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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Prime Medicine, Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
0 filings
Open-market sells
0 filings
Insiders trading
0
Net value
$0
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Prime Medicine, Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Prime Medicine, Inc.
NameTitleLast reported holdingLast filingFilings, past year
Nelsen RobertDirector, 10% Owner6,230,300IndirectJun 8, 20261
Foster-Cheek Kaye IDirector–Jun 8, 20261
Schenkein David PDirector–Jun 8, 20261
Marrazzo Jeffrey DDirector–Jun 8, 20261
Kelly Michael AaronDirector–Jun 8, 20261
Chung WendyDirector–Jun 8, 20261
Cahill ThomasDirector5,305,679IndirectJun 8, 20261
Makhni Svetlana NiChief Financial Officer–Apr 17, 20261
Reine AllanChief Executive Officer125,000Feb 27, 20261
Alenson CarmanSee Remarks–Feb 24, 20261
Lee Ann L.Chief Technical Officer100,000Feb 24, 20261
Alphabet Inc.10% Owner3,262,440IndirectAug 5, 20250
GV 2021, L.P.10% Owner3,262,440IndirectAug 5, 20250
GV 2021 GP, L.L.C.10% Owner3,262,440IndirectAug 5, 20250
GV 2021 GP, L.P.10% Owner3,262,440IndirectAug 5, 20250
ARCH Venture Fund XII, L.P.10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Partners XII, LLC10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Partners XII, L.P.10% Owner6,230,300IndirectAug 1, 20250
Crandell Keith10% Owner6,230,300IndirectAug 1, 20250
Gillis Steven10% Owner6,230,300IndirectAug 1, 20250
Burow Kristina10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Fund X, L.P.10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Fund X Overage, L.P.10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Partners X Overage, L.P.10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Partners X, LLC10% Owner6,230,300IndirectAug 1, 20250
ARCH Venture Partners X, L.P.10% Owner6,230,300IndirectAug 1, 20250
Liu David R.10% Owner20,240,945Jul 1, 20250
Brudnick RichardChief Business Officer20,000May 22, 20250
Gottesdiener Keith MichaelSee Remarks682,259IndirectMay 12, 20250
Duffield JeremyChief Scientific Officer–Mar 3, 20250
Goldwasser MeredithSVP, Strategy & Corporate Ops.–Mar 3, 20250
GV 2019 GP, L.L.C.10% Owner0IndirectJun 22, 20230
GV 2019 GP, L.P.10% Owner0IndirectJun 22, 20230
GV 2019, L.P.10% Owner0IndirectJun 22, 20230
FMR LLCOther: See Remark 14,228,589IndirectOct 26, 20220

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Aug 5, 2025 (view filing)4:07 PM ETAug 14 daysAlphabet Inc. and 3 others10% OwnerPPurchase+1.50M$3.30+$4.95M+85.1%3.26M after
Aug 1, 2025 (view filing)7:19 PM ETAug 1Same dayARCH Venture Fund XII, L.P. and 2 others10% OwnerPPurchase+3.03M$3.30+$10.0M+94.7%6.23M afterDuplicate filing
Aug 1, 2025 (view filing)7:18 PM ETAug 1Same dayCrandell Keith and 7 others10% OwnerPPurchase+3.03M$3.30+$10.0M+94.7%6.23M afterDuplicate filing
Aug 1, 2025 (view filing)Aug 1Same dayNelsen RobertDirector, 10% OwnerPPurchase+3.03M$3.30+$10.0M+94.7%6.23M after
Jul 1, 2025 (view filing)Jun 301 dayLiu David R.10% OwnerPPurchase+21.0K$2.52+$52.9K+0.1%20.2M after10b5-1
Jun 23, 2025 (view filing)Jun 23Same dayLiu David R.10% OwnerPPurchase+21.0K$2.16+$45.4K+0.1%20.2M after10b5-1
Jun 16, 2025 (view filing)Jun 16Same dayLiu David R.10% OwnerPPurchase+21.0K$1.49+$31.3K+0.1%20.2M after10b5-1
Jun 12, 2025 (view filing)Jun 111 dayLiu David R.10% OwnerPPurchase+21.0K$1.60+$33.6K+0.1%20.2M after10b5-1
May 22, 2025 (view filing)May 202 daysBrudnick RichardChief Business OfficerPPurchase+20.0K$1.19+$23.8KNew position20.0K after
May 22, 2025 (view filing)May 211 dayLee Ann L.Chief Technical OfficerPPurchase+100.0K$1.13+$113.0KNew position100.0K after
May 22, 2025 (view filing)May 211 dayReine AllanChief Executive OfficerPPurchase+125.0K$1.18+$147.5KNew position125.0K after
Feb 20, 2024 (view filing)5:38 PM ETFeb 155 daysARCH Venture Fund XII, L.P. and 2 others10% OwnerPPurchase+3.20M$6.25+$20.0MNew position3.20M afterDuplicate filing
Feb 20, 2024 (view filing)5:37 PM ETFeb 155 daysCrandell Keith and 7 others10% OwnerPPurchase+3.20M$6.25+$20.0MNew position3.20M afterDuplicate filing
Feb 20, 2024 (view filing)Feb 155 daysNelsen RobertDirector, 10% OwnerPPurchase+3.20M$6.25+$20.0MNew position3.20M after
Jun 22, 2023 (view filing)5:03 PM ETJun 20-212 daysAlphabet Inc. and 6 others10% OwnerSSale−56.4K$15.03−$847.7K−100.0%0 after2 lots10b5-1
Jun 20, 2023 (view filing)4:17 PM ETJun 15-165 daysAlphabet Inc. and 6 others10% OwnerSSale−73.2K$14.93−$1.09M−100.0%0 after2 lots10b5-1
Jun 15, 2023 (view filing)4:22 PM ETJun 13-142 daysAlphabet Inc. and 6 others10% OwnerSSale−57.1K$15.00−$855.8K−100.0%0 after2 lots10b5-1
Jun 13, 2023 (view filing)4:20 PM ETJun 9-124 daysAlphabet Inc. and 6 others10% OwnerSSale−31.7K$14.73−$467.1K−100.0%0 after2 lots10b5-1
Jun 9, 2023 (view filing)4:24 PM ETJun 7-82 daysAlphabet Inc. and 6 others10% OwnerSSale−20.0K$16.63−$332.6K−100.0%0 after2 lots10b5-1
Jun 7, 2023 (view filing)4:17 PM ETJun 5-62 daysAlphabet Inc. and 6 others10% OwnerSSale−52.4K$16.88−$884.8K−100.0%0 after2 lots10b5-1
Jun 2, 2023 (view filing)4:17 PM ETMay 31-Jun 12 daysAlphabet Inc. and 6 others10% OwnerSSale−61.9K$14.17−$876.2K−100.0%0 after3 lots10b5-1
May 31, 2023 (view filing)4:15 PM ETMay 26-305 daysAlphabet Inc. and 6 others10% OwnerSSale−29.4K$13.70−$402.8K−100.0%0 after2 lots10b5-1
May 26, 2023 (view filing)4:17 PM ETMay 24-252 daysAlphabet Inc. and 6 others10% OwnerSSale−31.1K$13.45−$417.9K−100.0%0 after2 lots10b5-1
May 24, 2023 (view filing)5:07 PM ETMay 22-232 daysAlphabet Inc. and 6 others10% OwnerSSale−131.9K$14.33−$1.89M−100.0%0 after2 lots10b5-1
May 22, 2023 (view filing)4:21 PM ETMay 18-194 daysAlphabet Inc. and 6 others10% OwnerSSale−90.3K$13.62−$1.23M−100.0%0 after3 lots10b5-1
May 18, 2023 (view filing)4:16 PM ETMay 16-172 daysAlphabet Inc. and 6 others10% OwnerSSale−65.6K$12.63−$829.3K−0.6%10.7M after2 lots10b5-1
May 16, 2023 (view filing)4:16 PM ETMay 12-154 daysAlphabet Inc. and 6 others10% OwnerSSale−185.2K$12.74−$2.36M−1.7%10.8M after2 lots10b5-1
May 12, 2023 (view filing)4:16 PM ETMay 10-112 daysAlphabet Inc. and 6 others10% OwnerSSale−114.0K$13.82−$1.58M−1.0%11.0M after3 lots10b5-1
May 10, 2023 (view filing)4:17 PM ETMay 8-92 daysAlphabet Inc. and 6 others10% OwnerSSale−422.0K$14.09−$5.95M−3.7%11.1M after2 lots10b5-1
Oct 26, 2022 (view filing)8:02 PM ETOct 242 daysAlphabet Inc. and 6 othersOther: Member of a 10% GroupPPurchase+800.0K$17.00+$13.6M+7.5%11.5M after
Oct 26, 2022 (view filing)8:01 PM ETOct 242 daysCrandell Keith and 7 others10% OwnerPPurchase+800.0K$17.00+$13.6M+15.0%6.13M after2 lotsDuplicate filing
Oct 26, 2022 (view filing)Oct 242 daysNelsen RobertDirector, 10% OwnerPPurchase+800.0K$17.00+$13.6M+15.0%6.13M after2 lots
Oct 26, 2022 (view filing)Oct 242 daysCahill ThomasDirectorPPurchase+400.0K$17.00+$6.80M+8.2%5.31M after