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Spero Therapeutics, Inc.

SPRO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001701108

No open-market purchases or sales by Spero Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $47.5M in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Spero Therapeutics, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
79
−19 vs. Q1 2022
Shares held
21.0M
+765.5K (+3.8%) vs. Q1 2022
Total value
$15.5M
−$160.1M (−91.2%) vs. Q1 2022
New holders
16
20 more added
Sold out
35
22 more reduced

2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SPRO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 79 institutions
Q1 2021: 95 institutionsQ2 2021: 89 institutionsQ3 2021: 88 institutionsQ4 2021: 84 institutionsQ1 2022: 100 institutionsQ2 2022: 79 institutionsQ3 2022: 69 institutionsQ4 2022: 60 institutionsQ1 2023: 48 institutionsQ2 2023: 56 institutionsQ3 2023: 54 institutionsQ4 2023: 50 institutionsQ1 2024: 54 institutionsQ2 2024: 48 institutionsQ3 2024: 46 institutionsQ4 2024: 50 institutionsQ1 2025: 38 institutionsQ2 2025: 44 institutionsQ3 2025: 47 institutionsQ4 2025: 56 institutionsQ1 2026: 50 institutionsQ2 2026: 59 institutions
Value heldQ2 2022: $15.5M
Q1 2021: $273.1MQ2 2021: $244.2MQ3 2021: $338.3MQ4 2021: $316.7MQ1 2022: $176.1MQ2 2022: $15.5MQ3 2022: $39.7MQ4 2022: $24.6MQ1 2023: $20.6MQ2 2023: $20.8MQ3 2023: $17.2MQ4 2023: $19.6MQ1 2024: $23.7MQ2 2024: $18.0MQ3 2024: $16.5MQ4 2024: $16.1MQ1 2025: $10.9MQ2 2025: $32.1MQ3 2025: $21.3MQ4 2025: $49.2MQ1 2026: $48.3MQ2 2026: $47.5M
Institutions holding SPRO and their total value by quarter
QuarterHoldersValue
Q2 202659$47.5M
Q1 202650$48.3M
Q4 202556$49.2M
Q3 202547$21.3M
Q2 202544$32.1M
Q1 202538$10.9M
Q4 202450$16.1M
Q3 202446$16.5M
Q2 202448$18.0M
Q1 202454$23.7M
Q4 202350$19.6M
Q3 202354$17.2M
Q2 202356$20.8M
Q1 202348$20.6M
Q4 202260$24.6M
Q3 202269$39.7M
Q2 202279$15.5M
Q1 2022100$176.1M
Q4 202184$316.7M
Q3 202188$338.3M
Q2 202189$244.2M
Q1 202195$273.1M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Spero Therapeutics, Inc.; share changes are against Q1 2022.

Institutions holding SPRO in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Engineers Gate Manager LP0$00.00%−10,957−100.0%Sold out
California State Teachers Retirement System0$00.00%−10,256−100.0%Sold out
Radnor Capital Management, LLC0$00.00%−10,000−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−9,048−100.0%Sold out
Amalgamated Bank0$00.00%−3,887−100.0%Sold out
Bedel Financial Consulting, Inc.0$00.00%−3,837−100.0%Sold out
Bollard Group LLC0$00.00%−2,215−100.0%Sold out
Ameritas Investment Partners, Inc.0$00.00%−1,713−100.0%Sold out
Patriot Financial Group Insurance Agency, LLC0$00.00%−1,200−100.0%Sold out
Atlas Capital Advisors LLC0$00.00%−727−100.0%Sold out
TCWP LLC0$00.00%−425−100.0%Sold out
Laurel Wealth Advisors LLC0$00.00%−200−100.0%Sold out
Toth Financial Advisory Corp0$00.00%−172−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−106−100.0%Sold out
Parametric Portfolio Associates LLC––––Not filed
Amalgamated Financial Corp.––––Not filed