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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
59
−10 vs. Q1 2022
Shares held
14.7M
−2.29M (−13.5%) vs. Q1 2022
Total value
$54.7M
−$56.1M (−50.6%) vs. Q1 2022
New holders
14
15 more added
Sold out
24
24 more reduced

2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 59 institutions
Q1 2021: 46 institutionsQ2 2021: 48 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ2 2022: $54.7M
Q1 2021: $358.5MQ2 2021: $388.4MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202148$388.4M
Q1 202146$358.5M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2022.

Institutions holding TSHA in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC3,295,689$12.3M0.00%+8680.0%Added
Nantahala Capital Management, LLC1,643,438$6.11M0.53%+309,491+23.2%Added
Vanguard Group Inc1,070,802$3.98M0.00%+58,638+5.8%Added
BlackRock Inc.1,046,490$3.89M0.00%−1,147,213−52.3%Reduced
Artal Group S.A.1,040,882$3.87M0.22%00.0%Unchanged
Franklin Resources Inc811,069$3.02M0.00%−489,599−37.6%Reduced
Sands Capital Ventures, LLC724,873$2.70M0.74%00.0%Unchanged
Alphabet Inc.640,882$2.38M0.13%00.0%Unchanged
Renaissance Technologies LLC523,600$1.95M0.00%+273,100+109.0%Added
Tybourne Capital Management (HK) Ltd500,000$1.86M0.13%00.0%Unchanged
Laurion Capital Management LP442,600$1.65M0.07%+442,600New
JPMorgan Chase & Co279,291$1.04M0.00%−160,513−36.5%Reduced
Geode Capital Management, LLC238,239$886.0K0.00%−171,331−41.8%Reduced
Millennium Management LLC216,168$804.0K0.00%+216,168New
Gsa Capital Partners LLP186,480$694.0K0.10%+69,371+59.2%Added
Carlson Capital L P165,000$614.0K0.04%+165,000New
Quantum Private Wealth, LLC157,774$586.0K0.35%+5,800+3.8%Added
D. E. Shaw & Co., Inc.134,585$501.0K0.00%+59,851+80.1%Added
Citadel Advisors LLC110,591$411.0K0.00%−98,158−47.0%Reduced
State of Wisconsin Investment Board110,500$411.0K0.00%+7,400+7.2%Added
Two Sigma Advisers, LP105,800$394.0K0.00%−30,500−22.4%Reduced
UBS Group AG94,560$352.0K0.00%+26,580+39.1%Added
Marshall Wace, LLP91,670$341.0K0.00%−47,716−34.2%Reduced
Ergoteles LLC91,800$341.0K0.01%+91,800New
Charles Schwab Investment Management Inc90,711$338.0K0.00%−74,634−45.1%Reduced
State Street Corp77,420$288.0K0.00%−421,794−84.5%Reduced
Morgan Stanley71,651$265.0K0.00%−104,104−59.2%Reduced
Bridgeway Capital Management, LLC70,809$263.0K0.01%+70,809New
Goldman Sachs Group Inc69,279$258.0K0.00%−19,760−22.2%Reduced
Two Sigma Investments, LP67,644$252.0K0.00%−114,264−62.8%Reduced
Bank of America Corp66,043$246.0K0.00%−5,315−7.4%Reduced
Thompson Siegel & Walmsley LLC56,100$209.0K0.00%+14,000+33.3%Added
Acadian Asset Management LLC53,447$199.0K0.00%+53,447New
Barclays PLC47,879$184.0K0.00%+3,492+7.9%Added
Cornercap Investment Counsel Inc39,756$148.0K0.03%+39,756New
Northern Trust Corp38,821$144.0K0.00%−166,804−81.1%Reduced
Occudo Quantitative Strategies LP31,030$115.0K0.01%+4,702+17.9%Added
Davenport & Co LLC27,170$101.0K0.00%−500−1.8%Reduced
Schonfeld Strategic Advisors LLC24,100$90.0K0.00%+4,100+20.5%Added
Susquehanna International Group, LLP21,163$79.0K0.00%+21,163New
Trexquant Investment LP19,548$73.0K0.00%−51,935−72.7%Reduced
Sargent Investment Group, LLC17,788$66.0K0.02%+7,132+66.9%Added
Qube Research & Technologies Ltd17,836$66.0K0.00%+17,836New
HSBC Holdings PLC16,570$63.0K0.00%+16,570New
RBF Capital, LLC13,800$51.0K0.00%+13,800New
Bank of New York Mellon Corp11,670$44.0K0.00%−66,567−85.1%Reduced
AQR Capital Management LLC10,134$38.0K0.00%+10,134New
683 Capital Management, LLC10,000$37.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,259$12.0K0.00%+1,659+103.7%Added
Citigroup Inc1,158$4.00K0.00%−9,158−88.8%Reduced
Royal Bank of Canada1,019$4.00K0.00%−1,392−57.7%Reduced
Allworth Financial LP1,000$4.00K0.00%+1,000New
Quantbot Technologies LP829$3.00K0.00%−2,100−71.7%Reduced
Captrust Financial Advisors821$3.00K0.00%−200−19.6%Reduced
New York State Common Retirement Fund191$1.00K0.00%−14,100−98.7%Reduced
Wells Fargo & Company163$1.00K0.00%−1,282−88.7%Reduced
Truvestments Capital LLC380$1.00K0.00%+380New
Credit Suisse AG12$00.00%−15,189−99.9%Reduced
Daiwa Securities Group Inc.112$00.00%00.0%Unchanged
TimesSquare Capital Management, LLC0$00.00%−665,900−100.0%Sold out
Nuveen Asset Management, LLC0$00.00%−105,426−100.0%Sold out
1623 Capital LLC0$00.00%−46,763−100.0%Sold out
Swiss National Bank0$00.00%−41,000−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−33,694−100.0%Sold out
California State Teachers Retirement System0$00.00%−24,435−100.0%Sold out
Rhumbline Advisers0$00.00%−22,389−100.0%Sold out
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.0$00.00%−21,834−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−19,800−100.0%Sold out
Caption Management, LLC0$00.00%−18,191−100.0%Sold out
Legal & General Group Plc0$00.00%−16,100−100.0%Sold out
Jump Financial, LLC0$00.00%−13,700−100.0%Sold out
Deutsche Bank AG0$00.00%−12,366−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−11,233−100.0%Sold out
American International Group, Inc.0$00.00%−11,244−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−10,878−100.0%Sold out
Amalgamated Bank0$00.00%−3,535−100.0%Sold out
Ameritas Investment Partners, Inc.0$00.00%−1,745−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−1,410−100.0%Sold out
Macquarie Group Ltd0$00.00%−867−100.0%Sold out
Simplex Trading, LLC0$00.00%−320−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−241−100.0%Sold out
Signaturefd, LLC0$00.00%−165−100.0%Sold out
Tarbox Family Office, Inc.0$00.00%−175−100.0%Sold out
Parametric Portfolio Associates LLC––––Not filed
Amalgamated Financial Corp.––––Not filed