Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 264
- +41 vs. Q2 2025
- Shares held
- 70.9M
- +4.57M (+6.9%) vs. Q2 2025
- Total value
- $7.20B
- +$3.01B (+71.8%) vs. Q2 2025
- New holders
- 57
- 99 more added
- Sold out
- 16
- 82 more reduced
4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wealthspire Advisors, LLC | 1 | $101 | 0.00% | +1 | New |
| CVA Family Office, LLC | 12 | $1.21K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 16 | $1.62K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 18 | $1.82K | 0.00% | +8+80.0% | Added |
| IFP Advisors, Inc | 19 | $1.92K | 0.00% | +4+26.7% | Added |
| Advisory Services Network, LLC | 19 | $1.92K | 0.00% | +19 | New |
| J.Safra Asset Management Corp | 20 | $2.02K | 0.00% | +20 | New |
| Parallel Advisors, LLC | 25 | $2.52K | 0.00% | +6+31.6% | Added |
| Larson Financial Group LLC | 28 | $2.83K | 0.00% | +28 | New |
| ORG Partners LLC | 32 | $3.23K | 0.00% | +8+33.3% | Added |
| Parkside Financial Bank & Trust | 33 | $3.33K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 36 | $3.64K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 40 | $4.04K | 0.00% | +40 | New |
| Quadrant Capital Group LLC | 42 | $4.24K | 0.00% | +42 | New |
| WPG Advisers, LLC | 57 | $5.76K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 66 | $6.67K | 0.00% | +1+1.5% | Added |
| Bessemer Group Inc | 66 | $7.00K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 85 | $8.58K | 0.00% | −20−19.0% | Reduced |
| AdvisorNet Financial, Inc | 105 | $10.6K | 0.00% | +105 | New |
| Sterling Capital Management LLC | 127 | $12.8K | 0.00% | −5−3.8% | Reduced |
| Allworth Financial LP | 131 | $13.2K | 0.00% | +67+104.7% | Added |
| Truvestments Capital LLC | 138 | $13.9K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 135 | $14.0K | 0.01% | +130+2,600.0% | Added |
| US Bancorp | 146 | $14.7K | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 147 | $14.8K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 198 | $20.0K | 0.00% | +30+17.9% | Added |
| Essential Partners LLC | 198 | $20.0K | 0.01% | +78+65.0% | Added |
| Daiwa Securities Group Inc. | 213 | $22.0K | 0.00% | −16−7.0% | Reduced |
| Jones Financial Companies LLLP | 234 | $23.2K | 0.00% | +3+1.3% | Added |
| Signaturefd, LLC | 232 | $23.4K | 0.00% | +8+3.6% | Added |
| GAMMA Investing LLC | 243 | $24.5K | 0.00% | +32+15.2% | Added |
| Smartleaf Asset Management LLC | 286 | $28.8K | 0.00% | +141+97.2% | Added |
| Farther Finance Advisors, LLC | 351 | $35.4K | 0.00% | +322+1,110.3% | Added |
| Optiver Holding B.V. | 365 | $36.9K | 0.00% | +144+65.2% | Added |
| Clearstead Advisors, LLC | 399 | $40.3K | 0.00% | −191−32.4% | Reduced |
| Global Retirement Partners, LLC | 400 | $40.4K | 0.00% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 497 | $50.0K | 0.00% | +76+18.1% | Added |
| Bank of Montreal | 715 | $72.2K | 0.00% | +715 | New |
| SRS Capital Advisors, Inc. | 781 | $78.9K | 0.00% | +223+40.0% | Added |
| State of Wyoming | 954 | $96.3K | 0.01% | −111−10.4% | Reduced |
| Advisor Group Holdings, Inc. | 980 | $99.7K | 0.00% | +1+0.1% | Added |
| Bayforest Capital Ltd | 1,171 | $118.3K | 0.06% | +1,055+909.5% | Added |
| Quest Partners LLC | 1,391 | $140.5K | 0.01% | −79−5.4% | Reduced |
| GF Fund Management Co. Ltd. | 1,429 | $144.3K | 0.00% | −144−9.2% | Reduced |
| Amalgamated Bank | 1,693 | $171.0K | 0.00% | −188−10.0% | Reduced |
| KBC Group NV | 1,707 | $172.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 1,753 | $177.0K | 0.00% | −4,358−71.3% | Reduced |
| Whittier Trust Co | 1,811 | $179.3K | 0.00% | +51+2.9% | Added |
| MAI Capital Management | 1,857 | $187.5K | 0.00% | +1,857 | New |
| ZRC Wealth Management, LLC | 1,971 | $199.1K | 0.07% | 00.0% | Unchanged |
| RWC Asset Management LLP | 1,988 | $200.8K | 0.01% | +1,988 | New |
| EntryPoint Capital, LLC | 1,993 | $201.3K | 0.08% | +1,993 | New |
| JustInvest LLC | 2,068 | $208.8K | 0.00% | +2,068 | New |
| American Century Companies Inc | 2,077 | $209.8K | 0.00% | +2,077 | New |
| Empowered Funds, LLC | 2,145 | $216.6K | 0.00% | +2,145 | New |
| Guggenheim Capital LLC | 2,285 | $230.8K | 0.00% | +2,285 | New |
| Centaurus Financial, Inc. | 2,389 | $241.0K | 0.01% | +2,389 | New |
| Swiss Life Asset Management Ltd | 2,461 | $248.5K | 0.00% | +2,461 | New |
| Integrated Wealth Concepts LLC | 2,491 | $251.6K | 0.00% | +2,491 | New |
| Fox Run Management, L.L.C. | 2,517 | $254.2K | 0.04% | +2,517 | New |
| Quantinno Capital Management LP | 2,558 | $258.3K | 0.00% | +2,558 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,568 | $259.3K | 0.00% | +110+4.5% | Added |
| Toroso Investments, LLC | 2,664 | $269.0K | 0.00% | +2,664 | New |
| National Asset Management, Inc. | 2,675 | $270.1K | 0.01% | +2,675 | New |
| Chicago Partners Investment Group LLC | 2,455 | $278.5K | 0.01% | −660−21.2% | Reduced |
| CWM, LLC | 2,892 | $292.0K | 0.00% | −199−6.4% | Reduced |
| Cerity Partners LLC | 2,964 | $299.3K | 0.00% | +2,964 | New |
| Jane Street Group, LLC | 2,968 | $299.7K | 0.00% | +2,968 | New |
| Cim Investment Mangement Inc | 2,993 | $302.3K | 0.08% | +2,993 | New |
| Susquehanna International Group, LLP | 3,104 | $313.5K | 0.00% | −74,158−96.0% | Reduced |
| JGP Global Gestao de Recursos Ltda. | 3,253 | $328.5K | 0.19% | −571−14.9% | Reduced |
| Two Sigma Advisers, LP | 3,300 | $333.3K | 0.00% | −6,400−66.0% | Reduced |
| Capstone Investment Advisors, LLC | 3,497 | $353.2K | 0.00% | +3,497 | New |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 3,541 | $357.6K | 0.01% | −2,094−37.2% | Reduced |
| D. E. Shaw & Co., Inc. | 3,585 | $362.0K | 0.00% | −20,693−85.2% | Reduced |
| Mariner, LLC | 3,597 | $363.3K | 0.00% | −724−16.8% | Reduced |
| FORA Capital, LLC | 3,599 | $363.5K | 0.06% | +3,599 | New |
| Freestone Capital Holdings, LLC | 3,700 | $373.7K | 0.01% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 3,897 | $394.0K | 0.03% | −2,200−36.1% | Reduced |
| LPL Financial LLC | 3,990 | $402.9K | 0.00% | −815−17.0% | Reduced |
| Xponance, Inc. | 4,162 | $420.3K | 0.00% | −110−2.6% | Reduced |
| The PNC Financial Services Group, Inc. | 4,217 | $425.9K | 0.00% | −1,326−23.9% | Reduced |
| Ameritas Investment Partners, Inc. | 4,365 | $440.8K | 0.01% | −1,181−21.3% | Reduced |
| Mackenzie Financial Corp | 4,398 | $444.2K | 0.00% | −13−0.3% | Reduced |
| O'Shaughnessy Asset Management, LLC | 4,836 | $488.4K | 0.00% | +1,360+39.1% | Added |
| Gotham Asset Management, LLC | 4,855 | $490.3K | 0.00% | +4+0.1% | Added |
| Quantbot Technologies LP | 4,981 | $503.0K | 0.01% | +4,981 | New |
| Public Employees Retirement Association of Colorado | 5,463 | $552.0K | 0.00% | 00.0% | Unchanged |
| DnB Asset Management AS | 5,528 | $558.3K | 0.00% | +5,528 | New |
| Oxford Asset Management LLP | 5,538 | $559.3K | 0.18% | +5,538 | New |
| CIBC Bancorp USA Inc. | 5,569 | $562.4K | 0.00% | +5,569 | New |
| Jasper Ridge Partners, L.P. | 5,639 | $569.5K | 0.01% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 6,307 | $636.9K | 0.00% | +6,307 | New |
| Exchange Traded Concepts, LLC | 6,386 | $644.9K | 0.01% | +6,386 | New |
| Virginia Retirement Systems Et Al | 6,700 | $676.6K | 0.00% | +6,700 | New |
| Virtus Investment Advisers, Inc. | 7,052 | $712.2K | 0.20% | 00.0% | Unchanged |
| Inceptionr LLC | 7,482 | $755.6K | 0.18% | +7,482 | New |
| Leo Wealth, LLC | 7,867 | $794.5K | 0.10% | −5,578−41.5% | Reduced |
| E. Ohman J:or Asset Management AB | 8,213 | $829.4K | 0.02% | 00.0% | Unchanged |
| Aigen Investment Management, LP | 8,225 | $830.6K | 0.13% | +4,011+95.2% | Added |