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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
131
+13 vs. Q3 2024
Shares held
167.5M
+12.6M (+8.2%) vs. Q3 2024
Total value
$289.8M
−$21.5M (−6.9%) vs. Q3 2024
New holders
28
44 more added
Sold out
15
28 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 131 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ4 2024: $289.8M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2024.

Institutions holding TSHA in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
CWM, LLC265$00.00%−234−46.9%Reduced
Lazard Asset Management LLC154$00.00%00.0%Unchanged
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
SBI Securities Co., Ltd.80$1380.00%+80New
Rothschild Investment LLC130$2250.00%+130New
R Squared Ltd130$2250.00%+130New
Advisor Group Holdings, Inc.134$2330.00%00.0%Unchanged
Sterling Capital Management LLC165$2850.00%00.0%Unchanged
Morton Brown Family Wealth, LLC260$4500.00%00.0%Unchanged
Parallel Advisors, LLC280$4840.00%00.0%Unchanged
Signaturefd, LLC282$4880.00%+107+61.1%Added
CoreCap Advisors, LLC380$6570.00%+380New
Daiwa Securities Group Inc.691$1.00K0.00%00.0%Unchanged
US Bancorp728$1.26K0.00%−132−15.3%Reduced
Lindbrook Capital, LLC770$1.33K0.00%+546+243.8%Added
Nisa Investment Advisors, LLC807$1.40K0.00%+303+60.1%Added
Allworth Financial LP1,000$1.53K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.1,000$1.73K0.00%00.0%Unchanged
Optiver Holding B.V.1,353$2.34K0.00%+747+123.3%Added
GF Fund Management Co. Ltd.4,303$7.44K0.00%+4,303New
Skopos Labs, Inc.4,500$7.79K0.00%+4,500New
Amalgamated Bank5,534$10.0K0.00%00.0%Unchanged
Royal Bank of Canada6,535$11.0K0.00%−29,805−82.0%Reduced
Mirae Asset Global Investments Co., Ltd.6,829$12.0K0.00%−583−7.9%Reduced
Atticus Wealth Management, LLC7,425$12.8K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC6,833$13.2K0.00%00.0%Unchanged
Mackenzie Financial Corp10,000$17.3K0.00%00.0%Unchanged
Capital Investment Advisors, LLC10,000$17.3K0.00%00.0%Unchanged
Xponance, Inc.11,925$20.6K0.00%+1,056+9.7%Added
Two Sigma Investments, LP12,300$21.3K0.00%+12,300New
Marex Group plc12,500$21.6K0.00%00.0%Unchanged
California State Teachers Retirement System12,635$21.9K0.00%00.0%Unchanged
Prudential Financial Inc12,990$22.5K0.00%+1,800+16.1%Added
Howard Capital Management Inc.14,165$24.5K0.00%00.0%Unchanged
Ground Swell Capital, LLC14,660$25.4K0.06%+14,660New
Principal Financial Group Inc14,971$25.9K0.00%−828−5.2%Reduced
Ameritas Investment Partners, Inc.15,672$27.1K0.00%00.0%Unchanged
CIBC World Markets Corp16,405$28.4K0.00%+16,405New
E Fund Management Co., Ltd.17,844$30.9K0.00%+17,844New
Victory Capital Management Inc19,001$32.9K0.00%−1,006−5.0%Reduced
Lee Financial Co20,000$34.6K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System20,010$34.6K0.00%00.0%Unchanged
Legal & General Group Plc20,018$34.6K0.00%00.0%Unchanged
HSBC Holdings PLC20,391$35.6K0.00%+8,076+65.6%Added
Creative Planning20,788$36.0K0.00%+6,670+47.2%Added
New York State Common Retirement Fund21,100$36.5K0.00%00.0%Unchanged
Axq Capital, LP22,432$38.8K0.02%+22,432New
Ameriprise Financial Inc22,993$39.8K0.00%+22,993New
BNP Paribas Arbitrage, SA23,644$40.9K0.00%+23,644New
Cambridge Investment Research Advisors, Inc.23,490$41.0K0.00%−15−0.1%Reduced
AQR Capital Management LLC25,354$43.9K0.00%−44,117−63.5%Reduced
SG Americas Securities, LLC28,498$49.0K0.00%−35,486−55.5%Reduced
First Manhattan Co28,500$49.3K0.00%+28,500New
Virtus ETF Advisers LLC31,597$54.7K0.02%+9,494+43.0%Added
Verition Fund Management LLC34,098$59.0K0.00%+34,098New
Engineers Gate Manager LP35,808$61.9K0.00%+35,808New
China Universal Asset Management Co., Ltd.43,456$75.2K0.01%+4,039+10.2%Added
Williams & Novak, LLC45,000$77.8K0.08%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey45,678$79.0K0.00%+45,678New
Profund Advisors LLC50,242$86.9K0.00%+50,242New
Tower Research Capital LLC (TRC)51,085$88.4K0.00%+37,233+268.8%Added
Voya Investment Management LLC51,216$88.6K0.00%−3,828−7.0%Reduced
Mariner, LLC58,342$100.9K0.00%+45,006+337.5%Added
Commonwealth Equity Services, LLC59,069$102.0K0.00%+31,000+110.4%Added
ProShare Advisors LLC59,076$102.2K0.00%+14,418+32.3%Added
LPL Financial LLC60,000$103.8K0.00%+60,000New
EntryPoint Capital, LLC61,495$106.4K0.04%+34,468+127.5%Added
MetLife Investment Management62,990$109.0K0.00%−13,047−17.2%Reduced
Manufacturers Life Insurance Company, The63,011$109.0K0.00%+2,346+3.9%Added
Price T Rowe Associates Inc65,331$114.0K0.00%+5,612+9.4%Added
Intech Investment Management LLC68,035$117.7K0.00%+25,941+61.6%Added
Aquatic Capital Management LLC78,246$135.4K0.00%+78,246New
Leonteq Securities AG79,999$138.4K0.01%−10.0%Reduced
Corebridge Financial, Inc.87,150$150.8K0.00%−4,948−5.4%Reduced
Invesco Ltd.87,355$151.1K0.00%+1,674+2.0%Added
Wells Fargo & Company103,384$178.9K0.00%+31,457+43.7%Added
Virtu Financial LLC107,544$186.0K0.01%+107,544New
Alliancebernstein L.P.108,250$187.3K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.108,604$187.9K0.00%+20,551+23.3%Added
Chicago Partners Investment Group LLC116,044$224.0K0.01%−2,131−1.8%Reduced
Privium Fund Management B.V.134,900$233.4K0.05%+14,900+12.4%Added
Los Angeles Capital Management LLC137,460$237.8K0.00%−69,532−33.6%Reduced
Marshall Wace, LLP138,111$238.9K0.00%−347,915−71.6%Reduced
Susquehanna International Group, LLP142,463$246.5K0.00%−34,029−19.3%Reduced
Deutsche Bank AG151,083$261.4K0.00%−2,409,201−94.1%Reduced
Millennium Management LLC151,614$262.3K0.00%+151,614New
Jane Street Group, LLC169,575$293.4K0.00%+62,003+57.6%Added
ADAR1 Capital Management, LLC177,707$307.4K0.06%−73,693−29.3%Reduced
Rhumbline Advisers192,079$332.3K0.00%+5,831+3.1%Added
Squarepoint Ops LLC211,842$366.5K0.00%+108,719+105.4%Added
Rafferty Asset Management, LLC252,257$436.4K0.00%+252,257New
Citigroup Inc253,292$438.2K0.00%+120,680+91.0%Added
Kovitz Investment Group Partners, LLC292,778$506.5K0.00%00.0%Unchanged
Barclays PLC335,238$586.7K0.00%+87,958+35.6%Added
UBS Group AG421,396$729.0K0.00%+329,395+358.0%Added
Bank of New York Mellon Corp450,261$779.0K0.00%+111,989+33.1%Added
Charles Schwab Investment Management Inc474,257$820.5K0.00%+11,390+2.5%Added
DAFNA Capital Management LLC522,500$903.9K0.23%+522,500New
Nuveen Asset Management, LLC546,414$945.3K0.00%−20,436−3.6%Reduced
Wellington Management Group LLP585,594$1.01M0.00%+122,402+26.4%Added