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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
165
0 vs. Q1 2024
Shares held
69.3M
+1.31M (+1.9%) vs. Q1 2024
Total value
$2.85B
−$98.1M (−3.3%) vs. Q1 2024
New holders
24
63 more added
Sold out
24
54 more reduced

2 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 165 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ2 2024: $2.85B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2024.

Institutions holding RYTM in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Manufacturers Life Insurance Company, The49,291$2.02M0.00%+1,667+3.5%Added
Legal & General Group Plc49,771$2.04M0.00%+2,355+5.0%Added
Barclays PLC53,631$2.20M0.00%−73,905−57.9%Reduced
Alliancebernstein L.P.61,070$2.51M0.00%+7,640+14.3%Added
Wedge Capital Management L L P63,197$2.59M0.05%−10,676−14.5%Reduced
UBS Group AG65,942$2.71M0.00%−105,623−61.6%Reduced
Rafferty Asset Management, LLC72,562$2.98M0.01%−146,095−66.8%Reduced
Rhumbline Advisers83,063$3.41M0.00%+6,339+8.3%Added
Clearbridge Investments, LLC88,108$3.62M0.00%−1,896−2.1%Reduced
Swiss National Bank88,700$3.64M0.00%−4,600−4.9%Reduced
First Trust Advisors LP91,010$3.74M0.00%+91,010New
Bank of America Corp92,043$3.78M0.00%−19,071−17.2%Reduced
Rice Hall James & Associates, LLC93,081$3.82M0.23%+3,355+3.7%Added
Hennion & Walsh Asset Management, Inc.96,378$3.96M0.20%+9,411+10.8%Added
Lord, Abbett & Co. LLC102,591$4.21M0.01%−178,566−63.5%Reduced
AQR Capital Management LLC103,830$4.26M0.01%+32,831+46.2%Added
Algert Global LLC104,132$4.28M0.14%+35,084+50.8%Added
Marshall Wace, LLP106,809$4.39M0.01%+87,059+440.8%Added
Standard Life Aberdeen plc112,804$4.63M0.01%+112,804New
Ghost Tree Capital, LLC117,388$4.82M1.68%−7,612−6.1%Reduced
JPMorgan Chase & Co140,146$5.75M0.00%+85,642+157.1%Added
Jane Street Group, LLC146,500$6.02M0.01%+120,182+456.7%Added
Nuveen Asset Management, LLC149,119$6.12M0.00%+6,384+4.5%Added
Samsara BioCapital, LLC172,647$7.09M1.48%00.0%Unchanged
Silverarc Capital Management, LLC184,662$7.58M1.87%+886+0.5%Added
Bank of New York Mellon Corp191,871$7.88M0.00%+24,033+14.3%Added
Wellington Management Group LLP202,326$8.31M0.00%+8,803+4.5%Added
Assenagon Asset Management S.A.229,491$9.42M0.02%−56,160−19.7%Reduced
Franklin Resources Inc232,677$9.55M0.00%+11,772+5.3%Added
UBS Asset Management Americas Inc236,431$9.71M0.00%+29,451+14.2%Added
Artisan Partners Limited Partnership271,267$11.1M0.02%−154−0.1%Reduced
Candriam Luxembourg S.C.A.271,398$11.1M0.07%+271,398New
Invesco Ltd.276,700$11.4M0.00%+188,495+213.7%Added
Nisa Investment Advisors, LLC374,347$15.4M0.10%+229,056+157.7%Added
Canada Pension Plan Investment Board417,000$17.1M0.02%−160,000−27.7%Reduced
National Bank of Canada404,242$17.2M0.03%+36,725+10.0%Added
Charles Schwab Investment Management Inc427,958$17.6M0.00%+21,213+5.2%Added
Voloridge Investment Management, LLC462,188$19.0M0.07%−11,267−2.4%Reduced
Cormorant Asset Management, LP475,000$19.5M1.13%−75,000−13.6%Reduced
Morgan Stanley475,651$19.5M0.00%+292,781+160.1%Added
Northern Trust Corp499,448$20.5M0.00%−3,407−0.7%Reduced
Opaleye Management Inc.515,000$21.1M4.83%00.0%Unchanged
Price T Rowe Associates Inc525,942$21.6M0.00%+44,409+9.2%Added
Janus Henderson Group PLC593,642$24.4M0.01%−27,785−4.5%Reduced
OrbiMed Advisors LLC704,842$28.9M0.62%00.0%Unchanged
Pictet Asset Management Holding SA801,796$32.9M0.04%−409,883−33.8%Reduced
Checkpoint Capital L.P.922,100$37.9M22.82%+96,600+11.7%Added
Healthcare of Ontario Pension Plan Trust Fund967,243$39.7M0.12%+236,600+32.4%Added
Alkeon Capital Management LLC1,000,000$41.1M0.21%+1,000,000New
Driehaus Capital Management LLC1,182,370$48.5M0.47%+326,865+38.2%Added
Commodore Capital LP1,225,000$50.3M3.43%+175,000+16.7%Added
Geode Capital Management, LLC1,252,689$51.4M0.00%+71,984+6.1%Added
Rock Springs Capital Management LP1,280,493$52.6M1.59%−242,400−15.9%Reduced
Polar Capital Holdings Plc1,500,000$61.6M0.36%00.0%Unchanged
Federated Hermes, Inc.1,660,784$68.2M0.16%−3130.0%Reduced
State Street Corp2,003,882$82.3M0.00%−1,009,956−33.5%Reduced
Frazier Life Sciences Management, L.P.2,371,304$97.4M4.55%+181,125+8.3%Added
NEA Management Company, LLC2,909,956$119.5M8.99%00.0%Unchanged
Vanguard Group Inc3,360,695$138.0M0.00%+56,549+1.7%Added
Perceptive Advisors LLC3,446,579$141.5M3.42%+178,000+5.4%Added
Goldman Sachs Group Inc5,288,635$217.2M0.04%+177,034+3.5%Added
Ra Capital Management, L.P.6,084,412$249.8M3.30%+754,000+14.1%Added
Baker Bros. Advisors LP6,398,365$262.7M3.36%00.0%Unchanged
BlackRock Inc.6,741,923$276.8M0.01%+212,277+3.3%Added
Primecap Management Co7,312,391$300.2M0.22%−435,200−5.6%Reduced
Jefferies Financial Group Inc.0$00.00%−68,566−100.0%Sold out
Altium Capital Management LP0$00.00%−57,271−100.0%Sold out
Exome Asset Management LLC0$00.00%−45,603−100.0%Sold out
Alps Advisors Inc0$00.00%−42,419−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−26,436−100.0%Sold out
American International Group, Inc.0$00.00%−26,318−100.0%Sold out
Twinbeech Capital LP0$00.00%−22,714−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−16,331−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−15,355−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−13,355−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−10,706−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−10,462−100.0%Sold out
E Fund Management Co., Ltd.0$00.00%−10,333−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−8,600−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−7,400−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−6,738−100.0%Sold out
Aigen Investment Management, LP0$00.00%−6,479−100.0%Sold out
Citadel Advisors LLC0$00.00%−4,098−100.0%Sold out
Quantbot Technologies LP0$00.00%−3,600−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−2,812−100.0%Sold out
Lazard Asset Management LLC0$00.00%−1,733−100.0%Sold out
Fernwood Investment Management, LLC0$00.00%−1,554−100.0%Sold out
Truvestments Capital LLC0$00.00%−216−100.0%Sold out
Nelson, Van Denburg & Campbell Wealth Management Group, LLC0$00.00%−10−100.0%Sold out
Credit Suisse AG––––Not filed
Cutler Group LP––––Not filed