Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 264
- +41 vs. Q2 2025
- Shares held
- 70.9M
- +4.57M (+6.9%) vs. Q2 2025
- Total value
- $7.20B
- +$3.01B (+71.8%) vs. Q2 2025
- New holders
- 57
- 99 more added
- Sold out
- 16
- 82 more reduced
4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 305 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| National Asset Management, Inc. | 2,675 | $270.1K | 0.01% | +2,675 | New |
| Toroso Investments, LLC | 2,664 | $269.0K | 0.00% | +2,664 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,568 | $259.3K | 0.00% | +110+4.5% | Added |
| Quantinno Capital Management LP | 2,558 | $258.3K | 0.00% | +2,558 | New |
| Fox Run Management, L.L.C. | 2,517 | $254.2K | 0.04% | +2,517 | New |
| Integrated Wealth Concepts LLC | 2,491 | $251.6K | 0.00% | +2,491 | New |
| Swiss Life Asset Management Ltd | 2,461 | $248.5K | 0.00% | +2,461 | New |
| Centaurus Financial, Inc. | 2,389 | $241.0K | 0.01% | +2,389 | New |
| Guggenheim Capital LLC | 2,285 | $230.8K | 0.00% | +2,285 | New |
| Empowered Funds, LLC | 2,145 | $216.6K | 0.00% | +2,145 | New |
| American Century Companies Inc | 2,077 | $209.8K | 0.00% | +2,077 | New |
| JustInvest LLC | 2,068 | $208.8K | 0.00% | +2,068 | New |
| EntryPoint Capital, LLC | 1,993 | $201.3K | 0.08% | +1,993 | New |
| RWC Asset Management LLP | 1,988 | $200.8K | 0.01% | +1,988 | New |
| ZRC Wealth Management, LLC | 1,971 | $199.1K | 0.07% | 00.0% | Unchanged |
| MAI Capital Management | 1,857 | $187.5K | 0.00% | +1,857 | New |
| Whittier Trust Co | 1,811 | $179.3K | 0.00% | +51+2.9% | Added |
| Tower Research Capital LLC (TRC) | 1,753 | $177.0K | 0.00% | −4,358−71.3% | Reduced |
| KBC Group NV | 1,707 | $172.0K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 1,693 | $171.0K | 0.00% | −188−10.0% | Reduced |
| GF Fund Management Co. Ltd. | 1,429 | $144.3K | 0.00% | −144−9.2% | Reduced |
| Quest Partners LLC | 1,391 | $140.5K | 0.01% | −79−5.4% | Reduced |
| Bayforest Capital Ltd | 1,171 | $118.3K | 0.06% | +1,055+909.5% | Added |
| Advisor Group Holdings, Inc. | 980 | $99.7K | 0.00% | +1+0.1% | Added |
| State of Wyoming | 954 | $96.3K | 0.01% | −111−10.4% | Reduced |
| SRS Capital Advisors, Inc. | 781 | $78.9K | 0.00% | +223+40.0% | Added |
| Bank of Montreal | 715 | $72.2K | 0.00% | +715 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 497 | $50.0K | 0.00% | +76+18.1% | Added |
| Global Retirement Partners, LLC | 400 | $40.4K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 399 | $40.3K | 0.00% | −191−32.4% | Reduced |
| Optiver Holding B.V. | 365 | $36.9K | 0.00% | +144+65.2% | Added |
| Farther Finance Advisors, LLC | 351 | $35.4K | 0.00% | +322+1,110.3% | Added |
| Smartleaf Asset Management LLC | 286 | $28.8K | 0.00% | +141+97.2% | Added |
| GAMMA Investing LLC | 243 | $24.5K | 0.00% | +32+15.2% | Added |
| Signaturefd, LLC | 232 | $23.4K | 0.00% | +8+3.6% | Added |
| Jones Financial Companies LLLP | 234 | $23.2K | 0.00% | +3+1.3% | Added |
| Daiwa Securities Group Inc. | 213 | $22.0K | 0.00% | −16−7.0% | Reduced |
| SBI Securities Co., Ltd. | 198 | $20.0K | 0.00% | +30+17.9% | Added |
| Essential Partners LLC | 198 | $20.0K | 0.01% | +78+65.0% | Added |
| True Wealth Design, LLC | 147 | $14.8K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 146 | $14.7K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 135 | $14.0K | 0.01% | +130+2,600.0% | Added |
| Truvestments Capital LLC | 138 | $13.9K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 131 | $13.2K | 0.00% | +67+104.7% | Added |
| Sterling Capital Management LLC | 127 | $12.8K | 0.00% | −5−3.8% | Reduced |
| AdvisorNet Financial, Inc | 105 | $10.6K | 0.00% | +105 | New |
| Rothschild Investment LLC | 85 | $8.58K | 0.00% | −20−19.0% | Reduced |
| Bessemer Group Inc | 66 | $7.00K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 66 | $6.67K | 0.00% | +1+1.5% | Added |
| WPG Advisers, LLC | 57 | $5.76K | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 42 | $4.24K | 0.00% | +42 | New |
| Aster Capital Management (DIFC) Ltd | 40 | $4.04K | 0.00% | +40 | New |
| Versant Capital Management, Inc | 36 | $3.64K | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 33 | $3.33K | 0.00% | 00.0% | Unchanged |
| ORG Partners LLC | 32 | $3.23K | 0.00% | +8+33.3% | Added |
| Larson Financial Group LLC | 28 | $2.83K | 0.00% | +28 | New |
| Parallel Advisors, LLC | 25 | $2.52K | 0.00% | +6+31.6% | Added |
| J.Safra Asset Management Corp | 20 | $2.02K | 0.00% | +20 | New |
| IFP Advisors, Inc | 19 | $1.92K | 0.00% | +4+26.7% | Added |
| Advisory Services Network, LLC | 19 | $1.92K | 0.00% | +19 | New |
| Bare Financial Services, Inc | 18 | $1.82K | 0.00% | +8+80.0% | Added |
| UMA Financial Services, Inc. | 16 | $1.62K | 0.00% | 00.0% | Unchanged |
| CVA Family Office, LLC | 12 | $1.21K | 0.00% | 00.0% | Unchanged |
| Wealthspire Advisors, LLC | 1 | $101 | 0.00% | +1 | New |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −170,832−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −77,983−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −64,577−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −17,671−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −14,866−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −13,149−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −7,540−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −4,560−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −4,272−100.0% | Sold out |
| Ameriflex Group, Inc. | 0 | $0 | 0.00% | −360−100.0% | Sold out |
| Compagnie Lombard Odier SCmA | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| South State Corp. | 0 | $0 | 0.00% | −71−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −58−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −21−100.0% | Sold out |
| Whipplewood Advisors, LLC | 0 | $0 | 0.00% | −11−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| Norges Bank | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| E Fund Management Co., Ltd. | – | – | – | – | Not filed |
| First Horizon Advisors, Inc. | – | – | – | – | Not filed |