Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 191
- +1 vs. Q4 2025
- Shares held
- 265.6M
- +12.1M (+4.8%) vs. Q4 2025
- Total value
- $1.18B
- −$211.2M (−15.1%) vs. Q4 2025
- New holders
- 35
- 69 more added
- Sold out
- 34
- 49 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 23,555,648 | $105.3M | 1.12% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 22,369,645 | $100.0M | 0.01% | +8,676,906+63.4% | Added |
| Avoro Capital Advisors LLC | 21,700,000 | $97.0M | 0.96% | 00.0% | Unchanged |
| BlackRock, Inc. | 18,365,608 | $82.1M | 0.00% | −277,521−1.5% | Reduced |
| Vestal Point Capital, LP | 18,000,000 | $80.5M | 2.25% | +4,250,000+30.9% | Added |
| Morgan Stanley | 17,965,371 | $80.3M | 0.00% | −113,147−0.6% | Reduced |
| FMR LLC | 14,321,255 | $64.0M | 0.00% | +792,889+5.9% | Added |
| RTW Investments, LP | 13,680,248 | $61.2M | 0.61% | −2,718,049−16.6% | Reduced |
| State Street Corp | 11,209,078 | $50.1M | 0.00% | +418,994+3.9% | Added |
| Vanguard Capital Management LLC | 10,231,502 | $45.7M | 0.00% | +10,231,502 | New |
| Octagon Capital Advisors LP | 8,859,911 | $39.6M | 4.38% | 00.0% | Unchanged |
| Siren, L.L.C. | 8,829,913 | $39.5M | 1.09% | −1,300,000−12.8% | Reduced |
| Polar Capital Holdings Plc | 5,654,340 | $25.3M | 0.11% | −2,277,063−28.7% | Reduced |
| Geode Capital Management, LLC | 5,531,955 | $24.7M | 0.00% | +144,929+2.7% | Added |
| D. E. Shaw & Co., Inc. | 4,427,301 | $19.8M | 0.02% | +413,666+10.3% | Added |
| Baker Bros. Advisors LP | 4,004,756 | $17.9M | 0.10% | 00.0% | Unchanged |
| Millennium Management LLC | 3,281,820 | $14.7M | 0.01% | +102,957+3.2% | Added |
| Casdin Capital, LLC | 3,250,000 | $14.5M | 1.10% | +1,750,000+116.7% | Added |
| ADAR1 Capital Management, LLC | 2,979,429 | $13.3M | 0.80% | +483,620+19.4% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 2,883,301 | $12.9M | 0.02% | −838,699−22.5% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 2,722,165 | $12.2M | 0.14% | 00.0% | Unchanged |
| Barclays PLC | 2,812,010 | $11.4M | 0.00% | −2,726,991−49.2% | Reduced |
| SG Americas Securities, LLC | 2,176,742 | $9.73M | 0.01% | +1,395,268+178.5% | Added |
| Vanguard Portfolio Management LLC | 2,022,498 | $9.04M | 0.00% | +2,022,498 | New |
| Rice Hall James & Associates, LLC | 1,944,671 | $8.69M | 0.48% | +674,026+53.0% | Added |
| Northern Trust Corp | 1,814,318 | $8.11M | 0.00% | +576,331+46.6% | Added |
| Charles Schwab Investment Management Inc | 1,808,599 | $8.08M | 0.00% | −94,379−5.0% | Reduced |
| B Group, Inc. | 1,800,556 | $8.05M | 5.97% | 00.0% | Unchanged |
| Bank of America Corp | 1,677,046 | $7.50M | 0.00% | +524,366+45.5% | Added |
| Vanguard Fiduciary Trust Co | 1,530,461 | $6.84M | 0.00% | +1,530,461 | New |
| Palo Alto Investors LP | 1,391,382 | $6.22M | 0.95% | +208,187+17.6% | Added |
| Standard Life Aberdeen plc | 1,021,063 | $4.56M | 0.01% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 1,000,000 | $4.47M | 0.26% | −2,300,000−69.7% | Reduced |
| Granahan Investment Management Inc | 883,241 | $3.95M | 0.19% | +179,270+25.5% | Added |
| Quantum Private Wealth, LLC | 849,212 | $3.80M | 1.17% | +29,497+3.6% | Added |
| Two Sigma Investments, LP | 742,081 | $3.32M | 0.00% | +390,955+111.3% | Added |
| Sands Capital Ventures, LLC | 724,873 | $3.24M | 0.77% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 754,782 | $3.07M | 0.00% | −19,630−2.5% | Reduced |
| Wellington Management Group LLP | 626,361 | $2.80M | 0.00% | −84,874−11.9% | Reduced |
| Seven Fleet Capital Management LP | 625,708 | $2.80M | 0.88% | +458,485+274.2% | Added |
| Bank of New York Mellon Corp | 608,123 | $2.72M | 0.00% | −16,244−2.6% | Reduced |
| Nuveen, LLC | 549,153 | $2.45M | 0.00% | +3,867+0.7% | Added |
| UBS Group AG | 517,698 | $2.31M | 0.00% | +134,655+35.2% | Added |
| Woodline Partners LP | 513,828 | $2.30M | 0.01% | +13,828+2.8% | Added |
| Voya Investment Management LLC | 511,983 | $2.29M | 0.00% | +293,798+134.7% | Added |
| Dimensional Fund Advisors LP | 490,472 | $2.18M | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 479,000 | $2.14M | 0.03% | +454,000+1,816.0% | Added |
| Point72 Asset Management, L.P. | 461,856 | $2.06M | 0.00% | −3,406,826−88.1% | Reduced |
| Acuta Capital Partners, LLC | 439,464 | $1.96M | 1.40% | −15,363−3.4% | Reduced |
| Renaissance Technologies LLC | 413,203 | $1.85M | 0.00% | +242,103+141.5% | Added |
| Citadel Advisors LLC | 411,135 | $1.84M | 0.00% | −1,443,720−77.8% | Reduced |
| Squarepoint Ops LLC | 410,282 | $1.83M | 0.00% | −61,295−13.0% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 391,476 | $1.75M | 0.06% | +83,019+26.9% | Added |
| Invesco Ltd. | 368,021 | $1.65M | 0.00% | −964,759−72.4% | Reduced |
| Moore Capital Management, LP | 328,831 | $1.47M | 0.05% | +328,831 | New |
| Polen Capital Management LLC | 319,748 | $1.43M | 0.01% | +163,162+104.2% | Added |
| Rafferty Asset Management, LLC | 299,903 | $1.34M | 0.01% | −44,881−13.0% | Reduced |
| Ensign Peak Advisors, Inc | 275,111 | $1.23M | 0.00% | 00.0% | Unchanged |
| Swiss National Bank | 268,800 | $1.20M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 265,795 | $1.19M | 0.00% | +98,295+58.7% | Added |
| State of Wisconsin Investment Board | 263,332 | $1.18M | 0.00% | +150,154+132.7% | Added |
| Rhumbline Advisers | 258,530 | $1.16M | 0.00% | +1,090+0.4% | Added |
| Superstring Capital Management LP | 258,269 | $1.15M | 0.82% | −722,499−73.7% | Reduced |
| Chicago Partners Investment Group LLC | 170,751 | $1.15M | 0.03% | +4,210+2.5% | Added |
| Alliancebernstein L.P. | 189,240 | $1.04M | 0.00% | +9,600+5.3% | Added |
| Alps Advisors Inc | 222,986 | $996.7K | 0.00% | −1,934−0.9% | Reduced |
| Victory Capital Management Inc | 195,745 | $875.0K | 0.00% | −190.0% | Reduced |
| Wells Fargo & Company | 183,334 | $819.5K | 0.00% | −121,752−39.9% | Reduced |
| Panagora Asset Management Inc | 182,164 | $814.3K | 0.00% | +170,590+1,473.9% | Added |
| Privium Fund Management B.V. | 181,900 | $813.1K | 0.17% | +17,000+10.3% | Added |
| Deutsche Bank AG | 181,769 | $812.5K | 0.00% | +20,990+13.1% | Added |
| AQR Capital Management LLC | 177,309 | $792.6K | 0.00% | +8,447+5.0% | Added |
| Wexford Capital LP | 160,654 | $718.1K | 0.12% | −20,199−11.2% | Reduced |
| Price T Rowe Associates Inc | 158,954 | $711.0K | 0.00% | +37,140+30.5% | Added |
| Palumbo Wealth Management LLC | 146,709 | $655.8K | 0.16% | −31,298−17.6% | Reduced |
| Tudor Investment Corp Et Al | 143,575 | $641.8K | 0.00% | +143,575 | New |
| California State Teachers Retirement System | 136,933 | $612.1K | 0.00% | −1,647−1.2% | Reduced |
| Profund Advisors LLC | 134,671 | $602.0K | 0.02% | +6,081+4.7% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 124,730 | $549.0K | 0.00% | +2,091+1.7% | Added |
| BNP Paribas Arbitrage, SA | 120,200 | $537.3K | 0.00% | −52,282−30.3% | Reduced |
| MetLife Investment Management | 120,116 | $536.9K | 0.00% | +6,850+6.0% | Added |
| Vanguard Global Advisers, LLC | 116,691 | $521.6K | 0.00% | +116,691 | New |
| Susquehanna International Group, LLP | 116,297 | $519.8K | 0.00% | −8,678−6.9% | Reduced |
| Franklin Resources Inc | 108,399 | $484.5K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 104,308 | $466.3K | 0.00% | −28,838−21.7% | Reduced |
| Manufacturers Life Insurance Company, The | 99,371 | $444.2K | 0.00% | +32,286+48.1% | Added |
| Vanguard Asset Management, Ltd | 90,474 | $404.4K | 0.00% | +90,474 | New |
| Balyasny Asset Management LLC | 83,019 | $371.1K | 0.00% | +40,949+97.3% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 80,779 | $361.1K | 0.00% | +13,302+19.7% | Added |
| Janus Henderson Group PLC | 69,000 | $308.1K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 67,500 | $301.7K | 0.00% | 00.0% | Unchanged |
| Red Reef Advisors LLC | 65,950 | $294.8K | 0.31% | 00.0% | Unchanged |
| Creative Planning | 59,801 | $267.3K | 0.00% | −3,434−5.4% | Reduced |
| VARCOV Co. | 58,511 | $261.5K | 0.10% | +58,511 | New |
| Commonwealth Equity Services, LLC | 58,442 | $261.2K | 0.00% | +2,785+5.0% | Added |
| Abacus Wealth Partners, LLC | 58,241 | $260.3K | 0.02% | +3,068+5.6% | Added |
| Police & Firemen's Retirement System of New Jersey | 57,168 | $255.5K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 57,080 | $255.1K | 0.00% | −5,935−9.4% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 56,577 | $252.9K | 0.00% | −1,398−2.4% | Reduced |
| NBC Securities, Inc. | 54,058 | $241.6K | 0.02% | +1,103+2.1% | Added |