Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- −3 vs. Q4 2024
- Shares held
- 166.9M
- −74.2K (0.0%) vs. Q4 2024
- Total value
- $232.0M
- −$56.8M (−19.7%) vs. Q4 2024
- New holders
- 22
- 38 more added
- Sold out
- 25
- 31 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 19,999,999 | $27.8M | 0.43% | 00.0% | Unchanged |
| RTW Investments, LP | 18,787,866 | $26.1M | 0.40% | +10,115,236+116.6% | Added |
| Morgan Stanley | 16,846,374 | $23.4M | 0.00% | −793,992−4.5% | Reduced |
| FMR LLC | 15,631,954 | $21.7M | 0.00% | −733,710−4.5% | Reduced |
| BlackRock, Inc. | 13,589,178 | $18.9M | 0.00% | +57,711+0.4% | Added |
| Ra Capital Management, L.P. | 10,872,503 | $15.1M | 0.25% | 00.0% | Unchanged |
| Octagon Capital Advisors LP | 10,700,000 | $14.9M | 3.23% | +250,000+2.4% | Added |
| Vanguard Group Inc | 8,770,921 | $12.2M | 0.00% | −135,843−1.5% | Reduced |
| Siren, L.L.C. | 6,514,737 | $9.06M | 0.51% | −87,738−1.3% | Reduced |
| Point72 Asset Management, L.P. | 4,569,678 | $6.35M | 0.02% | +4,569,678 | New |
| Baker Bros. Advisors LP | 4,004,756 | $5.57M | 0.06% | 00.0% | Unchanged |
| Tybourne Capital Management (HK) Ltd | 3,700,000 | $5.14M | 21.83% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 3,664,732 | $5.10M | 0.00% | +92,383+2.6% | Added |
| State Street Corp | 3,233,512 | $4.49M | 0.00% | −3,240,855−50.1% | Reduced |
| Polar Capital Holdings Plc | 3,000,000 | $4.17M | 0.03% | 00.0% | Unchanged |
| Millennium Management LLC | 1,772,654 | $2.46M | 0.00% | +1,621,040+1,069.2% | Added |
| Granahan Investment Management Inc | 1,640,793 | $2.28M | 0.11% | +4,412+0.3% | Added |
| Northern Trust Corp | 1,431,666 | $1.99M | 0.00% | −27,066−1.9% | Reduced |
| Palo Alto Investors LP | 1,419,468 | $1.97M | 0.38% | +608,200+75.0% | Added |
| B Group, Inc. | 1,255,556 | $1.75M | 1.52% | +290,000+30.0% | Added |
| ADAR1 Capital Management, LLC | 1,066,309 | $1.48M | 0.29% | +888,602+500.0% | Added |
| JPMorgan Chase & Co | 1,003,067 | $1.39M | 0.00% | −1,640,688−62.1% | Reduced |
| Woodline Partners LP | 858,254 | $1.19M | 0.01% | −169,268−16.5% | Reduced |
| Quantum Private Wealth, LLC | 791,476 | $1.10M | 0.42% | −3,500−0.4% | Reduced |
| Superstring Capital Management LP | 755,599 | $1.05M | 1.25% | +755,599 | New |
| Sands Capital Ventures, LLC | 724,873 | $1.01M | 0.25% | 00.0% | Unchanged |
| Barclays PLC | 708,966 | $985.5K | 0.00% | +373,728+111.5% | Added |
| Alphabet Inc. | 640,882 | $890.8K | 0.06% | 00.0% | Unchanged |
| Bank of America Corp | 636,842 | $885.2K | 0.00% | −1,073,461−62.8% | Reduced |
| Wellington Management Group LLP | 625,198 | $869.0K | 0.00% | +39,604+6.8% | Added |
| Charles Schwab Investment Management Inc | 547,128 | $760.5K | 0.00% | +72,871+15.4% | Added |
| Nuveen, LLC | 546,414 | $759.5K | 0.00% | +546,414 | New |
| DAFNA Capital Management LLC | 522,500 | $726.3K | 0.21% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 453,420 | $630.3K | 0.00% | +3,159+0.7% | Added |
| UBS Group AG | 418,132 | $581.2K | 0.00% | −3,264−0.8% | Reduced |
| Goldman Sachs Group Inc | 359,007 | $499.0K | 0.00% | −608,137−62.9% | Reduced |
| Kovitz Investment Group Partners, LLC | 292,778 | $407.0K | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 245,254 | $340.9K | 0.01% | +245,254 | New |
| Susquehanna International Group, LLP | 227,472 | $316.2K | 0.00% | +85,009+59.7% | Added |
| Citadel Advisors LLC | 216,611 | $301.1K | 0.00% | −528,594−70.9% | Reduced |
| Rhumbline Advisers | 205,462 | $285.6K | 0.00% | +13,383+7.0% | Added |
| XTX Topco Ltd | 203,129 | $282.3K | 0.01% | +203,129 | New |
| Invesco Ltd. | 159,899 | $222.3K | 0.00% | +72,544+83.0% | Added |
| Chicago Partners Investment Group LLC | 116,565 | $221.5K | 0.01% | +521+0.4% | Added |
| Los Angeles Capital Management LLC | 142,810 | $198.5K | 0.00% | +5,350+3.9% | Added |
| HRT Financial LP | 139,692 | $194.0K | 0.00% | +139,692 | New |
| EntryPoint Capital, LLC | 135,897 | $188.9K | 0.09% | +74,402+121.0% | Added |
| Privium Fund Management B.V. | 134,900 | $187.5K | 0.05% | 00.0% | Unchanged |
| Deutsche Bank AG | 134,418 | $186.8K | 0.00% | −16,665−11.0% | Reduced |
| Citigroup Inc | 133,194 | $185.1K | 0.00% | −120,098−47.4% | Reduced |
| BIT Capital GmbH | 117,062 | $162.7K | 0.02% | +117,062 | New |
| Franklin Resources Inc | 116,238 | $161.6K | 0.00% | +116,238 | New |
| Wells Fargo & Company | 109,048 | $151.6K | 0.00% | +5,664+5.5% | Added |
| Alliancebernstein L.P. | 108,250 | $150.5K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 107,899 | $150.0K | 0.00% | +82,545+325.6% | Added |
| MetLife Investment Management | 107,711 | $149.7K | 0.00% | +44,721+71.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 103,074 | $143.3K | 0.00% | −5,530−5.1% | Reduced |
| Intech Investment Management LLC | 99,912 | $138.9K | 0.00% | +31,877+46.9% | Added |
| Corebridge Financial, Inc. | 85,878 | $119.4K | 0.00% | −1,272−1.5% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 83,864 | $116.6K | 0.01% | +83,864 | New |
| Leonteq Securities AG | 79,999 | $111.2K | 0.01% | 00.0% | Unchanged |
| Creative Planning | 78,335 | $108.9K | 0.00% | +57,547+276.8% | Added |
| Price T Rowe Associates Inc | 74,025 | $103.0K | 0.00% | +8,694+13.3% | Added |
| Virtus Investment Advisers, Inc. | 72,957 | $101.4K | 0.03% | +72,957 | New |
| Manufacturers Life Insurance Company, The | 63,797 | $88.7K | 0.00% | +786+1.2% | Added |
| Commonwealth Equity Services, LLC | 60,069 | $83.0K | 0.00% | +1,000+1.7% | Added |
| Mariner, LLC | 58,490 | $81.3K | 0.00% | +148+0.3% | Added |
| Voya Investment Management LLC | 48,616 | $67.6K | 0.00% | −2,600−5.1% | Reduced |
| ProShare Advisors LLC | 47,195 | $65.6K | 0.00% | −11,881−20.1% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 45,678 | $63.5K | 0.00% | 00.0% | Unchanged |
| Jain Global LLC | 45,200 | $62.8K | 0.00% | +45,200 | New |
| China Universal Asset Management Co., Ltd. | 41,120 | $57.2K | 0.01% | −2,336−5.4% | Reduced |
| Williams & Novak, LLC | 45,000 | $56.9K | 0.06% | 00.0% | Unchanged |
| CIBC World Markets Corp | 38,897 | $54.1K | 0.00% | +22,492+137.1% | Added |
| First Manhattan Co | 28,500 | $39.6K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 23,490 | $33.0K | 0.00% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 22,844 | $31.8K | 0.00% | −149−0.6% | Reduced |
| State Board of Administration of Florida Retirement System | 22,700 | $31.6K | 0.00% | +2,690+13.4% | Added |
| New York State Common Retirement Fund | 21,100 | $29.3K | 0.00% | 00.0% | Unchanged |
| Lee Financial Co | 20,000 | $27.8K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 19,958 | $27.7K | 0.00% | −60−0.3% | Reduced |
| HSBC Holdings PLC | 20,257 | $27.7K | 0.00% | −134−0.7% | Reduced |
| Victory Capital Management Inc | 19,017 | $26.4K | 0.00% | +16+0.1% | Added |
| Ameritas Investment Partners, Inc. | 15,672 | $21.8K | 0.00% | 00.0% | Unchanged |
| Point72 (DIFC) Ltd | 15,528 | $21.6K | 0.00% | +15,528 | New |
| Prudential Financial Inc | 15,140 | $21.0K | 0.00% | +2,150+16.6% | Added |
| Howard Capital Management Inc. | 14,165 | $19.7K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 13,989 | $19.4K | 0.00% | −982−6.6% | Reduced |
| Two Sigma Securities, LLC | 13,071 | $18.2K | 0.00% | +13,071 | New |
| Xponance, Inc. | 12,639 | $17.6K | 0.00% | +714+6.0% | Added |
| California State Teachers Retirement System | 12,635 | $17.6K | 0.00% | 00.0% | Unchanged |
| Marex Group plc | 12,500 | $17.4K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 12,241 | $17.0K | 0.00% | −11,403−48.2% | Reduced |
| SIH Partners, LLLP | 12,173 | $16.9K | 0.00% | +12,173 | New |
| Catalyst Funds Management Pty Ltd | 11,900 | $16.5K | 0.00% | +11,900 | New |
| Camelot Portfolios, LLC | 11,000 | $15.3K | 0.01% | +11,000 | New |
| CWM, LLC | 10,527 | $15.0K | 0.00% | +10,262+3,872.5% | Added |
| Bordeaux Wealth Advisors LLC | 10,109 | $14.1K | 0.00% | +10,109 | New |
| Mackenzie Financial Corp | 10,000 | $13.9K | 0.00% | 00.0% | Unchanged |
| Capital Investment Advisors, LLC | 10,000 | $13.9K | 0.00% | 00.0% | Unchanged |