Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Prime Medicine, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 116
- −3 vs. Q2 2024
- Shares held
- 68.7M
- +5.01M (+7.9%) vs. Q2 2024
- Total value
- $265.9M
- −$61.5M (−18.8%) vs. Q2 2024
- New holders
- 15
- 38 more added
- Sold out
- 18
- 33 more reduced
3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alphabet Inc. | 15,062,498 | $58.3M | 3.16% | 00.0% | Unchanged |
| ARK Investment Management LLCSuperinvestorARK Invest | 5,660,719 | $21.9M | 0.20% | −466,054−7.6% | Reduced |
| BlackRock, Inc. | 5,266,775 | $20.4M | 0.00% | +5,266,775 | New |
| Vanguard Group Inc | 4,890,313 | $18.9M | 0.00% | −1,188,540−19.6% | Reduced |
| T. Rowe Price Investment Management, Inc. | 3,807,287 | $14.7M | 0.01% | +81,560+2.2% | Added |
| FMR LLC | 3,743,312 | $14.5M | 0.00% | −184,541−4.7% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,190,455 | $12.3M | 0.01% | −47,930−1.5% | Reduced |
| Nikko Asset Management Americas, Inc. | 3,182,455 | $12.3M | 0.14% | −55,930−1.7% | Reduced |
| Millennium Management LLC | 2,198,240 | $8.51M | 0.01% | +867,313+65.2% | Added |
| Redmile Group, LLC | 2,074,350 | $8.03M | 0.47% | 00.0% | Unchanged |
| MWG Management Limited | 1,792,210 | $6.94M | 7.68% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 1,545,961 | $5.98M | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,359,979 | $5.26M | 0.00% | +63,456+4.9% | Added |
| State Street Corp | 1,146,949 | $4.44M | 0.00% | +43,086+3.9% | Added |
| Vestal Point Capital, LP | 1,070,000 | $4.14M | 0.33% | +620,000+137.8% | Added |
| Baker Bros. Advisors LP | 1,028,466 | $3.98M | 0.04% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 896,960 | $3.47M | 0.05% | 00.0% | Unchanged |
| Farallon Capital Management, L.L.C. | 750,000 | $2.90M | 0.02% | 00.0% | Unchanged |
| Greenwich Wealth Management LLC | 733,001 | $2.84M | 0.19% | +80,000+12.3% | Added |
| EcoR1 Capital, LLC | 700,000 | $2.71M | 0.09% | 00.0% | Unchanged |
| Avidity Partners Management LP | 694,000 | $2.69M | 0.14% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 540,304 | $2.09M | 0.40% | 00.0% | Unchanged |
| Northern Trust Corp | 524,548 | $2.03M | 0.00% | +131,031+33.3% | Added |
| Moore Capital Management, LP | 500,000 | $1.94M | 0.06% | 00.0% | Unchanged |
| Bank of America Corp | 485,125 | $1.88M | 0.00% | +57,729+13.5% | Added |
| Charles Schwab Investment Management Inc | 463,977 | $1.80M | 0.00% | −28,284−5.7% | Reduced |
| Westwood Holdings Group Inc. | 449,476 | $1.74M | 0.01% | +90,896+25.3% | Added |
| Nuveen Asset Management, LLC | 392,443 | $1.52M | 0.00% | 00.0% | Unchanged |
| Casdin Capital, LLC | 367,175 | $1.42M | 0.09% | 00.0% | Unchanged |
| Bollard Group LLC | 361,136 | $1.40M | 0.04% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 318,573 | $1.23M | 0.00% | −362,903−53.3% | Reduced |
| Morgan Stanley | 300,391 | $1.16M | 0.00% | +116,426+63.3% | Added |
| Trexquant Investment LP | 242,160 | $937.2K | 0.01% | +13,945+6.1% | Added |
| Goldman Sachs Group Inc | 220,144 | $852.0K | 0.00% | +140,777+177.4% | Added |
| Wells Fargo & Company | 171,468 | $663.6K | 0.00% | +151,110+742.3% | Added |
| D. E. Shaw & Co., Inc. | 139,451 | $539.7K | 0.00% | +94,016+206.9% | Added |
| FIL Ltd | 129,861 | $502.6K | 0.00% | −8,415−6.1% | Reduced |
| Bank of New York Mellon Corp | 129,714 | $502.0K | 0.00% | −40,849−23.9% | Reduced |
| Squarepoint Ops LLC | 124,369 | $481.3K | 0.00% | +60,908+96.0% | Added |
| Two Sigma Advisers, LP | 119,900 | $464.0K | 0.00% | −56,600−32.1% | Reduced |
| Susquehanna International Group, LLP | 115,054 | $445.3K | 0.00% | +9,162+8.7% | Added |
| Deutsche Bank AG | 114,907 | $444.7K | 0.00% | −346,088−75.1% | Reduced |
| Walleye Capital LLC | 108,374 | $419.4K | 0.00% | +108,374 | New |
| Gsa Capital Partners LLP | 99,060 | $383.0K | 0.03% | +99,060 | New |
| Vestmark Advisory Solutions, Inc. | 90,036 | $348.4K | 0.01% | −13,476−13.0% | Reduced |
| Barclays PLC | 84,697 | $327.8K | 0.00% | +65,593+343.3% | Added |
| Chelsea Counsel Co | 78,690 | $304.5K | 0.15% | +1,000+1.3% | Added |
| Sphera Funds Management Ltd. | 76,456 | $295.9K | 0.05% | −50,968−40.0% | Reduced |
| Alliancebernstein L.P. | 76,000 | $294.1K | 0.00% | +5,810+8.3% | Added |
| Rhumbline Advisers | 70,047 | $271.1K | 0.00% | −60−0.1% | Reduced |
| Jane Street Group, LLC | 57,548 | $222.7K | 0.00% | −110,869−65.8% | Reduced |
| Citadel Advisors LLC | 50,995 | $197.4K | 0.00% | +38,269+300.7% | Added |
| Citigroup Inc | 48,071 | $186.0K | 0.00% | +30,560+174.5% | Added |
| SG Americas Securities, LLC | 46,982 | $182.0K | 0.00% | +46,982 | New |
| PEAK6 Investments LLC | 45,013 | $174.2K | 0.01% | +11,013+32.4% | Added |
| TD Asset Management Inc | 46,434 | $160.7K | 0.00% | 00.0% | Unchanged |
| Verition Fund Management LLC | 38,545 | $149.2K | 0.00% | +38,545 | New |
| JPMorgan Chase & Co | 37,382 | $144.7K | 0.00% | −805−2.1% | Reduced |
| UBS Group AG | 35,021 | $135.5K | 0.00% | +12,482+55.4% | Added |
| MetLife Investment Management | 34,128 | $132.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 31,127 | $120.5K | 0.00% | +11,603+59.4% | Added |
| Corebridge Financial, Inc. | 30,325 | $117.4K | 0.00% | −187−0.6% | Reduced |
| Levin Capital Strategies, L.P. | 30,000 | $116.1K | 0.01% | +30,000 | New |
| Ameriprise Financial Inc | 28,801 | $111.5K | 0.00% | −1,095−3.7% | Reduced |
| Envestnet Asset Management Inc | 28,355 | $109.7K | 0.00% | +6,695+30.9% | Added |
| Davy Global Fund Management Ltd | 28,113 | $108.8K | 0.01% | +9,199+48.6% | Added |
| Voloridge Investment Management, LLC | 27,119 | $105.0K | 0.00% | −18,634−40.7% | Reduced |
| Manufacturers Life Insurance Company, The | 23,395 | $90.5K | 0.00% | −743−3.1% | Reduced |
| Benjamin Edwards Inc | 23,196 | $89.6K | 0.00% | +23,010+12,371.0% | Added |
| China Universal Asset Management Co., Ltd. | 23,086 | $89.3K | 0.01% | +8,985+63.7% | Added |
| HighTower Advisors, LLC | 21,675 | $83.0K | 0.00% | −559−2.5% | Reduced |
| Renaissance Technologies LLC | 20,000 | $77.4K | 0.00% | +20,000 | New |
| Corsair Capital Management, L.P. | 20,000 | $77.4K | 0.02% | +20,000 | New |
| Voya Investment Management LLC | 19,184 | $74.2K | 0.00% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 17,871 | $69.2K | 0.00% | −3,160−15.0% | Reduced |
| ProShare Advisors LLC | 17,811 | $68.9K | 0.00% | +5,104+40.2% | Added |
| Clarius Group, LLC | 16,080 | $62.2K | 0.00% | 00.0% | Unchanged |
| Pathstone Holdings, LLC | 14,370 | $55.6K | 0.00% | +14,370 | New |
| Intech Investment Management LLC | 14,102 | $54.6K | 0.00% | +14,102 | New |
| Invesco Ltd. | 14,023 | $54.3K | 0.00% | +586+4.4% | Added |
| Virtus ETF Advisers LLC | 11,670 | $45.2K | 0.02% | +211+1.8% | Added |
| Paloma Partners Management Co | 11,587 | $44.8K | 0.00% | +11,587 | New |
| State Board of Administration of Florida Retirement System | 11,420 | $44.2K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 10,886 | $42.0K | 0.00% | +10,886 | New |
| Royal Bank of Canada | 10,685 | $41.0K | 0.00% | +4,547+74.1% | Added |
| CIBC World Markets Inc. | 10,222 | $40.0K | 0.00% | −1,113−9.8% | Reduced |
| Brown Brothers Harriman & Co | 10,065 | $39.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 9,901 | $38.3K | 0.00% | −800−7.5% | Reduced |
| New York State Common Retirement Fund | 8,434 | $32.6K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 8,049 | $31.1K | 0.00% | +2,892+56.1% | Added |
| Legal & General Group Plc | 6,279 | $24.3K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 4,522 | $17.5K | 0.00% | −1,678−27.1% | Reduced |
| California State Teachers Retirement System | 4,110 | $15.9K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 3,901 | $15.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 4,341 | $15.0K | 0.00% | +757+21.1% | Added |
| Signaturefd, LLC | 1,410 | $5.46K | 0.00% | +410+41.0% | Added |
| Amalgamated Bank | 1,347 | $5.00K | 0.00% | 00.0% | Unchanged |
| Abich Financial Wealth Management LLC | 1,247 | $4.83K | 0.01% | +941+307.5% | Added |
| First Horizon Advisors, Inc. | 1,109 | $4.29K | 0.00% | −25−2.2% | Reduced |
| Quadrant Capital Group LLC | 966 | $3.74K | 0.00% | +966 | New |