Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 187
- −1 vs. Q1 2026
- Shares held
- 106.7M
- +8.19M (+8.3%) vs. Q1 2026
- Total value
- $393.5M
- +$51.3M (+15.0%) vs. Q1 2026
- New holders
- 22
- 64 more added
- Sold out
- 23
- 67 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 16,562,498 | $61.1M | 0.06% | 00.0% | Unchanged |
| BlackRock, Inc. | 9,602,041 | $35.4M | 0.00% | +1,100,333+12.9% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 8,348,746 | $30.8M | 0.20% | +2,101,919+33.6% | Added |
| State Street Corp | 7,576,460 | $28.0M | 0.00% | +1,231,335+19.4% | Added |
| T. Rowe Price Investment Management, Inc. | 5,237,332 | $19.3M | 0.01% | −244,561−4.5% | Reduced |
| Vanguard Capital Management LLC | 4,522,640 | $16.7M | 0.00% | +48,478+1.1% | Added |
| Balyasny Asset Management LLC | 3,969,082 | $14.6M | 0.03% | −154,283−3.7% | Reduced |
| Goldman Sachs Group Inc | 3,430,518 | $12.7M | 0.00% | +2,460,093+253.5% | Added |
| Casdin Capital, LLC | 3,167,175 | $11.7M | 0.58% | 00.0% | Unchanged |
| Woodline Partners LP | 3,003,904 | $11.1M | 0.03% | +5910.0% | Added |
| UBS Group AG | 2,794,689 | $10.3M | 0.00% | −93,729−3.2% | Reduced |
| Geode Capital Management, LLC | 2,712,446 | $10.0M | 0.00% | −31,254−1.1% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 2,412,984 | $8.90M | 0.01% | −527,809−17.9% | Reduced |
| Nikko Asset Management Americas, Inc. | 2,407,018 | $8.86M | 0.11% | −533,775−18.2% | Reduced |
| Citadel Advisors LLC | 2,054,543 | $7.58M | 0.00% | +1,718,185+510.8% | Added |
| ADAR1 Capital Management, LLC | 1,997,552 | $7.37M | 0.35% | +24,270+1.2% | Added |
| FMR LLC | 1,761,884 | $6.50M | 0.00% | −7,592−0.4% | Reduced |
| Two Sigma Investments, LP | 1,524,511 | $5.63M | 0.00% | −48,300−3.1% | Reduced |
| Redmile Group, LLC | 1,389,632 | $5.13M | 0.34% | −201,200−12.6% | Reduced |
| Farallon Capital Management, L.L.C. | 1,240,843 | $4.58M | 0.03% | 00.0% | Unchanged |
| Jump Financial, LLC | 1,240,429 | $4.58M | 0.04% | +1,240,429 | New |
| Bank of America Corp | 981,335 | $3.62M | 0.00% | +404,331+70.1% | Added |
| Vanguard Portfolio Management LLC | 961,826 | $3.55M | 0.00% | +99,622+11.6% | Added |
| Charles Schwab Investment Management Inc | 927,538 | $3.42M | 0.00% | +10,326+1.1% | Added |
| Northern Trust Corp | 912,597 | $3.37M | 0.00% | +25,881+2.9% | Added |
| JPMorgan Chase & Co | 810,095 | $3.01M | 0.00% | −34,059−4.0% | Reduced |
| Greenwich Wealth Management LLC | 768,001 | $2.83M | 0.10% | +18,000+2.4% | Added |
| Vanguard Fiduciary Trust Co | 764,633 | $2.82M | 0.00% | +47,631+6.6% | Added |
| Morgan Stanley | 708,963 | $2.62M | 0.00% | +69,506+10.9% | Added |
| Alessandra Capital Management, LLC | 666,603 | $2.46M | 1.74% | +241,093+56.7% | Added |
| D. E. Shaw & Co., Inc. | 648,940 | $2.39M | 0.00% | −744,681−53.4% | Reduced |
| Susquehanna International Group, LLP | 648,479 | $2.39M | 0.00% | −67,350−9.4% | Reduced |
| Point72 Asset Management, L.P. | 533,553 | $1.97M | 0.00% | +533,553 | New |
| Moore Capital Management, LP | 500,000 | $1.84M | 0.04% | 00.0% | Unchanged |
| Chelsea Counsel Co | 449,060 | $1.66M | 0.70% | −13,280−2.9% | Reduced |
| Millennium Management LLC | 427,097 | $1.58M | 0.00% | +427,097 | New |
| HighTower Advisors, LLC | 340,365 | $1.26M | 0.00% | +1100.0% | Added |
| Dimensional Fund Advisors LP | 304,678 | $1.12M | 0.00% | +156+0.1% | Added |
| Wellington Management Group LLP | 304,444 | $1.12M | 0.00% | +26,324+9.5% | Added |
| Nuveen, LLC | 275,931 | $1.02M | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 251,747 | $928.9K | 0.00% | −67,803−21.2% | Reduced |
| Bank of New York Mellon Corp | 246,344 | $909.0K | 0.00% | −20,875−7.8% | Reduced |
| Davy Global Fund Management Ltd | 225,799 | $833.2K | 0.05% | +20,410+9.9% | Added |
| Marshall Wace, LLP | 216,841 | $800.1K | 0.00% | +74,884+52.8% | Added |
| XTX Topco Ltd | 215,708 | $796.0K | 0.01% | +58,426+37.1% | Added |
| Jain Global LLC | 215,218 | $794.2K | 0.01% | +215,218 | New |
| Jupiter Asset Management Ltd | 209,490 | $773.0K | 0.00% | +209,490 | New |
| Swiss National Bank | 208,300 | $768.6K | 0.00% | +29,700+16.6% | Added |
| PEAK6 LLC | 208,057 | $767.7K | 0.02% | +208,057 | New |
| Citigroup Inc | 195,664 | $722.0K | 0.00% | +148,432+314.3% | Added |
| Green Alpha Advisors, LLC | 185,023 | $682.7K | 0.46% | −6,148−3.2% | Reduced |
| Keystone Financial Group | 166,510 | $614.4K | 0.04% | +500+0.3% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 162,338 | $599.5K | 0.00% | +39,875+32.6% | Added |
| Price T Rowe Associates Inc | 162,325 | $599.0K | 0.00% | +28,570+21.4% | Added |
| HRT Financial LP | 161,510 | $595.0K | 0.00% | −451,259−73.6% | Reduced |
| California State Teachers Retirement System | 157,049 | $579.5K | 0.00% | +70,576+81.6% | Added |
| Bollard Group LLC | 151,136 | $558.0K | 0.02% | −210,000−58.1% | Reduced |
| Rafferty Asset Management, LLC | 145,275 | $536.1K | 0.00% | −70,307−32.6% | Reduced |
| Alliancebernstein L.P. | 150,300 | $523.0K | 0.00% | +27,840+22.7% | Added |
| Invesco Ltd. | 140,308 | $517.7K | 0.00% | +43,433+44.8% | Added |
| Concurrent Investment Advisors, LLC | 131,722 | $486.1K | 0.00% | +57,545+77.6% | Added |
| ExodusPoint Capital Management, LP | 118,464 | $437.1K | 0.00% | +118,464 | New |
| AQR Capital Management LLC | 117,998 | $435.4K | 0.00% | −436,937−78.7% | Reduced |
| Virtus Investment Advisers, Inc. | 117,909 | $435.1K | 0.10% | +51,401+77.3% | Added |
| Renaissance Technologies LLC | 117,412 | $433.3K | 0.00% | −623,627−84.2% | Reduced |
| Rhumbline Advisers | 116,754 | $430.8K | 0.00% | +2,485+2.2% | Added |
| FIL Ltd | 115,206 | $425.1K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 114,472 | $422.4K | 0.00% | −42,968−27.3% | Reduced |
| Steward Partners Investment Advisory, LLC | 108,290 | $399.6K | 0.00% | −9,166−7.8% | Reduced |
| Palumbo Wealth Management LLC | 103,801 | $383.0K | 0.08% | +1,555+1.5% | Added |
| Milestone Asset Management, LLC | 100,035 | $369.1K | 0.06% | +100,035 | New |
| TD Asset Management Inc | 94,148 | $347.4K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 92,174 | $340.1K | 0.00% | +25,750+38.8% | Added |
| Rockefeller Capital Management L.P. | 90,735 | $334.8K | 0.00% | −666−0.7% | Reduced |
| Barclays PLC | 88,058 | $324.9K | 0.00% | +24,285+38.1% | Added |
| Squarepoint Ops LLC | 88,029 | $324.8K | 0.00% | −6,037−6.4% | Reduced |
| Commonwealth Equity Services, LLC | 87,310 | $322.2K | 0.00% | +70,873+431.2% | Added |
| UBS Asset Management Americas Inc | 85,300 | $314.8K | 0.00% | 00.0% | Unchanged |
| Los Angeles Capital Management LLC | 82,305 | $303.7K | 0.00% | +29,690+56.4% | Added |
| Profund Advisors LLC | 72,624 | $268.0K | 0.01% | −23,182−24.2% | Reduced |
| Legal & General Group Plc | 66,444 | $245.2K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 66,101 | $243.9K | 0.00% | +31,688+92.1% | Added |
| Bridgeway Capital Management, LLC | 64,800 | $239.1K | 0.00% | −70,000−51.9% | Reduced |
| Jupiter Topco LLC | 60,900 | $224.4K | 0.00% | +60,900 | New |
| Engineers Gate Manager LP | 59,133 | $218.2K | 0.00% | −51,215−46.4% | Reduced |
| Vanguard Asset Management, Ltd | 59,021 | $217.8K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 58,922 | $217.0K | 0.00% | +58,922 | New |
| Wiley Bros.-Aintree Capital, LLC | 57,460 | $210.6K | 0.00% | −2,010−3.4% | Reduced |
| MetLife Investment Management | 56,192 | $207.3K | 0.00% | +11,984+27.1% | Added |
| Russell Investments Group, Ltd. | 50,994 | $188.2K | 0.00% | −13,279−20.7% | Reduced |
| Ameriprise Financial Inc | 49,941 | $184.3K | 0.00% | +357+0.7% | Added |
| Mutual Advisors, LLC | 45,000 | $166.1K | 0.00% | −200−0.4% | Reduced |
| Vanguard Global Advisers, LLC | 44,269 | $163.4K | 0.00% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 43,663 | $161.1K | 0.00% | −3,230−6.9% | Reduced |
| IvyRock Asset Management (HK) Ltd | 41,800 | $154.2K | 0.09% | 00.0% | Unchanged |
| CI Private Wealth, LLC | 39,078 | $144.2K | 0.00% | −2,143−5.2% | Reduced |
| Jones Financial Companies LLLP | 40,867 | $140.2K | 0.00% | +560+1.4% | Added |
| State of New Jersey Common Pension Fund D | 33,569 | $123.9K | 0.00% | +2,724+8.8% | Added |
| Cambridge Investment Research Advisors, Inc. | 32,854 | $122.0K | 0.00% | +20,517+166.3% | Added |
| Crestwood Advisors Group LLC | 32,041 | $118.2K | 0.00% | −333−1.0% | Reduced |