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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
127
−3 vs. Q4 2024
Shares held
166.9M
−74.2K (0.0%) vs. Q4 2024
Total value
$232.0M
−$56.8M (−19.7%) vs. Q4 2024
New holders
22
38 more added
Sold out
25
31 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 127 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ1 2025: $232.0M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2024.

Institutions holding TSHA in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
Quadrant Capital Group LLC2$30.00%+2New
SBI Securities Co., Ltd.80$1110.00%00.0%Unchanged
True Wealth Design, LLC132$1840.00%+132New
Advisor Group Holdings, Inc.134$1870.00%00.0%Unchanged
Sterling Capital Management LLC165$2290.00%00.0%Unchanged
Coldstream Capital Management Inc207$2880.00%+207New
Morton Brown Family Wealth, LLC260$3610.00%00.0%Unchanged
Parallel Advisors, LLC280$3890.00%00.0%Unchanged
CoreCap Advisors, LLC290$4030.00%−90−23.7%Reduced
EverSource Wealth Advisors, LLC372$5170.00%+372New
Lindbrook Capital, LLC435$6050.00%−335−43.5%Reduced
Signaturefd, LLC553$7690.00%+271+96.1%Added
Daiwa Securities Group Inc.691$1.00K0.00%00.0%Unchanged
Optiver Holding B.V.805$1.12K0.00%−548−40.5%Reduced
Caitong International Asset Management Co., Ltd814$1.13K0.00%+814New
US Bancorp931$1.29K0.00%+203+27.9%Added
The PNC Financial Services Group, Inc.1,000$1.39K0.00%00.0%Unchanged
Allworth Financial LP1,000$1.82K0.00%00.0%Unchanged
Royal Bank of Canada1,462$2.00K0.00%−5,073−77.6%Reduced
Nisa Investment Advisors, LLC4,230$5.88K0.00%+3,423+424.2%Added
GF Fund Management Co. Ltd.5,248$7.29K0.00%+945+22.0%Added
CIBC Private Wealth Group, LLC6,833$7.72K0.00%00.0%Unchanged
Amalgamated Bank5,534$8.00K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)6,864$9.54K0.00%−44,221−86.6%Reduced
Atticus Wealth Management, LLC7,425$10.3K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.6,372$12.3K0.00%−457−6.7%Reduced
Mackenzie Financial Corp10,000$13.9K0.00%00.0%Unchanged
Capital Investment Advisors, LLC10,000$13.9K0.00%00.0%Unchanged
Bordeaux Wealth Advisors LLC10,109$14.1K0.00%+10,109New
CWM, LLC10,527$15.0K0.00%+10,262+3,872.5%Added
Camelot Portfolios, LLC11,000$15.3K0.01%+11,000New
Catalyst Funds Management Pty Ltd11,900$16.5K0.00%+11,900New
SIH Partners, LLLP12,173$16.9K0.00%+12,173New
BNP Paribas Arbitrage, SA12,241$17.0K0.00%−11,403−48.2%Reduced
Marex Group plc12,500$17.4K0.00%00.0%Unchanged
California State Teachers Retirement System12,635$17.6K0.00%00.0%Unchanged
Xponance, Inc.12,639$17.6K0.00%+714+6.0%Added
Two Sigma Securities, LLC13,071$18.2K0.00%+13,071New
Principal Financial Group Inc13,989$19.4K0.00%−982−6.6%Reduced
Howard Capital Management Inc.14,165$19.7K0.00%00.0%Unchanged
Prudential Financial Inc15,140$21.0K0.00%+2,150+16.6%Added
Point72 (DIFC) Ltd15,528$21.6K0.00%+15,528New
Ameritas Investment Partners, Inc.15,672$21.8K0.00%00.0%Unchanged
Victory Capital Management Inc19,017$26.4K0.00%+16+0.1%Added
HSBC Holdings PLC20,257$27.7K0.00%−134−0.7%Reduced
Legal & General Group Plc19,958$27.7K0.00%−60−0.3%Reduced
Lee Financial Co20,000$27.8K0.00%00.0%Unchanged
New York State Common Retirement Fund21,100$29.3K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System22,700$31.6K0.00%+2,690+13.4%Added
Ameriprise Financial Inc22,844$31.8K0.00%−149−0.6%Reduced
Cambridge Investment Research Advisors, Inc.23,490$33.0K0.00%00.0%Unchanged
First Manhattan Co28,500$39.6K0.00%00.0%Unchanged
CIBC World Markets Corp38,897$54.1K0.00%+22,492+137.1%Added
Williams & Novak, LLC45,000$56.9K0.06%00.0%Unchanged
China Universal Asset Management Co., Ltd.41,120$57.2K0.01%−2,336−5.4%Reduced
Jain Global LLC45,200$62.8K0.00%+45,200New
Police & Firemen's Retirement System of New Jersey45,678$63.5K0.00%00.0%Unchanged
ProShare Advisors LLC47,195$65.6K0.00%−11,881−20.1%Reduced
Voya Investment Management LLC48,616$67.6K0.00%−2,600−5.1%Reduced
Mariner, LLC58,490$81.3K0.00%+148+0.3%Added
Commonwealth Equity Services, LLC60,069$83.0K0.00%+1,000+1.7%Added
Manufacturers Life Insurance Company, The63,797$88.7K0.00%+786+1.2%Added
Virtus Investment Advisers, Inc.72,957$101.4K0.03%+72,957New
Price T Rowe Associates Inc74,025$103.0K0.00%+8,694+13.3%Added
Creative Planning78,335$108.9K0.00%+57,547+276.8%Added
Leonteq Securities AG79,999$111.2K0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd83,864$116.6K0.01%+83,864New
Corebridge Financial, Inc.85,878$119.4K0.00%−1,272−1.5%Reduced
Intech Investment Management LLC99,912$138.9K0.00%+31,877+46.9%Added
Mirae Asset Global ETFs Holdings Ltd.103,074$143.3K0.00%−5,530−5.1%Reduced
MetLife Investment Management107,711$149.7K0.00%+44,721+71.0%Added
AQR Capital Management LLC107,899$150.0K0.00%+82,545+325.6%Added
Alliancebernstein L.P.108,250$150.5K0.00%00.0%Unchanged
Wells Fargo & Company109,048$151.6K0.00%+5,664+5.5%Added
Franklin Resources Inc116,238$161.6K0.00%+116,238New
BIT Capital GmbH117,062$162.7K0.02%+117,062New
Citigroup Inc133,194$185.1K0.00%−120,098−47.4%Reduced
Deutsche Bank AG134,418$186.8K0.00%−16,665−11.0%Reduced
Privium Fund Management B.V.134,900$187.5K0.05%00.0%Unchanged
EntryPoint Capital, LLC135,897$188.9K0.09%+74,402+121.0%Added
HRT Financial LP139,692$194.0K0.00%+139,692New
Los Angeles Capital Management LLC142,810$198.5K0.00%+5,350+3.9%Added
Chicago Partners Investment Group LLC116,565$221.5K0.01%+521+0.4%Added
Invesco Ltd.159,899$222.3K0.00%+72,544+83.0%Added
XTX Topco Ltd203,129$282.3K0.01%+203,129New
Rhumbline Advisers205,462$285.6K0.00%+13,383+7.0%Added
Citadel Advisors LLC216,611$301.1K0.00%−528,594−70.9%Reduced
Susquehanna International Group, LLP227,472$316.2K0.00%+85,009+59.7%Added
Jefferies Financial Group Inc.245,254$340.9K0.01%+245,254New
Kovitz Investment Group Partners, LLC292,778$407.0K0.00%00.0%Unchanged
Goldman Sachs Group Inc359,007$499.0K0.00%−608,137−62.9%Reduced
UBS Group AG418,132$581.2K0.00%−3,264−0.8%Reduced
Bank of New York Mellon Corp453,420$630.3K0.00%+3,159+0.7%Added
DAFNA Capital Management LLC522,500$726.3K0.21%00.0%Unchanged
Nuveen, LLC546,414$759.5K0.00%+546,414New
Charles Schwab Investment Management Inc547,128$760.5K0.00%+72,871+15.4%Added
Wellington Management Group LLP625,198$869.0K0.00%+39,604+6.8%Added
Bank of America Corp636,842$885.2K0.00%−1,073,461−62.8%Reduced
Alphabet Inc.640,882$890.8K0.06%00.0%Unchanged