Spero Therapeutics, Inc.
SPRO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001701108
No open-market purchases or sales by Spero Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $47.5M in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Spero Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 100
- +17 vs. Q4 2021
- Shares held
- 20.2M
- +451.6K (+2.3%) vs. Q4 2021
- Total value
- $176.1M
- −$140.6M (−44.4%) vs. Q4 2021
- New holders
- 25
- 15 more added
- Sold out
- 8
- 23 more reduced
1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 59 | $47.5M |
| Q1 2026 | 50 | $48.3M |
| Q4 2025 | 56 | $49.2M |
| Q3 2025 | 47 | $21.3M |
| Q2 2025 | 44 | $32.1M |
| Q1 2025 | 38 | $10.9M |
| Q4 2024 | 50 | $16.1M |
| Q3 2024 | 46 | $16.5M |
| Q2 2024 | 48 | $18.0M |
| Q1 2024 | 54 | $23.7M |
| Q4 2023 | 50 | $19.6M |
| Q3 2023 | 54 | $17.2M |
| Q2 2023 | 56 | $20.8M |
| Q1 2023 | 48 | $20.6M |
| Q4 2022 | 60 | $24.6M |
| Q3 2022 | 69 | $39.7M |
| Q2 2022 | 79 | $15.5M |
| Q1 2022 | 100 | $176.1M |
| Q4 2021 | 84 | $316.7M |
| Q3 2021 | 88 | $338.3M |
| Q2 2021 | 89 | $244.2M |
| Q1 2021 | 95 | $273.1M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Spero Therapeutics, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −34,958−100.0% | Sold out |
| IndexIQ Advisors LLC | 0 | $0 | 0.00% | −28,689−100.0% | Sold out |
| MetLife Investment Management | 0 | $0 | 0.00% | −9,977−100.0% | Sold out |
| Metropolitan Life Insurance Co | 0 | $0 | 0.00% | −6,987−100.0% | Sold out |
| Brewin Dolphin Wealth Management Ltd | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Geneos Wealth Management Inc. | 0 | $0 | 0.00% | −590−100.0% | Sold out |
| C M Bidwell & Associates Ltd | 0 | $0 | 0.00% | −372−100.0% | Sold out |
| CoreCap Advisors, LLC | 0 | $0 | 0.00% | −142−100.0% | Sold out |
| Carroll Financial Associates, Inc. | – | – | – | – | Not filed |