Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.06B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 208
- +19 vs. Q1 2026
- Shares held
- 299.6M
- +34.0M (+12.8%) vs. Q1 2026
- Total value
- $2.06B
- +$853.2M (+70.8%) vs. Q1 2026
- New holders
- 41
- 99 more added
- Sold out
- 22
- 41 more reduced
2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.06B |
| Q1 2026 | 191 | $1.21B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $867.0M |
| Q2 2025 | 150 | $596.7M |
| Q1 2025 | 127 | $232.1M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 120 | $326.6M |
| Q2 2024 | 107 | $360.9M |
| Q1 2024 | 109 | $432.1M |
| Q4 2023 | 87 | $230.8M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $15.7M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 48 | $395.2M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 23,888,888 | $162.7M | 1.46% | +2,188,888+10.1% | Added |
| Ra Capital Management, L.P. | 23,555,648 | $160.4M | 1.39% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 22,713,118 | $154.7M | 0.02% | +343,473+1.5% | Added |
| BlackRock, Inc. | 20,691,927 | $140.9M | 0.00% | +2,326,319+12.7% | Added |
| Vestal Point Capital, LP | 19,415,000 | $132.2M | 3.09% | +1,415,000+7.9% | Added |
| Morgan Stanley | 16,487,479 | $112.3M | 0.01% | −1,477,892−8.2% | Reduced |
| RTW Investments, LP | 13,560,258 | $92.3M | 0.79% | −119,990−0.9% | Reduced |
| FMR LLC | 13,336,413 | $90.8M | 0.00% | −984,842−6.9% | Reduced |
| Vanguard Capital Management LLC | 12,478,595 | $85.0M | 0.00% | +2,247,093+22.0% | Added |
| State Street Corp | 11,421,920 | $77.8M | 0.00% | +212,842+1.9% | Added |
| Siren, L.L.C. | 9,846,579 | $67.1M | 1.36% | +1,016,666+11.5% | Added |
| Octagon Capital Advisors LP | 9,693,244 | $66.0M | 6.06% | +833,333+9.4% | Added |
| Geode Capital Management, LLC | 6,560,394 | $44.7M | 0.00% | +1,028,439+18.6% | Added |
| Polar Capital Holdings Plc | 5,117,133 | $34.8M | 0.10% | −537,207−9.5% | Reduced |
| MPM Oncology Impact Management LP | 4,500,000 | $30.6M | 1.87% | +4,500,000 | New |
| D. E. Shaw & Co., Inc. | 4,398,652 | $30.0M | 0.02% | −28,649−0.6% | Reduced |
| Baker Bros. Advisors LP | 4,004,756 | $27.3M | 0.14% | 00.0% | Unchanged |
| Wellington Management Group LLP | 3,975,605 | $27.1M | 0.00% | +3,349,244+534.7% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 3,885,501 | $26.5M | 0.04% | +1,002,200+34.8% | Added |
| GordonMD Global Investments LP | 723,185 | $24.5M | 11.86% | −14,365−1.9% | Reduced |
| Casdin Capital, LLC | 3,250,000 | $22.1M | 1.11% | 00.0% | Unchanged |
| Vanguard Portfolio Management LLC | 3,140,009 | $21.4M | 0.00% | +1,117,511+55.3% | Added |
| ADAR1 Capital Management, LLC | 3,040,466 | $20.7M | 0.97% | +61,037+2.0% | Added |
| Pictet Asset Management Holding SA | 2,770,701 | $18.9M | 0.02% | +2,751,383+14,242.6% | Added |
| Standard Life Aberdeen plc | 2,327,152 | $15.8M | 0.02% | +1,306,089+127.9% | Added |
| Farallon Capital Management, L.L.C. | 2,250,000 | $15.3M | 0.09% | +2,250,000 | New |
| Norges Bank | 2,233,600 | $15.2M | 0.00% | +2,233,600 | New |
| Northern Trust Corp | 2,226,210 | $15.2M | 0.00% | +411,892+22.7% | Added |
| Charles Schwab Investment Management Inc | 2,200,695 | $15.0M | 0.00% | +392,096+21.7% | Added |
| Millennium Management LLC | 2,126,838 | $14.5M | 0.01% | −1,154,982−35.2% | Reduced |
| OrbiMed Advisors LLC | 2,000,000 | $13.6M | 0.26% | +2,000,000 | New |
| Rice Hall James & Associates, LLC | 1,992,229 | $13.6M | 0.66% | +47,558+2.4% | Added |
| Vanguard Fiduciary Trust Co | 1,896,474 | $12.9M | 0.00% | +366,013+23.9% | Added |
| B Group, Inc. | 1,800,556 | $12.3M | 6.96% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 1,750,000 | $11.9M | 0.58% | +750,000+75.0% | Added |
| Barclays PLC | 1,630,659 | $11.1M | 0.00% | −1,181,351−42.0% | Reduced |
| Citadel Advisors LLC | 1,535,287 | $10.5M | 0.01% | +1,124,152+273.4% | Added |
| Heights Capital Management, Inc | 1,500,000 | $10.2M | 2.36% | +1,500,000 | New |
| Seven Fleet Capital Management LP | 1,504,400 | $9.94M | 1.64% | +878,692+140.4% | Added |
| Palo Alto Investors LP | 1,391,382 | $9.48M | 1.31% | 00.0% | Unchanged |
| Bank of America Corp | 1,372,845 | $9.35M | 0.00% | −304,201−18.1% | Reduced |
| Granahan Investment Management Inc | 1,305,177 | $8.89M | 0.32% | +421,936+47.8% | Added |
| Quantum Private Wealth, LLC | 812,027 | $5.53M | 1.42% | −37,185−4.4% | Reduced |
| First Trust Advisors LP | 791,169 | $5.39M | 0.00% | +791,169 | New |
| JPMorgan Chase & Co | 766,282 | $5.16M | 0.00% | +11,500+1.5% | Added |
| Sands Capital Ventures, LLC | 724,873 | $4.94M | 0.80% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 697,971 | $4.75M | 0.00% | +89,848+14.8% | Added |
| BNP Paribas Arbitrage, SA | 640,035 | $4.36M | 0.00% | +519,835+432.5% | Added |
| Panagora Asset Management Inc | 590,387 | $4.02M | 0.01% | +408,223+224.1% | Added |
| UBS Group AG | 588,427 | $4.01M | 0.00% | +70,729+13.7% | Added |
| Affinity Wealth Management LLC | 576,808 | $3.93M | 0.51% | +576,808 | New |
| Squarepoint Ops LLC | 569,269 | $3.88M | 0.01% | +158,987+38.8% | Added |
| Acuta Capital Partners, LLC | 561,808 | $3.83M | 2.67% | +122,344+27.8% | Added |
| Nuveen, LLC | 555,693 | $3.78M | 0.00% | +6,540+1.2% | Added |
| Adage Capital Partners GP, L.L.C. | 553,000 | $3.77M | 0.01% | +553,000 | New |
| Diadema Partners LP | 522,619 | $3.56M | 1.26% | +522,619 | New |
| Hennion & Walsh Asset Management, Inc. | 519,120 | $3.54M | 0.10% | +127,644+32.6% | Added |
| Woodline Partners LP | 513,828 | $3.50M | 0.01% | 00.0% | Unchanged |
| Holocene Advisors, LP | 510,000 | $3.47M | 0.01% | +510,000 | New |
| Ghisallo Capital Management LLC | 505,000 | $3.44M | 0.07% | +505,000 | New |
| Burkehill Global Management, LP | 500,000 | $3.40M | 0.12% | +500,000 | New |
| Polen Capital Management LLC | 489,219 | $3.33M | 0.03% | +169,471+53.0% | Added |
| Dimensional Fund Advisors LP | 464,771 | $3.16M | 0.00% | −25,701−5.2% | Reduced |
| Voya Investment Management LLC | 425,363 | $2.90M | 0.00% | −86,620−16.9% | Reduced |
| Trexquant Investment LP | 379,577 | $2.58M | 0.02% | +379,577 | New |
| Swiss National Bank | 369,000 | $2.51M | 0.00% | +100,200+37.3% | Added |
| Moore Capital Management, LP | 358,374 | $2.44M | 0.06% | +29,543+9.0% | Added |
| Wells Fargo & Company | 333,314 | $2.27M | 0.00% | +149,980+81.8% | Added |
| Jefferies Financial Group Inc. | 328,800 | $2.24M | 0.02% | −150,200−31.4% | Reduced |
| Citigroup Inc | 306,907 | $2.09M | 0.00% | +249,827+437.7% | Added |
| Rhumbline Advisers | 299,975 | $2.04M | 0.00% | +41,445+16.0% | Added |
| Alps Advisors Inc | 290,543 | $1.98M | 0.01% | +67,557+30.3% | Added |
| UBS Asset Management Americas Inc | 272,600 | $1.86M | 0.00% | +6,805+2.6% | Added |
| Invesco Ltd. | 264,379 | $1.80M | 0.00% | −103,642−28.2% | Reduced |
| Ensign Peak Advisors, Inc | 262,896 | $1.79M | 0.00% | −12,215−4.4% | Reduced |
| Qube Research & Technologies Ltd | 259,605 | $1.77M | 0.00% | +259,605 | New |
| Sphera Funds Management Ltd. | 250,000 | $1.70M | 0.24% | +250,000 | New |
| Deutsche Bank AG | 243,379 | $1.66M | 0.00% | +61,610+33.9% | Added |
| Two Sigma Investments, LP | 234,716 | $1.60M | 0.00% | −507,365−68.4% | Reduced |
| Jane Street Group, LLC | 228,355 | $1.56M | 0.00% | +228,355 | New |
| SG Americas Securities, LLC | 202,260 | $1.38M | 0.00% | −1,974,482−90.7% | Reduced |
| Monashee Investment Management LLC | 200,000 | $1.36M | 2.29% | +200,000 | New |
| Price T Rowe Associates Inc | 199,494 | $1.36M | 0.00% | +40,540+25.5% | Added |
| Privium Fund Management B.V. | 198,900 | $1.35M | 0.25% | +17,000+9.3% | Added |
| Victory Capital Management Inc | 197,578 | $1.35M | 0.00% | +1,833+0.9% | Added |
| Chicago Partners Investment Group LLC | 222,347 | $1.30M | 0.03% | +51,596+30.2% | Added |
| Balyasny Asset Management LLC | 189,332 | $1.29M | 0.00% | +106,313+128.1% | Added |
| State of Wisconsin Investment Board | 177,089 | $1.21M | 0.00% | −86,243−32.8% | Reduced |
| California State Teachers Retirement System | 169,374 | $1.15M | 0.00% | +32,441+23.7% | Added |
| Raymond James Financial Inc | 166,042 | $1.13M | 0.00% | +144,011+653.7% | Added |
| Alliancebernstein L.P. | 247,680 | $1.11M | 0.00% | +58,440+30.9% | Added |
| Wexford Capital LP | 160,654 | $1.09M | 0.15% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 154,706 | $1.05M | 0.00% | −145,197−48.4% | Reduced |
| Palumbo Wealth Management LLC | 149,173 | $1.02M | 0.21% | +2,464+1.7% | Added |
| MetLife Investment Management | 140,846 | $959.2K | 0.00% | +20,730+17.3% | Added |
| Vanguard Global Advisers, LLC | 133,821 | $911.3K | 0.00% | +17,130+14.7% | Added |
| Persistent Asset Partners Ltd | 133,411 | $908.5K | 0.29% | +133,411 | New |
| Vanguard Asset Management, Ltd | 132,614 | $903.1K | 0.00% | +42,140+46.6% | Added |
| AQR Capital Management LLC | 128,764 | $876.9K | 0.00% | −48,545−27.4% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 127,915 | $869.7K | 0.00% | +3,185+2.6% | Added |