $34.6K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 19,001 | $32.9K | 0.00% | −1,006−5.0% | Reduced |
| E Fund Management Co., Ltd. | 17,844 | $30.9K | 0.00% | +17,844 | New |
| CIBC World Markets Corp | 16,405 | $28.4K | 0.00% | +16,405 | New |
| Ameritas Investment Partners, Inc. | 15,672 | $27.1K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 14,971 | $25.9K | 0.00% | −828−5.2% | Reduced |
| Ground Swell Capital, LLC | 14,660 | $25.4K | 0.06% | +14,660 | New |
| Howard Capital Management Inc. | 14,165 | $24.5K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 12,990 | $22.5K | 0.00% | +1,800+16.1% | Added |
| California State Teachers Retirement System | 12,635 | $21.9K | 0.00% | 00.0% | Unchanged |