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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
107
−2 vs. Q1 2024
Shares held
158.2M
+18.0M (+12.8%) vs. Q1 2024
Total value
$354.3M
−$47.9M (−11.9%) vs. Q1 2024
New holders
36
29 more added
Sold out
38
21 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 107 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ2 2024: $354.3M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2024.

Institutions holding TSHA in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC21,210,636$47.5M0.00%+1,099,919+5.5%Added
RTW Investments, LP18,800,299$42.1M0.65%+207,114+1.1%Added
Avoro Capital Advisors LLC18,650,000$41.8M0.56%00.0%Unchanged
BlackRock Inc.11,742,449$26.3M0.00%+9,145,146+352.1%Added
Ra Capital Management, L.P.10,872,503$24.4M0.32%00.0%Unchanged
VR Adviser, LLC9,000,000$20.2M1.28%00.0%Unchanged
Morgan Stanley7,477,397$16.7M0.00%+2,308,507+44.7%Added
Vanguard Group Inc7,167,337$16.1M0.00%+1,249,923+21.1%Added
Octagon Capital Advisors LP4,572,222$10.2M1.69%+1,542,222+50.9%Added
Artal Group S.A.4,354,214$9.75M0.25%+666,666+18.1%Added
Baker Bros. Advisors LP4,004,756$8.97M0.11%00.0%Unchanged
Tybourne Capital Management (HK) Ltd3,700,000$8.29M1.69%00.0%Unchanged
State Street Corp3,318,421$7.43M0.00%+2,978,901+877.4%Added
Polar Capital Holdings Plc3,025,000$6.78M0.04%+506,091+20.1%Added
JPMorgan Chase & Co2,963,553$6.64M0.00%+2,869,812+3,061.4%Added
Geode Capital Management, LLC2,880,485$6.45M0.00%+1,860,694+182.5%Added
Deutsche Bank AG2,537,348$5.68M0.00%+2,537,348New
Acuta Capital Partners, LLC2,330,937$5.22M4.40%−1,002,396−30.1%Reduced
Eagle Asset Management Inc1,722,586$3.89M0.02%−66,808−3.7%Reduced
Price T Rowe Associates Inc1,276,578$2.86M0.00%+177,249+16.1%Added
Ghost Tree Capital, LLC1,250,000$2.80M0.97%+300,000+31.6%Added
Nuveen Asset Management, LLC1,079,099$2.42M0.00%+1,079,099New
Goldman Sachs Group Inc1,027,018$2.30M0.00%−31,944−3.0%Reduced
Woodline Partners LP1,026,269$2.30M0.02%+1,026,269New
Palo Alto Investors LP811,268$1.82M0.21%00.0%Unchanged
Granahan Investment Management Inc809,691$1.81M0.07%+809,691New
Marshall Wace, LLP786,094$1.76M0.00%−244,563−23.7%Reduced
Schonfeld Strategic Advisors LLC769,200$1.72M0.01%+216,605+39.2%Added
Quantum Private Wealth, LLC730,520$1.64M0.58%+32,000+4.6%Added
Sands Capital Ventures, LLC724,873$1.62M0.54%00.0%Unchanged
Alphabet Inc.640,882$1.44M0.07%00.0%Unchanged
Qube Research & Technologies Ltd632,500$1.42M0.00%−439,570−41.0%Reduced
Diametric Capital, LP512,361$1.15M0.62%+358,883+233.8%Added
Bank of New York Mellon Corp454,464$1.02M0.00%+454,464New
Charles Schwab Investment Management Inc429,744$962.6K0.00%+378,282+735.1%Added
Invesco Ltd.397,750$891.0K0.00%+397,750New
Millennium Management LLC340,724$763.2K0.00%−2,794,593−89.1%Reduced
Kovitz Investment Group Partners, LLC292,778$655.8K0.01%+15,000+5.4%Added
Northern Trust Corp270,766$606.5K0.00%+59,371+28.1%Added
Jefferies Financial Group Inc.257,694$577.2K0.01%+209,594+435.7%Added
ADAR1 Capital Management, LLC250,800$561.8K0.11%+207,300+476.6%Added
Prelude Capital Management, LLC186,591$418.0K0.04%+130,698+233.8%Added
Rhumbline Advisers184,284$412.8K0.00%+184,284New
TD Asset Management Inc175,600$393.3K0.00%00.0%Unchanged
Alpine Global Management, LLC151,483$339.3K0.06%+151,483New
Gsa Capital Partners LLP141,805$318.0K0.02%+141,805New
Manufacturers Life Insurance Company, The133,213$298.4K0.00%+69,487+109.0%Added
Susquehanna International Group, LLP129,200$289.4K0.00%−1,180,427−90.1%Reduced
Jane Street Group, LLC128,124$287.0K0.00%+69,238+117.6%Added
Bank of America Corp123,974$277.7K0.00%−1,739−1.4%Reduced
Chicago Partners Investment Group LLC116,905$263.0K0.01%−8,379−6.7%Reduced
Alliancebernstein L.P.95,600$214.1K0.00%+95,600New
Privium Fund Management B.V.98,500$212.8K0.05%+98,500New
Corebridge Financial, Inc.86,058$193.6K0.00%+86,058New
Squarepoint Ops LLC80,255$179.8K0.00%−133,691−62.5%Reduced
Wells Fargo & Company69,742$156.2K0.00%+62,334+841.4%Added
New York State Common Retirement Fund64,800$145.2K0.00%+64,800New
Virtu Financial LLC57,191$128.0K0.01%+57,191New
UBS Group AG56,079$125.6K0.00%−133,205−70.4%Reduced
Voya Investment Management LLC53,934$120.8K0.00%+53,934New
Leonteq Securities AG53,000$118.7K0.02%+25,000+89.3%Added
Barclays PLC54,234$117.4K0.00%+54,234New
LPL Financial LLC48,060$107.7K0.00%+5,998+14.3%Added
Citadel Advisors LLC46,854$105.0K0.00%+46,657+23,683.8%Added
Redwood Wealth Management Group, LLC46,400$103.9K0.08%+46,400New
Marathon Trading Investment Management LLC45,340$101.6K0.03%−178,560−79.7%Reduced
Dynamic Advisor Solutions LLC45,000$100.8K0.00%00.0%Unchanged
Williams & Novak, LLC45,000$100.8K0.09%00.0%Unchanged
Citigroup Inc43,935$98.4K0.00%−211,268−82.8%Reduced
Scientech Research LLC43,350$97.1K0.02%+43,350New
MetLife Investment Management41,794$93.6K0.00%+41,794New
Renaissance Technologies LLC41,100$92.1K0.00%−287,400−87.5%Reduced
Commonwealth Equity Services, LLC27,269$61.0K0.00%00.0%Unchanged
Tudor Investment Corp Et Al26,634$59.7K0.00%+26,634New
China Universal Asset Management Co., Ltd.21,971$49.2K0.01%−13,937−38.8%Reduced
Virtus ETF Advisers LLC21,709$48.6K0.02%+21,709New
Principal Financial Group Inc21,609$48.4K0.00%+21,609New
Lee Financial Co20,000$44.8K0.01%00.0%Unchanged
Victory Capital Management Inc18,062$40.5K0.00%+1,144+6.8%Added
Legal & General Group Plc17,925$40.2K0.00%+17,925New
Cambridge Investment Research Advisors, Inc.16,505$37.0K0.00%−785−4.5%Reduced
US Bancorp16,077$36.0K0.00%−1,561−8.9%Reduced
Ameritas Investment Partners, Inc.15,672$35.1K0.00%+15,672New
Royal Bank of Canada15,696$35.0K0.00%+15,696New
Howard Capital Management Inc.14,165$31.7K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)13,037$29.2K0.00%−11,092−46.0%Reduced
Marex Group plc12,500$28.0K0.00%+12,500New
California State Teachers Retirement System11,591$26.0K0.00%+11,591New
ProShare Advisors LLC11,545$25.9K0.00%−1,558−11.9%Reduced
Prudential Financial Inc11,190$25.1K0.00%−7,860−41.3%Reduced
Camelot Portfolios, LLC11,000$24.6K0.01%+11,000New
Schechter Investment Advisors, LLC10,613$23.8K0.00%+10,613New
Capital Investment Advisors, LLC10,000$22.4K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.5,583$12.1K0.00%+5,583New
Amalgamated Bank5,534$12.0K0.00%+5,534New
International Assets Investment Management, LLC2,000$4.48K0.00%+2,000New
State of Wyoming1,797$4.03K0.00%+1,797New
The PNC Financial Services Group, Inc.1,000$2.24K0.00%+1,000New
Allworth Financial LP1,000$2.14K0.00%00.0%Unchanged
Daiwa Securities Group Inc.691$2.00K0.00%00.0%Unchanged