Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 115
- +14 vs. Q3 2022
- Shares held
- 62.3M
- +2.82M (+4.7%) vs. Q3 2022
- Total value
- $1.81B
- +$369.1M (+25.5%) vs. Q3 2022
- New holders
- 26
- 42 more added
- Sold out
- 12
- 28 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 773,028 | $22.5M | 0.00% | −597,920−43.6% | Reduced |
| Janus Henderson Group PLC | 1,240,153 | $36.1M | 0.03% | −320,930−20.6% | Reduced |
| Polar Capital Holdings Plc | 1,250,000 | $36.4M | 0.29% | +535,261+74.9% | Added |
| Rock Springs Capital Management LP | 1,760,865 | $51.3M | 1.23% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 1,894,000 | $55.2M | 3.43% | 00.0% | Unchanged |
| Alkeon Capital Management LLC | 2,238,262 | $65.2M | 0.48% | +533,262+31.3% | Added |
| Vanguard Group Inc | 2,596,314 | $75.6M | 0.00% | +362,042+16.2% | Added |
| State Street Corp | 3,180,698 | $92.6M | 0.01% | +52,793+1.7% | Added |
| BlackRock Inc. | 3,723,714 | $108.4M | 0.00% | +186,215+5.3% | Added |
| NEA Management Company, LLC | 4,909,956 | $143.0M | 8.03% | −2,3500.0% | Reduced |
| Goldman Sachs Group Inc | 5,201,792 | $151.5M | 0.04% | +424,614+8.9% | Added |
| Ra Capital Management, L.P. | 5,516,067 | $160.6M | 3.26% | +45,000+0.8% | Added |
| Federated Hermes, Inc. | 6,304,482 | $183.6M | 0.51% | −2,3840.0% | Reduced |
| Baker Bros. Advisors LP | 6,354,608 | $185.0M | 1.11% | +291,906+4.8% | Added |
| Primecap Management Co | 6,911,142 | $201.3M | 0.18% | −115,750−1.6% | Reduced |
| Walleye Capital LLC | 0 | $0 | 0.00% | −191,373−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −83,796−100.0% | Sold out |
| Prosight Management, LP | 0 | $0 | 0.00% | −80,000−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −72,375−100.0% | Sold out |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −65,000−100.0% | Sold out |
| Raymond James & Associates | 0 | $0 | 0.00% | −22,600−100.0% | Sold out |
| Harvest Investment Services, LLC | 0 | $0 | 0.00% | −13,941−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −5,992−100.0% | Sold out |
| Cutler Group LP | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| IFP Advisors, Inc | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −567−100.0% | Sold out |
| Hantz Financial Services, Inc. | 0 | $0 | 0.00% | −115−100.0% | Sold out |