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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
191
+1 vs. Q4 2025
Shares held
265.6M
+12.1M (+4.8%) vs. Q4 2025
Total value
$1.18B
−$211.2M (−15.1%) vs. Q4 2025
New holders
35
69 more added
Sold out
34
49 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 191 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ1 2026: $1.18B
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2025.

Institutions holding TSHA in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC79$00.00%+2+2.6%Added
Covestor Ltd27$00.00%+27New
Ameritas Advisory Services, LLC1$40.00%+1New
Assetmark, Inc8$360.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.13$580.00%+13New
MAI Capital Management13$590.00%+5+62.5%Added
IFP Advisors, Inc14$630.00%00.0%Unchanged
SBI Securities Co., Ltd.15$670.00%00.0%Unchanged
True Wealth Design, LLC30$1350.00%00.0%Unchanged
Farther Finance Advisors, LLC55$2370.00%00.0%Unchanged
Root Financial Partners, LLC72$3220.00%+72New
Larson Financial Group LLC128$5720.00%+128New
GAMMA Investing LLC135$6030.00%−141−51.1%Reduced
EverSource Wealth Advisors, LLC141$6300.00%+50+54.9%Added
Rothschild Investment LLC170$7600.00%+100+142.9%Added
Royal Bank of Canada191$1.00K0.00%−6,111−97.0%Reduced
Signaturefd, LLC266$1.19K0.00%+206+343.3%Added
Parallel Advisors, LLC286$1.28K0.00%+6+2.1%Added
Sound Income Strategies, LLC325$1.40K0.00%00.0%Unchanged
Essential Partners LLC327$1.46K0.00%00.0%Unchanged
Jones Financial Companies LLLP561$2.28K0.00%+561New
Quantbot Technologies LP524$2.34K0.00%+524New
Optiver Holding B.V.864$3.86K0.00%−70−7.5%Reduced
Caitong International Asset Management Co., Ltd926$4.14K0.00%−24,651−96.4%Reduced
US Bancorp1,007$4.50K0.00%+95+10.4%Added
The PNC Financial Services Group, Inc.1,043$4.66K0.00%−11−1.0%Reduced
Sterling Capital Management LLC1,411$6.31K0.00%00.0%Unchanged
International Assets Investment Management, LLC2,000$8.62K0.00%00.0%Unchanged
Chung Wu Investment Group, LLC2,000$8.94K0.01%−2,000−50.0%Reduced
Advisor Group Holdings, Inc.2,020$9.03K0.00%+1,743+629.2%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,454$11.0K0.00%+2,454New
Rockefeller Capital Management L.P.5,000$22.4K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec5,000$22.4K0.00%+5,000New
Nisa Investment Advisors, LLC5,107$22.8K0.00%−405−7.3%Reduced
Allworth Financial LP5,443$24.3K0.00%+5,220+2,340.8%Added
GF Fund Management Co. Ltd.6,128$27.4K0.00%+745+13.8%Added
St Germain D J Co Inc9,633$43.1K0.00%00.0%Unchanged
Capital Investment Advisors, LLC10,000$44.7K0.00%00.0%Unchanged
RSM US Wealth Management LLC10,044$44.9K0.00%+10,044New
XTX Topco Ltd10,329$46.2K0.00%+10,329New
Hudson Bay Capital Management LP10,740$48.0K0.00%+10,740New
Neuberger Berman Group LLC10,823$48.4K0.00%+10,823New
CIBC Bancorp USA Inc.11,121$49.7K0.00%+11,121New
Summit Financial, LLC11,148$49.8K0.00%+11,148New
R Squared Ltd11,276$50.4K0.03%+11,276New
Magnetar Financial LLC11,409$51.0K0.00%+11,409New
Y-Intercept (Hong Kong) Ltd11,486$51.3K0.00%+11,486New
CIBC Asset Management Inc11,959$53.5K0.00%00.0%Unchanged
Allegheny Financial Group LTD12,000$53.6K0.01%−14,350−54.5%Reduced
JustInvest LLC12,972$58.0K0.00%+12,972New
Ethic Inc.12,986$58.0K0.00%−9,749−42.9%Reduced
CWM, LLC13,081$58.5K0.00%−12−0.1%Reduced
Virtu Financial LLC13,346$60.0K0.00%+13,346New
Bank of Montreal13,668$61.1K0.00%−40−0.3%Reduced
Mirae Asset Global Investments Co., Ltd.14,287$63.9K0.00%+976+7.3%Added
Catalyst Funds Management Pty Ltd15,100$67.5K0.01%+15,100New
Principal Financial Group Inc16,185$72.3K0.00%+3,362+26.2%Added
Guggenheim Capital LLC16,585$74.1K0.00%+5,474+49.3%Added
Russell Investments Group, Ltd.16,929$75.7K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.17,672$79.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas17,784$79.5K0.00%−2,053−10.3%Reduced
Pictet Asset Management Holding SA19,318$86.4K0.00%00.0%Unchanged
Lee Financial Co20,000$89.4K0.01%00.0%Unchanged
Xponance, Inc.20,033$89.5K0.00%+2,815+16.3%Added
Scientech Research LLC21,040$94.0K0.08%+2,864+15.8%Added
Legato Capital Management LLC21,782$97.4K0.01%+6,759+45.0%Added
Raymond James Financial Inc22,031$98.5K0.00%+3,887+21.4%Added
Cambridge Investment Research Advisors, Inc.22,380$100.0K0.00%+300+1.4%Added
Quadrature Capital Ltd23,499$105.0K0.00%+23,499New
Tower Research Capital LLC (TRC)26,084$116.6K0.00%+25,609+5,391.4%Added
Cetera Investment Advisers28,450$127.2K0.00%+7,296+34.5%Added
Los Angeles Capital Management LLC28,511$127.4K0.00%−4,407−13.4%Reduced
KLP Kapitalforvaltning AS29,300$131.0K0.00%00.0%Unchanged
Envestnet Asset Management Inc33,654$150.4K0.00%+13,476+66.8%Added
J. Goldman & Co LP33,750$150.9K0.01%00.0%Unchanged
Prudential Financial Inc33,820$151.2K0.00%−52,910−61.0%Reduced
Vanguard Investments Australia, Ltd.35,887$160.4K0.00%+35,887New
Arizona State Retirement System37,619$168.2K0.00%−58−0.2%Reduced
E Fund Management Co., Ltd.37,699$168.5K0.01%+37,699New
Aquatic Capital Management LLC39,856$178.2K0.01%+39,856New
Allianz Asset Management GmbH42,400$189.5K0.00%00.0%Unchanged
Williams & Novak, LLC45,000$193.9K0.15%00.0%Unchanged
First Manhattan Co43,500$194.4K0.00%00.0%Unchanged
ProShare Advisors LLC44,267$197.9K0.00%−8,196−15.6%Reduced
Militia Capital Management LLC46,500$207.9K0.05%+46,500New
State of New Jersey Common Pension Fund D46,807$209.2K0.00%+46,807New
Virtus Investment Advisers, Inc.47,095$210.5K0.06%+1,149+2.5%Added
Intech Investment Management LLC47,988$214.5K0.00%−23,081−32.5%Reduced
China Universal Asset Management Co., Ltd.48,609$217.3K0.02%+3,974+8.9%Added
SEI Investments Co51,472$230.1K0.00%+3,614+7.6%Added
NBC Securities, Inc.54,058$241.6K0.02%+1,103+2.1%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.56,577$252.9K0.00%−1,398−2.4%Reduced
Citigroup Inc57,080$255.1K0.00%−5,935−9.4%Reduced
Police & Firemen's Retirement System of New Jersey57,168$255.5K0.00%00.0%Unchanged
Abacus Wealth Partners, LLC58,241$260.3K0.02%+3,068+5.6%Added
Commonwealth Equity Services, LLC58,442$261.2K0.00%+2,785+5.0%Added
VARCOV Co.58,511$261.5K0.10%+58,511New
Creative Planning59,801$267.3K0.00%−3,434−5.4%Reduced
Red Reef Advisors LLC65,950$294.8K0.31%00.0%Unchanged
New York State Common Retirement Fund67,500$301.7K0.00%00.0%Unchanged