Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Prime Medicine, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 66
- +66 vs. Q3 2022
- Shares held
- 41.3M
- +41.3M vs. Q3 2022
- Total value
- $767.8M
- +$767.8M vs. Q3 2022
- New holders
- 66
- 0 more added
- Sold out
- 0
- 0 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 13,284,688 | $246.8M | 14.34% | +13,284,688 | New |
| FMR LLC | 8,463,046 | $157.2M | 0.02% | +8,463,046 | New |
| Price T Rowe Associates Inc | 2,378,582 | $44.2M | 0.01% | +2,378,582 | New |
| Redmile Group, LLC | 2,209,350 | $41.0M | 1.68% | +2,209,350 | New |
| MWG Management Limited | 1,835,876 | $34.1M | 17.42% | +1,835,876 | New |
| FIL Ltd | 1,805,558 | $33.5M | 0.04% | +1,805,558 | New |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,639,984 | $30.5M | 0.26% | +1,639,984 | New |
| BlackRock Inc. | 1,487,846 | $27.6M | 0.00% | +1,487,846 | New |
| Baker Bros. Advisors LP | 1,028,466 | $19.1M | 0.11% | +1,028,466 | New |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $16.4M | 0.34% | +885,314 | New |
| Vanguard Group Inc | 872,523 | $16.2M | 0.00% | +872,523 | New |
| Casdin Capital, LLC | 734,350 | $13.6M | 1.07% | +734,350 | New |
| Cormorant Asset Management, LP | 734,350 | $13.6M | 0.92% | +734,350 | New |
| EcoR1 Capital, LLC | 600,000 | $11.1M | 0.34% | +600,000 | New |
| Moore Capital Management, LP | 500,000 | $9.29M | 0.26% | +500,000 | New |
| Sumitomo Mitsui Trust Holdings, Inc. | 488,226 | $9.07M | 0.01% | +488,226 | New |
| Nikko Asset Management Americas, Inc. | 488,226 | $9.04M | 0.13% | +488,226 | New |
| Samsara BioCapital, LLC | 470,304 | $8.74M | 1.88% | +470,304 | New |
| Geode Capital Management, LLC | 234,295 | $4.35M | 0.00% | +234,295 | New |
| Ensign Peak Advisors, Inc | 150,000 | $2.79M | 0.01% | +150,000 | New |
| OUP Management Co., LLC | 121,255 | $2.25M | 3.68% | +121,255 | New |
| State Street Corp | 114,846 | $2.13M | 0.00% | +114,846 | New |
| Caas Capital Management LP | 89,331 | $1.66M | 0.32% | +89,331 | New |
| Northern Trust Corp | 83,546 | $1.55M | 0.00% | +83,546 | New |
| Charles Schwab Investment Management Inc | 71,184 | $1.32M | 0.00% | +71,184 | New |
| Ghisallo Capital Management LLC | 70,000 | $1.30M | 0.23% | +70,000 | New |
| Laurion Capital Management LP | 60,000 | $1.11M | 0.03% | +60,000 | New |
| Manufacturers Life Insurance Company, The | 44,989 | $887.5K | 0.00% | +44,989 | New |
| Bank of America Corp | 47,359 | $879.9K | 0.00% | +47,359 | New |
| Point72 Middle East FZE | 37,609 | $698.8K | 0.05% | +37,609 | New |
| Brandywine Managers, LLC | 32,977 | $612.7K | 2.14% | +32,977 | New |
| Walleye Capital LLC | 30,000 | $557.4K | 0.01% | +30,000 | New |
| Bank of New York Mellon Corp | 29,016 | $539.1K | 0.00% | +29,016 | New |
| TD Asset Management Inc | 23,922 | $444.5K | 0.00% | +23,922 | New |
| Morgan Stanley | 20,389 | $378.8K | 0.00% | +20,389 | New |
| LMR Partners LLP | 17,760 | $330.0K | 0.01% | +17,760 | New |
| Clarius Group, LLC | 16,080 | $299.0K | 0.03% | +16,080 | New |
| Nuveen Asset Management, LLC | 14,128 | $262.0K | 0.00% | +14,128 | New |
| Oppenheimer & Co Inc | 14,012 | $260.3K | 0.01% | +14,012 | New |
| Levin Capital Strategies, L.P. | 10,585 | $196.7K | 0.03% | +10,585 | New |
| Sandia Investment Management LP | 10,000 | $185.8K | 0.03% | +10,000 | New |
| JPMorgan Chase & Co | 9,874 | $184.0K | 0.00% | +9,874 | New |
| Penserra Capital Management LLC | 7,570 | $140.0K | 0.00% | +7,570 | New |
| MetLife Investment Management | 6,091 | $113.2K | 0.00% | +6,091 | New |
| Advisor Group Holdings, Inc. | 6,029 | $112.4K | 0.00% | +6,029 | New |
| New York State Common Retirement Fund | 5,000 | $92.9K | 0.00% | +5,000 | New |
| American International Group, Inc. | 4,909 | $91.2K | 0.00% | +4,909 | New |
| Deutsche Bank AG | 4,473 | $83.1K | 0.00% | +4,473 | New |
| California State Teachers Retirement System | 4,144 | $77.0K | 0.00% | +4,144 | New |
| Alpha Paradigm Partners, LLC | 3,895 | $72.0K | 0.03% | +3,895 | New |
| Citigroup Inc | 3,587 | $66.6K | 0.00% | +3,587 | New |
| Barclays PLC | 2,787 | $51.8K | 0.00% | +2,787 | New |
| STRS Ohio | 2,400 | $44.0K | 0.00% | +2,400 | New |
| First Horizon Advisors, Inc. | 1,813 | $33.7K | 0.00% | +1,813 | New |
| Amalgamated Bank | 1,567 | $29.0K | 0.00% | +1,567 | New |
| Royal Bank of Canada | 1,547 | $28.0K | 0.00% | +1,547 | New |
| UBS Group AG | 1,209 | $22.5K | 0.00% | +1,209 | New |
| Cubist Systematic Strategies, LLC | 1,124 | $20.9K | 0.00% | +1,124 | New |
| Legal & General Group Plc | 925 | $17.1K | 0.00% | +925 | New |
| Credit Suisse AG | 800 | $14.9K | 0.00% | +800 | New |
| Ameritas Investment Partners, Inc. | 831 | $13.9K | 0.00% | +831 | New |
| Metropolitan Life Insurance Co | 718 | $13.3K | 0.00% | +718 | New |
| Chelsea Counsel Co | 600 | $11.1K | 0.01% | +600 | New |
| Tower Research Capital LLC (TRC) | 373 | $7.00K | 0.00% | +373 | New |
| Leonteq Securities AG | 200 | $3.72K | 0.00% | +200 | New |
| Benjamin Edwards Inc | 147 | $3.00K | 0.00% | +147 | New |