Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2023
Institutional positions in Prime Medicine, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 83
- +5 vs. Q2 2023
- Shares held
- 49.5M
- +3.39M (+7.3%) vs. Q2 2023
- Total value
- $472.3M
- −$203.4M (−30.1%) vs. Q2 2023
- New holders
- 11
- 35 more added
- Sold out
- 6
- 15 more reduced
1 institution that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 11,862,498 | $113.2M | 7.27% | 00.0% | Unchanged |
| Vanguard Group Inc | 3,951,793 | $37.7M | 0.00% | +617,310+18.5% | Added |
| FMR LLC | 3,922,416 | $37.4M | 0.00% | −116,803−2.9% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,634,848 | $34.7M | 0.03% | +571,097+18.6% | Added |
| Nikko Asset Management Americas, Inc. | 3,634,848 | $34.6M | 0.41% | +570,232+18.6% | Added |
| BlackRock Inc. | 3,334,525 | $31.8M | 0.00% | +445,309+15.4% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,622,429 | $25.0M | 0.19% | +173,230+7.1% | Added |
| Price T Rowe Associates Inc | 2,173,371 | $20.7M | 0.00% | −160,460−6.9% | Reduced |
| FIL Ltd | 1,805,558 | $17.2M | 0.02% | 00.0% | Unchanged |
| MWG Management Limited | 1,792,210 | $17.1M | 16.57% | 00.0% | Unchanged |
| State Street Corp | 1,686,001 | $16.1M | 0.00% | +1,080,802+178.6% | Added |
| Redmile Group, LLC | 1,324,350 | $12.6M | 0.60% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,028,466 | $9.81M | 0.06% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $8.45M | 0.19% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 846,637 | $8.08M | 0.00% | +306,329+56.7% | Added |
| EcoR1 Capital, LLC | 600,000 | $5.72M | 0.19% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 470,304 | $4.49M | 1.37% | 00.0% | Unchanged |
| Moore Capital Management, LP | 446,733 | $4.26M | 0.12% | 00.0% | Unchanged |
| Greenwich Wealth Management LLC | 439,021 | $4.19M | 0.44% | +231,021+111.1% | Added |
| Casdin Capital, LLC | 367,175 | $3.50M | 0.39% | 00.0% | Unchanged |
| Northern Trust Corp | 332,958 | $3.18M | 0.00% | +50,527+17.9% | Added |
| Bank of America Corp | 302,642 | $2.89M | 0.00% | +155,127+105.2% | Added |
| Charles Schwab Investment Management Inc | 292,570 | $2.79M | 0.00% | +151,426+107.3% | Added |
| Ensign Peak Advisors, Inc | 150,000 | $1.43M | 0.00% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 128,876 | $1.23M | 0.01% | +128,876 | New |
| Janus Henderson Group PLC | 120,946 | $1.15M | 0.00% | −443,908−78.6% | Reduced |
| Bank of New York Mellon Corp | 115,389 | $1.10M | 0.00% | +12,176+11.8% | Added |
| Nuveen Asset Management, LLC | 106,922 | $1.02M | 0.00% | −16,273−13.2% | Reduced |
| TD Asset Management Inc | 104,542 | $997.3K | 0.00% | +37,471+55.9% | Added |
| Two Sigma Investments, LP | 92,993 | $887.2K | 0.00% | +92,993 | New |
| Barclays PLC | 65,140 | $621.4K | 0.00% | +57,261+726.8% | Added |
| Manufacturers Life Insurance Company, The | 64,660 | $616.9K | 0.00% | +6,259+10.7% | Added |
| Goldman Sachs Group Inc | 58,911 | $562.0K | 0.00% | +58,911 | New |
| Citigroup Inc | 56,193 | $536.1K | 0.00% | +42,032+296.8% | Added |
| Rhumbline Advisers | 50,959 | $486.1K | 0.00% | +3,896+8.3% | Added |
| UBS Group AG | 43,772 | $417.6K | 0.00% | −55,267−55.8% | Reduced |
| Morgan Stanley | 42,791 | $408.2K | 0.00% | −15,138−26.1% | Reduced |
| Green Alpha Advisors, LLC | 37,815 | $360.8K | 0.28% | +25,429+205.3% | Added |
| Brandywine Managers, LLC | 32,977 | $314.6K | 0.53% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 31,840 | $303.8K | 0.00% | +5,300+20.0% | Added |
| Wells Fargo & Company | 31,317 | $298.8K | 0.00% | +15,020+92.2% | Added |
| JPMorgan Chase & Co | 27,014 | $257.7K | 0.00% | −3,658−11.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 23,016 | $219.6K | 0.00% | +4,145+22.0% | Added |
| Profund Advisors LLC | 21,995 | $209.8K | 0.01% | +21,995 | New |
| Oppenheimer & Co Inc | 21,537 | $205.5K | 0.00% | +6,152+40.0% | Added |
| MetLife Investment Management | 21,262 | $202.8K | 0.00% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 21,299 | $201.0K | 0.00% | −23−0.1% | Reduced |
| Deutsche Bank AG | 20,555 | $196.1K | 0.00% | +2,743+15.4% | Added |
| American International Group, Inc. | 19,743 | $188.3K | 0.00% | +703+3.7% | Added |
| Penserra Capital Management LLC | 18,468 | $176.0K | 0.00% | +10,361+127.8% | Added |
| Principal Financial Group Inc | 18,041 | $172.1K | 0.00% | +12+0.1% | Added |
| Envestnet Asset Management Inc | 16,616 | $158.5K | 0.00% | +16,616 | New |
| New York State Common Retirement Fund | 16,316 | $155.7K | 0.00% | +332+2.1% | Added |
| Voya Investment Management LLC | 16,160 | $154.2K | 0.00% | +417+2.6% | Added |
| Clarius Group, LLC | 16,080 | $153.4K | 0.01% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 15,490 | $147.8K | 0.00% | +15,490 | New |
| Red Lighthouse Investment Management, LLC | 14,950 | $142.6K | 0.07% | 00.0% | Unchanged |
| Virtu Financial LLC | 12,466 | $119.0K | 0.01% | +12,466 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $108.9K | 0.00% | +190+1.7% | Added |
| Walleye Capital LLC | 10,700 | $102.1K | 0.00% | +10,700 | New |
| Brown Brothers Harriman & Co | 10,065 | $96.0K | 0.00% | 00.0% | Unchanged |
| Sandia Investment Management LP | 10,000 | $95.4K | 0.03% | 00.0% | Unchanged |
| California State Teachers Retirement System | 8,729 | $83.3K | 0.00% | −4,430−33.7% | Reduced |
| Advisor Group Holdings, Inc. | 7,962 | $75.9K | 0.00% | +1,559+24.3% | Added |
| Citadel Advisors LLC | 6,524 | $62.2K | 0.00% | +6,524 | New |
| Amalgamated Bank | 6,014 | $57.0K | 0.00% | +1,262+26.6% | Added |
| ORG Partners LLC | 5,270 | $50.3K | 0.01% | 00.0% | Unchanged |
| Royal Bank of Canada | 4,953 | $47.0K | 0.00% | +1,374+38.4% | Added |
| Legal & General Group Plc | 4,524 | $43.1K | 0.00% | −267−5.6% | Reduced |
| Ameritas Investment Partners, Inc. | 3,901 | $37.2K | 0.00% | +634+19.4% | Added |
| Tower Research Capital LLC (TRC) | 3,528 | $33.7K | 0.00% | +385+12.2% | Added |
| Allspring Global Investments Holdings, LLC | 3,067 | $29.3K | 0.00% | −8,374−73.2% | Reduced |
| Metropolitan Life Insurance Co | 2,203 | $21.0K | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 1,670 | $15.0K | 0.00% | +66+4.1% | Added |
| First Horizon Advisors, Inc. | 1,031 | $9.84K | 0.00% | −524−33.7% | Reduced |
| Comerica Bank | 779 | $7.43K | 0.00% | +779 | New |
| Chelsea Counsel Co | 600 | $5.72K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 346 | $3.30K | 0.00% | 00.0% | Unchanged |
| Benjamin Edwards Inc | 321 | $3.00K | 0.00% | 00.0% | Unchanged |
| Grove Bank & Trust | 77 | $735 | 0.00% | +77 | New |
| Massmutual Trust Co FSB | 25 | $239 | 0.00% | −9−26.5% | Reduced |
| Nisa Investment Advisors, LLC | 20 | $191 | 0.00% | −13−39.4% | Reduced |
| Covestor Ltd | 8 | $0 | 0.00% | −1−11.1% | Reduced |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −397,004−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −256,560−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −55,888−100.0% | Sold out |
| Levin Capital Strategies, L.P. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −12,254−100.0% | Sold out |
| CWM, LLC | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Endurance Wealth Management, Inc. | – | – | – | – | Not filed |