Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 109
- +22 vs. Q4 2023
- Shares held
- 140.2M
- +10.0M (+7.7%) vs. Q4 2023
- Total value
- $402.2M
- +$171.9M (+74.6%) vs. Q4 2023
- New holders
- 36
- 29 more added
- Sold out
- 14
- 27 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 20,110,717 | $57.7M | 0.00% | −2,328,407−10.4% | Reduced |
| Avoro Capital Advisors LLC | 18,650,000 | $53.5M | 0.62% | +14,294,445+328.2% | Added |
| RTW Investments, LP | 18,593,185 | $53.4M | 0.79% | +1,700,000+10.1% | Added |
| Ra Capital Management, L.P. | 10,872,503 | $31.2M | 0.40% | −7,600,000−41.1% | Reduced |
| VR Adviser, LLC | 9,000,000 | $25.8M | 1.23% | −1,412,872−13.6% | Reduced |
| Vanguard Group Inc | 5,917,414 | $17.0M | 0.00% | −278,153−4.5% | Reduced |
| Morgan Stanley | 5,168,890 | $14.8M | 0.00% | +4,952,352+2,287.1% | Added |
| Baker Bros. Advisors LP | 4,004,756 | $11.5M | 0.14% | 00.0% | Unchanged |
| Tybourne Capital Management (HK) Ltd | 3,700,000 | $10.6M | 1.82% | 00.0% | Unchanged |
| Artal Group S.A. | 3,687,548 | $10.6M | 0.27% | +24,444+0.7% | Added |
| Acuta Capital Partners, LLC | 3,333,333 | $9.57M | 6.21% | −256,000−7.1% | Reduced |
| Millennium Management LLC | 3,135,317 | $9.00M | 0.01% | −245,215−7.3% | Reduced |
| Octagon Capital Advisors LP | 3,030,000 | $8.70M | 1.06% | +3,030,000 | New |
| BlackRock Inc. | 2,597,303 | $7.45M | 0.00% | −101,935−3.8% | Reduced |
| Polar Capital Holdings Plc | 2,518,909 | $7.23M | 0.04% | 00.0% | Unchanged |
| Eversept Partners, LP | 2,325,591 | $6.67M | 0.50% | −1,455,123−38.5% | Reduced |
| Eagle Asset Management Inc | 1,789,394 | $5.08M | 0.03% | +1,789,394 | New |
| Cowen and Company, LLC | 1,550,000 | $4.45M | 0.17% | +1,550,000 | New |
| Susquehanna International Group, LLP | 1,309,627 | $3.76M | 0.01% | −118,519−8.3% | Reduced |
| Point72 Asset Management, L.P. | 1,113,232 | $3.19M | 0.01% | −1,574,768−58.6% | Reduced |
| Price T Rowe Associates Inc | 1,099,329 | $3.16M | 0.00% | −128,004−10.4% | Reduced |
| StemPoint Capital LP | 1,087,785 | $3.12M | 0.83% | +1,087,785 | New |
| Qube Research & Technologies Ltd | 1,072,070 | $3.08M | 0.01% | +953,549+804.5% | Added |
| Goldman Sachs Group Inc | 1,058,962 | $3.04M | 0.00% | +975,488+1,168.6% | Added |
| Marshall Wace, LLP | 1,030,657 | $2.96M | 0.00% | +1,030,657 | New |
| Geode Capital Management, LLC | 1,019,791 | $2.93M | 0.00% | +34,370+3.5% | Added |
| Ghost Tree Capital, LLC | 950,000 | $2.73M | 0.88% | −1,150,000−54.8% | Reduced |
| Soleus Capital Management, L.P. | 925,000 | $2.65M | 0.23% | +925,000 | New |
| Palo Alto Investors LP | 811,268 | $2.33M | 0.26% | +281,407+53.1% | Added |
| Sands Capital Ventures, LLC | 724,873 | $2.08M | 0.50% | 00.0% | Unchanged |
| Quantum Private Wealth, LLC | 698,520 | $2.00M | 0.74% | +59,000+9.2% | Added |
| Alphabet Inc. | 640,882 | $1.84M | 0.07% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 552,595 | $1.59M | 0.01% | −566,780−50.6% | Reduced |
| HRT Financial LP | 414,980 | $1.19M | 0.01% | +414,980 | New |
| State Street Corp | 339,520 | $974.4K | 0.00% | +196,300+137.1% | Added |
| Renaissance Technologies LLC | 328,500 | $943.0K | 0.00% | −768,900−70.1% | Reduced |
| Kovitz Investment Group Partners, LLC | 277,778 | $797.2K | 0.01% | 00.0% | Unchanged |
| Citigroup Inc | 255,203 | $732.4K | 0.00% | −55,760−17.9% | Reduced |
| Marathon Trading Investment Management LLC | 223,900 | $642.6K | 0.25% | +223,900 | New |
| Adage Capital Partners GP, L.L.C. | 220,000 | $631.4K | 0.00% | −200,000−47.6% | Reduced |
| Squarepoint Ops LLC | 213,946 | $614.0K | 0.00% | +150,469+237.0% | Added |
| Northern Trust Corp | 211,395 | $606.7K | 0.00% | −2,326−1.1% | Reduced |
| UBS Group AG | 189,284 | $543.2K | 0.00% | +185,341+4,700.5% | Added |
| Balyasny Asset Management LLC | 188,698 | $541.6K | 0.00% | +188,698 | New |
| Point72 Asia (Singapore) Pte. Ltd. | 181,306 | $520.3K | 0.14% | +181,306 | New |
| TD Asset Management Inc | 175,600 | $504.0K | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 172,769 | $495.8K | 0.05% | +172,769 | New |
| Laurion Capital Management LP | 164,258 | $471.4K | 0.01% | +164,258 | New |
| Cubist Systematic Strategies, LLC | 161,100 | $462.4K | 0.01% | +112,666+232.6% | Added |
| Diametric Capital, LP | 153,478 | $440.5K | 0.24% | +84,607+122.8% | Added |
| Bank of America Corp | 125,713 | $360.8K | 0.00% | +3,385+2.8% | Added |
| EntryPoint Capital, LLC | 122,905 | $352.7K | 0.32% | −168,711−57.9% | Reduced |
| Two Sigma Investments, LP | 121,517 | $348.8K | 0.00% | −15,456−11.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 112,413 | $322.6K | 0.00% | +77,013+217.6% | Added |
| ExodusPoint Capital Management, LP | 112,077 | $322.0K | 0.00% | +112,077 | New |
| Engineers Gate Manager LP | 110,992 | $318.5K | 0.01% | +89,296+411.6% | Added |
| Chicago Partners Investment Group LLC | 125,284 | $317.0K | 0.01% | −9,567−7.1% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 97,054 | $278.5K | 0.02% | +97,054 | New |
| JPMorgan Chase & Co | 93,741 | $269.0K | 0.00% | +57,257+156.9% | Added |
| Old Mission Capital LLC | 76,419 | $219.3K | 0.01% | +76,419 | New |
| Manufacturers Life Insurance Company, The | 63,726 | $182.9K | 0.00% | +2,179+3.5% | Added |
| GTS Securities LLC | 61,352 | $176.1K | 0.00% | +61,352 | New |
| Jane Street Group, LLC | 58,886 | $169.0K | 0.00% | +16,608+39.3% | Added |
| Prelude Capital Management, LLC | 55,893 | $160.4K | 0.01% | −133,983−70.6% | Reduced |
| Jump Financial, LLC | 54,090 | $155.2K | 0.00% | +54,090 | New |
| Charles Schwab Investment Management Inc | 51,462 | $147.7K | 0.00% | +35,322+218.8% | Added |
| Jefferies Financial Group Inc. | 48,100 | $138.0K | 0.00% | +48,100 | New |
| Dynamic Advisor Solutions LLC | 45,000 | $129.2K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 43,500 | $124.8K | 0.03% | −165,500−79.2% | Reduced |
| LPL Financial LLC | 42,062 | $120.7K | 0.00% | −15,998−27.6% | Reduced |
| XTX Topco Ltd | 41,052 | $117.8K | 0.02% | +24,767+152.1% | Added |
| China Universal Asset Management Co., Ltd. | 35,908 | $103.1K | 0.01% | +14,286+66.1% | Added |
| LMR Partners LLP | 32,485 | $93.2K | 0.00% | +32,485 | New |
| CTC Alternative Strategies, Ltd. | 29,800 | $85.5K | 0.05% | +29,800 | New |
| Leonteq Securities AG | 28,000 | $80.4K | 0.01% | +20,000+250.0% | Added |
| Omers Administration Corp | 28,000 | $80.4K | 0.00% | +28,000 | New |
| Williams & Novak, LLC | 45,000 | $79.7K | 0.09% | 00.0% | Unchanged |
| Polymer Capital Management (HK) LTD | 27,680 | $79.4K | 0.02% | +27,680 | New |
| Commonwealth Equity Services, LLC | 27,269 | $78.0K | 0.00% | +500+1.9% | Added |
| Acadian Asset Management LLC | 26,477 | $75.0K | 0.00% | −433,589−94.2% | Reduced |
| Cannon Global Investment Management, LLC | 24,200 | $69.5K | 0.19% | +24,200 | New |
| Tower Research Capital LLC (TRC) | 24,129 | $69.3K | 0.00% | +21,258+740.4% | Added |
| Lee Financial Co | 20,000 | $57.4K | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 19,050 | $54.7K | 0.00% | 00.0% | Unchanged |
| DRW Securities, LLC | 17,800 | $51.1K | 0.00% | +17,800 | New |
| US Bancorp | 17,638 | $50.6K | 0.00% | +17,638 | New |
| Cambridge Investment Research Advisors, Inc. | 17,290 | $50.0K | 0.00% | +17,290 | New |
| Victory Capital Management Inc | 16,918 | $48.6K | 0.00% | +1,318+8.4% | Added |
| StoneX Group Inc. | 14,382 | $41.3K | 0.00% | +14,382 | New |
| Howard Capital Management Inc. | 14,165 | $40.7K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 13,103 | $37.6K | 0.00% | +1,157+9.7% | Added |
| Walleye Capital LLC | 13,000 | $37.3K | 0.00% | +13,000 | New |
| TradeLink Capital LLC | 11,300 | $32.0K | 0.48% | +11,300 | New |
| Twinbeech Capital LP | 10,204 | $29.3K | 0.00% | +10,204 | New |
| Symmetry Investments LP | 10,100 | $29.0K | 0.00% | +10,100 | New |
| Capital Investment Advisors, LLC | 10,000 | $28.7K | 0.00% | 00.0% | Unchanged |
| Quarry LP | 10,000 | $28.7K | 0.01% | +2,000+25.0% | Added |
| Wells Fargo & Company | 7,408 | $21.3K | 0.00% | −21−0.3% | Reduced |
| Lazard Asset Management LLC | 5,804 | $16.0K | 0.00% | −3,001−34.1% | Reduced |
| Headlands Technologies LLC | 2,315 | $6.64K | 0.00% | +2,315 | New |