Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2023
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 79
- +3 vs. Q1 2023
- Shares held
- 46.1M
- −4.13M (−8.2%) vs. Q1 2023
- Total value
- $675.7M
- +$58.8M (+9.5%) vs. Q1 2023
- New holders
- 16
- 36 more added
- Sold out
- 13
- 13 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $340.4M |
| Q3 2025 | 167 | $512.0M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.5M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $266.0M |
| Q2 2024 | 122 | $354.2M |
| Q1 2024 | 115 | $469.7M |
| Q4 2023 | 105 | $433.7M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $616.9M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 11,862,498 | $173.8M | 9.34% | −1,422,190−10.7% | Reduced |
| FMR LLC | 4,039,219 | $59.2M | 0.00% | −12,995,039−76.3% | Reduced |
| Vanguard Group Inc | 3,334,483 | $48.9M | 0.00% | +2,450,037+277.0% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,063,751 | $44.9M | 0.03% | +2,066,179+207.1% | Added |
| Nikko Asset Management Americas, Inc. | 3,064,616 | $44.8M | 0.47% | +2,065,283+206.7% | Added |
| BlackRock Inc. | 2,889,216 | $42.3M | 0.00% | +1,375,093+90.8% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,449,199 | $35.9M | 0.24% | +526,922+27.4% | Added |
| Price T Rowe Associates Inc | 2,333,831 | $34.2M | 0.00% | +1,430,090+158.2% | Added |
| FIL Ltd | 1,805,558 | $26.5M | 0.03% | 00.0% | Unchanged |
| MWG Management Limited | 1,792,210 | $26.3M | 15.88% | −43,666−2.4% | Reduced |
| Redmile Group, LLC | 1,324,350 | $19.4M | 0.74% | −668,493−33.5% | Reduced |
| Baker Bros. Advisors LP | 1,028,466 | $15.1M | 0.09% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $13.0M | 0.28% | 00.0% | Unchanged |
| State Street Corp | 605,199 | $8.87M | 0.00% | +415,771+219.5% | Added |
| EcoR1 Capital, LLC | 600,000 | $8.79M | 0.23% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 564,854 | $8.27M | 0.01% | +550,763+3,908.6% | Added |
| Geode Capital Management, LLC | 540,308 | $7.92M | 0.00% | +299,963+124.8% | Added |
| Samsara BioCapital, LLC | 470,304 | $6.89M | 1.21% | 00.0% | Unchanged |
| Moore Capital Management, LP | 446,733 | $6.54M | 0.16% | −53,267−10.7% | Reduced |
| Jane Street Group, LLC | 397,004 | $5.82M | 0.01% | +397,004 | New |
| Casdin Capital, LLC | 367,175 | $5.38M | 0.47% | −367,175−50.0% | Reduced |
| Northern Trust Corp | 282,431 | $4.14M | 0.00% | +192,352+213.5% | Added |
| Millennium Management LLC | 256,560 | $3.76M | 0.00% | +245,801+2,284.6% | Added |
| Greenwich Wealth Management LLC | 208,000 | $3.05M | 0.32% | −141,000−40.4% | Reduced |
| Ensign Peak Advisors, Inc | 150,000 | $2.20M | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 147,515 | $2.16M | 0.00% | −2,752−1.8% | Reduced |
| Charles Schwab Investment Management Inc | 141,144 | $2.07M | 0.00% | +67,717+92.2% | Added |
| Nuveen Asset Management, LLC | 123,195 | $1.80M | 0.00% | +109,067+772.0% | Added |
| Bank of New York Mellon Corp | 103,213 | $1.51M | 0.00% | +73,145+243.3% | Added |
| UBS Group AG | 99,039 | $1.45M | 0.00% | +94,104+1,906.9% | Added |
| TD Asset Management Inc | 67,071 | $982.6K | 0.00% | +43,149+180.4% | Added |
| Manufacturers Life Insurance Company, The | 58,401 | $855.6K | 0.00% | +12,770+28.0% | Added |
| Morgan Stanley | 57,929 | $848.7K | 0.00% | +24,544+73.5% | Added |
| Laurion Capital Management LP | 55,888 | $818.8K | 0.04% | −4,112−6.9% | Reduced |
| Rhumbline Advisers | 47,063 | $689.5K | 0.00% | +47,063 | New |
| Brandywine Managers, LLC | 32,977 | $483.1K | 0.32% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 30,672 | $449.3K | 0.00% | +17,775+137.8% | Added |
| Alliancebernstein L.P. | 26,540 | $388.8K | 0.00% | +26,540 | New |
| MetLife Investment Management | 21,262 | $311.5K | 0.00% | +15,171+249.1% | Added |
| HighTower Advisors, LLC | 21,322 | $310.0K | 0.00% | +21,322 | New |
| Levin Capital Strategies, L.P. | 20,000 | $293.0K | 0.03% | +20,000 | New |
| American International Group, Inc. | 19,040 | $278.9K | 0.00% | +13,953+274.3% | Added |
| Mirae Asset Global Investments Co., Ltd. | 18,871 | $276.5K | 0.00% | +18,871 | New |
| Principal Financial Group Inc | 18,029 | $264.1K | 0.00% | +18,029 | New |
| Deutsche Bank AG | 17,812 | $260.9K | 0.00% | +6,952+64.0% | Added |
| Wells Fargo & Company | 16,297 | $238.8K | 0.00% | +14,361+741.8% | Added |
| Clarius Group, LLC | 16,080 | $235.6K | 0.02% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 15,984 | $234.2K | 0.00% | +8,191+105.1% | Added |
| Voya Investment Management LLC | 15,743 | $230.6K | 0.00% | +15,743 | New |
| Oppenheimer & Co Inc | 15,385 | $225.4K | 0.00% | +267+1.8% | Added |
| Red Lighthouse Investment Management, LLC | 14,950 | $219.0K | 0.10% | 00.0% | Unchanged |
| Citigroup Inc | 14,161 | $207.5K | 0.00% | +5,302+59.8% | Added |
| California State Teachers Retirement System | 13,159 | $192.8K | 0.00% | −7,808−37.2% | Reduced |
| Green Alpha Advisors, LLC | 12,386 | $181.5K | 0.12% | +12,386 | New |
| Susquehanna International Group, LLP | 12,254 | $179.5K | 0.00% | +12,254 | New |
| Allspring Global Investments Holdings, LLC | 11,441 | $167.6K | 0.00% | +10,290+894.0% | Added |
| State Board of Administration of Florida Retirement System | 11,230 | $164.5K | 0.00% | +11,230 | New |
| Brown Brothers Harriman & Co | 10,065 | $147.5K | 0.00% | +10,065 | New |
| Sandia Investment Management LP | 10,000 | $146.5K | 0.04% | 00.0% | Unchanged |
| Penserra Capital Management LLC | 8,107 | $118.0K | 0.00% | +1,107+15.8% | Added |
| Barclays PLC | 7,879 | $115.4K | 0.00% | +2,543+47.7% | Added |
| Advisor Group Holdings, Inc. | 6,403 | $93.8K | 0.00% | −28−0.4% | Reduced |
| ORG Partners LLC | 5,270 | $76.4K | 0.01% | +5,270 | New |
| Legal & General Group Plc | 4,791 | $70.2K | 0.00% | +1,364+39.8% | Added |
| Amalgamated Bank | 4,752 | $70.0K | 0.00% | +3,488+275.9% | Added |
| Royal Bank of Canada | 3,579 | $53.0K | 0.00% | +2,989+506.6% | Added |
| Ameritas Investment Partners, Inc. | 3,267 | $47.9K | 0.00% | +2,436+293.1% | Added |
| Tower Research Capital LLC (TRC) | 3,143 | $46.0K | 0.00% | −82−2.5% | Reduced |
| Metropolitan Life Insurance Co | 2,203 | $32.3K | 0.00% | +1,485+206.8% | Added |
| Lazard Asset Management LLC | 1,604 | $23.0K | 0.00% | +57+3.7% | Added |
| First Horizon Advisors, Inc. | 1,555 | $22.8K | 0.00% | −143−8.4% | Reduced |
| Chelsea Counsel Co | 600 | $8.79K | 0.00% | 00.0% | Unchanged |
| Endurance Wealth Management, Inc. | 500 | $8.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 346 | $5.07K | 0.00% | +346 | New |
| Benjamin Edwards Inc | 321 | $5.00K | 0.00% | +139+76.4% | Added |
| Massmutual Trust Co FSB | 34 | $498 | 0.00% | +34 | New |
| Nisa Investment Advisors, LLC | 33 | $483 | 0.00% | +33 | New |
| CWM, LLC | 15 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 9 | $0 | 0.00% | 00.0% | Unchanged |
| Cormorant Asset Management, LP | 0 | $0 | 0.00% | −734,350−100.0% | Sold out |
| Wexford Capital LP | 0 | $0 | 0.00% | −153,705−100.0% | Sold out |
| OUP Management Co., LLC | 0 | $0 | 0.00% | −121,255−100.0% | Sold out |
| Swiss National Bank | 0 | $0 | 0.00% | −41,900−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −32,500−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −32,197−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −19,663−100.0% | Sold out |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −17,999−100.0% | Sold out |
| Credit Suisse AG | 0 | $0 | 0.00% | −14,705−100.0% | Sold out |
| Capstone Investment Advisors, LLC | 0 | $0 | 0.00% | −14,551−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −7,200−100.0% | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −231−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −45−100.0% | Sold out |