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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Taysha Gene Therapies, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
131
+13 vs. Q3 2024
Shares held
167.5M
+12.6M (+8.2%) vs. Q3 2024
Total value
$289.8M
−$21.5M (−6.9%) vs. Q3 2024
New holders
28
44 more added
Sold out
15
28 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 131 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ4 2024: $289.8M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q3 2024.

Institutions holding TSHA in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Marex Group plc12,500$21.6K0.00%00.0%Unchanged
Two Sigma Investments, LP12,300$21.3K0.00%+12,300New
Xponance, Inc.11,925$20.6K0.00%+1,056+9.7%Added
Mackenzie Financial Corp10,000$17.3K0.00%00.0%Unchanged
Capital Investment Advisors, LLC10,000$17.3K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC6,833$13.2K0.00%00.0%Unchanged
Atticus Wealth Management, LLC7,425$12.8K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.6,829$12.0K0.00%−583−7.9%Reduced
Royal Bank of Canada6,535$11.0K0.00%−29,805−82.0%Reduced
Amalgamated Bank5,534$10.0K0.00%00.0%Unchanged
Skopos Labs, Inc.4,500$7.79K0.00%+4,500New
GF Fund Management Co. Ltd.4,303$7.44K0.00%+4,303New
Optiver Holding B.V.1,353$2.34K0.00%+747+123.3%Added
The PNC Financial Services Group, Inc.1,000$1.73K0.00%00.0%Unchanged
Allworth Financial LP1,000$1.53K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC807$1.40K0.00%+303+60.1%Added
Lindbrook Capital, LLC770$1.33K0.00%+546+243.8%Added
US Bancorp728$1.26K0.00%−132−15.3%Reduced
Daiwa Securities Group Inc.691$1.00K0.00%00.0%Unchanged
CoreCap Advisors, LLC380$6570.00%+380New
Signaturefd, LLC282$4880.00%+107+61.1%Added
Parallel Advisors, LLC280$4840.00%00.0%Unchanged
Morton Brown Family Wealth, LLC260$4500.00%00.0%Unchanged
Sterling Capital Management LLC165$2850.00%00.0%Unchanged
Advisor Group Holdings, Inc.134$2330.00%00.0%Unchanged
Rothschild Investment LLC130$2250.00%+130New
R Squared Ltd130$2250.00%+130New
SBI Securities Co., Ltd.80$1380.00%+80New
CWM, LLC265$00.00%−234−46.9%Reduced
Lazard Asset Management LLC154$00.00%00.0%Unchanged
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC0$00.00%−843,200−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−352,684−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−233,560−100.0%Sold out
Franklin Resources Inc0$00.00%−100,795−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−73,857−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−68,264−100.0%Sold out
SEI Investments Co0$00.00%−39,188−100.0%Sold out
Simplex Trading, LLC0$00.00%−38,813−100.0%Sold out
Nebula Research & Development LLC0$00.00%−21,737−100.0%Sold out
Aigen Investment Management, LP0$00.00%−11,189−100.0%Sold out
Oliver Lagore Vanvalin Investment Group0$00.00%−2,800−100.0%Sold out
Global Retirement Partners, LLC0$00.00%−1,006−100.0%Sold out
Clear Street Markets LLC0$00.00%−424−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−198−100.0%Sold out
International Assets Investment Management, LLC0$00.00%−4,020−100.0%Sold out
Ghost Tree Capital, LLC––––Not filed