Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Prime Medicine, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 105
- +22 vs. Q3 2023
- Shares held
- 48.7M
- −826.1K (−1.7%) vs. Q3 2023
- Total value
- $431.4M
- −$40.8M (−8.6%) vs. Q3 2023
- New holders
- 34
- 26 more added
- Sold out
- 12
- 27 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 11,862,498 | $105.1M | 4.87% | 00.0% | Unchanged |
| Vanguard Group Inc | 4,054,911 | $35.9M | 0.00% | +103,118+2.6% | Added |
| FMR LLC | 3,925,346 | $34.8M | 0.00% | +2,930+0.1% | Added |
| BlackRock Inc. | 3,778,618 | $33.5M | 0.00% | +444,093+13.3% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,519,029 | $31.2M | 0.02% | −115,819−3.2% | Reduced |
| Nikko Asset Management Americas, Inc. | 3,519,029 | $31.2M | 0.30% | −115,819−3.2% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 3,138,270 | $27.8M | 0.16% | +515,841+19.7% | Added |
| Price T Rowe Associates Inc | 2,221,159 | $19.7M | 0.00% | +47,788+2.2% | Added |
| MWG Management Limited | 1,792,210 | $15.9M | 13.36% | 00.0% | Unchanged |
| Redmile Group, LLC | 1,324,350 | $11.7M | 0.42% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,028,466 | $9.11M | 0.10% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 887,503 | $7.86M | 0.00% | +40,866+4.8% | Added |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $7.84M | 0.14% | 00.0% | Unchanged |
| State Street Corp | 759,758 | $6.73M | 0.00% | −926,243−54.9% | Reduced |
| Greenwich Wealth Management LLC | 513,001 | $4.54M | 0.45% | +73,980+16.9% | Added |
| Bank of America Corp | 470,596 | $4.17M | 0.00% | +167,954+55.5% | Added |
| Samsara BioCapital, LLC | 470,304 | $4.17M | 0.65% | 00.0% | Unchanged |
| Casdin Capital, LLC | 367,175 | $3.25M | 0.32% | 00.0% | Unchanged |
| Bollard Group LLC | 361,136 | $3.20M | 0.11% | +361,136 | New |
| Northern Trust Corp | 344,927 | $3.06M | 0.00% | +11,969+3.6% | Added |
| Charles Schwab Investment Management Inc | 296,188 | $2.62M | 0.00% | +3,618+1.2% | Added |
| Two Sigma Investments, LP | 268,362 | $2.38M | 0.01% | +175,369+188.6% | Added |
| Morgan Stanley | 211,734 | $1.88M | 0.00% | +168,943+394.8% | Added |
| Ensign Peak Advisors, Inc | 150,000 | $1.33M | 0.00% | 00.0% | Unchanged |
| FIL Ltd | 146,942 | $1.30M | 0.00% | −1,658,616−91.9% | Reduced |
| Vestmark Advisory Solutions, Inc. | 144,288 | $1.28M | 0.06% | +144,288 | New |
| Millennium Management LLC | 134,544 | $1.19M | 0.00% | +134,544 | New |
| Woodline Partners LP | 120,060 | $1.06M | 0.01% | +120,060 | New |
| Susquehanna Portfolio Strategies, LLC | 116,887 | $1.04M | 0.02% | +116,887 | New |
| Bank of New York Mellon Corp | 114,246 | $1.01M | 0.00% | −1,143−1.0% | Reduced |
| Nuveen Asset Management, LLC | 108,093 | $957.7K | 0.00% | +1,171+1.1% | Added |
| TrueMark Investments, LLC | 75,030 | $664.8K | 0.66% | +75,030 | New |
| Sphera Funds Management Ltd. | 73,980 | $655.5K | 0.12% | +73,980 | New |
| Squarepoint Ops LLC | 71,523 | $633.7K | 0.00% | +56,033+361.7% | Added |
| Walleye Capital LLC | 68,306 | $605.2K | 0.01% | +57,606+538.4% | Added |
| Manufacturers Life Insurance Company, The | 64,547 | $571.9K | 0.00% | −113−0.2% | Reduced |
| HRT Financial LP | 59,116 | $523.0K | 0.00% | +59,116 | New |
| Jane Street Group, LLC | 55,219 | $489.2K | 0.00% | +55,219 | New |
| Barclays PLC | 54,235 | $480.5K | 0.00% | −10,905−16.7% | Reduced |
| Renaissance Technologies LLC | 53,292 | $472.0K | 0.00% | +53,292 | New |
| TD Asset Management Inc | 52,742 | $467.3K | 0.00% | −51,800−49.5% | Reduced |
| Goldman Sachs Group Inc | 51,149 | $453.2K | 0.00% | −7,762−13.2% | Reduced |
| Rhumbline Advisers | 50,858 | $450.6K | 0.00% | −101−0.2% | Reduced |
| Bank of Montreal | 45,000 | $430.2K | 0.00% | +45,000 | New |
| Susquehanna International Group, LLP | 46,585 | $412.7K | 0.00% | +46,585 | New |
| Two Sigma Advisers, LP | 46,000 | $407.6K | 0.00% | +46,000 | New |
| JPMorgan Chase & Co | 45,519 | $403.3K | 0.00% | +18,505+68.5% | Added |
| Royce & Associates LP | 39,837 | $353.0K | 0.00% | +39,837 | New |
| Alliancebernstein L.P. | 37,360 | $331.0K | 0.00% | +5,520+17.3% | Added |
| EntryPoint Capital, LLC | 35,235 | $312.2K | 0.30% | +35,235 | New |
| Brandywine Managers, LLC | 32,977 | $292.2K | 0.32% | 00.0% | Unchanged |
| UBS Group AG | 31,412 | $278.3K | 0.00% | −12,360−28.2% | Reduced |
| Green Alpha Advisors, LLC | 29,538 | $261.7K | 0.19% | −8,277−21.9% | Reduced |
| Trexquant Investment LP | 26,983 | $239.1K | 0.01% | +26,983 | New |
| Envestnet Asset Management Inc | 22,370 | $198.2K | 0.00% | +5,754+34.6% | Added |
| PEAK6 Investments LLC | 22,000 | $194.9K | 0.01% | +22,000 | New |
| Mirae Asset Global Investments Co., Ltd. | 21,301 | $188.7K | 0.00% | −1,715−7.5% | Reduced |
| MetLife Investment Management | 21,262 | $188.4K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 21,011 | $186.2K | 0.00% | +17,483+495.5% | Added |
| HighTower Advisors, LLC | 21,117 | $185.0K | 0.00% | −182−0.9% | Reduced |
| Oppenheimer & Co Inc | 20,598 | $182.5K | 0.00% | −939−4.4% | Reduced |
| Vestal Point Capital, LP | 20,306 | $179.9K | 0.02% | +20,306 | New |
| Deutsche Bank AG | 20,101 | $178.1K | 0.00% | −454−2.2% | Reduced |
| Levin Capital Strategies, L.P. | 20,000 | $177.2K | 0.02% | +20,000 | New |
| American International Group, Inc. | 19,663 | $174.2K | 0.00% | −80−0.4% | Reduced |
| Principal Financial Group Inc | 17,890 | $158.5K | 0.00% | −151−0.8% | Reduced |
| STRS Ohio | 17,100 | $151.0K | 0.00% | +17,100 | New |
| Voya Investment Management LLC | 16,160 | $143.2K | 0.00% | 00.0% | Unchanged |
| Clarius Group, LLC | 16,080 | $142.5K | 0.01% | 00.0% | Unchanged |
| Red Lighthouse Investment Management, LLC | 14,950 | $132.5K | 0.06% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 13,570 | $120.2K | 0.00% | +5,608+70.4% | Added |
| ProShare Advisors LLC | 12,756 | $113.0K | 0.00% | +12,756 | New |
| Royal Bank of Canada | 12,173 | $109.0K | 0.00% | +7,220+145.8% | Added |
| CIBC World Markets Inc. | 12,261 | $109.0K | 0.00% | +12,261 | New |
| Gsa Capital Partners LLP | 12,195 | $108.0K | 0.01% | +12,195 | New |
| Amundi | 11,770 | $106.0K | 0.00% | +11,770 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $101.2K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 11,258 | $99.7K | 0.02% | +11,258 | New |
| Citigroup Inc | 10,935 | $96.9K | 0.00% | −45,258−80.5% | Reduced |
| Wells Fargo & Company | 10,229 | $90.6K | 0.00% | −21,088−67.3% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 10,193 | $90.3K | 0.01% | +10,193 | New |
| SG Americas Securities, LLC | 10,128 | $90.0K | 0.00% | +10,128 | New |
| Brown Brothers Harriman & Co | 10,065 | $89.2K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 8,440 | $74.8K | 0.00% | −7,876−48.3% | Reduced |
| California State Teachers Retirement System | 6,511 | $57.7K | 0.00% | −2,218−25.4% | Reduced |
| Amalgamated Bank | 5,613 | $50.0K | 0.00% | −401−6.7% | Reduced |
| ORG Partners LLC | 5,270 | $46.7K | 0.01% | 00.0% | Unchanged |
| Chelsea Counsel Co | 5,000 | $44.3K | 0.02% | +4,400+733.3% | Added |
| Legal & General Group Plc | 4,336 | $38.4K | 0.00% | −188−4.2% | Reduced |
| Ameritas Investment Partners, Inc. | 3,901 | $34.6K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,203 | $19.5K | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 1,732 | $15.0K | 0.00% | +62+3.7% | Added |
| Comerica Bank | 1,314 | $11.6K | 0.00% | +535+68.7% | Added |
| Advisory Services Network, LLC | 1,153 | $10.2K | 0.00% | +1,153 | New |
| Sandia Investment Management LP | 1,084 | $9.60K | 0.01% | −8,916−89.2% | Reduced |
| First Horizon Advisors, Inc. | 810 | $7.18K | 0.00% | −221−21.4% | Reduced |
| Fairman Group, LLC | 500 | $4.43K | 0.00% | +500 | New |
| Daiwa Securities Group Inc. | 398 | $4.00K | 0.00% | +398 | New |
| Benjamin Edwards Inc | 314 | $3.00K | 0.00% | −7−2.2% | Reduced |
| Principal Securities, Inc. | 252 | $2.23K | 0.00% | +252 | New |