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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
109
+22 vs. Q4 2023
Shares held
140.2M
+10.0M (+7.7%) vs. Q4 2023
Total value
$402.2M
+$171.9M (+74.6%) vs. Q4 2023
New holders
36
29 more added
Sold out
14
27 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 109 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ1 2024: $402.2M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2023.

Institutions holding TSHA in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
Macquarie Group Ltd8,066$230.00%+8,066New
Advisor Group Holdings, Inc.134$3870.00%00.0%Unchanged
Citadel Advisors LLC197$5660.00%−2,297,359−100.0%Reduced
Riggs Asset Managment Co. Inc.198$5690.00%+198New
Morton Brown Family Wealth, LLC260$7460.00%00.0%Unchanged
Aquatic Capital Management LLC400$1.15K0.00%+400New
Daiwa Securities Group Inc.691$2.00K0.00%+691New
Allworth Financial LP1,000$2.87K0.00%00.0%Unchanged
Headlands Technologies LLC2,315$6.64K0.00%+2,315New
Lazard Asset Management LLC5,804$16.0K0.00%−3,001−34.1%Reduced
Wells Fargo & Company7,408$21.3K0.00%−21−0.3%Reduced
Capital Investment Advisors, LLC10,000$28.7K0.00%00.0%Unchanged
Quarry LP10,000$28.7K0.01%+2,000+25.0%Added
Symmetry Investments LP10,100$29.0K0.00%+10,100New
Twinbeech Capital LP10,204$29.3K0.00%+10,204New
TradeLink Capital LLC11,300$32.0K0.48%+11,300New
Walleye Capital LLC13,000$37.3K0.00%+13,000New
ProShare Advisors LLC13,103$37.6K0.00%+1,157+9.7%Added
Howard Capital Management Inc.14,165$40.7K0.00%00.0%Unchanged
StoneX Group Inc.14,382$41.3K0.00%+14,382New
Victory Capital Management Inc16,918$48.6K0.00%+1,318+8.4%Added
Cambridge Investment Research Advisors, Inc.17,290$50.0K0.00%+17,290New
US Bancorp17,638$50.6K0.00%+17,638New
DRW Securities, LLC17,800$51.1K0.00%+17,800New
Prudential Financial Inc19,050$54.7K0.00%00.0%Unchanged
Lee Financial Co20,000$57.4K0.01%00.0%Unchanged
Tower Research Capital LLC (TRC)24,129$69.3K0.00%+21,258+740.4%Added
Cannon Global Investment Management, LLC24,200$69.5K0.19%+24,200New
Acadian Asset Management LLC26,477$75.0K0.00%−433,589−94.2%Reduced
Commonwealth Equity Services, LLC27,269$78.0K0.00%+500+1.9%Added
Polymer Capital Management (HK) LTD27,680$79.4K0.02%+27,680New
Williams & Novak, LLC45,000$79.7K0.09%00.0%Unchanged
Leonteq Securities AG28,000$80.4K0.01%+20,000+250.0%Added
Omers Administration Corp28,000$80.4K0.00%+28,000New
CTC Alternative Strategies, Ltd.29,800$85.5K0.05%+29,800New
LMR Partners LLP32,485$93.2K0.00%+32,485New
China Universal Asset Management Co., Ltd.35,908$103.1K0.01%+14,286+66.1%Added
XTX Topco Ltd41,052$117.8K0.02%+24,767+152.1%Added
LPL Financial LLC42,062$120.7K0.00%−15,998−27.6%Reduced
ADAR1 Capital Management, LLC43,500$124.8K0.03%−165,500−79.2%Reduced
Dynamic Advisor Solutions LLC45,000$129.2K0.00%00.0%Unchanged
Jefferies Financial Group Inc.48,100$138.0K0.00%+48,100New
Charles Schwab Investment Management Inc51,462$147.7K0.00%+35,322+218.8%Added
Jump Financial, LLC54,090$155.2K0.00%+54,090New
Prelude Capital Management, LLC55,893$160.4K0.01%−133,983−70.6%Reduced
Jane Street Group, LLC58,886$169.0K0.00%+16,608+39.3%Added
GTS Securities LLC61,352$176.1K0.00%+61,352New
Manufacturers Life Insurance Company, The63,726$182.9K0.00%+2,179+3.5%Added
Old Mission Capital LLC76,419$219.3K0.01%+76,419New
JPMorgan Chase & Co93,741$269.0K0.00%+57,257+156.9%Added
Y-Intercept (Hong Kong) Ltd97,054$278.5K0.02%+97,054New
Chicago Partners Investment Group LLC125,284$317.0K0.01%−9,567−7.1%Reduced
Engineers Gate Manager LP110,992$318.5K0.01%+89,296+411.6%Added
ExodusPoint Capital Management, LP112,077$322.0K0.00%+112,077New
Connor, Clark & Lunn Investment Management Ltd.112,413$322.6K0.00%+77,013+217.6%Added
Two Sigma Investments, LP121,517$348.8K0.00%−15,456−11.3%Reduced
EntryPoint Capital, LLC122,905$352.7K0.32%−168,711−57.9%Reduced
Bank of America Corp125,713$360.8K0.00%+3,385+2.8%Added
Diametric Capital, LP153,478$440.5K0.24%+84,607+122.8%Added
Cubist Systematic Strategies, LLC161,100$462.4K0.01%+112,666+232.6%Added
Laurion Capital Management LP164,258$471.4K0.01%+164,258New
Brevan Howard Capital Management LP172,769$495.8K0.05%+172,769New
TD Asset Management Inc175,600$504.0K0.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.181,306$520.3K0.14%+181,306New
Balyasny Asset Management LLC188,698$541.6K0.00%+188,698New
UBS Group AG189,284$543.2K0.00%+185,341+4,700.5%Added
Northern Trust Corp211,395$606.7K0.00%−2,326−1.1%Reduced
Squarepoint Ops LLC213,946$614.0K0.00%+150,469+237.0%Added
Adage Capital Partners GP, L.L.C.220,000$631.4K0.00%−200,000−47.6%Reduced
Marathon Trading Investment Management LLC223,900$642.6K0.25%+223,900New
Citigroup Inc255,203$732.4K0.00%−55,760−17.9%Reduced
Kovitz Investment Group Partners, LLC277,778$797.2K0.01%00.0%Unchanged
Renaissance Technologies LLC328,500$943.0K0.00%−768,900−70.1%Reduced
State Street Corp339,520$974.4K0.00%+196,300+137.1%Added
HRT Financial LP414,980$1.19M0.01%+414,980New
Schonfeld Strategic Advisors LLC552,595$1.59M0.01%−566,780−50.6%Reduced
Alphabet Inc.640,882$1.84M0.07%00.0%Unchanged
Quantum Private Wealth, LLC698,520$2.00M0.74%+59,000+9.2%Added
Sands Capital Ventures, LLC724,873$2.08M0.50%00.0%Unchanged
Palo Alto Investors LP811,268$2.33M0.26%+281,407+53.1%Added
Soleus Capital Management, L.P.925,000$2.65M0.23%+925,000New
Ghost Tree Capital, LLC950,000$2.73M0.88%−1,150,000−54.8%Reduced
Geode Capital Management, LLC1,019,791$2.93M0.00%+34,370+3.5%Added
Marshall Wace, LLP1,030,657$2.96M0.00%+1,030,657New
Goldman Sachs Group Inc1,058,962$3.04M0.00%+975,488+1,168.6%Added
Qube Research & Technologies Ltd1,072,070$3.08M0.01%+953,549+804.5%Added
StemPoint Capital LP1,087,785$3.12M0.83%+1,087,785New
Price T Rowe Associates Inc1,099,329$3.16M0.00%−128,004−10.4%Reduced
Point72 Asset Management, L.P.1,113,232$3.19M0.01%−1,574,768−58.6%Reduced
Susquehanna International Group, LLP1,309,627$3.76M0.01%−118,519−8.3%Reduced
Cowen and Company, LLC1,550,000$4.45M0.17%+1,550,000New
Eagle Asset Management Inc1,789,394$5.08M0.03%+1,789,394New
Eversept Partners, LP2,325,591$6.67M0.50%−1,455,123−38.5%Reduced
Polar Capital Holdings Plc2,518,909$7.23M0.04%00.0%Unchanged
BlackRock Inc.2,597,303$7.45M0.00%−101,935−3.8%Reduced
Octagon Capital Advisors LP3,030,000$8.70M1.06%+3,030,000New
Millennium Management LLC3,135,317$9.00M0.01%−245,215−7.3%Reduced
Acuta Capital Partners, LLC3,333,333$9.57M6.21%−256,000−7.1%Reduced
Artal Group S.A.3,687,548$10.6M0.27%+24,444+0.7%Added