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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Taysha Gene Therapies, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
119
+13 vs. Q2 2024
Shares held
157.0M
+10.6M (+7.2%) vs. Q2 2024
Total value
$315.5M
−$12.4M (−3.8%) vs. Q2 2024
New holders
31
45 more added
Sold out
18
16 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 119 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ3 2024: $315.5M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q2 2024.

Institutions holding TSHA in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC18,678,527$37.5M0.00%−2,532,109−11.9%Reduced
Avoro Capital Advisors LLC18,650,000$37.5M0.55%00.0%Unchanged
RTW Investments, LP14,946,420$30.0M0.43%−3,853,879−20.5%Reduced
BlackRock, Inc.13,520,533$27.2M0.00%+13,520,533New
Ra Capital Management, L.P.10,872,503$21.9M0.25%00.0%Unchanged
VR Adviser, LLC9,000,000$18.1M0.95%00.0%Unchanged
Vanguard Group Inc8,265,459$16.6M0.00%+1,098,122+15.3%Added
Morgan Stanley7,663,993$15.4M0.00%+186,596+2.5%Added
Siren, L.L.C.4,879,875$9.81M0.49%+4,879,875New
Octagon Capital Advisors LP4,572,222$9.19M1.47%00.0%Unchanged
Baker Bros. Advisors LP4,004,756$8.05M0.08%00.0%Unchanged
Tybourne Capital Management (HK) Ltd3,700,000$7.44M2.08%00.0%Unchanged
Geode Capital Management, LLC3,562,758$7.16M0.00%+682,273+23.7%Added
State Street Corp3,469,068$6.97M0.00%+150,647+4.5%Added
Polar Capital Holdings Plc3,025,000$6.08M0.04%00.0%Unchanged
JPMorgan Chase & Co3,001,397$6.03M0.00%+37,844+1.3%Added
Citadel Advisors LLC2,859,972$5.75M0.01%+2,813,118+6,004.0%Added
Deutsche Bank AG2,560,284$5.15M0.00%+22,936+0.9%Added
Ghost Tree Capital, LLC2,150,000$4.32M1.47%+900,000+72.0%Added
Acuta Capital Partners, LLC2,118,992$4.26M3.45%−211,945−9.1%Reduced
Northern Trust Corp1,372,525$2.76M0.00%+1,101,759+406.9%Added
Goldman Sachs Group Inc1,205,671$2.42M0.00%+178,653+17.4%Added
Granahan Investment Management Inc1,139,899$2.29M0.09%+330,208+40.8%Added
Woodline Partners LP1,027,494$2.07M0.02%+1,225+0.1%Added
Schonfeld Strategic Advisors LLC843,200$1.69M0.01%+74,000+9.6%Added
Palo Alto Investors LP811,268$1.63M0.21%00.0%Unchanged
Quantum Private Wealth, LLC767,616$1.54M0.52%+37,096+5.1%Added
Sands Capital Ventures, LLC724,873$1.46M0.41%00.0%Unchanged
Alphabet Inc.640,882$1.29M0.07%00.0%Unchanged
Nuveen Asset Management, LLC566,850$1.14M0.00%−512,249−47.5%Reduced
Marshall Wace, LLP486,026$976.9K0.00%−300,068−38.2%Reduced
Wellington Management Group LLP463,192$931.0K0.00%+463,192New
Charles Schwab Investment Management Inc462,867$930.4K0.00%+33,123+7.7%Added
Qube Research & Technologies Ltd352,684$708.9K0.00%−279,816−44.2%Reduced
Bank of New York Mellon Corp338,272$679.9K0.00%−116,192−25.6%Reduced
Kovitz Investment Group Partners, LLC292,778$588.5K0.00%00.0%Unchanged
Barclays PLC247,280$511.9K0.00%+193,046+356.0%Added
ADAR1 Capital Management, LLC251,400$505.3K0.08%+600+0.2%Added
Gsa Capital Partners LLP233,560$469.0K0.04%+91,755+64.7%Added
Los Angeles Capital Management LLC206,992$416.1K0.00%+206,992New
Rhumbline Advisers186,248$374.3K0.00%+1,964+1.1%Added
Susquehanna International Group, LLP176,492$354.7K0.00%+47,292+36.6%Added
Bank of America Corp133,735$268.8K0.00%+9,761+7.9%Added
Citigroup Inc132,612$266.6K0.00%+88,677+201.8%Added
Privium Fund Management B.V.120,000$241.2K0.06%+21,500+21.8%Added
Chicago Partners Investment Group LLC118,175$232.8K0.01%+1,270+1.1%Added
Alliancebernstein L.P.108,250$217.6K0.00%+12,650+13.2%Added
Jane Street Group, LLC107,572$216.2K0.00%−20,552−16.0%Reduced
Squarepoint Ops LLC103,123$207.3K0.00%+22,868+28.5%Added
Franklin Resources Inc100,795$200.6K0.00%+100,795New
Corebridge Financial, Inc.92,098$185.1K0.00%+6,040+7.0%Added
UBS Group AG92,001$184.9K0.00%+35,922+64.1%Added
Mirae Asset Global ETFs Holdings Ltd.88,053$177.0K0.00%+88,053New
Invesco Ltd.85,681$172.2K0.00%−312,069−78.5%Reduced
Leonteq Securities AG80,000$160.8K0.02%+27,000+50.9%Added
MetLife Investment Management76,037$152.8K0.00%+34,243+81.9%Added
Jefferies Financial Group Inc.73,857$148.5K0.00%−183,837−71.3%Reduced
Wells Fargo & Company71,927$144.6K0.00%+2,185+3.1%Added
AQR Capital Management LLC69,471$139.6K0.00%+69,471New
ExodusPoint Capital Management, LP68,264$137.0K0.00%+68,264New
SG Americas Securities, LLC63,984$129.0K0.00%+63,984New
Manufacturers Life Insurance Company, The60,665$121.9K0.00%−72,548−54.5%Reduced
Price T Rowe Associates Inc59,719$121.0K0.00%−1,216,859−95.3%Reduced
Voya Investment Management LLC55,044$110.6K0.00%+1,110+2.1%Added
Williams & Novak, LLC45,000$90.5K0.08%00.0%Unchanged
ProShare Advisors LLC44,658$89.8K0.00%+33,113+286.8%Added
Intech Investment Management LLC42,094$84.6K0.00%+42,094New
China Universal Asset Management Co., Ltd.39,417$79.2K0.01%+17,446+79.4%Added
SEI Investments Co39,188$78.8K0.00%+39,188New
Simplex Trading, LLC38,813$78.0K0.00%+38,813New
Royal Bank of Canada36,340$72.0K0.00%+20,644+131.5%Added
Commonwealth Equity Services, LLC28,069$56.0K0.00%+800+2.9%Added
EntryPoint Capital, LLC27,027$54.3K0.03%+27,027New
Cambridge Investment Research Advisors, Inc.23,505$47.0K0.00%+7,000+42.4%Added
Virtus ETF Advisers LLC22,103$44.4K0.02%+394+1.8%Added
Nebula Research & Development LLC21,737$43.7K0.01%+21,737New
New York State Common Retirement Fund21,100$42.4K0.00%−43,700−67.4%Reduced
Legal & General Group Plc20,018$40.2K0.00%+2,093+11.7%Added
State Board of Administration of Florida Retirement System20,010$40.2K0.00%+20,010New
Victory Capital Management Inc20,007$40.2K0.00%+1,945+10.8%Added
Lee Financial Co20,000$40.2K0.01%00.0%Unchanged
Principal Financial Group Inc15,799$31.8K0.00%−5,810−26.9%Reduced
Ameritas Investment Partners, Inc.15,672$31.5K0.00%00.0%Unchanged
Howard Capital Management Inc.14,165$28.5K0.00%00.0%Unchanged
Creative Planning14,118$28.4K0.00%+14,118New
Tower Research Capital LLC (TRC)13,852$27.8K0.00%+815+6.3%Added
Mariner, LLC13,336$26.8K0.00%+13,336New
California State Teachers Retirement System12,635$25.4K0.00%+1,044+9.0%Added
Marex Group plc12,500$25.1K0.00%00.0%Unchanged
HSBC Holdings PLC12,315$24.8K0.00%+12,315New
Prudential Financial Inc11,190$22.5K0.00%00.0%Unchanged
Aigen Investment Management, LP11,189$22.5K0.00%+11,189New
Xponance, Inc.10,869$21.8K0.00%+10,869New
Capital Investment Advisors, LLC10,000$20.1K0.00%00.0%Unchanged
Mackenzie Financial Corp10,000$20.1K0.00%+10,000New
Mirae Asset Global Investments Co., Ltd.7,412$15.3K0.00%+1,829+32.8%Added
Atticus Wealth Management, LLC7,425$14.9K0.00%+7,425New
CIBC Private Wealth Group, LLC6,833$13.7K0.00%+6,833New
Amalgamated Bank5,534$11.0K0.00%00.0%Unchanged
Oliver Lagore Vanvalin Investment Group2,800$5.63K0.00%+2,800New