Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 264
- +41 vs. Q2 2025
- Shares held
- 70.9M
- +4.57M (+6.9%) vs. Q2 2025
- Total value
- $7.20B
- +$3.01B (+71.8%) vs. Q2 2025
- New holders
- 57
- 99 more added
- Sold out
- 16
- 82 more reduced
4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Readystate Asset Management LP | 8,365 | $844.8K | 0.04% | −16,301−66.1% | Reduced |
| Entropy Technologies, LP | 8,502 | $858.6K | 0.06% | +8,502 | New |
| Rockefeller Capital Management L.P. | 8,868 | $895.6K | 0.00% | +8,868 | New |
| Bellevue Group AG | 9,053 | $914.3K | 0.02% | −11,853−56.7% | Reduced |
| Fiduciary Trust Co | 10,000 | $1.01M | 0.01% | 00.0% | Unchanged |
| Toth Financial Advisory Corp | 10,000 | $1.01M | 0.11% | 00.0% | Unchanged |
| Cannon Financial Strategists, Inc. | 10,000 | $1.01M | 0.14% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,726 | $1.08M | 0.00% | +1,074+11.1% | Added |
| KLP Kapitalforvaltning AS | 11,000 | $1.11M | 0.00% | +800+7.8% | Added |
| ProShare Advisors LLC | 11,299 | $1.14M | 0.00% | −2,237−16.5% | Reduced |
| China Universal Asset Management Co., Ltd. | 11,642 | $1.18M | 0.10% | −1,136−8.9% | Reduced |
| SummitTX Capital, L.P. | 11,869 | $1.20M | 0.05% | −13,583−53.4% | Reduced |
| Allianz Asset Management GmbH | 12,100 | $1.22M | 0.00% | 00.0% | Unchanged |
| Fred Alger Management, LLC | 12,335 | $1.25M | 0.00% | +12,335 | New |
| Profund Advisors LLC | 12,457 | $1.26M | 0.04% | +1,203+10.7% | Added |
| Principal Financial Group Inc | 12,598 | $1.27M | 0.00% | −469−3.6% | Reduced |
| Teacher Retirement System of Texas | 12,960 | $1.31M | 0.01% | +188+1.5% | Added |
| Citigroup Inc | 13,080 | $1.32M | 0.00% | −21,244−61.9% | Reduced |
| Nisa Investment Advisors, LLC | 13,254 | $1.34M | 0.01% | +12,000+956.9% | Added |
| Engineers Gate Manager LP | 13,775 | $1.39M | 0.02% | −3,901−22.1% | Reduced |
| Advisors Asset Management, Inc. | 14,178 | $1.43M | 0.02% | +582+4.3% | Added |
| Great West Life Assurance Co | 14,395 | $1.45M | 0.00% | +2,817+24.3% | Added |
| Stifel Financial Corp | 14,455 | $1.46M | 0.00% | −3,722−20.5% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 14,606 | $1.48M | 0.01% | +2,247+18.2% | Added |
| State Board of Administration of Florida Retirement System | 14,650 | $1.48M | 0.00% | −20−0.1% | Reduced |
| STRS Ohio | 14,800 | $1.49M | 0.01% | −2,600−14.9% | Reduced |
| Handelsbanken Fonder AB | 15,521 | $1.57M | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 15,614 | $1.58M | 0.01% | +1,780+12.9% | Added |
| Los Angeles Capital Management LLC | 16,721 | $1.69M | 0.01% | +12,849+331.8% | Added |
| Quantedge Capital Pte Ltd | 17,800 | $1.80M | 0.98% | +17,800 | New |
| Schroder Investment Management Group | 18,042 | $1.82M | 0.00% | +424+2.4% | Added |
| Captrust Financial Advisors | 18,258 | $1.84M | 0.00% | +787+4.5% | Added |
| SG Americas Securities, LLC | 19,554 | $1.98M | 0.01% | +13,369+216.2% | Added |
| Burkehill Global Management, LP | 20,000 | $2.02M | 0.11% | +20,000 | New |
| EFG Asset Management (North America) Corp. | 20,269 | $2.05M | 0.26% | +20,269 | New |
| State of New Jersey Common Pension Fund D | 20,919 | $2.11M | 0.01% | −9,454−31.1% | Reduced |
| Wedge Capital Management L L P | 22,244 | $2.25M | 0.04% | −7,747−25.8% | Reduced |
| Intech Investment Management LLC | 24,312 | $2.46M | 0.02% | −3,131−11.4% | Reduced |
| Wellington Management Group LLP | 24,477 | $2.47M | 0.00% | +2,052+9.2% | Added |
| Creative Planning | 24,945 | $2.52M | 0.00% | +7,723+44.8% | Added |
| Standard Life Aberdeen plc | 26,740 | $2.70M | 0.00% | −40,917−60.5% | Reduced |
| Voleon Capital Management LP | 26,897 | $2.72M | 0.07% | +26,897 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 27,122 | $2.74M | 0.00% | −5,229−16.2% | Reduced |
| Dimensional Fund Advisors LP | 28,378 | $2.87M | 0.00% | +28,378 | New |
| Dark Forest Capital Management LP | 28,639 | $2.89M | 0.11% | −6,190−17.8% | Reduced |
| Lazard Asset Management LLC | 30,239 | $3.05M | 0.00% | −69,206−69.6% | Reduced |
| Samsara BioCapital, LLC | 30,285 | $3.06M | 0.40% | −20,191−40.0% | Reduced |
| MetLife Investment Management | 30,362 | $3.07M | 0.01% | −2,033−6.3% | Reduced |
| Penserra Capital Management LLC | 30,436 | $3.07M | 0.04% | +30,436 | New |
| SEI Investments Co | 31,658 | $3.20M | 0.00% | −1,487−4.5% | Reduced |
| Alps Advisors Inc | 33,000 | $3.33M | 0.02% | −1,178−3.4% | Reduced |
| Silvercrest Asset Management Group LLC | 34,084 | $3.44M | 0.02% | −14,691−30.1% | Reduced |
| Rhenman & Partners Asset Management AB | 35,000 | $3.53M | 0.39% | +35,000 | New |
| Jain Global LLC | 35,110 | $3.55M | 0.05% | +31,202+798.4% | Added |
| Cinctive Capital Management LP | 35,156 | $3.55M | 0.18% | −35,781−50.4% | Reduced |
| Canada Pension Plan Investment Board | 37,000 | $3.74M | 0.00% | +37,000 | New |
| Trexquant Investment LP | 37,161 | $3.75M | 0.04% | +30,078+424.7% | Added |
| Harbor Capital Advisors, Inc. | 37,205 | $3.76M | 0.29% | −49,341−57.0% | Reduced |
| HighVista Strategies LLC | 37,482 | $3.79M | 0.93% | +9,414+33.5% | Added |
| Kennedy Capital Management, Inc. | 39,575 | $4.00M | 0.09% | −17,642−30.8% | Reduced |
| State of Wisconsin Investment Board | 40,776 | $4.12M | 0.01% | +5,068+14.2% | Added |
| Aquatic Capital Management LLC | 42,490 | $4.29M | 0.08% | +38,537+974.9% | Added |
| Castleark Management LLC | 42,539 | $4.30M | 0.12% | +42,539 | New |
| Hillsdale Investment Management Inc. | 42,600 | $4.30M | 0.13% | +42,600 | New |
| Victory Capital Management Inc | 42,883 | $4.33M | 0.00% | +26,642+164.0% | Added |
| Raymond James Financial Inc | 44,093 | $4.45M | 0.00% | +33,547+318.1% | Added |
| Hennion & Walsh Asset Management, Inc. | 44,731 | $4.52M | 0.16% | −6,348−12.4% | Reduced |
| Wells Fargo & Company | 47,134 | $4.76M | 0.00% | +4,766+11.2% | Added |
| WCM Investment Management, LLC | 47,733 | $4.80M | 0.01% | +47,733 | New |
| Harvest Investment Services, LLC | 48,140 | $4.86M | 0.98% | +32,674+211.3% | Added |
| PFM Health Sciences, LP | 48,162 | $4.86M | 0.41% | +48,162 | New |
| California State Teachers Retirement System | 48,934 | $4.94M | 0.01% | +6,017+14.0% | Added |
| Nan Fung Group Holdings Ltd | 49,120 | $4.96M | 8.32% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 49,571 | $5.01M | 0.50% | +4,181+9.2% | Added |
| Granahan Investment Management Inc | 49,728 | $5.02M | 0.21% | +8,556+20.8% | Added |
| Walleye Capital LLC | 50,181 | $5.07M | 0.04% | +50,181 | New |
| Rafferty Asset Management, LLC | 55,734 | $5.63M | 0.02% | +4,123+8.0% | Added |
| Legal & General Group Plc | 57,376 | $5.79M | 0.00% | +4,695+8.9% | Added |
| EAM Investors, LLC | 58,480 | $5.81M | 0.67% | +58,480 | New |
| TD Asset Management Inc | 59,564 | $6.02M | 0.00% | +3,564+6.4% | Added |
| Manufacturers Life Insurance Company, The | 60,917 | $6.15M | 0.01% | −7,215−10.6% | Reduced |
| Panagora Asset Management Inc | 64,614 | $6.53M | 0.03% | −54,852−45.9% | Reduced |
| Prudential Financial Inc | 73,010 | $7.37M | 0.01% | +65,915+929.0% | Added |
| New York State Common Retirement Fund | 75,131 | $7.59M | 0.01% | +16,513+28.2% | Added |
| AQR Capital Management LLC | 79,780 | $8.06M | 0.01% | +30,740+62.7% | Added |
| First Trust Advisors LP | 80,903 | $8.17M | 0.01% | +7,189+9.8% | Added |
| Rhumbline Advisers | 82,068 | $8.29M | 0.01% | −5,458−6.2% | Reduced |
| Axiom Investors LLC | 83,031 | $8.39M | 0.06% | +30,571+58.3% | Added |
| Neuberger Berman Group LLC | 85,117 | $8.60M | 0.01% | −1,022−1.2% | Reduced |
| PDT Partners, LLC | 86,136 | $8.70M | 0.55% | −11,502−11.8% | Reduced |
| StemPoint Capital LP | 91,444 | $9.23M | 1.86% | −85,308−48.3% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 101,372 | $10.2M | 0.02% | +5,855+6.1% | Added |
| Swiss National Bank | 102,300 | $10.3M | 0.01% | +11,700+12.9% | Added |
| Ensign Peak Advisors, Inc | 111,544 | $11.3M | 0.02% | +93,885+531.7% | Added |
| Deutsche Bank AG | 116,742 | $11.8M | 0.00% | +79,963+217.4% | Added |
| Nuveen, LLC | 117,964 | $11.9M | 0.00% | −3,891−3.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 121,260 | $12.2M | 0.04% | +6,142+5.3% | Added |
| Royal Bank of Canada | 125,786 | $12.7M | 0.00% | −70,450−35.9% | Reduced |
| Man Group plc | 129,330 | $13.1M | 0.03% | +129,330 | New |
| Citadel Advisors LLC | 132,626 | $13.4M | 0.01% | +132,626 | New |