Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 121
- −4 vs. Q1 2025
- Shares held
- 58.7M
- −1.70M (−2.8%) vs. Q1 2025
- Total value
- $145.0M
- +$24.6M (+20.4%) vs. Q1 2025
- New holders
- 29
- 36 more added
- Sold out
- 33
- 35 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 15,062,498 | $37.2M | 1.74% | 00.0% | Unchanged |
| T. Rowe Price Investment Management, Inc. | 6,484,787 | $16.0M | 0.01% | +2,341,691+56.5% | Added |
| BlackRock, Inc. | 4,485,828 | $11.1M | 0.00% | +179,617+4.2% | Added |
| FMR LLC | 3,744,427 | $9.25M | 0.00% | −2,808−0.1% | Reduced |
| Vanguard Group Inc | 3,627,510 | $8.96M | 0.00% | −13,838−0.4% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,322,669 | $5.74M | 0.04% | −772,503−25.0% | Reduced |
| Redmile Group, LLC | 2,074,350 | $5.12M | 0.55% | 00.0% | Unchanged |
| MWG Management Limited | 1,792,210 | $4.43M | 8.53% | 00.0% | Unchanged |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,594,518 | $3.94M | 0.00% | −1,331,505−45.5% | Reduced |
| Nikko Asset Management Americas, Inc. | 1,589,117 | $3.89M | 0.04% | −1,336,906−45.7% | Reduced |
| Casdin Capital, LLC | 1,567,175 | $3.87M | 0.35% | +1,200,000+326.8% | Added |
| Geode Capital Management, LLC | 1,510,749 | $3.73M | 0.00% | −15,781−1.0% | Reduced |
| State Street Corp | 1,239,337 | $3.06M | 0.00% | +94,032+8.2% | Added |
| Greenwich Wealth Management LLC | 846,201 | $2.09M | 0.10% | +27,200+3.3% | Added |
| Schonfeld Strategic Advisors LLC | 818,518 | $2.02M | 0.02% | +818,518 | New |
| Farallon Capital Management, L.L.C. | 750,000 | $1.85M | 0.01% | 00.0% | Unchanged |
| Morgan Stanley | 587,676 | $1.45M | 0.00% | +232,500+65.5% | Added |
| Citadel Advisors LLC | 521,508 | $1.29M | 0.00% | +521,508 | New |
| Charles Schwab Investment Management Inc | 518,628 | $1.28M | 0.00% | +14,931+3.0% | Added |
| Northern Trust Corp | 512,234 | $1.27M | 0.00% | −15,075−2.9% | Reduced |
| Moore Capital Management, LP | 500,000 | $1.24M | 0.02% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 482,728 | $1.19M | 0.00% | +340,109+238.5% | Added |
| AQR Capital Management LLC | 424,355 | $1.05M | 0.00% | +180,560+74.1% | Added |
| Fred Alger Management, LLC | 383,194 | $946.5K | 0.00% | +383,194 | New |
| Bollard Group LLC | 361,136 | $892.0K | 0.02% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 258,423 | $638.3K | 0.00% | −347−0.1% | Reduced |
| Renaissance Technologies LLC | 223,400 | $551.8K | 0.00% | −224,200−50.1% | Reduced |
| Bridgeway Capital Management, LLC | 214,800 | $530.6K | 0.01% | +214,800 | New |
| Chelsea Counsel Co | 208,210 | $514.3K | 0.26% | 00.0% | Unchanged |
| Nuveen, LLC | 207,894 | $513.5K | 0.00% | +148,492+250.0% | Added |
| Goldman Sachs Group Inc | 207,008 | $511.3K | 0.00% | −44,391−17.7% | Reduced |
| UBS Group AG | 195,327 | $482.5K | 0.00% | +77,647+66.0% | Added |
| Simplex Trading, LLC | 193,615 | $478.0K | 0.01% | +185,239+2,211.5% | Added |
| Palumbo Wealth Management LLC | 183,358 | $452.9K | 0.14% | +87,896+92.1% | Added |
| Alliancebernstein L.P. | 167,420 | $413.5K | 0.00% | +91,420+120.3% | Added |
| Bank of New York Mellon Corp | 162,052 | $400.3K | 0.00% | +6,060+3.9% | Added |
| Millennium Management LLC | 147,996 | $365.6K | 0.00% | −1,631,949−91.7% | Reduced |
| Bank of America Corp | 144,511 | $356.9K | 0.00% | +31,585+28.0% | Added |
| Levin Capital Strategies, L.P. | 140,000 | $345.8K | 0.03% | +105,000+300.0% | Added |
| XTX Topco Ltd | 133,490 | $329.7K | 0.01% | +133,490 | New |
| Deutsche Bank AG | 125,445 | $309.8K | 0.00% | −1,401−1.1% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 119,856 | $296.0K | 0.00% | +85,938+253.4% | Added |
| FIL Ltd | 117,270 | $289.7K | 0.00% | −3,747−3.1% | Reduced |
| Barclays PLC | 114,802 | $283.6K | 0.00% | +43,378+60.7% | Added |
| Diametric Capital, LP | 105,530 | $260.7K | 0.14% | +105,530 | New |
| Wells Fargo & Company | 101,151 | $249.8K | 0.00% | +10,332+11.4% | Added |
| National Bank of Canada | 98,807 | $244.0K | 0.00% | +98,807 | New |
| Rhumbline Advisers | 97,972 | $242.0K | 0.00% | +16,072+19.6% | Added |
| Green Alpha Advisors, LLC | 78,994 | $195.1K | 0.19% | −4,473−5.4% | Reduced |
| Mutual Advisors, LLC | 45,200 | $190.3K | 0.00% | +45,200 | New |
| Price T Rowe Associates Inc | 65,320 | $162.0K | 0.00% | −1,501,872−95.8% | Reduced |
| HRT Financial LP | 64,167 | $158.0K | 0.00% | +64,167 | New |
| Prelude Capital Management, LLC | 41,288 | $102.0K | 0.01% | +41,288 | New |
| MetLife Investment Management | 39,014 | $96.4K | 0.00% | +39,014 | New |
| Jaffetilchin Investment Partners, LLC | 37,744 | $93.2K | 0.01% | +37,744 | New |
| Axq Capital, LP | 37,587 | $92.8K | 0.03% | +37,587 | New |
| Ieq Capital, LLC | 35,830 | $88.5K | 0.00% | +948+2.7% | Added |
| Squarepoint Ops LLC | 35,826 | $88.5K | 0.00% | +35,826 | New |
| CWM, LLC | 35,761 | $88.0K | 0.00% | +15,295+74.7% | Added |
| Citigroup Inc | 34,759 | $85.9K | 0.00% | −7,543−17.8% | Reduced |
| Davy Global Fund Management Ltd | 33,660 | $83.1K | 0.01% | −56,210−62.5% | Reduced |
| JPMorgan Chase & Co | 33,035 | $81.6K | 0.00% | −2,628−7.4% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 26,007 | $80.9K | 0.00% | +13,777+112.6% | Added |
| Crestwood Advisors Group LLC | 31,687 | $78.3K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 30,810 | $76.1K | 0.00% | −24,136−43.9% | Reduced |
| SG Americas Securities, LLC | 27,919 | $69.0K | 0.00% | −23,537−45.7% | Reduced |
| Jane Street Group, LLC | 27,145 | $67.0K | 0.00% | +27,145 | New |
| BNP Paribas Arbitrage, SA | 26,735 | $66.0K | 0.00% | −4,587−14.6% | Reduced |
| China Universal Asset Management Co., Ltd. | 26,370 | $65.1K | 0.01% | +61+0.2% | Added |
| Kingsview Wealth Management, LLC | 25,000 | $61.8K | 0.00% | +25,000 | New |
| JustInvest LLC | 23,191 | $57.3K | 0.00% | +7,954+52.2% | Added |
| TD Asset Management Inc | 22,910 | $56.6K | 0.00% | −23,524−50.7% | Reduced |
| HighTower Advisors, LLC | 21,354 | $52.7K | 0.00% | −292−1.3% | Reduced |
| Federation des caisses Desjardins du Quebec | 21,200 | $52.4K | 0.00% | +21,200 | New |
| Manufacturers Life Insurance Company, The | 20,979 | $51.8K | 0.00% | −3,945−15.8% | Reduced |
| Voya Investment Management LLC | 17,222 | $42.5K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 17,092 | $42.2K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 16,871 | $41.7K | 0.00% | −1,323−7.3% | Reduced |
| Clarius Group, LLC | 16,080 | $39.7K | 0.00% | 00.0% | Unchanged |
| Prime Capital Investment Advisors, LLC | 16,031 | $39.6K | 0.00% | −8,230−33.9% | Reduced |
| Commonwealth Equity Services, LLC | 14,942 | $37.0K | 0.00% | +14,942 | New |
| CIBC World Markets Inc. | 14,326 | $35.4K | 0.00% | −2,689−15.8% | Reduced |
| Invesco Ltd. | 13,662 | $33.7K | 0.00% | −1,174−7.9% | Reduced |
| JTC Employer Solutions Trusteee Ltd | 13,249 | $33.0K | 0.00% | +13,249 | New |
| Virtu Financial LLC | 12,545 | $31.0K | 0.00% | +12,545 | New |
| R Squared Ltd | 12,519 | $30.9K | 0.02% | +12,519 | New |
| Tower Research Capital LLC (TRC) | 12,246 | $30.2K | 0.00% | +2,337+23.6% | Added |
| State Board of Administration of Florida Retirement System | 11,420 | $28.2K | 0.00% | 00.0% | Unchanged |
| Eqis Capital Management, Inc. | 10,432 | $25.8K | 0.00% | +10,432 | New |
| Creative Planning | 10,145 | $25.1K | 0.00% | +10,145 | New |
| Fogel Capital Management, Inc. | 10,000 | $24.7K | 0.01% | +10,000 | New |
| New York State Common Retirement Fund | 8,434 | $20.8K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5,145 | $13.0K | 0.00% | +3,505+213.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 5,072 | $12.5K | 0.00% | +683+15.6% | Added |
| Legal & General Group Plc | 4,899 | $12.1K | 0.00% | −1,016−17.2% | Reduced |
| Nisa Investment Advisors, LLC | 4,236 | $10.5K | 0.00% | +3,921+1,244.8% | Added |
| Ameritas Investment Partners, Inc. | 3,901 | $9.63K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 3,358 | $8.29K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 1,957 | $5.00K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 1,576 | $3.89K | 0.00% | +1,518+2,617.2% | Added |