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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Prime Medicine, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
105
+22 vs. Q3 2023
Shares held
48.7M
−826.1K (−1.7%) vs. Q3 2023
Total value
$431.4M
−$40.8M (−8.6%) vs. Q3 2023
New holders
34
26 more added
Sold out
12
27 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 105 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value heldQ4 2023: $431.4M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q3 2023.

Institutions holding PRME in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Glassman Wealth Services103$9130.00%+103New
GAMMA Investing LLC118$7490.00%+118New
Nisa Investment Advisors, LLC24$2130.00%+4+20.0%Added
Covestor Ltd15$00.00%+7+87.5%Added
CWM, LLC46$00.00%+46New
EcoR1 Capital, LLC0$00.00%−600,000−100.0%Sold out
Moore Capital Management, LP0$00.00%−446,733−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−128,876−100.0%Sold out
Janus Henderson Group PLC0$00.00%−120,946−100.0%Sold out
Profund Advisors LLC0$00.00%−21,995−100.0%Sold out
Penserra Capital Management LLC0$00.00%−18,468−100.0%Sold out
Virtu Financial LLC0$00.00%−12,466−100.0%Sold out
Citadel Advisors LLC0$00.00%−6,524−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−3,067−100.0%Sold out
US Bancorp0$00.00%−346−100.0%Sold out
Grove Bank & Trust0$00.00%−77−100.0%Sold out
Massmutual Trust Co FSB0$00.00%−25−100.0%Sold out