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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
52
−2 vs. Q3 2022
Shares held
19.4M
+5.44M (+39.1%) vs. Q3 2022
Total value
$43.8M
+$16.8M (+62.0%) vs. Q3 2022
New holders
14
21 more added
Sold out
16
9 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 52 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ4 2022: $43.8M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2022.

Institutions holding TSHA in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC3,204,922$7.24M0.00%−80,861−2.5%Reduced
Nantahala Capital Management, LLC2,999,765$6.78M0.61%+1,388,943+86.2%Added
Vanguard Group Inc1,555,666$3.52M0.00%+484,864+45.3%Added
Tybourne Capital Management (HK) Ltd1,500,000$3.39M0.34%+1,000,000+200.0%Added
Artal Group S.A.1,440,882$3.26M0.19%+400,000+38.4%Added
Laurion Capital Management LP1,292,600$2.92M0.08%+850,000+192.0%Added
Franklin Resources Inc811,069$1.83M0.00%00.0%Unchanged
Sands Capital Ventures, LLC724,873$1.64M0.45%00.0%Unchanged
BlackRock Inc.714,057$1.61M0.00%−321,592−31.1%Reduced
Alphabet Inc.640,882$1.45M0.08%00.0%Unchanged
Carlson Capital L P560,000$1.27M0.10%+360,000+180.0%Added
Renaissance Technologies LLC519,800$1.18M0.00%+101,300+24.2%Added
Millennium Management LLC386,589$874.0K0.00%+212,211+121.7%Added
Altium Capital Management LP359,051$811.5K0.42%+359,051New
Geode Capital Management, LLC331,741$749.0K0.00%+91,326+38.0%Added
Quantum Private Wealth, LLC313,457$708.4K0.45%+84,388+36.8%Added
Acadian Asset Management LLC261,851$590.0K0.00%+208,404+389.9%Added
Bank of Montreal202,199$459.0K0.00%+202,199New
UBS Group AG201,834$456.1K0.00%+195,562+3,118.0%Added
Gsa Capital Partners LLP183,857$416.0K0.05%−52,263−22.1%Reduced
Citadel Advisors LLC183,711$415.2K0.00%+133,131+263.2%Added
Susquehanna International Group, LLP160,724$363.2K0.00%+160,724New
State Street Corp114,920$259.7K0.00%+37,500+48.4%Added
Bridgeway Capital Management, LLC104,869$237.0K0.01%−35,000−25.0%Reduced
Northern Trust Corp72,958$164.9K0.00%+33,031+82.7%Added
Marshall Wace, LLP69,296$156.6K0.00%+69,296New
Cornercap Investment Counsel Inc55,359$125.1K0.02%+1,006+1.9%Added
Bank of America Corp50,376$113.8K0.00%−19,129−27.5%Reduced
Sargent Investment Group, LLC42,987$97.2K0.03%+17,745+70.3%Added
Barclays PLC44,013$96.8K0.00%−3,866−8.1%Reduced
Cubist Systematic Strategies, LLC40,301$91.1K0.00%+40,301New
Redwood Wealth Management Group, LLC35,600$80.5K0.10%+35,600New
Morgan Stanley23,607$53.4K0.00%−1,355−5.4%Reduced
Caas Capital Management LP22,994$52.0K0.01%+22,994New
Jump Financial, LLC16,917$38.2K0.00%+16,917New
Charles Schwab Investment Management Inc16,140$36.5K0.00%00.0%Unchanged
Kovitz Investment Group Partners, LLC15,000$34.0K0.00%+15,000New
Maven Securities LTD15,000$33.9K0.01%+15,000New
RBF Capital, LLC13,800$31.0K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC13,725$31.0K0.00%+13,725New
Goldman Sachs Group Inc12,127$27.4K0.00%−31,356−72.1%Reduced
Tower Research Capital LLC (TRC)11,018$25.0K0.00%+1,655+17.7%Added
Bordeaux Wealth Advisors LLC10,000$22.6K0.01%00.0%Unchanged
Northwestern Mutual Wealth Management Co10,000$22.6K0.00%+10,000New
Quantbot Technologies LP9,729$22.0K0.00%+8,900+1,073.6%Added
JPMorgan Chase & Co1,782$4.00K0.00%−42,776−96.0%Reduced
Wells Fargo & Company1,268$2.87K0.00%+318+33.5%Added
Allworth Financial LP1,000$2.26K0.00%00.0%Unchanged
Group One Trading, L.P.444$1.00K0.00%+444New
Truvestments Capital LLC380$8590.00%00.0%Unchanged
Money Concepts Capital Corp115$2600.00%+115New
Royal Bank of Canada24$00.00%+5+26.3%Added
D. E. Shaw & Co., Inc.0$00.00%−107,274−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−87,700−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−86,600−100.0%Sold out
Ergoteles LLC0$00.00%−76,743−100.0%Sold out
Thompson Siegel & Walmsley LLC0$00.00%−56,100−100.0%Sold out
Two Sigma Investments, LP0$00.00%−43,378−100.0%Sold out
HSBC Holdings PLC0$00.00%−16,570−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−16,000−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−14,679−100.0%Sold out
Bank of New York Mellon Corp0$00.00%−11,295−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−11,000−100.0%Sold out
683 Capital Management, LLC0$00.00%−10,000−100.0%Sold out
Citigroup Inc0$00.00%−635−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−385−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−112−100.0%Sold out
Simplex Trading, LLC0$00.00%−347−100.0%Sold out