Skip to main content

Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Taysha Gene Therapies, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
63
+24 vs. Q2 2023
Shares held
130.0M
+116.3M (+848.4%) vs. Q2 2023
Total value
$410.6M
+$401.6M (+4,435.1%) vs. Q2 2023
New holders
35
14 more added
Sold out
11
6 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 63 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ3 2023: $410.6M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q2 2023.

Institutions holding TSHA in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC24,527,801$77.5M0.01%+23,378,974+2,035.0%Added
Ra Capital Management, L.P.18,472,503$58.4M1.15%+18,472,503New
RTW Investments, LP16,893,185$53.4M1.13%+16,893,185New
VR Adviser, LLC14,444,444$45.6M4.80%+14,444,444New
TCG Crossover Management, LLC11,111,111$35.1M5.17%+11,111,111New
Vanguard Group Inc5,327,864$16.8M0.00%+3,738,616+235.2%Added
Avoro Capital Advisors LLC3,925,000$12.4M0.19%+3,925,000New
Acuta Capital Partners, LLC3,827,926$12.1M8.80%+3,827,926New
Artal Group S.A.3,663,104$11.6M0.50%+2,222,222+154.2%Added
Kynam Capital Management, LP3,281,313$10.4M1.72%+3,281,313New
Octagon Capital Advisors LP2,777,778$8.78M1.55%+2,777,778New
Polar Capital Holdings Plc2,530,000$7.99M0.06%+2,530,000New
Baker Bros. Advisors LP2,504,756$7.92M0.05%+2,504,756New
Eversept Partners, LP1,705,774$5.39M0.60%+1,705,774New
Tybourne Capital Management (HK) Ltd1,500,000$4.74M0.66%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,500,000$4.74M0.01%+1,500,000New
Ghost Tree Capital, LLC1,325,000$4.19M2.03%+1,325,000New
Price T Rowe Associates Inc1,247,471$3.94M0.00%+1,247,471New
Point72 Asset Management, L.P.936,550$2.96M0.01%+936,550New
Franklin Resources Inc810,840$2.56M0.00%00.0%Unchanged
Diametric Capital, LP760,014$2.40M1.00%+760,014New
BlackRock Inc.748,068$2.36M0.00%+427,043+133.0%Added
Sands Capital Ventures, LLC724,873$2.29M0.68%00.0%Unchanged
Schonfeld Strategic Advisors LLC720,043$2.28M0.02%+720,043New
Alphabet Inc.640,882$2.03M0.13%00.0%Unchanged
Renaissance Technologies LLC598,000$1.89M0.00%+373,600+166.5%Added
Quantum Private Wealth, LLC575,380$1.82M0.87%+71,000+14.1%Added
Geode Capital Management, LLC461,666$1.46M0.00%+103,813+29.0%Added
EAM Investors, LLC335,390$1.06M0.20%+335,390New
Citigroup Inc281,119$888.3K0.00%+281,119New
Prelude Capital Management, LLC240,251$759.2K0.07%+240,251New
Susquehanna International Group, LLP202,617$640.3K0.00%+202,617New
TD Asset Management Inc175,600$554.9K0.00%+175,600New
Morgan Stanley172,069$543.7K0.00%+40,761+31.0%Added
Bridgeway Capital Management, LLC156,300$493.9K0.01%00.0%Unchanged
State Street Corp140,020$442.5K0.00%+25,100+21.8%Added
Verition Fund Management LLC85,034$268.7K0.00%+85,034New
Chicago Partners Investment Group LLC111,111$242.2K0.01%+111,111New
Northern Trust Corp66,190$209.2K0.00%−6,768−9.3%Reduced
Manufacturers Life Insurance Company, The61,547$194.5K0.00%+61,547New
LPL Financial LLC56,935$179.9K0.00%+56,935New
Dynamic Advisor Solutions LLC45,000$142.2K0.01%00.0%Unchanged
Redwood Wealth Management Group, LLC38,200$120.7K0.14%+150+0.4%Added
Bank of America Corp38,180$120.6K0.00%+8,749+29.7%Added
Squarepoint Ops LLC28,568$90.3K0.00%−52,066−64.6%Reduced
Two Sigma Securities, LLC27,637$87.3K0.00%+27,637New
Commonwealth Equity Services, LLC26,971$85.0K0.00%+8,246+44.0%Added
Bank of New York Mellon Corp26,074$82.4K0.00%+26,074New
Kovitz Investment Group Partners, LLC25,000$79.0K0.00%+10,000+66.7%Added
Lee Financial Co20,000$63.2K0.01%+20,000New
Prudential Financial Inc17,250$54.5K0.00%+17,250New
Charles Schwab Investment Management Inc16,140$51.0K0.00%00.0%Unchanged
Simplex Trading, LLC14,639$46.0K0.00%+8,758+148.9%Added
Capital Investment Advisors, LLC10,000$31.6K0.00%+10,000New
Wells Fargo & Company6,540$20.7K0.00%−12,653−65.9%Reduced
Group One Trading, L.P.5,622$17.8K0.00%+5,622New
Leonteq Securities AG5,000$15.8K0.00%+5,000New
Allworth Financial LP1,000$3.16K0.00%00.0%Unchanged
UBS Group AG550$1.74K0.00%−7,359−93.0%Reduced
JPMorgan Chase & Co137$4330.00%−1,645−92.3%Reduced
Advisor Group Holdings, Inc.134$4260.00%+134New
Royal Bank of Canada19$00.00%−131−87.3%Reduced
Capital Advisors, Ltd. LLC79$00.00%+79New
Nantahala Capital Management, LLC0$00.00%−1,251,139−100.0%Sold out
Laurion Capital Management LP0$00.00%−1,171,832−100.0%Sold out
Millennium Management LLC0$00.00%−614,938−100.0%Sold out
Carlson Capital L P0$00.00%−484,000−100.0%Sold out
Acadian Asset Management LLC0$00.00%−70,798−100.0%Sold out
Sargent Investment Group, LLC0$00.00%−25,634−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−18,077−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−14,435−100.0%Sold out
Engineers Gate Manager LP0$00.00%−13,650−100.0%Sold out
Citadel Advisors LLC0$00.00%−11,293−100.0%Sold out
Camelot Portfolios, LLC0$00.00%−11,000−100.0%Sold out